List of works - Abishek Iyer

An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice.

scientific article published on 8 November 2016

An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammation.

scientific article

Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats

scientific article

C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling

scientific article

Cardiovascular changes during maturation and ageing in male and female spontaneously hypertensive rats

scientific article published in April 2011

Chemical Approaches to Modulating Complement-Mediated Diseases.

scientific article published on 4 October 2017

Crystal Structures of Protein-Bound Cyclic Peptides

scientific article published on 02 May 2019

Diet-induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism

scientific article

Differential Anti-inflammatory Activity of HDAC Inhibitors in Human Macrophages and Rat Arthritis

scientific article published on 10 December 2015

Emerging Roles for G-protein Coupled Receptors in Development and Activation of Macrophages

scientific article published on 27 August 2019

Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a

scientific article published on 24 August 2017

Fermented wheat germ extract (avemar) in the treatment of cardiac remodeling and metabolic symptoms in rats

scientific article

Green tea attenuates cardiovascular remodelling and metabolic symptoms in high carbohydrate-fed rats

scientific article published on December 2010

Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes

article

High-carbohydrate, high-fat diet-induced metabolic syndrome and cardiovascular remodeling in rats

scientific article published on 01 May 2011

Histone Deacetylase Inhibitors Promote Mitochondrial Reactive Oxygen Species Production and Bacterial Clearance by Human Macrophages.

scientific article published on 28 December 2015

Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages

scientific article

Histone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseases

scientific article

Inflammatory lipid mediators in adipocyte function and obesity.

scientific article published on February 2010

Inflammatory responses induced by lipopolysaccharide are amplified in primary human monocytes but suppressed in macrophages by complement protein C5a.

scientific article published on 16 September 2013

Inhibition of Inflammation and Fibrosis by a Complement C5a Receptor Antagonist in DOCA-Salt Hypertensive Rats

article

Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic type 2 inflammation

scientific article published on 17 August 2019

L-carnitine attenuates cardiac remodelling rather than vascular remodelling in deoxycorticosterone acetate-salt hypertensive rats

scientific article published on 11 November 2009

Lysine Deacetylases and Regulated Glycolysis in Macrophages.

scientific article

Lysine acetylation in obesity, diabetes and metabolic disease.

scientific article

Mineralocorticoid receptors mediate cardiac remodelling in morphine-dependent rats

scientific article published on 28 February 2012

Nutrient and immune sensing are obligate pathways in metabolism, immunity, and disease

scientific article published on 11 June 2015

Resveratrol improves cardiovascular function in DOCA-salt hypertensive rats

scientific article published in March 2011

The DOCA-Salt Hypertensive Rat as a Model of Cardiovascular Oxidative and Inflammatory Stress ⬇️

scientific article

The cardiovascular nutrapharmacology of resveratrol: pharmacokinetics, molecular mechanisms and therapeutic potential.

scientific article published on January 2010

Towards isozyme-selective HDAC inhibitors for interrogating disease.

scientific article published on January 2012

List of works by Abishek Iyer

An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice.

An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammation.

Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats

C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling

Cardiovascular changes during maturation and ageing in male and female spontaneously hypertensive rats

Chemical Approaches to Modulating Complement-Mediated Diseases.

Crystal Structures of Protein-Bound Cyclic Peptides

Diet-induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism

Differential Anti-inflammatory Activity of HDAC Inhibitors in Human Macrophages and Rat Arthritis

Emerging Roles for G-protein Coupled Receptors in Development and Activation of Macrophages

Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a

Fermented wheat germ extract (avemar) in the treatment of cardiac remodeling and metabolic symptoms in rats

Green tea attenuates cardiovascular remodelling and metabolic symptoms in high carbohydrate-fed rats

Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes

High-carbohydrate, high-fat diet-induced metabolic syndrome and cardiovascular remodeling in rats

Histone Deacetylase Inhibitors Promote Mitochondrial Reactive Oxygen Species Production and Bacterial Clearance by Human Macrophages.

Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages

Histone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseases

Inflammatory lipid mediators in adipocyte function and obesity.

Inflammatory responses induced by lipopolysaccharide are amplified in primary human monocytes but suppressed in macrophages by complement protein C5a.

Inhibition of Inflammation and Fibrosis by a Complement C5a Receptor Antagonist in DOCA-Salt Hypertensive Rats

Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic type 2 inflammation

L-carnitine attenuates cardiac remodelling rather than vascular remodelling in deoxycorticosterone acetate-salt hypertensive rats

Lysine Deacetylases and Regulated Glycolysis in Macrophages.

Lysine acetylation in obesity, diabetes and metabolic disease.

Mineralocorticoid receptors mediate cardiac remodelling in morphine-dependent rats

Nutrient and immune sensing are obligate pathways in metabolism, immunity, and disease

Resveratrol improves cardiovascular function in DOCA-salt hypertensive rats

The DOCA-Salt Hypertensive Rat as a Model of Cardiovascular Oxidative and Inflammatory Stress ⬇️

The cardiovascular nutrapharmacology of resveratrol: pharmacokinetics, molecular mechanisms and therapeutic potential.

Towards isozyme-selective HDAC inhibitors for interrogating disease.