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List of works by Geoffrey R. Hill

A prognostic model for prolonged event-free survival after autologous or allogeneic blood or marrow transplantation for relapsed and refractory Hodgkin's disease

article

A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria

scientific article

Activation of invariant NKT cells exacerbates experimental visceral leishmaniasis

scientific article

Acute GVHD results in a severe DC defect that prevents T-cell priming and leads to fulminant cytomegalovirus disease in mice

scientific article

Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome.

scientific article

Acute myeloid leukemia stem cell function is preserved in the absence of autophagy

scientific article published on 26 May 2017

Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial.

scientific article published on 14 November 2014

Adult-related haematopoietic stem cell donor experiences and the provision of information and psychosocial support: A systematic literature review

article

Advances in the understanding of acute graft-versus-host disease.

scientific article published on April 2007

Agonistic CD40 mAb-Driven IL12 Reverses Resistance to Anti-PD1 in a T-cell-Rich Tumor.

scientific article

Allergen-encoding bone marrow transfer inactivates allergic T cell responses, alleviating airway inflammation

scientific article

Allergen-induced IL-6 trans-signaling activates γδ T cells to promote type 2 and type 17 airway inflammation.

scientific article published on 28 April 2015

Alloantigen presentation and graft-versus-host disease: fuel for the fire

scientific article published on 30 March 2016

Allogeneic Stem Cell Transplantation with Peripheral Blood Stem Cells Mobilized by Pegylated G-CSF

scientific article published on 01 June 2006

An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition

scientific article

An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation

scientific article published on 3 August 2010

Autophagy and haematopoietic stem cell transplantation.

scientific article

Autophagy is required for stem cell mobilization by G-CSF.

scientific article published on 18 March 2015

Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease.

scientific article published on 22 September 2016

Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology.

scientific article published on 14 January 2016

Bone Marrow Transplantation Under Regulatory T Cell Cover to Induce Donor-Specific Tolerance.

scientific article published in February 2017

CD3bright signals on γδ T cells identify IL-17A-producing Vγ6Vδ1+ T cells

scientific article published on 11 November 2014

CD4+ natural regulatory T cells prevent experimental cerebral malaria via CTLA-4 when expanded in vivo

scientific article

CD8α+ DCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3.

scientific article

CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease.

scientific article

Chronic graft-versus-host disease after granulocyte colony-stimulating factor-mobilized allogeneic stem cell transplantation: the role of donor T-cell dose and differentiation.

scientific article published in June 2004

Chronic graft-versus-host disease: biological insights from preclinical and clinical studies

scientific article published on 7 November 2016

Clinical assessment of anti-viral CD8+ T cell immune monitoring using QuantiFERON-CMV® assay to identify high risk allogeneic hematopoietic stem cell transplant patients with CMV infection complications

scientific article published on 11 October 2013

Coinfection with Human Cytomegalovirus Genetic Variants in Transplant Recipients and Its Impact on Antiviral T Cell Immune Reconstitution

scientific article published on 8 June 2016

Combination antithymocyte globulin and soluble TNFα inhibitor (etanercept) +/− mycophenolate mofetil for treatment of steroid refractory acute graft-versus-host disease

scientific article published on 08 May 2006

Common strategies to prevent and modulate experimental cerebral malaria in mouse strains with different susceptibilities

scientific article

Conditioning regimens for autologous haematopoietic stem cell transplantation - can natural killer cell therapy help?

scientific article published on 17 February 2017

Conventional dendritic cells are the critical donor APC presenting alloantigen after experimental bone marrow transplantation

scientific article published on 31 March 2009

Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD.

scientific article published on 23 June 2016

CpG pretreatment enhances antiviral T-cell immunity against cytomegalovirus

scientific article published on 14 May 2013

Critical roles for LIGHT and its receptors in generating T cell-mediated immunity during Leishmania donovani infection

scientific article

Cross-Dressing by Donor Dendritic Cells after Allogeneic Bone Marrow Transplantation Contributes to Formation of the Immunological Synapse and Maximizes Responses to Indirectly Presented Antigen

article

Cytokine Dysregulation in Acute Graft-versus-Host Disease

scientific article

Cytokine cascades in acute graft-versus-host disease

scientific article published on August 1997

Cytokine mediators of chronic graft-versus-host disease

scientific article published on 30 June 2017

Cytokines in Graft-versus-Host Disease

scientific article

Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera

scientific article published on 13 March 2013

Disseminated varicella infection caused by varicella vaccine strain in a child with low invariant natural killer T cells and diminished CD1d expression.

scientific article

Donor Treatment with a Multipegylated G-CSF Maximizes Graft-versus-Leukemia Effects

scientific article published on 01 January 2009

Donor colonic CD103+ dendritic cells determine the severity of acute graft-versus-host disease.

scientific article published on 13 July 2015

Donor pretreatment with progenipoietin-1 is superior to granulocyte colony-stimulating factor in preventing graft-versus-host disease after allogeneic stem cell transplantation

scientific article published on 17 October 2002

Donor treatment with pegylated G-CSF augments the generation of IL-10-producing regulatory T cells and promotes transplantation tolerance.

scientific article published on 15 January 2004

Effector and regulatory T-cell function is differentially regulated by RelB within antigen-presenting cells during GVHD

scientific article published on 27 February 2007

Eomesodermin promotes the development of type 1 regulatory T (TR1) cells.

scientific article

Expansion of donor-reactive host T cells in primary graft failure after allogeneic hematopoietic SCT following reduced-intensity conditioning

scientific article published on 9 September 2013

Experiences and unmet needs of family members requested to donate haematopoietic stem cells to an ill relative: findings from a prospective multi-centre study

scientific article published on 18 May 2020

Functional Reconstitution of Natural Killer Cells in Allogeneic Hematopoietic Stem Cell Transplantation

scientific article

G-CSF MODULATES CYTOKINE PROFILE OF DENDRITIC CELLS AND DECREASES ACUTE GRAFT-VERSUS-HOST DISEASE THROUGH EFFECTS ON THE DONOR RATHER THAN THE RECIPIENT

scientific article published on 01 February 2000

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity.

scientific article published on 07 December 2016

Granulocyte-colony stimulating factor increases CD123hi blood dendritic cells with altered CD62L and CCR7 expression

scientific article published on 24 October 2002

Heat shock protein 10 inhibits lipopolysaccharide-induced inflammatory mediator production

scientific article

Host B cells produce IL-10 following TBI and attenuate acute GVHD after allogeneic bone marrow transplantation

scientific article published on 20 June 2006

IFN differentially controls the development of idiopathic pneumonia syndrome and GVHD of the gastrointestinal tract

article

IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection

scientific article

IL-11 separates graft-versus-leukemia effects from graft-versus-host disease after bone marrow transplantation.

scientific article

IL-17A-Producing γδ T Cells Suppress Early Control of Parasite Growth by Monocytes in the Liver.

scientific article published on 4 November 2015

IL-23 suppresses innate immune response independently of IL-17A during carcinogenesis and metastasis

scientific article

IL-6 promotes CD4+ T-cell and B-cell activation during Plasmodium infection.

scientific article

Ibrutinib treatment ameliorates murine chronic graft-versus-host disease

scientific article

Identification and expansion of highly suppressive CD8(+)FoxP3(+) regulatory T cells after experimental allogeneic bone marrow transplantation.

scientific article

Imaging the immunological synapse between dendritic cells and T cells.

scientific article published on 9 May 2015

Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets

scientific article published on 13 March 2012

Immune responses in multiple myeloma: role of the natural immune surveillance and potential of immunotherapies

scientific article

Immune-mediated mechanisms of parasite tissue sequestration during experimental cerebral malaria

scientific article published on 18 August 2010

Immunosurveillance and therapy of multiple myeloma are CD226 dependent

scientific article published on 15 June 2015

Immunotherapy following relapse of acute leukaemia after T-cell-replete allogeneic peripheral blood progenitor cell transplantation: importance of new onset chronic graft-versus-host disease

scientific article published on 25 September 2013

Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation

scientific article published on 7 September 2011

Impact of cytokine gene polymorphisms on graft-vs-host disease.

scientific article published on 29 September 2008

Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans

scientific article

Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo.

scientific article published on 11 October 2013

Induction of natural killer T cell-dependent alloreactivity by administration of granulocyte colony-stimulating factor after bone marrow transplantation

scientific article published on 29 March 2009

Inflammation and bone marrow transplantation

scientific article published on January 2009

Innate immunity defines the capacity of antiviral T cells to limit persistent infection

scientific article

Interferon γ-dependent migration of microglial cells in the retina after systemic cytomegalovirus infection.

scientific article

Interleukin-11 promotes T cell polarization and prevents acute graft-versus-host disease after allogeneic bone marrow transplantation.

scientific article published on July 1998

Interleukin-6 Modulates Graft-versus-Host Responses after Experimental Allogeneic Bone Marrow Transplantation ⬇️

scientific article published on November 3, 2010

Invariant natural killer T cell-natural killer cell interactions dictate transplantation outcome after alpha-galactosylceramide administration

scientific article published on 15 April 2009

Jak2V617F driven myeloproliferative neoplasm occurs independently of interleukin-3 receptor beta common signaling

scientific article published on 20 November 2015

Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation

scientific article

Modification of T cell responses by stem cell mobilization requires direct signaling of the T cell by G-CSF and IL-10

scientific article

Mouse models of bone marrow transplantation

scientific article published on January 2008

NK cells require IL-28R for optimal in vivo activity

scientific article published on 21 April 2015

NKT cell-dependent leukemia eradication following stem cell mobilization with potent G-CSF analogs.

scientific article

Novel platform technology for modular mucosal vaccine that protects against streptococcus.

scientific article published on 15 December 2016

Origin of Langerhans cells in normal skin and chronic GVHD after hematopoietic stem-cell transplantation

scientific article published on 01 January 2014

PD-1 dependent exhaustion of CD8+ T cells drives chronic malaria.

scientific article

PRETRANSPLANT CHEMOTHERAPY REDUCES INFLAMMATORY CYTOKINE PRODUCTION AND ACUTE GRAFT-VERSUS-HOST DISEASE AFTER ALLOGENEIC BONE MARROW TRANSPLANTATION

article

Pharmacokinetics and immunological outcomes of alemtuzumab-based treatment for steroid-refractory acute GvHD.

scientific article

Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-β production

scientific article

Post transplant CMV-specific T-cell immune reconstitution in the absence of global T-cell immunity is associated with a high risk of subsequent virus reactivation

scientific article published on 17 November 2014

Predicting survival for myeloid leukemia after HLA-identical sibling donor allogeneic stem cell transplantation

scientific article published on 01 February 2005

Promoting regulation via the inhibition of DNAM-1 after transplantation

scientific article published on 21 February 2013

Pulmonary hypertension as a consequence of alveolar capillary plugging by malignant megakaryocytes in essential thrombocythaemia

scientific article published on 01 December 1996

Recent insights to the mechanisms of graft-versus-host disease.

scientific article

Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease

scientific article

Reduced mucosal associated invariant T-cells are associated with increased disease severity and Pseudomonas aeruginosa infection in cystic fibrosis.

scientific article

Relapsed Plasma Cell Leukaemia Presenting with Aggressive Extramedullary Plasmacytomas in the Meninges and Testis--A Missed Opportunity for Induction CNS Prophylaxis

scientific article published on 01 April 2002

SOCS3 regulates graft-versus-host disease

scientific article

Small-molecule BCL6 inhibitor effectively treats mice with non-sclerodermatous chronic graft-versus-host disease

article

Soluble lymphotoxin is an important effector molecule in GVHD and GVL.

scientific article published on 29 September 2009

Spatiotemporal Characterization of the Cellular and Molecular Contributors to Liver Fibrosis in a Murine Hepatotoxic-Injury Model.

scientific article published on 4 January 2016

Stem cell mobilization with G-CSF analogs: a rational approach to separate GVHD and GVL?

scientific article

Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma

scientific article published on 30 April 2010

Strain-specific antibody therapy prevents cytomegalovirus reactivation after transplantation

scientific article

Successful immunotherapy of HCMV disease using virus-specific T cells expanded from an allogeneic stem cell transplant recipient.

scientific article

TGF- in allogeneic stem cell transplantation: friend or foe?

scientific article published on 07 June 2005

TRAIL+ NK cells control CD4+ T cell responses during chronic viral infection to limit autoimmunity.

scientific article published on October 2014

TUMOR NECROSIS FACTOR-?? NEUTRALIZATION REDUCES LUNG INJURY AFTER EXPERIMENTAL ALLOGENEIC BONE MARROW TRANSPLANTATION1

article

Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.

scientific article published on 16 March 2016

Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease

scientific article published on 7 April 2015

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects.

scientific article published on 23 July 2015

Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy

scientific article

Th17 plasticity and transition toward a pathogenic cytokine signature are regulated by cyclosporine after allogeneic SCT

scientific article published on 26 January 2017

The IL-17 Differentiation Pathway and Its Role in Transplant Outcome ⬇️

scientific article published on January 1, 2012

The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells

scientific article published on 17 February 2017

The early monocytic response to cytomegalovirus infection is MyD88 dependent but occurs independently of common inflammatory cytokine signals

scientific article published on 16 December 2013

The interferon-dependent orchestration of innate and adaptive immunity after transplantation

scientific article published on 18 April 2012

The use of low dose Orgaran in heparin-induced thrombocytopenia associated with in vitro platelet aggregation at higher Orgaran concentrations ⬇️

scientific article published on June 1, 1997

Therapeutic glucocorticoid-induced TNF receptor-mediated amplification of CD4+ T cell responses enhances antiparasitic immunity

scientific article published on 5 February 2010

Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner

scientific article published on 6 July 2016

Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy

scientific article published on 11 December 2012

Twenty-four hour continuous infusion of amphotericin B for the treatment of suspected or proven fungal infection in haematology patients

scientific article published in June 2005

Type I IFN signaling in CD8- DCs impairs Th1-dependent malaria immunity

scientific article

Type I interferons suppress CD4⁺ T-cell-dependent parasite control during blood-stage Plasmodium infection

scientific article published on 8 August 2011

Type I-IFNs control GVHD and GVL responses after transplantation

article

UVB-induced melanocyte proliferation in neonatal mice driven by CCR2-independent recruitment of Ly6c(low)MHCII(hi) macrophages

scientific article published on 15 January 2013

VCAM-1 and VLA-4 modulate dendritic cell IL-12p40 production in experimental visceral leishmaniasis

scientific article

Vaccinating donors to improve GVL ⬇️

scientific article published on November 24, 2011

α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice

scientific article published on 4 March 2015

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