List of works - Ralf Gilsbach

5'-Hydroxymethylcytosine Precedes Loss of CpG Methylation in Enhancers and Genes Undergoing Activation in Cardiomyocyte Maturation

scientific article

A Dual Noradrenergic Mechanism for the Relief of Neuropathic Allodynia by the Antidepressant Drugs Duloxetine and Amitriptyline.

scientific article published on 24 September 2018

A systemic Pasteurella multocida toxin aggravates cardiac hypertrophy and fibrosis in mice

scientific article

Ablation of biglycan attenuates cardiac hypertrophy and fibrosis after left ventricular pressure overload

scientific article

Ablation of mineralocorticoid receptors in myocytes but not in fibroblasts preserves cardiac function.

scientific article

Adrenergic Repression of the Epigenetic Reader MeCP2 Facilitates Cardiac Adaptation in Chronic Heart Failure

scientific article

Alpha2-adrenoceptor subtypes--unexpected functions for receptors and ligands derived from gene-targeted mouse models.

scientific article published on 4 July 2007

Are the pharmacology and physiology of α₂ adrenoceptors determined by α₂-heteroreceptors and autoreceptors respectively?

scientific article published on January 2012

Association of major depression with rare functional variants in norepinephrine transporter and serotonin1A receptor genes

scientific article

Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression

scientific article published on 18 February 2016

Cardiac Myocyte De Novo DNA Methyltransferases 3a/3b Are Dispensable for Cardiac Function and Remodeling after Chronic Pressure Overload in Mice

scientific article published on 22 June 2015

Cardiovascular effects of chronic treatment with a β2-adrenoceptor agonist relieving neuropathic pain in mice

scientific article published on 23 February 2011

Chronic cardiac pressure overload induces adrenal medulla hypertrophy and increased catecholamine synthesis.

scientific article

Cingulate Overexpression of Mitogen-Activated Protein Kinase Phosphatase-1 as a Key Factor for Depression

scientific article published on 14 February 2017

Comparison of in vitro and in vivo reference genes for internal standardization of real-time PCR data

scientific article

Cooperative interactions at M2 muscarinic acetylcholine receptors: structure/activity relationships in stepwise shortened bispyridinium- and bis(ammonio)alkane-type allosteric modulators

scientific article published in April 2003

DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes

scientific article published on 21 November 2017

Deciphering the Epigenetic Code of Cardiac Myocyte Transcription.

scientific article

Deoxycorticosterone Acetate/Salt-Induced Cardiac But Not Renal Injury Is Mediated By Endothelial Mineralocorticoid Receptors Independently From Blood Pressure

scientific article published on 9 November 2015

Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo.

scientific article

Dorsal BNST α2A-Adrenergic Receptors Produce HCN-Dependent Excitatory Actions That Initiate Anxiogenic Behaviors.

scientific article

Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease.

scientific article

Epigenetics in cardiac development, function, and disease.

scientific article published on 13 May 2014

Galaxy HiCExplorer: a web server for reproducible Hi-C data analysis, quality control and visualization.

scientific article published in July 2018

Gdf-15 deficiency does not alter vulnerability of nigrostriatal dopaminergic system in MPTP-intoxicated mice

scientific article

Genetic dissection of alpha2-adrenoceptor functions in adrenergic versus nonadrenergic cells

scientific article

Heterozygous alpha 2C-adrenoceptor-deficient mice develop heart failure after transverse aortic constriction.

scientific article published on 24 May 2007

Increased expression of the auxiliary beta(2)-subunit of ventricular L-type Ca(2)+ channels leads to single-channel activity characteristic of heart failure

scientific article

Induction of heart failure by minimally invasive aortic constriction in mice: reduced peroxisome proliferator-activated receptor γ coactivator levels and mitochondrial dysfunction

scientific article published on 05 May 2010

Interleukin-4 Protects Dopaminergic Neurons In vitro but Is Dispensable for MPTP-Induced Neurodegeneration In vivo

scientific article published on 9 March 2017

Involvement of α2-adrenoceptor subtypes A and C in glucose homeostasis and adrenaline-induced hyperglycaemia

scientific article published on 7 February 2012

MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria.

scientific article published in October 2016

Modulation of alpha2-adrenoceptor functions by heterotrimeric Galphai protein isoforms

scientific article

Molecular cloning and functional expression of the murine noradrenaline transporter

scientific article

Neuropeptide Y in the noradrenergic neurones induces obesity and inhibits sympathetic tone in mice

scientific article published on 26 December 2014

Neurotrophin and neuropeptide expression in mouse brain is regulated by knockout of the norepinephrine transporter

scientific article published on 12 March 2008

Noncanonical G-protein-dependent modulation of osteoclast differentiation and bone resorption mediated by Pasteurella multocida toxin

scientific article

Norepinephrine transporter knockout-induced up-regulation of brain alpha2A/C-adrenergic receptors.

scientific article published on 17 January 2006

Pre- versus Postsynaptic Signaling by α2-Adrenoceptors

scientific article published on January 1, 2011

REEP1 and REEP2 proteins are preferentially expressed in neuronal and neuronal-like exocytotic tissues.

scientific article published on 16 December 2013

Sympathetic alpha(2)-adrenoceptors prevent cardiac hypertrophy and fibrosis in mice at baseline but not after chronic pressure overload

scientific article published on 18 January 2010

Transgenic simulation of human heart failure-like L-type Ca2+-channels: implications for fibrosis and heart rate in mice.

scientific article published on 20 July 2009

Upregulation of Soluble Vascular Endothelial Growth Factor Receptor 1 Contributes to Angiogenesis Defects in the Placenta of α 2B -Adrenoceptor–Deficient Mice

article published in 2007

[α -Adrenoceptors: three subtypes for a broad spectrum of activity]

scientific article published on 01 November 2011

{Alpha}2B-adrenoceptor deficiency leads to postnatal respiratory failure in mice

scientific article published on 20 August 2010

β1-Adrenoceptor mRNA level reveals distinctions between infantile hemangioma and vascular malformations

scientific article

List of works by Ralf Gilsbach

5'-Hydroxymethylcytosine Precedes Loss of CpG Methylation in Enhancers and Genes Undergoing Activation in Cardiomyocyte Maturation

A Dual Noradrenergic Mechanism for the Relief of Neuropathic Allodynia by the Antidepressant Drugs Duloxetine and Amitriptyline.

A systemic Pasteurella multocida toxin aggravates cardiac hypertrophy and fibrosis in mice

Ablation of biglycan attenuates cardiac hypertrophy and fibrosis after left ventricular pressure overload

Ablation of mineralocorticoid receptors in myocytes but not in fibroblasts preserves cardiac function.

Adrenergic Repression of the Epigenetic Reader MeCP2 Facilitates Cardiac Adaptation in Chronic Heart Failure

Alpha2-adrenoceptor subtypes--unexpected functions for receptors and ligands derived from gene-targeted mouse models.

Are the pharmacology and physiology of α₂ adrenoceptors determined by α₂-heteroreceptors and autoreceptors respectively?

Association of major depression with rare functional variants in norepinephrine transporter and serotonin1A receptor genes

Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression

Cardiac Myocyte De Novo DNA Methyltransferases 3a/3b Are Dispensable for Cardiac Function and Remodeling after Chronic Pressure Overload in Mice

Cardiovascular effects of chronic treatment with a β2-adrenoceptor agonist relieving neuropathic pain in mice

Chronic cardiac pressure overload induces adrenal medulla hypertrophy and increased catecholamine synthesis.

Cingulate Overexpression of Mitogen-Activated Protein Kinase Phosphatase-1 as a Key Factor for Depression

Comparison of in vitro and in vivo reference genes for internal standardization of real-time PCR data

Cooperative interactions at M2 muscarinic acetylcholine receptors: structure/activity relationships in stepwise shortened bispyridinium- and bis(ammonio)alkane-type allosteric modulators

DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes

Deciphering the Epigenetic Code of Cardiac Myocyte Transcription.

Deoxycorticosterone Acetate/Salt-Induced Cardiac But Not Renal Injury Is Mediated By Endothelial Mineralocorticoid Receptors Independently From Blood Pressure

Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo.

Dorsal BNST α2A-Adrenergic Receptors Produce HCN-Dependent Excitatory Actions That Initiate Anxiogenic Behaviors.

Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease.

Epigenetics in cardiac development, function, and disease.

Galaxy HiCExplorer: a web server for reproducible Hi-C data analysis, quality control and visualization.

Gdf-15 deficiency does not alter vulnerability of nigrostriatal dopaminergic system in MPTP-intoxicated mice

Genetic dissection of alpha2-adrenoceptor functions in adrenergic versus nonadrenergic cells

Heterozygous alpha 2C-adrenoceptor-deficient mice develop heart failure after transverse aortic constriction.

Increased expression of the auxiliary beta(2)-subunit of ventricular L-type Ca(2)+ channels leads to single-channel activity characteristic of heart failure

Induction of heart failure by minimally invasive aortic constriction in mice: reduced peroxisome proliferator-activated receptor γ coactivator levels and mitochondrial dysfunction

Interleukin-4 Protects Dopaminergic Neurons In vitro but Is Dispensable for MPTP-Induced Neurodegeneration In vivo

Involvement of α2-adrenoceptor subtypes A and C in glucose homeostasis and adrenaline-induced hyperglycaemia

MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria.

Modulation of alpha2-adrenoceptor functions by heterotrimeric Galphai protein isoforms

Molecular cloning and functional expression of the murine noradrenaline transporter

Neuropeptide Y in the noradrenergic neurones induces obesity and inhibits sympathetic tone in mice

Neurotrophin and neuropeptide expression in mouse brain is regulated by knockout of the norepinephrine transporter

Noncanonical G-protein-dependent modulation of osteoclast differentiation and bone resorption mediated by Pasteurella multocida toxin

Norepinephrine transporter knockout-induced up-regulation of brain alpha2A/C-adrenergic receptors.

Pre- versus Postsynaptic Signaling by α2-Adrenoceptors

REEP1 and REEP2 proteins are preferentially expressed in neuronal and neuronal-like exocytotic tissues.

Sympathetic alpha(2)-adrenoceptors prevent cardiac hypertrophy and fibrosis in mice at baseline but not after chronic pressure overload

Transgenic simulation of human heart failure-like L-type Ca2+-channels: implications for fibrosis and heart rate in mice.

Upregulation of Soluble Vascular Endothelial Growth Factor Receptor 1 Contributes to Angiogenesis Defects in the Placenta of α 2B -Adrenoceptor–Deficient Mice

[α -Adrenoceptors: three subtypes for a broad spectrum of activity]

{Alpha}2B-adrenoceptor deficiency leads to postnatal respiratory failure in mice

β1-Adrenoceptor mRNA level reveals distinctions between infantile hemangioma and vascular malformations