List of works - Hiroki Nagai

A C-terminal translocation signal required for Dot/Icm-dependent delivery of the Legionella RalF protein to host cells

scientific article

A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes

scientific article published on January 2002

A distinct segment of the sigma 32 polypeptide is involved in DnaK-mediated negative control of the heat shock response in Escherichia coli.

scientific article published in October 1994

Acanthamoeba S13WT relies on its bacterial endosymbiont to backpack human pathogenic bacteria and resist Legionella infection on solid media

scientific article published on 16 April 2018

Amoebal endosymbiont Neochlamydia genome sequence illuminates the bacterial role in the defense of the host amoebae against Legionella pneumophila

scientific article

Amoebal endosymbiont Neochlamydia protects host amoebae against Legionella pneumophila infection by preventing Legionella entry.

scientific article published on 6 January 2018

Bacterial Effector-Involved Temporal and Spatial Regulation by Hijack of the Host Ubiquitin Pathway ⬇️

scientific article published on 04 July 2011

Bacterial secretion system skews the fate of Legionella-containing vacuoles towards LC3-associated phagocytosis

scientific article published on 20 March 2017

Conformational switching of Escherichia coli RNA polymerase-promoter binary complex is facilitated by elongation factor GreA and GreB.

scientific article

Crystal Structure of Legionella DotD: Insights into the Relationship between Type IVB and Type II/III Secretion Systems

scientific article

Draft Genome Sequences of Legionella pneumophila JR32 and Lp01 Laboratory Strains Domesticated in Japan

scientific article published on 4 August 2016

Emerging insights into bacterial deubiquitinases

scientific article published on 02 November 2018

Functional domains of Escherichia coli single-stranded DNA binding protein as assessed by analyses of the deletion mutants.

scientific article

GroEL is involved in activation of Escherichia coli RNA polymerase devoid of the omega subunit in vivo

scientific article

Hijacking the Host Proteasome for the Temporal Degradation of Bacterial Effectors

scientific article published on 01 January 2014

Identification and functional characterization of K(+) transporters encoded by Legionella pneumophila kup genes.

scientific article published on 2 August 2013

Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth

scientific article published on 01 November 2000

Legionella RavZ Plays a Role in Preventing Ubiquitin Recruitment to Bacteria-Containing Vacuoles

scientific article published on 28 August 2017

Legionella metaeffector exploits host proteasome to temporally regulate cognate effector.

scientific article

Legionella translocates an E3 ubiquitin ligase that has multiple U-boxes with distinct functions

scientific journal article

LotA, a Legionella deubiquitinase, has dual catalytic activity and contributes to intracellular growth.

scientific article published on 15 March 2018

Microbially cleaved immunoglobulins are sensed by the innate immune receptor LILRA2

scientific article (publication date: 25 April 2016)

Modulation of the ubiquitination machinery by Legionella.

scientific article published on January 2013

Molecular and structural analysis of Legionella DotI gives insights into an inner membrane complex essential for type IV secretion.

scientific article

Native structure of a type IV secretion system core complex essential for Legionella pathogenesis

scientific article

Polymerase arrest at the lambdaP(R) promoter during transcription initiation

scientific article published on 01 April 2000

Protochlamydia induces apoptosis of human HEp-2 cells through mitochondrial dysfunction mediated by chlamydial protease-like activity factor

scientific article

Reduction in abortive transcription from the lambdaPR promoter by mutations in region 3 of the sigma70 subunit of Escherichia coli RNA polymerase

scientific article published in April 1998

Regions of the Escherichia coli primary sigma factor sigma70 that are involved in interaction with RNA polymerase core enzyme

scientific article published on 01 December 1997

Regulation of the heat shock response in E coli: involvement of positive and negative cis-acting elements in translation control of sigma 32 synthesis

scientific article published on 01 December 1991

Roles and regulation of the heat shock sigma factor sigma 32 in Escherichia coli.

scientific article published on October 1990

Show me the substrates: modulation of host cell function by type IV secretion systems.

scientific article

Subversion of Host Membrane Dynamics by the Legionella Dot/Icm Type IV Secretion System.

scientific article published in January 2017

Systematic sequencing of theEscherichia coligenome: analysis of the 0 – 2.4 min region ⬇️

scientific article published on July 11, 1992

The Type IVB secretion system: an enigmatic chimera

scientific article published on 31 October 2015

The machinery at endoplasmic reticulum-plasma membrane contact sites contributes to spatial regulation of multiple Legionella effector proteins

scientific article

The structure of RalF, an ADP-ribosylation factor guanine nucleotide exchange factor from Legionella pneumophila, reveals the presence of a cap over the active site

scientific article published in November 2004

Type IVB Secretion Systems of Legionella and Other Gram-Negative Bacteria.

scientific article published on 27 June 2011

List of works by Hiroki Nagai

A C-terminal translocation signal required for Dot/Icm-dependent delivery of the Legionella RalF protein to host cells

A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes

A distinct segment of the sigma 32 polypeptide is involved in DnaK-mediated negative control of the heat shock response in Escherichia coli.

Acanthamoeba S13WT relies on its bacterial endosymbiont to backpack human pathogenic bacteria and resist Legionella infection on solid media

Amoebal endosymbiont Neochlamydia genome sequence illuminates the bacterial role in the defense of the host amoebae against Legionella pneumophila

Amoebal endosymbiont Neochlamydia protects host amoebae against Legionella pneumophila infection by preventing Legionella entry.

Bacterial Effector-Involved Temporal and Spatial Regulation by Hijack of the Host Ubiquitin Pathway ⬇️

Bacterial secretion system skews the fate of Legionella-containing vacuoles towards LC3-associated phagocytosis

Conformational switching of Escherichia coli RNA polymerase-promoter binary complex is facilitated by elongation factor GreA and GreB.

Crystal Structure of Legionella DotD: Insights into the Relationship between Type IVB and Type II/III Secretion Systems

Draft Genome Sequences of Legionella pneumophila JR32 and Lp01 Laboratory Strains Domesticated in Japan

Emerging insights into bacterial deubiquitinases

Functional domains of Escherichia coli single-stranded DNA binding protein as assessed by analyses of the deletion mutants.

GroEL is involved in activation of Escherichia coli RNA polymerase devoid of the omega subunit in vivo

Hijacking the Host Proteasome for the Temporal Degradation of Bacterial Effectors

Identification and functional characterization of K(+) transporters encoded by Legionella pneumophila kup genes.

Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth

Legionella RavZ Plays a Role in Preventing Ubiquitin Recruitment to Bacteria-Containing Vacuoles

Legionella metaeffector exploits host proteasome to temporally regulate cognate effector.

Legionella translocates an E3 ubiquitin ligase that has multiple U-boxes with distinct functions

LotA, a Legionella deubiquitinase, has dual catalytic activity and contributes to intracellular growth.

Microbially cleaved immunoglobulins are sensed by the innate immune receptor LILRA2

Modulation of the ubiquitination machinery by Legionella.

Molecular and structural analysis of Legionella DotI gives insights into an inner membrane complex essential for type IV secretion.

Native structure of a type IV secretion system core complex essential for Legionella pathogenesis

Polymerase arrest at the lambdaP(R) promoter during transcription initiation

Protochlamydia induces apoptosis of human HEp-2 cells through mitochondrial dysfunction mediated by chlamydial protease-like activity factor

Reduction in abortive transcription from the lambdaPR promoter by mutations in region 3 of the sigma70 subunit of Escherichia coli RNA polymerase

Regions of the Escherichia coli primary sigma factor sigma70 that are involved in interaction with RNA polymerase core enzyme

Regulation of the heat shock response in E coli: involvement of positive and negative cis-acting elements in translation control of sigma 32 synthesis

Roles and regulation of the heat shock sigma factor sigma 32 in Escherichia coli.

Show me the substrates: modulation of host cell function by type IV secretion systems.

Subversion of Host Membrane Dynamics by the Legionella Dot/Icm Type IV Secretion System.

Systematic sequencing of theEscherichia coligenome: analysis of the 0 – 2.4 min region ⬇️

The Type IVB secretion system: an enigmatic chimera

The machinery at endoplasmic reticulum-plasma membrane contact sites contributes to spatial regulation of multiple Legionella effector proteins

The structure of RalF, an ADP-ribosylation factor guanine nucleotide exchange factor from Legionella pneumophila, reveals the presence of a cap over the active site

Type IVB Secretion Systems of Legionella and Other Gram-Negative Bacteria.