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List of works by Mariusz R Wieckowski

A Diet Induced Maladaptive Increase in Hepatic Mitochondrial DNA Precedes OXPHOS Defects and May Contribute to Non-Alcoholic Fatty Liver Disease

scientific article published on 08 October 2019

A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction.

scientific article

A novel apoptosis-like pathway, independent of mitochondria and caspases, induced by curcumin in human lymphoblastoid T (Jurkat) cells.

scientific article published on June 1999

ATP synthesis and storage

scientific article

Age-related changes in levels of p66Shc and serine 36-phosphorylated p66Shc in organs and mouse tissues

scientific article

Alterations in Mitochondrial and Endoplasmic Reticulum Signaling by p53 Mutants

scientific article

Aortic Valve Stenosis and Mitochondrial Dysfunctions: Clinical and Molecular Perspectives

scientific article published on 11 July 2020

Application of "blue native" electrophoresis in the studies of mitochondrial respiratory chain complexes in physiology and pathology

scientific article published in January 2008

Assessment of mitochondrial function following short- and long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product and reference cigarettes

scientific article published on 12 February 2018

Basal activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth

scientific article

Calcium regulates cell death in cancer: Roles of the mitochondria and mitochondria-associated membranes (MAMs).

scientific article published on 10 January 2017

Calcium signaling around Mitochondria Associated Membranes (MAMs). ⬇️

scientific article published on 22 September 2011

Cancer-Related Increases and Decreases in Calcium Signaling at the Endoplasmic Reticulum-Mitochondria Interface (MAMs)

scientific article published on 14 August 2020

Cardiac mitochondrial dysfunction during hyperglycemia--the role of oxidative stress and p66Shc signaling

scientific article published on 07 July 2012

Cardiotoxicity of the anticancer therapeutic agent bortezomib.

scientific article

Carvedilol and antioxidant proteins in a type I diabetes animal model

scientific article published on 2 November 2016

Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels.

scientific article

Citrate Mediates Crosstalk between Mitochondria and the Nucleus to Promote Human Mesenchymal Stem Cell In Vitro Osteogenesis

scientific article published on 21 April 2020

Comprehensive analysis of mitochondrial permeability transition pore activity in living cells using fluorescence-imaging-based techniques

scientific article

Dietary Polyphenols and Mitochondrial Function: Role in Health and Disease.

scientific article

Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction

scientific article published on 09 August 2018

Disrupted ATP synthase activity and mitochondrial hyperpolarisation-dependent oxidative stress is associated with p66Shc phosphorylation in fibroblasts of NARP patients

scientific article published on 31 July 2012

Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis

scientific article

Early Cardiac Mitochondrial Molecular and Functional Responses to Acute Anthracycline Treatment in Wistar Rats

scientific article published on 01 May 2019

Effect of glucose and deoxyglucose on the redistribution of calcium in ehrlich ascites tumour and Zajdela hepatoma cells and its consequences for mitochondrial energetics. Further arguments for the role of Ca(2+) in the mechanism of the crabtree eff

scientific article published on 01 July 1999

Effect of mtDNA point mutations on cellular bioenergetics ⬇️

scientific article published on March 3, 2012

Effect of selenite on basic mitochondrial function in human osteosarcoma cells with chronic mitochondrial stress.

scientific article published on July 2011

Effects of N-acylethanolamines on mitochondrial energetics and permeability transition

scientific article published in July 2004

Effects of plant alkaloids on mitochondrial bioenergetic parameters

scientific article published in August 2021

Fat and Sugar-A Dangerous Duet. A Comparative Review on Metabolic Remodeling in Rodent Models of Nonalcoholic Fatty Liver Disease

scientific article published on 24 November 2019

Fatty acid-induced uncoupling of oxidative phosphorylation is partly due to opening of the mitochondrial permeability transition pore.

scientific article published in February 1998

From mitochondrial large amplitude swelling to the permeability transition - a short historic overview.

scientific article published on January 2016

Guanosine diphosphate exerts a lower effect on superoxide release from mitochondrial matrix in the brains of uncoupling protein-2 knockout mice: new evidence for a putative novel function of uncoupling proteins as superoxide anion transporters

scientific article published on 12 October 2012

Histoenzymatic methods for visualization of the activity of individual mitochondrial respiratory chain complexes in the muscle biopsies from patients with mitochondrial defects

scientific article published in January 2015

Increased reactive oxygen species (ROS) production and low catalase level in fibroblasts of a girl with MEGDEL association (Leigh syndrome, deafness, 3-methylglutaconic aciduria).

scientific article published in January 2011

Inhibition by purine nucleotides of the release of reactive oxygen species from muscle mitochondria: indication for a function of uncoupling proteins as superoxide anion transporters

scientific article published on 31 March 2011

Interaction of Mitochondria with the Endoplasmic Reticulum and Plasma Membrane in Calcium Homeostasis, Lipid Trafficking and Mitochondrial Structure

scientific article

Interactions between the endoplasmic reticulum, mitochondria, plasma membrane and other subcellular organelles

scientific article

Interorganellar calcium signaling in the regulation of cell metabolism: A cancer perspective

scientific article published on 24 May 2019

Involvement of the dicarboxylate carrier in the protonophoric action of long-chain fatty acids in mitochondria

scientific article published in March 1997

Isolation of crude mitochondrial fraction from cells

scientific article published on January 2015

Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells

scientific article published on 08 October 2009

Isolation of plasma membrane–associated membranes from rat liver

scientific article published on 16 January 2014

Left ventricular noncompaction (LVNC) and low mitochondrial membrane potential are specific for Barth syndrome.

scientific article published on 30 January 2013

Localization and Processing of the Amyloid-β Protein Precursor in Mitochondria-Associated Membranes.

scientific article

Long-chain fatty acid-promoted swelling of mitochondria: further evidence for the protonophoric effect of fatty acids in the inner mitochondrial membrane

scientific article published on 01 April 2000

Long-chain fatty acids promote opening of the reconstituted mitochondrial permeability transition pore.

scientific article

Long-term modulation of mitochondrial Ca2+ signals by protein kinase C isozymes

scientific article published on 19 April 2004

Measuring p66Shc Signaling Pathway Activation and Mitochondrial Translocation in Cultured Cells.

scientific article published on 2 November 2015

Mechanistic Role of mPTP in Ischemia-Reperfusion Injury.

scientific article published on January 2017

Melatonin as a master regulator of cell death and inflammation: molecular mechanisms and clinical implications for newborn care

scientific article published on 08 April 2019

Methods to monitor ROS production by fluorescence microscopy and fluorometry.

scientific article published in January 2014

Methods to monitor and compare mitochondrial and glycolytic ATP production

scientific article published in January 2014

Methyl-beta-cyclodextrin induces mitochondrial cholesterol depletion and alters the mitochondrial structure and bioenergetics

scientific article published on 20 October 2010

Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases

scientific article published on 22 June 2018

Mitochondria as a possible target for nicotine action

scientific article published on 13 June 2019

Mitochondria as an important target in heavy metal toxicity in rat hepatoma AS-30D cells.

scientific article

Mitochondria associated membranes (MAMs) as critical hubs for apoptosis

scientific article published on May 2011

Mitochondria in Multiple Sclerosis: Molecular Mechanisms of Pathogenesis

scientific article published on 28 September 2016

Mitochondria in non-alcoholic fatty liver disease

scientific article published on 26 December 2017

Mitochondria-associated membranes (MAMs) and inflammation.

scientific article published on 28 February 2018

Mitochondria-associated membranes (MAMs) as hotspot Ca(2+) signaling units

scientific article published on January 2012

Mitochondria-associated membranes in aging and senescence: structure, function, and dynamics.

scientific article published on 28 February 2018

Mitochondria-associated membranes: composition, molecular mechanisms, and physiopathological implications

scientific article published on 13 March 2015

Mitochondria-ros crosstalk in the control of cell death and aging

scientific article

Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systems

Mitochondrial Ca(2+) Remodeling is a Prime Factor in Oncogenic Behavior

scientific article published on 25 June 2015

Mitochondrial Ca(2+) and apoptosis

scientific article published on 03 April 2012

Mitochondrial Network and Biogenesis in Response to Short and Long-Term Exposure of Human BEAS-2B Cells to Aerosol Extracts from the Tobacco Heating System 2.2.

scientific article published on 01 March 2020

Mitochondrial alterations accompanied by oxidative stress conditions in skin fibroblasts of Huntington's disease patients.

scientific article published on 17 August 2018

Mitochondrial and endoplasmic reticulum calcium homeostasis and cell death.

scientific article

Mitochondrial calcium homeostasis as potential target for mitochondrial medicine

scientific article published on 21 July 2011

Mitochondrial calcium uniporter complex modulation in cancerogenesis

scientific article published on 10 May 2019

Mitochondrial disruption occurs downstream from β-adrenergic overactivation by isoproterenol in differentiated, but not undifferentiated H9c2 cardiomyoblasts: differential activation of stress and survival pathways.

scientific article published on 16 August 2013

Mitochondrial dysfunction in primary human fibroblasts triggers an adaptive cell survival program that requires AMPK-α.

scientific article published on 20 December 2014

Mitochondrial fatty acid oxidation and oxidative stress: lack of reverse electron transfer-associated production of reactive oxygen species

scientific article published on 18 January 2010

Mitochondrial hyperpolarization during chronic complex I inhibition is sustained by low activity of complex II, III, IV and V.

scientific article

Mitochondrial permeability transition involves dissociation of F1FO ATP synthase dimers and C-ring conformation

scientific article published on 31 May 2017

Mitochondrial reactive oxygen species and inflammation: Molecular mechanisms, diseases and promising therapies

scientific article

Mitochondrial tolerance to drugs and toxic agents in ageing and disease

scientific article published on June 2011

Mitophagy in Cardiovascular Diseases

scientific article published on 24 March 2020

Modulation of mitochondrial dysfunction-related oxidative stress in fibroblasts of patients with Leigh syndrome by inhibition of prooxidative p66Shc pathway.

scientific article published on 21 July 2017

Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury

scientific article

Multiomic analysis on human cell model of wolfram syndrome reveals changes in mitochondrial morphology and function

scientific article published on 20 November 2021

NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4-/- mice and Leigh syndrome patients: A stabilizing role for NDUFAF2

scientific article published on 23 April 2020

Novel c.191C>G (p.Pro64Arg) MPV17 mutation identified in two pairs of unrelated Polish siblings with mitochondrial hepatoencephalopathy

scientific article published on 28 July 2013

Oligomeric C-terminal truncated Bax preferentially releases cytochrome c but not adenylate kinase from mitochondria, outer membrane vesicles and proteoliposomes

scientific article

Oncogenic and oncosuppressive signal transduction at mitochondria-associated endoplasmic reticulum membranes

scientific article published on April 2014

Overexpression of adenine nucleotide translocase reduces Ca2+ signal transmission between the ER and mitochondria.

scientific article published on 25 July 2006

Oxidative stress in cardiovascular diseases and obesity: role of p66Shc and protein kinase C.

scientific article published on 27 March 2013

Oxidative stress-dependent p66Shc phosphorylation in skin fibroblasts of children with mitochondrial disorders

scientific article published on 10 March 2010

PGC-1β mediates adaptive chemoresistance associated with mitochondrial DNA mutations

scientific article

PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment

PML regulates apoptosis at endoplasmic reticulum by modulating calcium release

scientific journal article

Pathological mitophagy disrupts mitochondrial homeostasis in Leber’s hereditary optic neuropathy

Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis

scientific article published on 06 May 2020

Photomodification of mitochondrial proteins by azido fatty acids and its effect on mitochondrial energetics. Further evidence for the role of the ADP/ATP carrier in fatty-acid-mediated uncoupling

scientific article published on 01 September 1996

Physiopathology of the Permeability Transition Pore: Molecular Mechanisms in Human Pathology

scientific article published on 04 July 2020

Plasma membrane associated membranes (PAM) from Jurkat cells contain STIM1 protein is PAM involved in the capacitative calcium entry?

scientific article published on 19 July 2009

Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc

scientific article published on 01 February 2007

Protonophoric activity of fatty acid analogs and derivatives in the inner mitochondrial membrane: a further argument for the fatty acid cycling model

scientific article published on 01 September 1998

Putative Structural and Functional Coupling of the Mitochondrial BKCa Channel to the Respiratory Chain

scientific article

Quantifying ROS levels using CM-H2DCFDA and HyPer.

scientific article published on 11 June 2016

Reactive oxygen species produced by the mitochondrial respiratory chain are involved in Cd2+-induced injury of rat ascites hepatoma AS-30D cells.

scientific article published on 29 September 2006

Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria

scientific journal article

Regulation and protection of mitochondrial physiology by sirtuins.

scientific article published on 20 July 2011

Regulation of Endoplasmic Reticulum-Mitochondria Ca2+ Transfer and Its Importance for Anti-Cancer Therapies

scientific article published on 31 August 2017

Regulation of PKCβ levels and autophagy by PML is essential for high-glucose-dependent mesenchymal stem cell adipogenesis

scientific article published on 06 August 2018

Regulation of mitochondrial structure and function by the F1Fo-ATPase inhibitor protein, IF1.

scientific article published in July 2008

Relation Between Mitochondrial Membrane Potential and ROS Formation

scientific article published on 01 January 2018

Relation between mitochondrial membrane potential and ROS formation.

scientific article

Role of Mitochondria-Associated ER Membranes in Calcium Regulation in Cancer-Specific Settings.

scientific article

Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition

scientific article

Role of the p66Shc protein in physiological state and in pathologies

scientific article

STAT3 Activities and Energy Metabolism: Dangerous Liaisons.

scientific article published on 31 July 2014

Short-term and long-term effects of fatty acids in rat hepatoma AS-30D cells: the way to apoptosis.

scientific article published on February 2006

Swim Training Modulates Mouse Skeletal Muscle Energy Metabolism and Ameliorates Reduction in Grip Strength in a Mouse Model of Amyotrophic Lateral Sclerosis ⬇️

scientific article published on 09 January 2019

Swim Training Modulates Skeletal Muscle Energy Metabolism, Oxidative Stress, and Mitochondrial Cholesterol Content in Amyotrophic Lateral Sclerosis Mice.

scientific article

TB-09CORRELATION BETWEEN LEVEL OF Shc PROTEINS AND PEDIATRIC BRAIN TUMOR MALIGNANCY.

scientific article

Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles

scientific article published on 01 January 2019

Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease

scientific article published on 30 November 2018

The interplay between p66Shc, reactive oxygen species and cancer cell metabolism

scientific article

The mechanisms of fatty acid-induced proton permeability of the inner mitochondrial membrane.

scientific article

The role of mitochondria-associated membranes in cellular homeostasis and diseases

scientific article published on 03 December 2019

Thyroid hormone-induced expression of the ADP/ATP carrier and its effect on fatty acid-induced uncoupling of oxidative phosphorylation

scientific article published on 01 October 1997

Tissue transglutaminase (TG2) protects cardiomyocytes against ischemia/reperfusion injury by regulating ATP synthesis

scientific article published on 10 March 2006

Tumor necrosis factor-α impairs oligodendroglial differentiation through a mitochondria-dependent process

scientific article

Western Diet Causes Obesity-Induced Nonalcoholic Fatty Liver Disease Development by Differentially Compromising the Autophagic Response

scientific article published on 15 October 2020

[Osmolytes and osmoregulation in renal cells]

scientific article published on 01 January 1996

[The role of mitochondrial permeability transition pore in physiology and pathology of the cell]

scientific article published on 01 January 2008

p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner

scientific article

p66Shc aging protein in control of fibroblasts cell fate

scientific article

p66Shc signaling is involved in stress responses elicited by anthracycline treatment of rat cardiomyoblasts.

scientific article published on 30 August 2015

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