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List of works by Mohamed Al-Shabrawey

12/15-Lipoxygenase-derived lipid metabolites induce retinal endothelial cell barrier dysfunction: contribution of NADPH oxidase

scientific article

A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase.

scientific article

Adenosine Deaminase-2-Induced Hyperpermeability in Human Retinal Vascular Endothelial Cells Is Suppressed by MicroRNA-146b-3p

scientific article published on February 2017

Adenosine kinase inhibition protects the kidney against streptozotocin-induced diabetes through anti-inflammatory and anti-oxidant mechanisms

scientific article published on 17 May 2014

Alterations of retinal vasculature in cystathionine-β-synthase heterozygous mice: a model of mild to moderate hyperhomocysteinemia

scientific article published on 10 July 2014

Bioactive Lipids and Pathological Retinal Angiogenesis

scientific article published on 19 November 2018

Bone morphogenetic protein 2: a potential new player in the pathogenesis of diabetic retinopathy

scientific article

Caspase-14 expression impairs retinal pigment epithelium barrier function: potential role in diabetic macular edema

scientific article

Deletion of soluble epoxide hydrolase gene improves renal endothelial function and reduces renal inflammation and injury in streptozotocin-induced type 1 diabetes.

scientific article published on 10 August 2011

Diabetic retinopathy: mechanism, diagnosis, prevention, and treatment.

scientific article published on 19 March 2015

Difference in soft tissue response between immediate and delayed delivery suggests a new mechanism for recombinant human bone morphogenetic protein 2 action in large segmental bone defects

scientific article published on 5 December 2011

Diltiazem enhances the apoptotic effects of proteasome inhibitors to induce prostate cancer cell death

scientific article published on 05 March 2012

Early intervention of tyrosine nitration prevents vaso-obliteration and neovascularization in ischemic retinopathy

scientific article

Effects of hypoxia on glial cell expression of angiogenesis-regulating factors VEGF and TGF-beta

scientific article published on 01 October 1998

Effects of tricalcium silicate cements on osteogenic differentiation of human bone marrow-derived mesenchymal stem cells in vitro

scientific article

HMG-CoA reductase inhibitors (statin) prevents retinal neovascularization in a model of oxygen-induced retinopathy.

scientific article

High-mobility group box-1 protein activates inflammatory signaling pathway components and disrupts retinal vascular-barrier in the diabetic retina.

scientific article

Hyperhomocysteinemia disrupts retinal pigment epithelial structure and function with features of age-related macular degeneration

scientific article published on 14 February 2016

Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: implications in retinal neovascularization ⬇️

scientific article

Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: implications in retinal neovascularization. Diabetes 2011;60:614–624.

scientific article published on 14 February 2013

Inflammation and diabetic retinal microvascular complications

scientific article published on April 2011

Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes

scientific article

New developments in the pathophysiology and management of diabetic retinopathy.

scientific article published on 10 December 2013

Peroxynitrite increases VEGF expression in vascular endothelial cells via STAT3.

scientific article published in November 2005

Peroxynitrite mediates VEGF's angiogenic signal and function via a nitration-independent mechanism in endothelial cells

scientific article published on 23 March 2007

Pigment epithelium-derived factor inhibits retinal microvascular dysfunction induced by 12/15-lipoxygenase-derived eicosanoids.

scientific article

Prediction of diabetic retinopathy: role of oxidative stress and relevance of apoptotic biomarkers.

scientific article

Protection against myocardial ischemia/reperfusion injury by short-term diabetes: enhancement of VEGF formation, capillary density, and activation of cell survival signaling.

scientific article

Recombinant bone morphogenetic protein-2 induces up-regulation of vascular endothelial growth factor and interleukin 6 in human pre-osteoblasts: role of reactive oxygen species.

scientific article published on 29 October 2011

Role of NADPH oxidase and Stat3 in statin-mediated protection against diabetic retinopathy.

scientific article

Role of NADPH oxidase in retinal vascular inflammation.

scientific article published on 31 March 2008

Suppression of retinal peroxisome proliferator-activated receptor gamma in experimental diabetes and oxygen-induced retinopathy: role of NADPH oxidase

scientific article published on 20 September 2008

Targeting Neovascularization in Ischemic Retinopathy: Recent Advances

scientific article

Vascular endothelial growth factor and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives.

scientific article

Vascular endothelial growth factor and diabetic retinopathy: role of oxidative stress

scientific article published in June 2005

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