Search filters

List of works by Markus M Lerch

100 years of German Society for Digestive and Metabolic Diseases (DGVS) and 50 years of Journal of Gastroenterology ⬇️

scientific article published on April 12, 2013

50 years of progress in pathophysiology, diagnosis and treatment of chronic pancreatitis ⬇️

scientific article published on April 12, 2013

A Syngeneic Orthotopic Murine Model of Pancreatic Adenocarcinoma in the C57/BL6 Mouse Using the Panc02 and 6606PDA Cell Lines ⬇️

scientific article published on June 30, 2011

A circus flea

scientific article published in February 1997

A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis

scientific article

A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

scientific article published on 19 October 2015

A new technique for endoscopic implantation and explantation of large-bore biliary endoprostheses in patients with non-surgical common bile duct obstruction

scientific article published in September 1987

A plasma protease which is expressed during supramaximal stimulation causes in vitro subcellular redistribution of lysosomal enzymes in rat exocrine pancreas.

scientific article

A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis

scientific article published on 16 March 2015

A structured weight loss program increases gut microbiota phylogenetic diversity and reduces levels of Collinsella in obese type 2 diabetics: A pilot study

scientific article published on 18 July 2019

A unique pancreatic mitochondrial response to calcium and its role in apoptosis

scientific article published on 01 March 2009

ABO blood type B and fucosyltransferase 2 non-secretor status as genetic risk factors for chronic pancreatitis

article published in 2015

Absence of association between SPINK1 trypsin inhibitor mutations and Type 1 or 2 diabetes mellitus in India and Germany

scientific article published on 01 November 2003

Absence of the neutrophil serine protease cathepsin G decreases neutrophil granulocyte infiltration but does not change the severity of acute pancreatitis

scientific article published on 14 November 2019

Accuracy of ultrasonography in the assessment of liver fat compared with MRI

scientific article published on 05 April 2019

Acute Pancreatitis-Progress and Challenges: A Report on an International Symposium

scientific article

Acute necrotizing pancreatitis in the opossum: earliest morphological changes involve acinar cells

scientific article published in July 1992

Acute pancreatitis

scientific article published on 01 October 1994

Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: a randomized controlled trial

scientific article

Advances in the etiology of chronic pancreatitis.

scientific article published on September 2010

Alcohol disrupts levels and function of the cystic fibrosis transmembrane conductance regulator to promote development of pancreatitis.

scientific article

An extraordinary Dieulafoy's lesion presenting as varices of the gastric fundus

scientific article published on 01 December 2001

Anal sphincter function after intersphincteric resection and stapled ileal pouch-anal anastomosis

scientific article published in January 1991

Anatomic variants of the pancreatic duct and their clinical relevance: an MR-guided study in the general population

scientific article published on 15 August 2014

Angiopoietin-2, a regulator of vascular permeability in inflammation, is associated with persistent organ failure in patients with acute pancreatitis from the United States and Germany

scientific article published on 11 May 2010

Animal models for investigating chronic pancreatitis.

scientific article published on December 2011

Anticipating disaster: the genetics of familial pancreatic cancer

scientific article published on February 2006

Association analysis of genetic variants in the myosin IXB gene in acute pancreatitis

scientific article

Association between Serum Thyroid-Stimulating Hormone Levels and Visceral Adipose Tissue: A Population-Based Study in Northeast Germany

scientific article published on 8 November 2016

Association of Human Protein-tyrosine Phosphatase κ with Members of the Armadillo Family

scientific article published in Journal of Biological Chemistry

Association of non-alcoholic fatty liver disease with chronic kidney disease: a systematic review and meta-analysis

scientific article

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Associations of circulating chemerin and adiponectin concentrations with hepatic steatosis

scientific article published on 01 August 2019

Autoantibodies against the exocrine pancreas in autoimmune pancreatitis: gene and protein expression profiling and immunoassays identify pancreatic enzymes as a major target of the inflammatory process.

scientific article

Autoimmune pancreatitis

scientific article published in June 2007

Autoimmune pancreatitis in MRL/Mp mice is a T cell-mediated disease responsive to cyclosporine A and rapamycin treatment

article

Balance of expression of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in chronic pancreatitis

article

Bedside ultrasound in decision making for emergency surgery: its role in medical intensive care patients

scientific article

Behandlung der schweren chronischen Obstipation: Differentielle Rollen konventioneller Laxantien und des Prokinetikums Prucaloprid

Breaking down haem attenuates acute pancreatitis: a new treatment option?

scientific article published on 11 February 2011

CCK-JMV-180, an analog of cholecystokinin, releases intracellular calcium from an inositol trisphosphate-independent pool in rat pancreatic acini

scientific article published on 01 June 1992

CEA response is associated with tumor response and survival in patients with KRAS exon 2 wild-type and extended RAS wild-type metastatic colorectal cancer receiving first-line FOLFIRI plus cetuximab or bevacizumab (FIRE-3 trial).

scientific article published on 27 May 2016

COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer.

scientific article

Calcium-magnesium interactions in pancreatic acinar cells

scientific article published on March 2001

Carrying asymptomatic gallstones is not associated with changes in intestinal microbiota composition and diversity but cholecystectomy with significant dysbiosis

scientific article published on 23 March 2021

Cathepsin B Activity Initiates Apoptosis via Digestive Protease Activation in Pancreatic Acinar Cells and Experimental Pancreatitis.

scientific article published on 12 May 2016

Cathepsin B gene polymorphism Val26 is not associated with idiopathic chronic pancreatitis in European patients

scientific article published on September 2007

Cathepsin B promotes the progression of pancreatic ductal adenocarcinoma in mice

scientific article published on 09 December 2011

Cathepsin B-mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice.

scientific article published on 24 October 2017

Cathepsin D regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis.

scientific article published on 11 December 2017

Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice.

scientific article published on 10 November 2009

Cellular Redistribution of Protein Tyrosine Phosphatases LAR and PTPσ by Inducible Proteolytic Processing ⬇️

scientific article published on August 11, 1997

Characterization of PCP-2, a novel receptor protein tyrosine phosphatase of the MAM domain family

scientific article

Characterization of a non-invasive, vascular model of acute necrotizing pancreatitis

scientific article published on 01 January 1996

Chronic Pancreatitis in the 21st Century - Research Challenges and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop

scientific article published on November 2016

Chronic pancreatitis

scientific article published on 7 September 2017

Chronic pancreatitis as a risk factor for the development of pancreatic cancer--diagnostic challenges

scientific article published in April 2010

Chronic pancreatitis: an update on genetic risk factors

scientific article published on 01 September 2018

Chronic stress increases experimental pancreatic cancer growth, reduces survival and can be antagonised by beta-adrenergic receptor blockade.

scientific article published on 23 March 2016

Cigarette Smoking as a Risk Factor for Pancreatic Cancer in Patients With Hereditary Pancreatitis

scientific article published in The Journal of the American Medical Association

Circulating Angiopoietin-2 and Its Soluble Receptor Tie-2 Concentrations Are Related to Renal Function in Two Population-Based Cohorts

scientific article

Circulating U2 small nuclear RNA fragments as a novel diagnostic biomarker for pancreatic and colorectal adenocarcinoma

scientific article published on 14 September 2012

Circulating angiopoietin-2 and its soluble receptor Tie-2 concentrations are related to inflammatory markers in the general population

scientific article published on 7 February 2018

Classifying an unpredictable disease: the revised Atlanta classification of acute pancreatitis ⬇️

scientific article published on January 1, 2013

Clinical Profile of Autoimmune Pancreatitis and Its Histological Subtypes

scientific article published on 01 August 2011

Clinical and genetic characteristics of hereditary pancreatitis in Europe

scientific article (publication date: March 2004)

Clinical characterization of patients with hereditary pancreatitis and mutations in the cationic trypsinogen gene

scientific article published on 01 December 2001

Clinical perspectives in pancreatology: compliance with acute pancreatitis guidelines in Germany

scientific article published on 16 August 2005

Cloning, characterization, and differential expression of MDK2 and MDK5, two novel receptor tyrosine kinases of the eck/eph family.

scientific article published in November 1995

Cohort Profile: The Study of Health in Pomerania

article

Cohort profile: Greifswald approach to individualized medicine (GANI_MED)

scientific article

Common adult stem cells in the human breast give rise to glandular and myoepithelial cell lineages: a new cell biological concept

scientific article published on June 2002

Common biliary-pancreatic conduit stenosis induces pancreobiliary reflux

scientific article published on 01 January 1997

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

scientific article

Common variants in glyoxalase I do not increase chronic pancreatitis risk

scientific article published on 29 October 2019

Common variants in the CLDN2 - MORC4 and PRSS1 - PRSS2 loci confer susceptibility to acute pancreatitis

scientific article published on 01 June 2018

Comparability of size measurements of the pancreas in magnetic resonance imaging and transabdominal ultrasound

scientific article published on 07 January 2020

Complement Component 5 Mediates Development of Fibrosis, via Activation of Stellate Cells, in 2 Mouse Models of Chronic Pancreatitis

scientific article

Comprehensive metabolic profiling of chronic low-grade inflammation among generally healthy individuals

scientific article published on 30 November 2017

Concordance of indirect methods for the detection of lactose malabsorption in diabetic and nondiabetic subjects

scientific article published on January 1991

Conservative treatment of acute pancreatitis

scientific article

Copy number variants and VNTR length polymorphisms of the carboxyl-ester lipase (CEL) gene as risk factors in pancreatic cancer

scientific article published on 11 October 2016

Copy number variants in lipid metabolism genes are associated with gallstones disease in men

scientific article published on 04 September 2019

Correspondence (reply): In Reply

Cost assessment for endoscopic procedures in the German diagnosis-related-group (DRG) system - 5 year cost data analysis of the German Society of Gastroenterology project

scientific article

Course of illness in acute pancreatitis

scientific article published in January 2001

Current management of acute pancreatitis

scientific article published on 01 October 2005

Cutting Edge: Protein Arginine Deiminase 2 and 4 Regulate NLRP3 Inflammasome-Dependent IL-1β Maturation and ASC Speck Formation in Macrophages

scientific article published on 10 July 2019

Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome)

scientific article

Deficiency of cathepsin C ameliorates severity of acute pancreatitis by reduction of neutrophil elastase activation and cleavage of E-cadherin

scientific article published on 19 November 2018

Defining chronic pancreatitis with a focus on pathological stress responses.

scientific article

Delayed severe bleeding complications after treatment of pancreatic fluid collections with lumen-apposing metal stents

scientific article published on 12 January 2017

Determination of the Pathological Features of NPC1 Variants in a Cellular Complementation Test

scientific article published on 19 October 2019

Development and Validation of a Chronic Pancreatitis Prognosis Score in 2 Independent cohorts

scientific article published on 14 September 2017

Development of Pancreatic Cancer: Targets for Early Detection and Treatment.

scientific article published on 22 June 2016

Development of a telemedical monitoring concept for the care of malnourished geriatric home-dwelling patients: a pilot study

scientific article published on 21 March 2012

Development of gastrointestinal infectious diseases between 2000 and 2012

scientific article

Development, external validation, and comparative assessment of a new diagnostic score for hepatic steatosis

scientific article published on 24 June 2014

Developmental and metabolic disorders of the pancreas

scientific article

Diagnosis and treatment of acute pancreatitis: are the guidelines accepted?

scientific article published in July 2005

Diagnosis and treatment of pancreatic pseudocysts in chronic pancreatitis

scientific article

Diagnostic value of indirect pancreatic function test in serum of anuric patients with chronic renal failure

scientific article published on 01 May 1994

Differential expression of heat shock proteins in pancreatic carcinoma

scientific article (publication date: 15 January 1994)

Differential roles of inflammatory cells in pancreatitis.

scientific article published on March 2012

Digestive enzyme expression in the large intestine of children with short bowel syndrome in a late stage of adaptation

scientific article published on 19 January 2020

Direct detection of premature protease activation in living pancreatic acinar cells

scientific article published on 01 June 1998

Disassembly of rat pancreatic acinar cell cytoskeleton during supramaximal secretagogue stimulation

scientific article published on 01 February 1995

Disentangling the genetics of lean mass

article

Disposition and antimuscarinic effects of the urinary bladder spasmolytics propiverine: influence of dosage forms and circadian-time rhythms.

scientific article

Dissociation and reassembly of adherens junctions during experimental acute pancreatitis

scientific article published on 01 October 1997

Do Animal Models of Acute Pancreatitis Reproduce Human Disease?

scientific article

Do Genetic Markers of Inflammation Modify the Relationship between Periodontitis and Nonalcoholic Fatty Liver Disease? Findings from the SHIP Study

scientific article published on July 2017

Does the hospital cost of care differ for inflammatory bowel disease patients with or without gastrointestinal infections? A case-control study

scientific article published on 15 July 2014

Drug efflux transporter multidrug resistance-associated protein 5 affects sensitivity of pancreatic cancer cell lines to the nucleoside anticancer drug 5-fluorouracil

scientific article published on 7 October 2010

Drug induced pancreatitis.

scientific article published on April 2010

Drug-induced pancreatitis.

scientific article published on April 2012

EUS-guided Trucut needle biopsies as first-line diagnostic method for patients with intestinal or extraintestinal mass lesions

scientific article published on 05 March 2009

Early Parenteral Nutrition in Patients with Biliopancreatic Mass Lesions, a Prospective, Randomized Intervention Trial

scientific article

Early changes in pancreatic acinar cell calcium signaling after pancreatic duct obstruction

scientific article

Early detection of sporadic pancreatic cancer: summative review

scientific article

Early ductal decompression prevents the progression of biliary pancreatitis: an experimental study in the opossum

scientific article published on 01 July 1993

Early events in acute pancreatitis

scientific article published on 01 March 2005

Early events in acute pancreatitis.

scientific article

Early trypsin activation develops independently of autophagy in caerulein-induced pancreatitis in mice

scientific article published on 30 July 2019

Early trypsinogen activation in acute pancreatitis.

scientific article published in May 2000

Economic aspects of inpatient treatment for decompensated liver cirrhosis: a prospective study employing an evidence-based clinical pathway

scientific article published on 8 January 2013

Effect of adjuvant chemotherapy with fluorouracil plus folinic acid or gemcitabine vs observation on survival in patients with resected periampullary adenocarcinoma: the ESPAC-3 periampullary cancer randomized trial

scientific article

Effect of hyperthermia on premature intracellular trypsinogen activation in the exocrine pancreas

scientific article published on 01 March 2001

Effect of kinin inhibition in experimental acute pancreatitis

scientific article published on 01 October 1995

Effect of magnesium supplementation and depletion on the onset and course of acute experimental pancreatitis

scientific article published on 25 November 2013

Effect of oral administration of AZD8309, a CXCR2 antagonist, on the severity of experimental pancreatitis

scientific article published on 14 July 2016

Effective treatment of benign biliary strictures with a removable, fully covered, self-expandable metal stent: A prospective, multicenter European study

scientific article

Effects of chloroquine and methylamine on lysosomal enzyme secretion by rat pancreas

scientific article published on March 1992

Effects of growth hormone treatment on B-type natriuretic peptide as a marker of heart failure in adults with growth hormone deficiency

scientific article published in October 2006

Efficacy of gemcitabine plus erlotinib in rash-positive patients with metastatic pancreatic cancer selected according to eligibility for FOLFIRINOX: A prospective phase II study of the 'Arbeitsgemeinschaft Internistische Onkologie'.

scientific article published on 14 March 2018

Endocytotic segregation of gliadin peptide 31-49 in enterocytes

scientific article published on 03 August 2009

Endoscopic management of complications of acute pancreatitis: an update on the field

scientific article published on 25 October 2018

Endoscopic sphincterotoMy for delayIng choLecystectomy in mild acute biliarY pancreatitis (EMILY study): protocol of a multicentre randomised clinical trial

scientific article published on 09 July 2019

Endowashers: an overlooked risk for possible post-endoscopic infections

scientific article published on 15 December 2011

English language version of the S3-consensus guidelines on chronic pancreatitis: Definition, aetiology, diagnostic examinations, medical, endoscopic and surgical management of chronic pancreatitis

scientific article published on 14 December 2015

Enhancement of pancreas and diagnosis of pancreatitis using manganese dipyridoxyl diphosphate

scientific article published on 01 June 1994

Enhancement of transforming growth factor β1 expression in the rat pancreas during regeneration from caerulein-induced pancreatitis

scientific article published on 01 October 1994

Environmental risk factors for chronic pancreatitis and pancreatic cancer.

scientific article published on 05 July 2011

Erratum: COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer

article

Erratum: Corrigendum: Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome)

scholarly article published in Nature Genetics

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article

Etiology and Risk Factors of Acute and Chronic Pancreatitis

scientific article published on 13 March 2019

Evaluation of a non-invasive multisensor accelerometer for calculating energy expenditure in ventilated intensive care patients compared to indirect calorimetry and predictive equations.

scientific article published on 14 September 2016

Evaluation of genome-wide loci of iron metabolism in hereditary hemochromatosis identifies PCSK7 as a host risk factor of liver cirrhosis

scientific article published on 20 February 2014

Exocrine Pancreatic Function Modulates Plasma Metabolites Through Changes in Gut Microbiota Composition

scientific article published on 01 April 2021

Experimental animal models of acute pancreatitis

scientific article published on June 1994

Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer.

scientific article published in August 1995

Expression of the protooncogene jun is induced in the rat pancreas by cerulein infusion

scientific article published on 01 August 1997

Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis

scientific article

Extracellular cleavage of E-cadherin by leukocyte elastase during acute experimental pancreatitis in rats

scientific article published in October 2005

Extracellular matrix stimulates reactive oxygen species production and increases pancreatic cancer cell survival through 5-lipoxygenase and NADPH oxidase

scientific article published on 21 July 2005

FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab for metastatic colorectal cancer (FIRE-3): a post-hoc analysis of tumour dynamics in the final RAS wild-type subgroup of this randomised open-label phase 3 trial

scientific article

Factors That Affect Prevalence of Small Intestinal Bacterial Overgrowth in Chronic Pancreatitis: A Systematic Review, Meta-Analysis, and Meta-Regression

scientific article published on 01 September 2019

Failure of a prolyl 4-hydroxylase inhibitor to alter extracellular matrix deposition during experimental pancreatitis

scientific article published on 01 January 1997

Fecal Microbiota Transplant in Patients With Recurrent Clostridium Difficile Infection.

scientific article

Focal pancreatic lesions in autoimmune pancreatitis and weight loss

scientific article published on 22 July 2020

Fucosyltransferase 2 (FUT2) non-secretor status and blood group B are associated with elevated serum lipase activity in asymptomatic subjects, and an increased risk for chronic pancreatitis: a genetic association study

Fulminant liver failure after administration of the herbal antidepressant Kava-Kava

scientific article

Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration

scientific article published on 13 May 2021

Functional abdominal pain and discomfort (IBS) is not associated with faecal microbiota composition in the general population

article

Functional characterisation of the CFTR mutations M348V and A1087P from patients with pancreatitis suggests functional interaction between CFTR monomers

scientific article published in May 2009

Gallstone pancreatitis: when is endoscopic retrograde cholangiopancreatography truly necessary?

scientific article

Gallstones and acute pancreatitis--mechanisms and mechanics

scientific article published on July 1994

Gastrobronchial reflux in patients on artificial ventilation and antacid therapy

scientific article published on 01 January 1989

Gastrointestinal Stromal Tumors: Clinical Symptoms, Location, Metastasis Formation, and Associated Malignancies in a Single Center Retrospective Study

scientific article published on 05 June 2018

Gene conversion between cationic trypsinogen (PRSS1) and the pseudogene trypsinogen 6 (PRSS3P2) in patients with chronic pancreatitis

scientific article

Genetic and functional identification of the likely causative variant for cholesterol gallstone disease at the ABCG5/8 lithogenic locus

scientific article published on 25 January 2013

Genetic aspects of chronic pancreatitis

scientific article published in September 2001

Genetic basis and pancreatic biology of Johanson-Blizzard syndrome

scientific article

Genetic polymorphisms in the UDP-glucuronosyltransferase UGT1A7 gene in patients with acute liver failure after kava-kava consumption

scientific article

Genetic susceptibility factors for alcohol-induced chronic pancreatitis.

scientific article published on 18 June 2015

Genetic testing for hereditary pancreatitis: guidelines for indications, counselling, consent and privacy issues.

scientific article

Genetic variants associated with susceptibility to Helicobacter pylori--reply

scientific article published in September 2013

Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians

article

Genetics, Cell Biology, and Pathophysiology of Pancreatitis

scientific article published on 18 January 2019

Genome-Wide Association Study Identifies Variants Associated With Autoimmune Hepatitis Type 1

article

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis

scientific article

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

scientific article published on 16 October 2011

Geriatric nutritional risk index correlates with length of hospital stay and inflammatory markers in older inpatients.

scientific article published on 9 July 2016

German Society of Gastroenterology, Digestive and Metabolic Diseases (DGVS) position statement on endoscopic decompression in acute Ileus

scientific article published on 6 December 2017

Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma

scientific article published on 01 January 2007

Helicobacter pylori infection associates with fecal microbiota composition and diversity

scientific article published on 27 December 2019

Hepatic Steatosis Is Associated With Adverse Molecular Signatures in Subjects Without Diabetes

scientific article published on 01 October 2018

Hepatic effects of thoracic epidural analgesia in experimental severe acute pancreatitis.

scientific article published in December 2009

Hepatic steatosis is associated with low serum testosterone and high serum DHEAS levels in men.

scientific article published on 10 February 2009

Hepatocyte microchimerism in human liver transplant after stem cell mobilization

scientific article published on 01 February 2008

Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122 --> Cys) that alters autoactivation and autodegradation of cationic trypsinogen

scientific article published on 21 November 2001

Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: a novel disease mechanism

scientific article

Hereditäre Pankreatitis

scientific article published on 01 October 2006

High versus low energy administration in the early phase of acute pancreatitis (GOULASH trial): protocol of a multicentre randomised double-blind clinical trial.

scientific article published on 14 September 2017

Histopathologic and clinical subtypes of autoimmune pancreatitis: the Honolulu consensus document

scientific article published on July 2010

Histopathologic and clinical subtypes of autoimmune pancreatitis: the honolulu consensus document.

scientific article published on January 2010

Human pancreatitis and the role of cathepsin B.

scientific article published on September 2006

Identification of genetic loci associated with Helicobacter pylori serologic status

scientific article published in May 2013

IgG4-related disease: a new kid on the block or an old aquaintance?

scientific article

Immune Cell and Stromal Signature Associated With Progression-Free Survival of Patients With Resected Pancreatic Ductal Adenocarcinoma

scientific article published on 06 August 2018

Impaired Exocrine Pancreatic Function Associates With Changes in Intestinal Microbiota Composition and Diversity

article

In reply

In vitro perfusion and incubation of rat pancreatic lobules in a kinetic system

scientific article published on January 1, 1991

In vivo and in vitro effects of the azidothymidine analog dideoxyinosine on the exocrine pancreas of the rat

scientific article published on 01 July 1992

In vivo imaging of pancreatic tumours and liver metastases using 7 Tesla MRI in a murine orthotopic pancreatic cancer model and a liver metastases model

scientific article

Incidence of pancreatitis and pancreatic cancer in a randomized controlled multicenter trial (SAVOR-TIMI 53) of the dipeptidyl peptidase-4 inhibitor saxagliptin

scientific article published on 09 June 2014

Independent risk factors for gallstone formation in a region with high cholelithiasis prevalence

scientific article

Infection of an intravenous port system with Metschnikowia pulcherrima Pitt et Miller

scientific article published in November 1998

International Consensus Guidance Statement on the Management and Treatment of IgG4-Related Disease

scientific article (publication date: 26 June 2015)

International consensus diagnostic criteria for autoimmune pancreatitis: guidelines of the International Association of Pancreatology

scientific article published in April 2011

International consensus for the treatment of autoimmune pancreatitis

scientific article published on 12 December 2016

International consensus statements on early chronic Pancreatitis. Recommendations from the working group for the international consensus guidelines for chronic pancreatitis in collaboration with The International Association of Pancreatology, America

scientific article published on 21 May 2018

Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats ⬇️

scientific article published on 01 August 1998

Intraductal papillary mucinous neoplasia: which findings support observation?

scientific article published in February 2012

Inverse association between serum free thyroxine levels and hepatic steatosis: results from the Study of Health in Pomerania

scientific article

Inverted upper gastrointestinal endoscope in the esophagus: technique of endoscopic straightening with an auxiliary instrument

scientific article published on November 1990

Investigation of the colorectal cancer susceptibility region on chromosome 8q24.21 in a large German case-control sample

article

Irritable bowel syndrome, mental health, and quality of life: Data from a population-based survey in Germany (SHIP-Trend-0)

scientific article published on 15 November 2018

Is hepatic steatosis associated with left ventricular mass index increase in the general population?

scientific article

Known risk factors do not explain disparities in gallstone prevalence between Denmark and northeast Germany

scientific article

LIFEStyle, Prevention and Risk of Acute PaNcreatitis (LIFESPAN): protocol of a multicentre and multinational observational case-control study

scientific article published on 06 January 2020

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article

Liposome mediated in vivo gene transfer into different tissues of the gastrointestinal tract

scientific article published on 01 December 1994

Liver injury and genetic polymorphisms in the cytochrome P450 and UDP-glucuronosyltransferase genes

scientific article published on 15 December 2015

Local clustering of PRSS1 R122H mutations in hereditary pancreatitis patients from Northern Germany

scientific article published on 8 August 2008

Loci From a Genome-Wide Analysis of Bilirubin Levels Are Associated With Gallstone Risk and Composition

article

Long-term impairment of adrenal function after unilateral adrenalectomy

scientific article published on 01 March 1993

Long-term instability of the intestinal microbiome is associated with metabolic liver disease, low microbiota diversity, diabetes mellitus and impaired exocrine pancreatic function

scientific article published on 09 November 2020

Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis

scientific article published on 11 December 2012

Lymphocyte apoptosis after exhaustive and moderate exercise

scientific article

MARS (Molecular Adsorbent Recycling System) as a novel hepatic detoxification procedure until orthotopic liver transplantation

scientific article published on December 2001

Magnetic Resonance Imaging of Changes in Abdominal Compartments in Obese Diabetics during a Low-Calorie Weight-Loss Program

scientific article

Maternal inheritance pattern of hereditary pancreatitis in patients with pancreatic carcinoma

scientific article published on 01 April 1999

Metabolic biomarker signature to differentiate pancreatic ductal adenocarcinoma from chronic pancreatitis.

scientific article published on 20 January 2017

Metastatic behaviour of primary human tumours in a zebrafish xenotransplantation model

scientific article

Methodenreport zur S3-Leitlinie Chronische Pankreatitis: Definition, Ätiologie, Diagnostik und konservative, interventionell endoskopische und operative Therapie der chronischen Pankreatitis

MiR-502 is the first reported miRNA simultaneously targeting two components of the classical non-homologous end joining (C-NHEJ) in pancreatic cell lines

scientific article published on 18 January 2020

Missorting of cathepsin B into the secretory compartment of CI-MPR/IGFII-deficient mice does not induce spontaneous trypsinogen activation but leads to enhanced trypsin activity during experimental pancreatitis--without affecting disease severity.

scientific article published on October 2010

Mnk1 is a novel acinar cell-specific kinase required for exocrine pancreatic secretion and response to pancreatitis in mice.

scientific article published on 18 July 2014

Models of acute and chronic pancreatitis.

scientific article published on June 2013

Modified intra-arterial calcium stimulation with venous sampling test for preoperative localization of insulinomas

scientific article published in May 1998

Molecular Mechanism Contributing to Malnutrition and Sarcopenia in Patients with Liver Cirrhosis

scientific article published on 28 July 2020

Mortality is associated with inflammation, anemia, specific diseases and treatments, and molecular markers

scientific article

Mutations in the human UBR1 gene and the associated phenotypic spectrum

scientific article published on 09 April 2014

NLRP3 Inflammasome Regulates Development of Systemic Inflammatory Response and Compensatory Anti-Inflammatory Response Syndromes in Mice With Acute Pancreatitis

scientific article published on 05 October 2019

Natural History and Management of Intraductal Papillary Mucinous Neoplasms: Current Evidence

scientific article

Necrosis, Apoptosis, Necroptosis, Pyroptosis: It Matters How Acinar Cells Die During Pancreatitis.

scientific article published on 31 May 2016

Needle knife precut-induced bleeding from a "pancreatic cyst"

scientific article published on 01 October 2000

Newcastle disease virus mediates pancreatic tumor rejection via NK cell activation and prevents cancer relapse by prompting adaptive immunity.

scientific article published on 31 August 2017

Next generation sequencing pitfalls in diagnosing trypsinogen (PRSS1) mutations in chronic pancreatitis

scientific article published on 28 September 2020

No more intravenous procaine for pancreatitis pain?

scientific article published on 30 January 2004

Noninvasive quantification of hepatic fat content using three-echo dixon magnetic resonance imaging with correction for T2* relaxation effects

scientific article published in December 2011

Nutrition in Pancreatic Cancer: A Review

scientific article

Nutritional management of chronic pancreatitis: A systematic review and meta-analysis of randomized controlled trials

scientific article published on 30 August 2020

Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition

scientific article published on 06 August 2019

Observational longitudinal multicentre investigation of acute pancreatitis (GOULASH PLUS): follow-up of the GOULASH study, protocol

scientific article published on 03 September 2019

Optimal timing of oral refeeding in mild acute pancreatitis: results of an open randomized multicenter trial.

scientific article

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

scientific article published on 28 November 2016

PD-027BRAF mutant and RAS mutant patients treated with FOLFIRI plus Bevacizumab or FOLFIRI plus Cetuximab. Role of ETS and molecular markers in FIRE-3 (AIO KRK-0306).

scientific article published on 21 June 2016

Palliative transhepatic biliary drainage and enteral nutrition

scientific article published on 01 December 1999

Pancreatic Exocrine Insufficiency as a Complication of Gastrointestinal Surgery and the Impact of Pancreatic Enzyme Replacement Therapy

scientific article published on 16 August 2019

Pancreatic Steatosis Is Associated With Impaired Exocrine Pancreatic Function

scientific article published on 01 July 2019

Pancreatic diseases: update 2011

scientific article

Pancreatic duct obstruction triggers acute necrotizing pancreatitis in the opossum

scientific article published on 01 March 1993

Pancreatic outflow obstruction as the critical event for human gall stone induced pancreatitis.

scientific article

Pancreatic pseudocysts--when and how to treat?

scientific article

Papillary mesothelioma of the peritoneum in the absence of asbestos exposure

scientific article published on 01 April 2003

Pathophysiology of alcohol-induced pancreatitis

scientific article published in November 2003

Patterns of Recurrence After Resection of Pancreatic Ductal Adenocarcinoma: A Secondary Analysis of the ESPAC-4 Randomized Adjuvant Chemotherapy Trial

scientific article published on 04 September 2019

Perceptions of genetic testing in patients with hereditary chronic pancreatitis and their families: a qualitative triangulation

scientific article published on 12 August 2020

Percutaneous biliary drainage in patients with nondilated intrahepatic bile ducts compared with patients with dilated intrahepatic bile ducts

scientific article

Percutaneous endoscopic gastrostomy site metastasis in a patient with esophageal cancer

scientific article published on 01 May 2004

Periodontitis and Non-alcoholic Fatty Liver Disease, a population based cohort investigation in the Study of Health in Pomerania.

scientific article published on 14 August 2017

Pharmacological prevention and treatment of acute pancreatitis: where are we now?

scientific article

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

scientific article published on 29 October 2019

Physical Activity, Energy Expenditure, Nutritional Habits, Quality of Sleep and Stress Levels in Shift-Working Health Care Personnel

scientific article (publication date: 12 January 2017)

Plasma protein profiling of patients with intraductal papillary mucinous neoplasm of the pancreas as potential precursor lesions of pancreatic cancer

scientific article published on 5 December 2017

Postoperative adaptation of the small intestine after total colectomy and J-pouch-anal anastomosis

scientific article published on 01 July 1989

Potential for Screening for Pancreatic Exocrine Insufficiency Using the Fecal Elastase-1 Test.

scientific article published on 17 March 2017

Pre-study protocol MagPEP: a multicentre randomized controlled trial of magnesium sulphate in the prevention of post-ERCP pancreatitis

scientific article

Precipitation of hereditary angioedema by infectious mononucleosis

scientific article published on 01 October 1993

Predictive factors for and incidence of hospital readmissions of patients with acute and chronic pancreatitis.

scientific article published on 31 March 2015

Presence of cathepsin B in the human pancreatic secretory pathway and its role in trypsinogen activation during hereditary pancreatitis

scientific article

Prevalence and determinants of increased serum lipase levels in a general population

scientific article published in November 2008

Prevalence of Fatty Liver Disease and Hepatic Iron Overload in a Northeastern German Population by Using Quantitative MR Imaging.

scientific article published on 5 May 2017

Preventing pancreatitis by protecting the mitochondrial permeability transition pore

scientific article published on 20 December 2012

Prevention of postoperative adhesions by single intraperitoneal medication

scientific article published on 01 December 1995

Prof. Dr. Peter Layer ⬇️

scientific article published on August 15, 2012

Prophylactic glycine administration attenuates pancreatic damage and inflammation in experimental acute pancreatitis

scientific article published on 08 April 2011

Prospective cohort study comparing transient EUS guided elastography to EUS-FNA for the diagnosis of solid pancreatic mass lesions

scientific article published on 02 November 2015

Prospective study on the incidence, prevalence and 5-year pancreatic-related mortality of pancreatic cysts in a population-based study.

scientific article published on 6 September 2017

Protection of intestinal anastomoses by biodegradable intraluminal bypass tubes under the condition of general peritonitis: an experimental study on the CLP model in rats

scientific article published on February 1993

Psychometric evaluation of a patient-reported outcome measure in pancreatic exocrine insufficiency (PEI)

scientific article published on 27 November 2018

Qualitative Assessment of the Symptoms and Impact of Pancreatic Exocrine Insufficiency (PEI) to Inform the Development of a Patient-Reported Outcome (PRO) Instrument

scientific article

Quality control of parenteral nutrition in hospitalized patients

scientific article published on 23 October 2013

RESPONSE: re: maternal inheritance pattern of hereditary pancreatitis in patients with pancreatic carcinoma

article published in 1999

Randomised clinical trial: a 1‐week, double‐blind, placebo‐controlled study of pancreatin 25 000 Ph. Eur. minimicrospheres (Creon 25000 MMS) for pancreatic exocrine insufficiency after pancreatic surgery, with a 1‐year open‐label extension ⬇️

scientific article published on February 5, 2013

Recent advances in autoimmune pancreatitis: type 1 and type 2.

scientific article published on 08 June 2013

Recommendations from the United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis

Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer

scientific article published on 05 December 2011

Recurrent Acute Pancreatitis: International State-of-the-Science Conference With Recommendations

scientific article published on 01 July 2018

Reducing uncertainty in estimating associations of oral exposures with Helicobacter pylori serology in the general population

scientific article published on 27 July 2018

Reply

scientific article published on 03 April 2018

Reply

Republished: recent advances in autoimmune pancreatitis: type 1 and type 2.

scientific article published on January 2014

Results of intersphincteric resection of the rectum with direct coloanal anastomosis for rectal carcinoma

scientific article published on 01 April 1992

Retinoic acid receptor antagonists inhibit miR-10a expression and block metastatic behavior of pancreatic cancer

scientific article

Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis

scientific article

Role of endoplasmic reticulum stress and protein misfolding in disorders of the liver and pancreas

scientific article published on 09 April 2019

Roles of autophagy and metabolism in pancreatic cancer cell adaptation to environmental challenges

scientific article published on 13 July 2017

S2k guideline: quality requirements for gastrointestinal endoscopy, AWMF registry no. 021-022

scientific article published in December 2015

S3-Leitlinie Chronische Pankreatitis: Definition, Ätiologie, Diagnostik, konservative, interventionell endoskopische und operative Therapie der chronischen Pankreatitis. Leitlinie der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheit

S3-guideline exocrine pancreatic cancer

scientific article

SPINK1 mutations and phenotypic expression in patients with pancreatitis associated with trypsinogen mutations

scientific article published on April 2003

Schlangenbiss

scientific article published on 01 July 2017

Secretin-stimulated MRCP in volunteers: assessment of safety, duct visualization, and pancreatic exocrine function

scientific article published on 01 January 2014

Sonographic changes of the pancreas in chronic renal failure

scientific article published on 01 January 1989

Specificity of a Polyclonal Fecal Elastase ELISA for CELA3.

scientific article

Sphincter stenosis and gallstone migration through the biliary tract

scientific article published in May 1993

Spontaneous and sporadic trypsinogen mutations in idiopathic pancreatitis

scientific article published in November 2002

Status quo Gastroenterologie

Stimulation of pancreatic growth by cholecystokinin is mediated by high affinity receptors on rat pancreatic acinar cells

scientific article published on 01 June 1993

Subjects with sonographical hepatic steatosis should be excluded from studies to establish upper reference levels of serum transaminases

scientific article published on 15 November 2010

Successful drainage of recurrent pancreatic pseudocyst via a transpapillary and transpancreatic approach, using a conventional cystotome

scientific article published on 23 May 2012

Supramaximal secretagogue stimulation enhances heat shock protein expression in the rat pancreas

scientific article

Systemic granulomatous disease after intravesical BCG instillation

scientific article published on January 2000

Tests of pancreatic exocrine function - clinical significance in pancreatic and non-pancreatic disorders.

scientific article published on January 2009

The 5th International Symposium on Inherited Diseases of the Pancreas

scientific article published in January 2006

The Clinical and Socio-Economic Relevance of Increased IPMN Detection Rates and Management Choices

scientific article (publication date: February 2015)

The Complex Role of Trypsin in Pancreatitis

scientific article published on 03 January 2020

The Impact of Positive Resection Margins on Survival and Recurrence Following Resection and Adjuvant Chemotherapy for Pancreatic Ductal Adenocarcinoma.

scientific article published on 24 October 2017

The Importance of Aquaporin 1 in Pancreatitis and Its Relation to the CFTR Cl Channel

scientific article published on 12 July 2018

The PNPLA3 SNP rs738409:G allele is associated with increased liver disease-associated mortality but reduced overall mortality in a population-based cohort

scientific article published on 11 December 2017

The anti-inflammasome effect of lactate and the lactate GPR81-receptor in pancreatic and liver inflammation

scientific article published on 26 April 2014

The benefits of diagnostic ERCP in autoimmune pancreatitis ⬇️

scientific article published on February 11, 2011

The calcium binding protein S100A9 is essential for pancreatic leukocyte infiltration and induces disruption of cell-cell contacts

scientific article published in August 2008

The carboxyl-terminal tyrosine residue of protein-tyrosine phosphatase alpha mediates association with focal adhesion plaques

scientific article published on February 2000

The clinician's guide to pancreaticobiliary disorders.

scientific article published in July 2007

The combined effects of alcohol consumption and body mass index on hepatic steatosis in a general population sample of European men and women.

scientific article published on 15 January 2015

The double duct sign in patients with malignant and benign pancreatic lesions

scientific article published in July 2000

The effect of chloroquine administration on two experimental models of acute pancreatitis.

scientific article published on June 1993

The impact of diabetes mellitus on survival following resection and adjuvant chemotherapy for pancreatic cancer

scientific article

The impact of physiological stress conditions on protein structure and trypsin inhibition of serine protease inhibitor Kazal type 1 (SPINK1) and its N34S variant

scientific article published on 13 September 2019

The number of tandem repeats in the carboxyl-ester lipase (CEL) gene as a risk factor in alcoholic and idiopathic chronic pancreatitis

article

The phosphatase PHLPP1 regulates Akt2, promotes pancreatic cancer cell death, and inhibits tumor formation.

scientific article

The potential role of kinesin and dynein in Golgi scattering and cytoplasmic vacuole formation during acute experimental pancreatitis

scientific article published on 6 April 2010

The revised version of standard terminology in gastroenterological endoscopy - result of a consensus project of the german society for gastroenterology, digestive and metabolic diseases

scientific article published on 15 November 2017

The revised version of standard terminology in gastroenterological endoscopy - result of a consensus project of the german society for gastroenterology, digestive and metabolic diseases

scientific article published in December 2017

The role of antibiotic prophylaxis in the treatment of acute pancreatitis

scientific article published on 01 February 2006

The role of bile acids in gallstone-induced pancreatitis

scientific article published on 22 December 2009

The role of intracellular calcium signaling in premature protease activation and the onset of pancreatitis.

scientific article published on July 2000

The role of kinesin, dynein and microtubules in pancreatic secretion.

scientific article published on 2 June 2009

The role of nitric oxide in hemodynamic and metabolic alterations induced by prostaglandin F2 alpha in the perfused rat liver.

scientific article

The role of thoracic epidural analgesia in receptor-dependent and receptor-independent pulmonary vasoconstriction in experimental pancreatitis

scientific article

The shaping, making and baking of a pancreatologist

scientific article published on 21 April 2018

Third International Symposium on Inherited Diseases of the Pancreas

scientific article published on 01 January 2001

Thoracic epidural analgesia augments ileal mucosal capillary perfusion and improves survival in severe acute pancreatitis in rats

scientific article published on 01 August 2006

Three centuries since the discovery of Vater's Papilla

scientific article published on 30 July 2020

Time after excision and temperature alter ex vivo tissue relaxation time measurements.

scientific article published on September 1994

Toll-like receptor 4 polymorphisms in German and US patients are not associated with occurrence or severity of acute pancreatitis

article

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

scientific article published on 01 September 2020

Treatment of menstruation-associated recurrence of hereditary pancreatitis with pharmacologic ovarian suppression

scientific article

Treatment of severe neurological deficits with IgG depletion through immunoadsorption in patients with Escherichia coli O104:H4-associated haemolytic uraemic syndrome: a prospective trial

scientific article

Trypsin activity is not involved in premature, intrapancreatic trypsinogen activation

scientific article published in February 2002

Trypsin reduces pancreatic ductal bicarbonate secretion by inhibiting CFTR Cl⁻ channels and luminal anion exchangers.

scientific article

Tumour necrosis factor α secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice

scientific article published on 5 April 2012

Tumour-specific delivery of siRNA-coupled superparamagnetic iron oxide nanoparticles, targeted against PLK1, stops progression of pancreatic cancer.

scientific article published on 12 May 2016

Ultrasonography of benign adrenal tumours

scientific article published on 01 September 1992

United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis (HaPanEU).

scientific article published on 16 January 2017

Up-regulation, nuclear import, and tumor growth stimulation of the adhesion protein p120 in pancreatic cancer

scientific article published in April 2003

Usual ductal hyperplasia of the breast is a committed stem (progenitor) cell lesion distinct from atypical ductal hyperplasia and ductal carcinoma in situ

scientific article published on 01 December 2002

Variants in ABCG8 and TRAF3 genes confer risk for gallstone disease in admixed Latinos with Mapuche Native American ancestry

scientific article published in Scientific Reports

Vascular smooth muscle and nitric oxide synthase

scientific article published in April 2002

Vasoactive mediators and the progression from oedematous to necrotising experimental acute pancreatitis

scientific article

Verbesserung der Kostenkalkulation in der Gastroenterologie durch Einführung eines neuen Leistungskatalogs für alle endoskopischen Prozeduren

scientific article published on 16 March 2015

Why does pancreatic overstimulation cause pancreatitis?

scientific article published on January 2007

Why is one arm stronger than two arms? IgG4 antibodies in IgG4-related autoimmune pancreatitis

scientific article published on 21 April 2016

Zymogen proteolysis within the pancreatic acinar cell is associated with cellular injury

scientific article published on 01 November 1998

[Autoimmune pancreatitis].

scientific article

[Boceprevir-benefit assessment by the Institute for Quality and Efficiency in Health Care (IQWiG) in accordance with § 35a SGB V (dosage evaluation)]

scientific article published on 05 January 2012

[Chronic pancreatitis. Diagnosis and treatment]

scientific article published on 01 July 2004

[Conservative treatment of acute pancreatitis]

scientific article published on 10 September 2008

[Cooperation between clinicians and pathologists]

scientific article published on 01 January 2001

[Economic burden of Clostridium difficile enterocolitis in German hospitals based on routine DRG data].

scientific article

[Internal medicine - between cross-cutting and caring]

scientific article published on 02 December 2019

[Intraluminal splinting of problematic intestinal anastomoses with biomaterial tubes]

scientific article published on 01 January 1989

[New guidelines on chronic pancreatitis : interdisciplinary treatment strategies]

scientific article published on 01 February 2013

[Pancreatic disorders : What is new?]

scientific article published on 01 March 2019

[Postoperative, intra-abdominal adhesions--a new standardized and objective animal model and testing of substances for the prevention of adhesions]

scientific article published on 01 January 1989

[Prognostic significance and economic burden of hepatic encephalopathy in liver cirrhosis in German hospitals based on G-DRG data]

scientific article published on 20 December 2019

[Rare cause of hypercalcemia]

scientific article published on 01 March 2009

[Role of protease activation in pathophysiology of acute pancreatitis]

scientific article published on 01 January 1998

[S2k guideline: quality requirements for gastrointestinal endoscopy, AWMF registry no. 021-022]

scientific article published on 14 December 2015

[Snake bite in a 53-year-old female tourist]

scientific article published on 01 February 2015

[The direct ileum pouch-anal anastomosis. Clinical and functional continence results]

scientific article published on 01 September 1989

[Ultrastructural morphologic and mineral analytic studies of the pancreas of uremic rats]

scientific article published on 01 January 1987

[Wolfgang Schepp MD - Introduction of the conference chairman 2018 of the German Society of Gastroenterology, Digestive and Metabolic Diseases]

scientific article published on 13 August 2018

p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I

scientific journal article

Paulina is supported by:

About Paulina

Help