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List of works by Matthew R Groves

A Systematic Protein Refolding Screen Method using the DGR Approach Reveals that Time and Secondary TSA are Essential Variables

scientific article published on 24 August 2017

A fluorinated indole-based MDM2 antagonist selectively inhibits the growth of p53wt osteosarcoma cells

scientific article published on 16 February 2019

A unique Oct4 interface is crucial for reprogramming to pluripotency

scientific article

Acoustic Droplet Ejection Enabled Automated Reaction Scouting

scientific article published on 27 February 2019

Artificial Macrocycles as IL-17A/IL-17RA Antagonists

scientific article published on 25 October 2017

Aspartate aminotransferase: bridging carbohydrate and energy metabolism in Plasmodium falciparum.

scientific article published on March 2012

Benchmark of Generic Shapes for Macrocycles

scientific article published on 03 December 2020

Canonical signal recognition particle components can be bypassed for posttranslational protein targeting in chloroplasts

scientific article published on 18 May 2007

Crystallization and preliminary X-ray analysis of the Thermoplasma acidophilum 20S proteasome in complex with protein substrates

scientific article published on 30 September 2008

Crystallization and preliminary X-ray diffraction of malate dehydrogenase from Plasmodium falciparum.

scientific article published on 23 May 2012

Crystallization and preliminary characterization of a novel haem-binding protein of Streptomyces reticuli.

scientific article published on 05 April 2008

Crystallization of a Golgi-associated PR-1-related protein (GAPR-1) that localizes to lipid-enriched microdomains

scientific article published on 23 March 2004

Cytometric quantification of singlet oxygen in the human malaria parasite Plasmodium falciparum

scientific article published on 26 June 2012

Definition of domain boundaries and crystallization of the SMN Tudor domain

scientific article published on 23 January 2003

Dynamic substrate enhancement for the identification of specific, second-site-binding fragments targeting a set of protein tyrosine phosphatases.

scientific article published on 3 November 2011

Elucidation of haem-binding sites in the actinobacterial protein HbpS.

scientific article published on 21 February 2013

Engineering a Plant Polyketide Synthase for the Biosynthesis of Methylated Flavonoids

scientific article published in 2023

Fatty Acid- and Retinoid-binding Proteins Have Distinct Binding Pockets for the Two Types of Cargo

scientific article

High-resolution X-ray and NMR structures of the SMN Tudor domain: conformational variation in the binding site for symmetrically dimethylated arginine residues

scientific article (publication date: 21 March 2003)

Internal structure of an intact Convallaria majalis pollen grain observed with X-ray Fresnel coherent diffractive imaging

scientific article published in November 2012

Iron Binding at Specific Sites within the Octameric HbpS Protects Streptomycetes from Iron-Mediated Oxidative Stress

scientific article

Live and Let Dye: Visualizing the Cellular Compartments of the Malaria Parasite Plasmodium falciparum

scientific article published on 18 November 2019

Methods for protein characterization by mass spectrometry, thermal shift (ThermoFluor) assay, and multiangle or static light scattering

scientific article

Mobility of the conserved glycine 155 is required for formation of the active plasmodial Pdx1 dodecamer.

scientific article published on 9 March 2009

Molecular Target Validation of Aspartate Transcarbamoylase from Plasmodium falciparum by Torin 2

scientific article published on 12 March 2020

Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions

scientific article published on 06 February 2020

Novel redox-sensing modules: accessory protein- and nucleic acid-mediated signaling

scientific article published on 06 January 2012

Octameric alcohol oxidase dissociates into stable, soluble monomers upon incubation with dimethylsulfoxide

scientific article published on 23 January 2007

Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro

scientific article published on 25 April 2018

Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum

scientific article published on 28 February 2019

Protein engineering aspartic proteinases. Site-directed mutagenesis, biochemical characterisation, and X-ray analysis of chymosins with substituted single amino acid substitutions and loop replacements

scientific article published on January 1, 1998

Purification, crystallization and preliminary X-ray analysis of the aspartate aminotransferase of Plasmodium falciparum.

scientific article

Quantitive evaluation of macromolecular crystallization experiments using 1,8-ANS fluorescence

scientific article published on 10 July 2010

ROS-Mediated Signalling in Bacteria: Zinc-Containing Cys-X-X-Cys Redox Centres and Iron-Based Oxidative Stress

scientific article published on 29 September 2011

Rapid approach to complex boronic acids

scientific article published on 05 July 2019

Specific inhibition of the aspartate aminotransferase of Plasmodium falciparum

scientific article

Structural analysis of the human Golgi-associated plant pathogenesis related protein GAPR-1 implicates dimerization as a regulatory mechanism

scientific article

Structural basis for specificity of papain-like cysteine protease proregions toward their cognate enzymes ⬇️

scientific article published on September 1, 1998

Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex.

scientific article published on 27 December 2017

The (R)-enantiomer of the 6-chromanol derivate SUL-121 improves renal graft perfusion via antagonism of the α-adrenoceptor

scientific article published in Scientific Reports

The assembly of the plasmodial PLP synthase complex follows a defined course

scientific article

The vitamin B1 metabolism of Staphylococcus aureus is controlled at enzymatic and transcriptional levels

scientific article

Theory and applications of differential scanning fluorimetry in early-stage drug discovery

scientific article published on 31 January 2020

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