List of works - Giangennaro Coppola

A 12-month longitudinal study of calcium metabolism and bone turnover during valproate monotherapy.

scientific article published on 13 August 2009

A low cost amplifier and acquisition system for cortical-electroncephalography in non-human applications

scientific article

A multicenter, randomized, placebo-controlled trial of levetiracetam in children and adolescents with newly diagnosed absence epilepsy

scientific article published on 14 February 2011

A mutation (V260M) in the middle of the M2 pore-lining domain of the glycine receptor causes hereditary hyperekplexia.

scientific article published in November 2001

A novel hyperekplexia-causing mutation in the pre-transmembrane segment 1 of the human glycine receptor alpha1 subunit reduces membrane expression and impairs gating by agonists.

scientific article published on 5 April 2004

Analysis of LGI1 promoter sequence, PDYN and GABBR1 polymorphisms in sporadic and familial lateral temporal lobe epilepsy.

scientific article

Anticonvulsant drugs and hematological disease

scientific article

Anticonvulsant drugs for generalized tonic-clonic epilepsy

scientific article published on 8 May 2017

Anticonvulsant properties of an oral ketone ester in a pentylenetetrazole-model of seizure

scientific article

Antiepileptic drug withdrawal in childhood epilepsy: what are the risk factors associated with seizure relapse?

scientific article published on 6 March 2012

Association between SCN1A gene polymorphisms and drug resistant epilepsy in pediatric patients.

scientific article published on 5 January 2018

Association of intronic variants of the KCNAB1 gene with lateral temporal epilepsy

scientific article published in March 2011

Attention deficit hyperactivity disorder in genetically-determined intellectual disability

scientific article published on 23 July 2018

Autosomal dominant lateral temporal epilepsy: Absence of mutations in ADAM22 and Kv1 channel genes encoding LGI1-associated proteins

scientific article published in July 2008

Benign Familial Neonatal Convulsions Caused by Altered Gating of KCNQ2/KCNQ3 Potassium Channels ⬇️

scientific article (publication date: 15 January 2002)

Benign convulsions associated with mild gastroenteritis: a multicenter clinical study

scientific article published on 10 December 2010

Benign familial neonatal convulsions (BFNC) resulting from mutation of the KCNQ2 voltage sensor

scientific article (publication date: December 2000)

Benign idiopathic partial seizures in the velocardiofacial syndrome: report of two cases.

scientific article published in October 2001

Bone and calcium metabolism and antiepileptic drugs.

scientific article

Bone mineral density in a population of children and adolescents with cerebral palsy and mental retardation with or without epilepsy

scientific article published on 7 September 2012

Brain anatomical substrates of mirror movements in Kallmann syndrome.

scientific article published on 6 October 2014

Brainstem arteriovenous malformation presenting with dyspraxic handwriting in a young girl

scientific article published in August 2013

Catamenial epilepsy: hormonal aspects.

scientific article

Cerebellar vermis defect, oligophrenia, congenital ataxia, and hepatic fibrocirrhosis without coloboma and renal abnormalities: report of three cases.

scientific article

Characterization of two de novoKCNT1 mutations in children with malignant migrating partial seizures in infancy

scientific article published on 16 January 2016

Clinical Guidelines for Management of Bone Health in Rett Syndrome Based on Expert Consensus and Available Evidence

scientific article

Clinical dissection of childhood occipital epilepsy of Gastaut and prognostic implication

scientific article published on 25 October 2015

Clinical features of psychogenic non-epileptic seizures in prepubertal and pubertal patients with idiopathic epilepsy.

scientific article published on 17 June 2009

Cognitive Profile, Emotional-Behavioral Features, and Parental Stress in Boys With 47,XYY Syndrome

scientific article published on 01 June 2019

Cognitive and linguistic abnormalities in benign childhood epilepsy with centrotemporal spikes

scientific article published on 14 February 2011

Commentary on "benign afebrile convulsions in the course of mild acute gastroenteritis"

scientific article published on 01 August 2012

Conduct disorders and psychopathy in children and adolescents: aetiology, clinical presentation and treatment strategies of callous-unemotional traits

scientific article published on 20 September 2017

Correlating the clinical and genetic features of benign familial neonatal seizures (BFNS) with the functional consequences of underlying mutations

scientific article published on 01 July 2007

Current role of perampanel in pediatric epilepsy.

scientific article published on 02 June 2017

Current role of rufinamide in the treatment of childhood epilepsy: literature review and treatment guidelines.

scientific article

Detection of soluble BAG3 and anti-BAG3 antibodies in patients with chronic heart failure ⬇️

scientific article published on February 14, 2013

Differences in Metabolic Factors Between Antipsychotic-Induced Weight Gain and Non-pharmacological Obesity in Youths

scientific article published on 12 February 2018

Different Immune Signature in Youths Experiencing Antipsychotic-Induced Weight Gain Compared to Untreated Obese Patients.

scientific article published on 28 April 2017

Different calorie restriction treatments have similar anti-seizure efficacy.

scientific article published on 7 January 2016

Digital Devices Use and Language Skills in Children between 8 and 36 Month

scientific article published on 21 September 2020

Early onset absence epilepsy with onset in the first year of life: a multicenter cohort study.

scientific article

Effectiveness and tolerability of perampanel in children and adolescents with refractory epilepsies-An Italian observational multicenter study.

scientific article published on 18 August 2016

Effects of the abrupt switch from solution to modified-release granule formulation of valproate

scientific article published on 28 June 2011

Efficacy and safety of felbamate in children under 4 years of age: a retrospective chart review.

scientific article published on 10 July 2008

Efficacy and safety of levetiracetam in infants and young children with refractory epilepsy

scientific article published on 26 March 2007

Efficacy and safety of rufinamide in children under four years of age with drug-resistant epilepsies.

scientific article

Efficacy and tolerability of add-on lacosamide in children with Lennox-Gastaut syndrome

scientific article published on 30 January 2014

Electroclinical features and long-term outcome of cryptogenic epilepsy in children with Down syndrome.

scientific article published on 27 August 2013

Electroclinical features of epilepsy monosomy 1p36 syndrome and their implications

scientific article published on 14 August 2018

Epilepsy and electroencephalographic anomalies in chromosome 2 aberrations. A review.

scientific article published on 20 February 2008

Epilepsy and genetic in Rett syndrome: A review

scientific article published on 30 March 2019

Epilepsy in Menkes disease: an electroclinical long-term study of 28 patients.

scientific article

Epilepsy in children with Menkes disease: a systematic review of literature

scientific article published on 17 July 2014

Epilepsy in patients with Cornelia de Lange syndrome: a clinical series.

scientific article published on 7 March 2013

Epilepsy in the setting of full trisomy 18: A multicenter study on 18 affected children with and without structural brain abnormalities

scientific article

Epilepsy, sex hormones and antiepileptic drugs in female patients.

scientific article published on December 2009

Epileptic encephalopathies in children

scientific article published on 22 August 2013

Facial Emotion Recognition in Children and Adolescents with Specific Learning Disorder

scientific article published on 23 July 2020

Familial Hemiplegic Migraine with an ATP1A4 Mutation: Clinical Spectrum and Carbamazepine Efficacy

scientific article published on 15 June 2020

First long-term experience with the orphan drug rufinamide in children with myoclonic-astatic epilepsy (Doose syndrome)

scientific article published on 21 January 2012

Gastaut type-idiopathic childhood occipital epilepsy and childhood absence epilepsy: a clinically significant association?

scientific article published on 14 May 2010

Genetic heterogeneity in malignant migrating partial seizures of infancy

scientific article published on 02 January 2014

Heterozygous reelin mutations cause autosomal-dominant lateral temporal epilepsy

scientific article published on June 2015

Hormonal and reproductive disturbances in epileptic male patients: emerging issues.

scientific article published on 18 February 2011

Hyperekplexia caused by dominant-negative suppression of glyra1 function

scientific article published on 01 May 2007

Idiopathic generalized tonic-clonic epilepsy and photosensitivity: a long-term follow-up study.

scientific article published on 6 August 2009

Impact of dietary fats on brain functions

scientific article

Improving molecular diagnosis in epilepsy by a dedicated high-throughput sequencing platform

scientific article

Investigational small molecules in phase II clinical trials for the treatment of epilepsy: cannabidivarin, selurampanel (BGG492) and ganaxolone

scientific article published on 13 November 2018

Ketogenic diet and childhood neurological disorders other than epilepsy: an overview.

scientific article published on 14 November 2016

Ketogenic diet for the treatment of catastrophic epileptic encephalopathies in childhood.

scientific article published on 25 July 2009

Ketogenic diet prevents neuronal firing increase within the substantia nigra during pentylenetetrazole-induced seizure in rats.

scientific article published on 2 July 2016

Kleefstra-variant syndrome with heterozygous mutations in EHMT1 and KCNQ2 genes: a case report

scientific article

Lack of pathogenic mutations in six patients with MMPSI.

scientific article

Lacosamide in pediatric and adult patients: comparison of efficacy and safety.

scientific article published on 5 January 2013

Lamotrigine as add-on drug in children and adolescents with refractory epilepsy and mental delay: an open trial ⬇️

scientific article published on September 1, 1997

Lamotrigine versus valproic acid as first-line monotherapy in newly diagnosed typical absence seizures: an open-label, randomized, parallel-group study.

scientific article

Levetiracetam during 1-year follow-up in children, adolescents, and young adults with refractory epilepsy.

scientific article

Levetiracetam in absence epilepsy.

scientific article published on 19 September 2008

Levetiracetam in juvenile myoclonic epilepsy: long-term efficacy in newly diagnosed adolescents.

scientific article published in January 2008

Levetiracetam monotherapy for children and adolescents with benign rolandic seizures.

scientific article published on 3 January 2007

Levetiracetam or oxcarbazepine as monotherapy in newly diagnosed benign epilepsy of childhood with centrotemporal spikes (BECTS): an open-label, parallel group trial.

scientific article published on 20 October 2006

Long term outcome in children affected by absence epilepsy with onset before the age of three years

scientific article published on 11 January 2011

Long-term follow-up in children with benign convulsions associated with gastroenteritis

scientific article published on 14 April 2014

Long-term outcome of autistic spectrum disorder: a retrospective case study in a southern italian region.

scientific article published on 20 September 2017

Long-term outcome of epilepsy in Kabuki syndrome.

scientific article published on 7 July 2011

Low glycemic index diet in children and young adults with refractory epilepsy: First Italian experience ⬇️

scientific article published on April 13, 2011

Low long-term efficacy and tolerability of add-on rufinamide in patients with Dravet syndrome

scientific article published on 28 May 2011

Low penetrance and effect on protein secretion of LGI1 mutations causing autosomal dominant lateral temporal epilepsy

scientific article published on 19 April 2011

Low penetrance of autosomal dominant lateral temporal epilepsy in Italian families without LGI1 mutations.

scientific article published on 26 April 2013

Malignant migrating partial seizures in infancy.

scientific article published on January 2013

Malignant migrating partial seizures in infancy: an epilepsy syndrome of unknown etiology.

scientific article

Management of psychogenic nonepileptic seizures (PNES): a multidisciplinary approach

scientific article published on 29 November 2018

Monitoring And Managing Depression In Adolescents With Epilepsy: Current Perspectives

scientific article published on 24 September 2019

Mozart's music in children with drug-refractory epileptic encephalopathies.

scientific article

Mozart's music in children with drug-refractory epileptic encephalopathies: Comparison of two protocols

scientific article

Mutational scanning of potassium, sodium and chloride ion channels in malignant migrating partial seizures in infancy.

scientific article published on 15 September 2005

Neonatal sporadic hyperekplexia: a rare and often unrecognized entity.

scientific article

Neuropsychological impairment in childhood absence epilepsy: Review of the literature.

scientific article published on 23 October 2015

Neuropsychological impairment in children with Rolandic epilepsy and in their siblings

scientific article published on 22 May 2013

Neuropsychological profiles and outcomes in children with new onset frontal lobe epilepsy.

scientific article published on 12 January 2016

New developments in the management of partial-onset epilepsy: role of brivaracetam

scientific article published on 06 March 2017

Non-resective surgery and radiosurgery for treatment of drug-resistant epilepsy.

scientific article published on 13 January 2012

Nonalcoholic fatty liver disease in adolescents receiving valproic acid

scientific article

Nutritional problems in children with neuromotor disabilities: an Italian case series

scientific article

Obese children suffer more often from migraine ⬇️

scientific article published on September 1, 2012

Parental stress in a sample of children with epilepsy

scientific article published on 05 May 2019

Parental stress in pediatric epilepsy after therapy withdrawal

scientific article published on 09 April 2019

Peri-ictal and inter-ictal headache in children and adolescents with idiopathic epilepsy: a multicenter cross-sectional study.

scientific article

Phenytoin neurotoxicity in a child carrying new STXBP1 and CYP2C9 gene mutations

article

Plasma free carnitine in epilepsy children, adolescents and young adults treated with old and new antiepileptic drugs with or without ketogenic diet.

scientific article published on 10 January 2006

Psychiatric Manifestation of EAST Syndrome: Case Report and a Critical Assessment of Psychiatric Issues.

scientific article published on 9 February 2016

Psychogenic Non-Epileptic Status as Refractory, Generalized Hypertonic Posturing: Report of Two Adolescents

scientific article published on 28 September 2020

Putative mechanisms of action and clinical use of lithium in children and adolescents: a critical review.

scientific article published on 19 December 2017

Reflex myoclonic epilepsy in infancy: a multicenter clinical study.

scientific article

Refractory absence seizures: An Italian multicenter retrospective study.

scientific article published on 18 July 2015

Role of folic acid depletion on homocysteine serum level in children and adolescents with epilepsy and different MTHFR C677T genotypes

scientific article published on 16 March 2012

Rufinamide for refractory focal seizures: an open-label, multicenter European study

scientific article published on 16 October 2012

Rufinamide for the treatment of refractory epilepsy secondary to neuronal migration disorders

scientific article published on 30 January 2014

Rufinamide in children and adults with Lennox-Gastaut syndrome: first Italian multicenter experience.

scientific article published on November 2010

Rufinamide in refractory childhood epileptic encephalopathies other than Lennox-Gastaut syndrome

scientific article

Should "migralepsy" be considered an obsolete concept? A multicenter retrospective clinical/EEG study and review of the literature.

scientific article published on 15 April 2011

Simultaneous onset of infantile spasms in monozygotic twins

scientific article published on 01 August 2010

Startle epilepsy associated with infantile hemiplegia (SEIH): video-polygraphic features and long-term outcome.

scientific article published in April 2009

Successful Treatment of Refractory Seizures With Rufinamide in Children With Schizencephaly: Report of 3 Cases

scientific article published on 22 July 2014

Teachers of various school grades and representations of epilepsy: problems, relational aspects and perspectives of life quality

scientific article published on 5 October 2015

Temporal lobe dual pathology in malignant migrating partial seizures in infancy.

scientific article published on June 2007

The clinical phenotype of autosomal dominant lateral temporal lobe epilepsy related to reelin mutations.

scientific article

The effects of the ketogenic diet in refractory partial seizures with reference to tuberous sclerosis

scientific article published on 24 April 2006

The impact of the ketogenic diet on arterial morphology and endothelial function in children and young adults with epilepsy: a case-control study

scientific article

The ketogenic diet for Dravet syndrome and other epileptic encephalopathies: an Italian consensus.

scientific article published on April 2011

The ketogenic diet in children, adolescents and young adults with refractory epilepsy: an Italian multicentric experience.

scientific article

The pharmacological management of Lennox-Gastaut syndrome and critical literature review

scientific article published on 26 October 2018

Topiramate in frontal lobe epilepsy.

scientific article published in February 2007

Treatment of malignant migrating partial epilepsy of infancy with rufinamide: report of five cases

scientific article

Treatment of partial seizures in childhood : an overview.

scientific article published on January 2004

Tuberous sclerosis complex and hydrosyringomielia: Report of two cases.

scientific article published in January 2006

Unusual compulsive motor activity during treatment with clothiapine in a mentally retarded adolescent.

scientific article

Update on rufinamide in childhood epilepsy ⬇️

scientific article published on 05 July 2011

Update on the role of eslicarbazepine acetate in the treatment of partial-onset epilepsy

scientific article

Update on the safety of second generation antipsychotics in youths: a call for collaboration among paediatricians and child psychiatrists

scientific article

Vaccination and occurrence of seizures in SCN1A mutation-positive patients: a multicenter Italian study

scientific article

Valproic acid and phenobarbital blood levels during the first month of treatment with the ketogenic diet.

scientific article published on October 2010

Vigabatrin as add-on therapy in children and adolescents with refractory epilepsy: an open trial ⬇️

scientific article published on November 1, 1997

Weight gain following treatment with valproic acid: pathogenetic mechanisms and clinical implications ⬇️

scientific article published on 06 September 2010

Weight regain after discontinuation of topiramate treatment in patients with migraine: a prospective observational study

scientific article published in February 2015

Zonisamide in children and young adults with refractory epilepsy: an open label, multicenter Italian study.

scientific article

List of works by Giangennaro Coppola

A 12-month longitudinal study of calcium metabolism and bone turnover during valproate monotherapy.

A low cost amplifier and acquisition system for cortical-electroncephalography in non-human applications

A multicenter, randomized, placebo-controlled trial of levetiracetam in children and adolescents with newly diagnosed absence epilepsy

A mutation (V260M) in the middle of the M2 pore-lining domain of the glycine receptor causes hereditary hyperekplexia.

A novel hyperekplexia-causing mutation in the pre-transmembrane segment 1 of the human glycine receptor alpha1 subunit reduces membrane expression and impairs gating by agonists.

Analysis of LGI1 promoter sequence, PDYN and GABBR1 polymorphisms in sporadic and familial lateral temporal lobe epilepsy.

Anticonvulsant drugs and hematological disease

Anticonvulsant drugs for generalized tonic-clonic epilepsy

Anticonvulsant properties of an oral ketone ester in a pentylenetetrazole-model of seizure

Antiepileptic drug withdrawal in childhood epilepsy: what are the risk factors associated with seizure relapse?

Association between SCN1A gene polymorphisms and drug resistant epilepsy in pediatric patients.

Association of intronic variants of the KCNAB1 gene with lateral temporal epilepsy

Attention deficit hyperactivity disorder in genetically-determined intellectual disability

Autosomal dominant lateral temporal epilepsy: Absence of mutations in ADAM22 and Kv1 channel genes encoding LGI1-associated proteins

Benign Familial Neonatal Convulsions Caused by Altered Gating of KCNQ2/KCNQ3 Potassium Channels ⬇️

Benign convulsions associated with mild gastroenteritis: a multicenter clinical study

Benign familial neonatal convulsions (BFNC) resulting from mutation of the KCNQ2 voltage sensor

Benign idiopathic partial seizures in the velocardiofacial syndrome: report of two cases.

Bone and calcium metabolism and antiepileptic drugs.

Bone mineral density in a population of children and adolescents with cerebral palsy and mental retardation with or without epilepsy

Brain anatomical substrates of mirror movements in Kallmann syndrome.

Brainstem arteriovenous malformation presenting with dyspraxic handwriting in a young girl

Catamenial epilepsy: hormonal aspects.

Cerebellar vermis defect, oligophrenia, congenital ataxia, and hepatic fibrocirrhosis without coloboma and renal abnormalities: report of three cases.

Characterization of two de novoKCNT1 mutations in children with malignant migrating partial seizures in infancy

Clinical Guidelines for Management of Bone Health in Rett Syndrome Based on Expert Consensus and Available Evidence

Clinical dissection of childhood occipital epilepsy of Gastaut and prognostic implication

Clinical features of psychogenic non-epileptic seizures in prepubertal and pubertal patients with idiopathic epilepsy.

Cognitive Profile, Emotional-Behavioral Features, and Parental Stress in Boys With 47,XYY Syndrome

Cognitive and linguistic abnormalities in benign childhood epilepsy with centrotemporal spikes

Commentary on "benign afebrile convulsions in the course of mild acute gastroenteritis"

Conduct disorders and psychopathy in children and adolescents: aetiology, clinical presentation and treatment strategies of callous-unemotional traits

Correlating the clinical and genetic features of benign familial neonatal seizures (BFNS) with the functional consequences of underlying mutations

Current role of perampanel in pediatric epilepsy.

Current role of rufinamide in the treatment of childhood epilepsy: literature review and treatment guidelines.

Detection of soluble BAG3 and anti-BAG3 antibodies in patients with chronic heart failure ⬇️

Differences in Metabolic Factors Between Antipsychotic-Induced Weight Gain and Non-pharmacological Obesity in Youths

Different Immune Signature in Youths Experiencing Antipsychotic-Induced Weight Gain Compared to Untreated Obese Patients.

Different calorie restriction treatments have similar anti-seizure efficacy.

Digital Devices Use and Language Skills in Children between 8 and 36 Month

Early onset absence epilepsy with onset in the first year of life: a multicenter cohort study.

Effectiveness and tolerability of perampanel in children and adolescents with refractory epilepsies-An Italian observational multicenter study.

Effects of the abrupt switch from solution to modified-release granule formulation of valproate

Efficacy and safety of felbamate in children under 4 years of age: a retrospective chart review.

Efficacy and safety of levetiracetam in infants and young children with refractory epilepsy

Efficacy and safety of rufinamide in children under four years of age with drug-resistant epilepsies.

Efficacy and tolerability of add-on lacosamide in children with Lennox-Gastaut syndrome

Electroclinical features and long-term outcome of cryptogenic epilepsy in children with Down syndrome.

Electroclinical features of epilepsy monosomy 1p36 syndrome and their implications

Epilepsy and electroencephalographic anomalies in chromosome 2 aberrations. A review.

Epilepsy and genetic in Rett syndrome: A review

Epilepsy in Menkes disease: an electroclinical long-term study of 28 patients.

Epilepsy in children with Menkes disease: a systematic review of literature

Epilepsy in patients with Cornelia de Lange syndrome: a clinical series.

Epilepsy in the setting of full trisomy 18: A multicenter study on 18 affected children with and without structural brain abnormalities

Epilepsy, sex hormones and antiepileptic drugs in female patients.

Epileptic encephalopathies in children

Facial Emotion Recognition in Children and Adolescents with Specific Learning Disorder

Familial Hemiplegic Migraine with an ATP1A4 Mutation: Clinical Spectrum and Carbamazepine Efficacy

First long-term experience with the orphan drug rufinamide in children with myoclonic-astatic epilepsy (Doose syndrome)

Gastaut type-idiopathic childhood occipital epilepsy and childhood absence epilepsy: a clinically significant association?

Genetic heterogeneity in malignant migrating partial seizures of infancy

Heterozygous reelin mutations cause autosomal-dominant lateral temporal epilepsy

Hormonal and reproductive disturbances in epileptic male patients: emerging issues.

Hyperekplexia caused by dominant-negative suppression of glyra1 function

Idiopathic generalized tonic-clonic epilepsy and photosensitivity: a long-term follow-up study.

Impact of dietary fats on brain functions

Improving molecular diagnosis in epilepsy by a dedicated high-throughput sequencing platform

Investigational small molecules in phase II clinical trials for the treatment of epilepsy: cannabidivarin, selurampanel (BGG492) and ganaxolone

Ketogenic diet and childhood neurological disorders other than epilepsy: an overview.

Ketogenic diet for the treatment of catastrophic epileptic encephalopathies in childhood.

Ketogenic diet prevents neuronal firing increase within the substantia nigra during pentylenetetrazole-induced seizure in rats.

Kleefstra-variant syndrome with heterozygous mutations in EHMT1 and KCNQ2 genes: a case report

Lack of pathogenic mutations in six patients with MMPSI.

Lacosamide in pediatric and adult patients: comparison of efficacy and safety.

Lamotrigine as add-on drug in children and adolescents with refractory epilepsy and mental delay: an open trial ⬇️

Lamotrigine versus valproic acid as first-line monotherapy in newly diagnosed typical absence seizures: an open-label, randomized, parallel-group study.

Levetiracetam during 1-year follow-up in children, adolescents, and young adults with refractory epilepsy.

Levetiracetam in absence epilepsy.