List of works - Ana Rodriguez

A Plasmodium yoelii soluble factor inhibits the phenotypic maturation of dendritic cells.

scientific article published on 15 December 2008

A high-efficiency microfluidic device for size-selective trapping and sorting

scientific article

A potential role for plasma uric acid in the endothelial pathology of Plasmodium falciparum malaria

scientific article

A putative kinase-related protein (PKRP) from Plasmodium berghei mediates infection in the midgut and salivary glands of the mosquito

scientific article

A surprising role for uric acid: the inflammatory malaria response

scientific article

Activity in vivo of anti-Trypanosoma cruzi compounds selected from a high throughput screening

scientific article

Adenylyl cyclase alpha and cAMP signaling mediate Plasmodium sporozoite apical regulated exocytosis and hepatocyte infection.

scientific article

Angiotensin II Moderately Decreases Plasmodium Infection and Experimental Cerebral Malaria in Mice

scientific article

Angiotensin receptors and β-catenin regulate brain endothelial integrity in malaria

scientific article published on 19 September 2016

Anilinoquinoline based inhibitors of trypanosomatid proliferation

scientific article published on 26 November 2018

Anti-Self Phosphatidylserine Antibodies Recognize Uninfected Erythrocytes Promoting Malarial Anemia.

scientific article published on February 2016

Anti-ganglioside antibodies in patients with Zika virus infection-associated Guillain-Barré Syndrome in Brazil

scientific article published on 17 September 2019

Antiparasitic Lead Discovery: Toward Optimization of a Chemotype with Activity Against Multiple Protozoan Parasites.

scientific article

Antitrypanosomal Lead Discovery: Identification of a Ligand-Efficient Inhibitor of Trypanosoma cruzi CYP51 and Parasite Growth

scientific article

Atypical activation of dendritic cells by Plasmodium falciparum

scientific article published on 21 November 2017

Atypical memory B-cells are associated with anemia through anti-phosphatidylserine antibodies

scientific article published on 12 November 2019

Autoantibody levels are associated with acute kidney injury, anemia and post-discharge morbidity and mortality in Ugandan children with severe malaria

scientific article published on 17 October 2019

Autoimmune Anemia in Malaria

scientific article published on 18 December 2019

Automated high-content assay for compounds selectively toxic to Trypanosoma cruzi in a myoblastic cell line

scientific article

Chemical attenuation of Plasmodium berghei sporozoites induces sterile immunity in mice.

scientific article

Chemically attenuated Plasmodium sporozoites induce specific immune responses, sterile immunity and cross-protection against heterologous challenge

scientific article published on 29 July 2008

Color capable sub-pixel resolving optofluidic microscope and its application to blood cell imaging for malaria diagnosis

scientific article

Corrigendum to "Optimization of physicochemical properties for 4-Anilinoquinazoline inhibitors of trypanosome proliferation" [Eur. J. Med. Chem. 141 (2017) 446-459]

scientific article published on 10 May 2018

Daily Plasmodium yoelii infective mosquito bites do not generate protection or suppress previous immunity against the liver stage ⬇️

scientific article

Dendritic cells can initiate protective immune responses against malaria.

scientific article published on August 2001

Discovery and Optimization of a Compound Series Active against Trypanosoma cruzi, the Causative Agent of Chagas Disease

scientific article published on 05 March 2020

Divergent Roles of Antiself Antibodies during Infection

scientific article published on 30 April 2018

Diversity-oriented synthesis yields a new drug lead for treatment of chagas disease

scientific article

Dual effect of Plasmodium-infected erythrocytes on dendritic cell maturation.

scientific article

EVALUATION OF AROMATIC 6-SUBSTITUTED THIENOPYRIMIDINES AS SCAFFOLDS AGAINST PARASITES THAT CAUSE TRYPANOSOMIASIS, LEISHMANIASIS, AND MALARIA.

scientific article

Efficient development of plasmodium liver stage-specific memory CD8+ T cells during the course of blood-stage malarial infection

scientific article published in December 2007

Efficient phagosomal maturation and degradation of Plasmodium-infected erythrocytes by dendritic cells and macrophages

scientific article published in June 2010

Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome

scientific article published on March 2010

First Nonphosphorylated Inhibitors of Phosphoglucose Isomerase Identified by Chemical Library Screening

HGF/MET signalling protects Plasmodium-infected host cells from apoptosis.

scientific article

Hepatocyte growth factor and its receptor are required for malaria infection

scientific article published on 12 October 2003

High throughput screening for anti-Trypanosoma cruzi drug discovery

scientific article (publication date: December 2014)

Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides

scientific article published on 22 August 2016

Identification of "Preferred" Human Kinase Inhibitors for Sleeping Sickness Lead Discovery. Are Some Kinases Better than Others for Inhibitor Repurposing?

scientific article published on 17 January 2016

Identification of small-molecule inhibitors of Trypansoma cruzi replication

scientific article

Identification of three classes of heteroaromatic compounds with activity against intracellular Trypanosoma cruzi by chemical library screening

scientific article

Imaging and identification of waterborne parasites using a chip-scale microscope

scientific article

Immuno-metabolic profile of human macrophages after Leishmania and Trypanosoma cruzi infection

scientific article published on 16 December 2019

Inhibiting the Plasmodium eIF2α Kinase PK4 Prevents Artemisinin-Induced Latency

scientific article published in December 2017

Inhibition of Plasmodium sporozoites infection by targeting the host cell

scientific article

Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.

scientific article published on March 2017

Interactions between dendritic cells and CD4+ T cells during Plasmodium infection.

scientific article

Invasion of mammalian host cells by Plasmodium sporozoites

scientific article

Is malarial anaemia homologous to neocytolysis after altitude acclimatisation?

scientific article published on 17 August 2013

Malaria and hypertension. Another co-evolutionary adaptation?

scientific article

Malaria blood stage suppression of liver stage immunity by dendritic cells

scientific article published on January 2003

Malaria inflammation by xanthine oxidase-produced reactive oxygen species

scientific article published on 02 July 2019

Malaria inhibits surface expression of complement receptor 1 in monocytes/macrophages, causing decreased immune complex internalization

scientific article published on 25 February 2013

Migration of Plasmodium sporozoites through cells before infection.

scientific article

Migration through host cells activates Plasmodium sporozoites for infection

scientific article published on 15 October 2002

Migration through host cells: the first steps of Plasmodium sporozoites in the mammalian host

scientific article

New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource.

scientific article

New pieces for the malaria liver stage puzzle: where will they fit?

scientific article

Novel 3-nitro-1H-1,2,4-triazole-based compounds as potential anti-Chagasic drugs: in vivo studies

scientific article published on October 2013

Optimization of physicochemical properties for 4-anilinoquinazoline inhibitors of trypanosome proliferation.

scientific article

Oxidative Stress Enhances Dendritic Cell Responses to Plasmodium falciparum

scientific article published on 05 November 2019

Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria

scientific article

Plasmodium DNA-mediated TLR9 activation of T-bet+ B cells contributes to autoimmune anaemia during malaria

scientific article published on 3 November 2017

Plasmodium falciparum-derived uric acid precipitates induce maturation of dendritic cells

scientific article

Plasmodium yoelii yoelii 17XNL constitutively expressing GFP throughout the life cycle

scientific article published on 17 October 2006

Plasmodium yoelii: Efficient in Vitro Invasion and Complete Development of Sporozoites in Mouse Hepatic Cell Lines

article

Plasmodium-induced inflammation by uric acid

scientific article

Potent antimalarial and transmission-blocking activities of centanamycin, a novel DNA-binding agent

scientific article published in February 2008

Prevalence of IgG Autoantibodies against GD3 Ganglioside in Acute Zika Virus Infection

scientific article published on 9 March 2018

Priming of CD8+ T cell responses following immunization with heat-killed Plasmodium sporozoites

scientific article published in May 2006

Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery.

scientific article published on 8 July 2015

Quantification of IgM molecular response by droplet digital PCR as a potential tool for the early diagnosis of sepsis.

scientific article

Replication attempt: "Effect of BMAP-28 antimicrobial peptides on Leishmania major promastigote and amastigote growth: role of leishmanolysin in parasite survival".

scientific article

Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery

scientific article published on May 2014

Role of TGF-beta and PGE2 in T cell responses during Plasmodium yoelii infection.

scientific article published in June 2007

Rupture and Release: A Role for Soluble Erythrocyte Content in the Pathology of Cerebral Malaria

scientific article published on 11 July 2017

Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells

scientific article published in October 1999

Series of Alkynyl-Substituted Thienopyrimidines as Inhibitors of Protozoan Parasite Proliferation

scientific article published on 04 September 2018

Small-molecule xenomycins inhibit all stages of the Plasmodium life cycle

scientific article

Structure-based approach to the identification of a novel group of selective glucosamine analogue inhibitors of Trypanosoma cruzi glucokinase

scientific article published on 14 January 2016

Tamoxifen activity against Plasmodium in vitro and in mice

scientific article published on 27 November 2019

Targeting Plasmodium host cells: survival within hepatocytes

scientific article published in October 2004

Targeting the Hexosamine Biosynthetic Pathway Prevents Developmental Cycle and Disease Pathology in Vertebrate Host

scientific article published on 28 February 2019

The High Blood Pressure-Malaria Protection Hypothesis

scientific article published on 22 September 2016

The myriad roles of cyclic AMP in microbial pathogens: from signal to sword

scientific article

The silent path to thousands of merozoites: the Plasmodium liver stage

scientific article published on November 2006

The susceptibility of trypanosomatid pathogens to PI3/mTOR kinase inhibitors affords a new opportunity for drug repurposing

scientific article

Transcriptome profile of dendritic cells during malaria: cAMP regulation of IL-6.

scientific article published on 23 February 2007

Transgenic parasites accelerate drug discovery

scientific article published on 23 January 2012

Uric acid is a mediator of the Plasmodium falciparum-induced inflammatory response

scientific article

Wide field-of-view Talbot grid-based microscopy for multicolor fluorescence imaging

scientific article published on June 2013

List of works by Ana Rodriguez

A Plasmodium yoelii soluble factor inhibits the phenotypic maturation of dendritic cells.

A high-efficiency microfluidic device for size-selective trapping and sorting

A potential role for plasma uric acid in the endothelial pathology of Plasmodium falciparum malaria

A putative kinase-related protein (PKRP) from Plasmodium berghei mediates infection in the midgut and salivary glands of the mosquito

A surprising role for uric acid: the inflammatory malaria response

Activity in vivo of anti-Trypanosoma cruzi compounds selected from a high throughput screening

Adenylyl cyclase alpha and cAMP signaling mediate Plasmodium sporozoite apical regulated exocytosis and hepatocyte infection.

Angiotensin II Moderately Decreases Plasmodium Infection and Experimental Cerebral Malaria in Mice

Angiotensin receptors and β-catenin regulate brain endothelial integrity in malaria

Anilinoquinoline based inhibitors of trypanosomatid proliferation

Anti-Self Phosphatidylserine Antibodies Recognize Uninfected Erythrocytes Promoting Malarial Anemia.

Anti-ganglioside antibodies in patients with Zika virus infection-associated Guillain-Barré Syndrome in Brazil

Antiparasitic Lead Discovery: Toward Optimization of a Chemotype with Activity Against Multiple Protozoan Parasites.

Antitrypanosomal Lead Discovery: Identification of a Ligand-Efficient Inhibitor of Trypanosoma cruzi CYP51 and Parasite Growth

Atypical activation of dendritic cells by Plasmodium falciparum

Atypical memory B-cells are associated with anemia through anti-phosphatidylserine antibodies

Autoantibody levels are associated with acute kidney injury, anemia and post-discharge morbidity and mortality in Ugandan children with severe malaria

Autoimmune Anemia in Malaria

Automated high-content assay for compounds selectively toxic to Trypanosoma cruzi in a myoblastic cell line

Chemical attenuation of Plasmodium berghei sporozoites induces sterile immunity in mice.

Chemically attenuated Plasmodium sporozoites induce specific immune responses, sterile immunity and cross-protection against heterologous challenge

Color capable sub-pixel resolving optofluidic microscope and its application to blood cell imaging for malaria diagnosis

Corrigendum to "Optimization of physicochemical properties for 4-Anilinoquinazoline inhibitors of trypanosome proliferation" [Eur. J. Med. Chem. 141 (2017) 446-459]

Daily Plasmodium yoelii infective mosquito bites do not generate protection or suppress previous immunity against the liver stage ⬇️

Dendritic cells can initiate protective immune responses against malaria.

Discovery and Optimization of a Compound Series Active against Trypanosoma cruzi, the Causative Agent of Chagas Disease

Divergent Roles of Antiself Antibodies during Infection

Diversity-oriented synthesis yields a new drug lead for treatment of chagas disease

Dual effect of Plasmodium-infected erythrocytes on dendritic cell maturation.

EVALUATION OF AROMATIC 6-SUBSTITUTED THIENOPYRIMIDINES AS SCAFFOLDS AGAINST PARASITES THAT CAUSE TRYPANOSOMIASIS, LEISHMANIASIS, AND MALARIA.

Efficient development of plasmodium liver stage-specific memory CD8+ T cells during the course of blood-stage malarial infection

Efficient phagosomal maturation and degradation of Plasmodium-infected erythrocytes by dendritic cells and macrophages

Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome

First Nonphosphorylated Inhibitors of Phosphoglucose Isomerase Identified by Chemical Library Screening

HGF/MET signalling protects Plasmodium-infected host cells from apoptosis.

Hepatocyte growth factor and its receptor are required for malaria infection

High throughput screening for anti-Trypanosoma cruzi drug discovery

Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides

Identification of "Preferred" Human Kinase Inhibitors for Sleeping Sickness Lead Discovery. Are Some Kinases Better than Others for Inhibitor Repurposing?

Identification of small-molecule inhibitors of Trypansoma cruzi replication

Identification of three classes of heteroaromatic compounds with activity against intracellular Trypanosoma cruzi by chemical library screening

Imaging and identification of waterborne parasites using a chip-scale microscope

Immuno-metabolic profile of human macrophages after Leishmania and Trypanosoma cruzi infection

Inhibiting the Plasmodium eIF2α Kinase PK4 Prevents Artemisinin-Induced Latency

Inhibition of Plasmodium sporozoites infection by targeting the host cell

Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.

Interactions between dendritic cells and CD4+ T cells during Plasmodium infection.

Invasion of mammalian host cells by Plasmodium sporozoites

Is malarial anaemia homologous to neocytolysis after altitude acclimatisation?

Malaria and hypertension. Another co-evolutionary adaptation?

Malaria blood stage suppression of liver stage immunity by dendritic cells

Malaria inflammation by xanthine oxidase-produced reactive oxygen species

Malaria inhibits surface expression of complement receptor 1 in monocytes/macrophages, causing decreased immune complex internalization

Migration of Plasmodium sporozoites through cells before infection.

Migration through host cells activates Plasmodium sporozoites for infection

Migration through host cells: the first steps of Plasmodium sporozoites in the mammalian host

New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource.

New pieces for the malaria liver stage puzzle: where will they fit?

Novel 3-nitro-1H-1,2,4-triazole-based compounds as potential anti-Chagasic drugs: in vivo studies

Optimization of physicochemical properties for 4-anilinoquinazoline inhibitors of trypanosome proliferation.

Oxidative Stress Enhances Dendritic Cell Responses to Plasmodium falciparum

Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria

Plasmodium DNA-mediated TLR9 activation of T-bet+ B cells contributes to autoimmune anaemia during malaria

Plasmodium falciparum-derived uric acid precipitates induce maturation of dendritic cells

Plasmodium yoelii yoelii 17XNL constitutively expressing GFP throughout the life cycle

Plasmodium yoelii: Efficient in Vitro Invasion and Complete Development of Sporozoites in Mouse Hepatic Cell Lines

Plasmodium-induced inflammation by uric acid

Potent antimalarial and transmission-blocking activities of centanamycin, a novel DNA-binding agent

Prevalence of IgG Autoantibodies against GD3 Ganglioside in Acute Zika Virus Infection

Priming of CD8+ T cell responses following immunization with heat-killed Plasmodium sporozoites

Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery.

Quantification of IgM molecular response by droplet digital PCR as a potential tool for the early diagnosis of sepsis.

Replication attempt: "Effect of BMAP-28 antimicrobial peptides on Leishmania major promastigote and amastigote growth: role of leishmanolysin in parasite survival".

Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery

Role of TGF-beta and PGE2 in T cell responses during Plasmodium yoelii infection.

Rupture and Release: A Role for Soluble Erythrocyte Content in the Pathology of Cerebral Malaria

Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells

Series of Alkynyl-Substituted Thienopyrimidines as Inhibitors of Protozoan Parasite Proliferation

Small-molecule xenomycins inhibit all stages of the Plasmodium life cycle