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List of works by John D. Lipscomb

6-phenylpyrrolocytosine as a fluorescent probe to examine nucleotide flipping catalyzed by a DNA repair protein

scientific article published on 24 October 2020

A Long-Lived Fe(III)-(Hydroperoxo) Intermediate in the Active H200C Variant of Homoprotocatechuate 2,3-Dioxygenase: Characterization by Mössbauer, Electron Paramagnetic Resonance, and Density Functional Theory Methods.

scientific article

A Role of the Putidaredoxin COOH-terminus in P -450 cam (Cytochrome m ) Hydroxylations ⬇️

scientific article published on October 1, 1974

A hyperactive cobalt-substituted extradiol-cleaving catechol dioxygenase

scientific article

A two-electron-shell game: intermediates of the extradiol-cleaving catechol dioxygenases

scientific article published on 11 March 2014

Active-site structure of a β-hydroxylase in antibiotic biosynthesis

scientific article

Allosteric Control of O2 Reactivity in Rieske Oxygenases

scientific article published on 01 May 2005

An Fe2IVO2 Diamond Core Structure for the Key Intermediate Q of Methane Monooxygenase

scientific article published in Science

An unusual peroxo intermediate of the arylamine oxygenase of the chloramphenicol biosynthetic pathway

scientific article published on 21 January 2015

Aromatic ring cleavage by homoprotocatechuate 2,3-dioxygenase: role of His200 in the kinetics of interconversion of reaction cycle intermediates

scientific article published in May 2005

Benzoate 1,2-dioxygenase from Pseudomonas putida: single turnover kinetics and regulation of a two-component Rieske dioxygenase

scientific article

Biochemical and spectroscopic studies on (S)-2-hydroxypropylphosphonic acid epoxidase: a novel mononuclear non-heme iron enzyme

scientific article published in October 2003

CD and MCD studies of the effects of component B variant binding on the biferrous active site of methane monooxygenase.

scientific article published on 16 July 2008

CYTOCHROME P-450***amSUBSTRATE AND EFFECTOR INTERACTIONS

scientific article published on 01 January 1973

Catalase (KatA) plays a role in protection against anaerobic nitric oxide in Pseudomonas aeruginosa

scientific article

Characterization of an O2 adduct of an active cobalt-substituted extradiol-cleaving catechol dioxygenase

scientific article

Cloning, overexpression, and mutagenesis of the gene for homoprotocatechuate 2,3-dioxygenase from Brevibacterium fuscum.

scientific article published on June 1997

CmlI N-Oxygenase Catalyzes the Final Three Steps in Chloramphenicol Biosynthesis without Dissociation of Intermediates

scientific article published on 20 August 2017

Conversion of extradiol aromatic ring-cleaving homoprotocatechuate 2,3-dioxygenase into an intradiol cleaving enzyme

scientific article published in October 2003

Crystal Structure and Resonance Raman Studies of Protocatechuate 3,4- Dioxygenase Complexed with 3,4-Dihydroxyphenylacetate, ⬇️

scientific article published on September 23, 1997

Crystal structure of CmlI, the arylamine oxygenase from the chloramphenicol biosynthetic pathway

scientific article published on 26 May 2016

Crystal structures of alkylperoxo and anhydride intermediates in an intradiol ring-cleaving dioxygenase.

scientific article

Crystal structures of substrate and substrate analog complexes of protocatechuate 3,4-dioxygenase: endogenous Fe3+ ligand displacement in response to substrate binding

scientific article

Cyanide and Nitric Oxide Binding to Reduced Protocatechuate 3,4-Dioxygenase: Insight into the Basis for Order-Dependent Ligand Binding by Intradiol Catecholic Dioxygenases ⬇️

scientific article published on November 18, 1997

Cyanobacterial aldehyde deformylase oxygenation of aldehydes yields n-1 aldehydes and alcohols in addition to alkanes

scientific article published on October 2013

Cytochrome P450 cam: SS- dimer and -SH derivative reactivities

scientific article published on August 1978

Desaturation reactions catalyzed by soluble methane monooxygenase

scientific article published in September 2001

Determination of the iron(IV) local spin states of the Q intermediate of soluble methane monooxygenase by Kβ X-ray emission spectroscopy

scientific article published in 2022

Determination of the quaternary structure of protocatechuate 3,4-dioxygenase from Pseudomonas aeruginosa

scientific article published on 01 May 1987

Determination of the substrate binding mode to the active site iron of (S)-2-hydroxypropylphosphonic acid epoxidase using 17O-enriched substrates and substrate analogues

scientific article

Diiron monooxygenases in natural product biosynthesis

scientific article published on 19 March 2018

ENDOR studies of the ligation and structure of the non-heme iron site in ACC oxidase

scientific article published in May 2005

Effector proteins from P450(cam) and methane monooxygenase: lessons in tuning nature's powerful reagents

scientific article published in December 2003

Electron paramagnetic resonance detection of intermediates in the enzymatic cycle of an extradiol dioxygenase

scientific article published on 8 October 2008

Enzyme Substrate Complex of the H200C Variant of Homoprotocatechuate 2,3-Dioxygenase: Mössbauer and Computational Studies

scientific article published on 08 June 2016

Equilibrating (L)FeIII-OOAc and (L)FeV(O) Species in Hydrocarbon Oxidations by Bio-Inspired Nonheme Iron Catalysts Using H2O2 and AcOH.

scientific article

Finding intermediates in the O2 activation pathways of non-heme iron oxygenases.

scientific article published on 14 June 2007

Gating Effects of Component B on Oxygen Activation by the Methane Monooxygenase Hydroxylase Component

scientific article published in Journal of Biological Chemistry

High-Energy-Resolution Fluorescence-Detected X-ray Absorption of the Q Intermediate of Soluble Methane Monooxygenase.

scientific article published on 14 November 2017

High-Resolution EXAFS Provides Evidence for a Longer Fe•••Fe Distance in the Q Intermediate of Methane Monooxygenase

article

Hydrogen peroxide sensitivity of catechol-2,3-dioxygenase: a cautionary note on use of xylE reporter fusions under aerobic conditions

scientific article published in September 2000

Hydrogen peroxide-coupled cis-diol formation catalyzed by naphthalene 1,2-dioxygenase

scientific article published on 25 October 2002

Intermediate P* from soluble methane monooxygenase contains a diferrous cluster

scientific article published on 13 June 2013

Intermediate Q from soluble methane monooxygenase hydroxylates the mechanistic substrate probe norcarane: evidence for a stepwise reaction

scientific article published in December 2001

Intermediate in the O−O Bond Cleavage Reaction of an Extradiol Dioxygenase † , ‡

scientific article

Key amino acid residues in the regulation of soluble methane monooxygenase catalysis by component B.

scientific article published in May 2003

Kinetics and Activation Thermodynamics of Methane Monooxygenase CompoundQFormation and Reaction with Substrates†

article

Large Kinetic Isotope Effects in Methane Oxidation Catalyzed by Methane Monooxygenase: Evidence for C−H Bond Cleavage in a Reaction Cycle Intermediate†

article

Life in a sea of oxygen.

scientific article

Mechanism for Six-Electron Aryl-N-Oxygenation by the Non-Heme Diiron Enzyme CmlI.

scientific article published on 20 May 2016

Mechanistic insights into C-H activation from radical clock chemistry: oxidation of substituted methylcyclopropanes catalyzed by soluble methane monooxygenase from Methylosinus trichosporium OB3b

scientific article

Mechanistic studies of 1-aminocyclopropane-1-carboxylic acid oxidase: single turnover reaction

scientific article

Methane monooxygenase component B mutants alter the kinetics of steps throughout the catalytic cycle

scientific article published in February 2001

Methane monooxygenase hydroxylase and B component interactions.

scientific article published in March 2006

Modulation of substrate binding to naphthalene 1,2-dioxygenase by rieske cluster reduction/oxidation

scientific article published in February 2003

Mössbauer and EPR spectroscopy of protocatechuate 3,4-dioxygenase from Pseudomonas aeruginosa

scientific article published on December 1976

NO binding to Mn-substituted homoprotocatechuate 2,3-dioxygenase: relationship to O₂ reactivity

scientific article published on 4 July 2013

NRVS Studies of the Peroxide Shunt Intermediate in a Rieske Dioxygenase and Its Relation to the Native FeII O2 Reaction.

scientific article published on 11 April 2018

Near-IR MCD of the nonheme ferrous active site in naphthalene 1,2-dioxygenase: correlation to crystallography and structural insight into the mechanism of Rieske dioxygenases

scientific article

Nuclear Resonance Vibrational Spectroscopy Definition of O2 Intermediates in an Extradiol Dioxygenase: Correlation to Crystallography and Reactivity

scientific article published on 26 November 2018

Oxy intermediates of homoprotocatechuate 2,3-dioxygenase: facile electron transfer between substrates

scientific article

Oxygen activation catalyzed by methane monooxygenase hydroxylase component: proton delivery during the O-O bond cleavage steps

scientific article published in April 1999

P-450cam hydroxylase: substrate-effector and electron-transport reactions

scientific article published on 01 December 1971

Preliminary Crystallographic Analysis of Methane Mono-oxygenase Hydroxylase from Methylosinus trichosporium OB3b

scientific article published on 01 February 1994

Preliminary Crystallographic Study of Protocatechuate 3,4-Dioxygenase from Brevibacterium fuscum

scientific article published on 01 February 1994

Protocatechuate 3,4-dioxygenase. Inhibitor studies and mechanistic implications

scientific article

Purification of a high specific activity methane monooxygenase hydroxylase component from a type II methanotroph

scientific article published on 01 July 1988

Radical intermediates in monooxygenase reactions of rieske dioxygenases

scientific article published on 7 March 2007

Radiolytic Reduction of Methane Monooxygenase Dinuclear Iron Cluster at 77 K

scientific article published in Journal of Biological Chemistry

Rate-Determining Attack on Substrate Precedes Rieske Cluster Oxidation during Cis-Dihydroxylation by Benzoate Dioxygenase

scientific article published on 21 July 2015

Regulation of methane monooxygenase catalysis based on size exclusion and quantum tunneling

scientific article published in February 2006

Residues inMethylosinus trichosporiumOB3b Methane Monooxygenase Component B Involved in Molecular Interactions with Reduced- and Oxidized-Hydroxylase Component: A Role for the N-Terminus†

article

Role of the C-terminal region of the B component of Methylosinus trichosporium OB3b methane monooxygenase in the regulation of oxygen activation

scientific article published in February 2006

Roles of the Methane Monooxygenase Reductase Component in the Regulation of Catalysis†

article

Roles of the equatorial tyrosyl iron ligand of protocatechuate 3,4-dioxygenase in catalysis

scientific article published in August 2005

Salicylate 5-Hydroxylase: Intermediates in Aromatic Hydroxylation by a Rieske Monooxygenase

scientific article published on 15 May 2019

Single-turnover kinetics of homoprotocatechuate 2,3-dioxygenase

scientific article published in December 2004

Site-directed mutagenesis and spectroscopic studies of the iron-binding site of (S)-2-hydroxypropylphosphonic acid epoxidase

scientific article

Spectroscopic and electronic structure studies of protocatechuate 3,4-dioxygenase: nature of tyrosinate-Fe(III) bonds and their contribution to reactivity

scientific article published in January 2002

Spectroscopic and electronic structure study of the enzyme-substrate complex of intradiol dioxygenases: substrate activation by a high-spin ferric non-heme iron site

scientific article published on 26 January 2007

Spectroscopic studies of 1-aminocyclopropane-1-carboxylic acid oxidase: molecular mechanism and CO(2) activation in the biosynthesis of ethylene

scientific article published in May 2002

Spectroscopic studies of the anaerobic enzyme-substrate complex of catechol 1,2-dioxygenase

scientific article

Spectroscopic studies of the effect of ligand donor strength on the Fe-NO bond intradiol dioxygenases.

scientific article published in January 2003

Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200

scientific article

Structural Basis for the Role of Tyrosine 257 of Homoprotocatechuate 2,3-Dioxygenase in Substrate and Oxygen Activation

scientific article

Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5)

scientific article

Structure of a Dinuclear Iron Cluster-Containing β-Hydroxylase Active in Antibiotic Biosynthesis

scientific article

Structure of the key species in the enzymatic oxidation of methane to methanol

scientific article published on 21 January 2015

Structures of Competitive Inhibitor Complexes of Protocatechuate 3,4-Dioxygenase: Multiple Exogenous Ligand Binding Orientations within the Active Site, ⬇️

scientific article published on August 19, 1997

Substrate binding to NO-ferro-naphthalene 1,2-dioxygenase studied by high-resolution Q-band pulsed 2H-ENDOR spectroscopy

scientific article

Substrate radical intermediates in soluble methane monooxygenase

scientific article published on 7 September 2005

Substrate-mediated oxygen activation by homoprotocatechuate 2,3-dioxygenase: intermediates formed by a tyrosine 257 variant.

scientific article

Superoxide anion production by the autoxidation of cytochrome P450cam

article

Swapping metals in Fe- and Mn-dependent dioxygenases: Evidence for oxygen activation without a change in metal redox state

scientific article

The axial tyrosinate Fe3+ ligand in protocatechuate 3,4-dioxygenase influences substrate binding and product release: evidence for new reaction cycle intermediates

scientific article

The magnetic susceptibility of reduced cytochrome P-450-cam

scientific article

Trapping and spectroscopic characterization of an FeIII-superoxo intermediate from a nonheme mononuclear iron-containing enzyme ⬇️

scientific article published on September 13, 2010

Two-pronged survival strategy for the major cystic fibrosis pathogen, Pseudomonas aeruginosa, lacking the capacity to degrade nitric oxide during anaerobic respiration.

scientific article

Unmasking of Deuterium Kinetic Isotope Effects on the Methane Monooxygenase Compound Q Reaction by Site-Directed Mutagenesis of Component B

scientific article published on 01 October 2001

Unprecedented (μ-1,1-Peroxo)diferric Structure for the Ambiphilic Orange Peroxo Intermediate of the Nonheme N-Oxygenase CmlI.

scientific article published on 4 July 2017

VTVH-MCD and DFT studies of thiolate bonding to [FeNO]7/[FeO2]8 complexes of isopenicillin N synthase: substrate determination of oxidase versus oxygenase activity in nonheme Fe enzymes

scientific article published on 17 May 2007

Versatility of biological non-heme Fe(II) centers in oxygen activation reactions.

scientific article published on March 2008

X-ray absorption spectroscopic studies of the Fe(II) active site of catechol 2,3-dioxygenase. Implications for the extradiol cleavage mechanism

article

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