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List of works by Budd A. Tucker

A Method for Sectioning and Immunohistochemical Analysis of Stem Cell-Derived 3-D Organoids

scientific article published on 12 May 2016

A procedure for selecting and culturing subpopulations of neurons from rat dorsal root ganglia using magnetic beads

scientific article published on 23 November 2005

ABCB5 is a limbal stem cell gene required for corneal development and repair

scientific article (publication date: 17 July 2014)

ASSESSMENT OF AAV SEROTYPE TROPISM IN HUMAN RETINAL EXPLANTS.

scientific article published on 21 November 2017

AUTOIMMUNE RETINOPATHY MIMICKING HERITABLE RETINAL DEGENERATION IN A PATIENT WITH COMMON VARIABLE IMMUNE DEFICIENCY

scientific article published on 21 November 2019

Allogenic iPSC-derived RPE cell transplants induce immune response in pigs: a pilot study

scientific article published on 3 July 2015

Autologous cell replacement: a noninvasive AI approach to clinical release testing

scientific article published on 01 February 2020

Basal exon skipping and genetic pleiotropy: A predictive model of disease pathogenesis

scientific article published on June 2015

CEP290 gene transfer rescues Leber congenital amaurosis cellular phenotype.

scientific article published on 8 May 2014

CNS progenitor cells promote a permissive environment for neurite outgrowth via a matrix metalloproteinase-2-dependent mechanism

scientific article published in April 2007

CRISPR-Cas9 genome engineering: Treating inherited retinal degeneration.

scientific article published on 22 March 2018

CRISPR-Cas9-Based Genome Editing of Human Induced Pluripotent Stem Cells

scientific article published on 28 February 2018

CRISPR-Cas9-Mediated Correction of the 1.02 kb Common Deletion in CLN3 in Induced Pluripotent Stem Cells from Patients with Batten Disease

scientific article published on 01 February 2018

Choriocapillaris Degeneration in Geographic Atrophy

scientific article published on 30 April 2019

Clinically Focused Molecular Investigation of 1000 Consecutive Families with Inherited Retinal Disease.

scientific article published on 27 May 2017

Combining chondroitinase ABC and growth factors promotes the integration of murine retinal progenitor cells transplanted into Rho(-/-) mice.

scientific article published on 29 June 2011

Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy.

scientific article

Concise Review: Patient-Specific Stem Cells to Interrogate Inherited Eye Disease

scientific article

Connective Tissue Growth Factor Promotes Efficient Generation of Human Induced Pluripotent Stem Cell-Derived Choroidal Endothelium

scientific article published on 5 May 2017

Controlled drug delivery from 3D printed two-photon polymerized poly(ethylene glycol) dimethacrylate devices ⬇️

scientific article published on 27 September 2018

Correction of NR2E3 Associated Enhanced S-cone Syndrome Patient-specific iPSCs using CRISPR-Cas9.

scientific article published on 5 April 2019

Correction: Transplantation of Adult Mouse iPS Cell-Derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice

scientific article published on 7 May 2015

Correlation of Optical Coherence Tomography and Retinal Histology in Normal and Pro23His Retinal Degeneration Pig

scientific article published on 30 November 2018

Development of High-Resolution Three-Dimensional-Printed Extracellular Matrix Scaffolds and Their Compatibility with Pluripotent Stem Cells and Early Retinal Cells

scientific article published on 16 August 2019

Development of a Molecularly Stable Gene Therapy Vector for the Treatment of RPGR-Associated X-Linked Retinitis Pigmentosa

scientific article published on 01 August 2019

Differentiation of Induced Pluripotent Stem Cells to Neural Retinal Precursor Cells on Porous Poly-Lactic-co-Glycolic Acid Scaffolds.

scientific article published on 21 December 2015

Disruption of RPGR protein interaction network is the common feature of RPGR missense variations that cause XLRP

scientific article published on 08 January 2019

Duplication of TBK1 Stimulates Autophagy in iPSC-derived Retinal Cells from a Patient with Normal Tension Glaucoma

scientific article

Effect of Molecular Weight and Functionality on Acrylated Poly(caprolactone) for Stereolithography and Biomedical Applications

scientific article published on 09 August 2018

Elevated MMP Expression in the MRL Mouse Retina Creates a Permissive Environment for Retinal Regeneration

scientific article published on April 2008

Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors

scientific article

Endurance exercise regimens induce differential effects on brain-derived neurotrophic factor, synapsin-I and insulin-like growth factor I after focal ischemia

scientific article

Enhanced differentiation and delivery of mouse retinal progenitor cells using a micropatterned biodegradable thin-film polycaprolactone scaffold

scientific article published on 19 March 2015

Evaluation of sFLT1 protein levels in human eyes with the FLT1 rs9943922 polymorphism

scientific article

Evaluation of serum and ocular levels of membrane attack complex and C-reactive protein in CFH-genotyped human donors

scientific article published on 16 July 2018

Exercise intensity influences the temporal profile of growth factors involved in neuronal plasticity following focal ischemia

scientific article published on 2 March 2007

Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa

scientific article

Expression of the retina-specific flippase, ABCA4, in epidermal keratinocytes

Feeder-free differentiation of cells exhibiting characteristics of corneal endothelium from human induced pluripotent stem cells.

scientific article published on 23 April 2018

Gene therapy using stem cells

scientific article

Generating iPSC-Derived Choroidal Endothelial Cells to Study Age-Related Macular Degeneration

scientific article published on December 2015

Generation of Xeno-Free, cGMP-Compliant Patient-Specific iPSCs from Skin Biopsy

scientific article published on 14 August 2017

Generation of an immortalized human choroid endothelial cell line (iChEC-1) using an endothelial cell specific promoter

scientific article published on 18 December 2018

Growth kinetics and transplantation of human retinal progenitor cells.

scientific article

Hypomorphic mutations in TRNT1 cause retinitis pigmentosa with erythrocytic microcytosis.

scientific article

Imidazole Compounds for Protecting Choroidal Endothelial Cells from Complement Injury

scientific article published in Scientific Reports

Induction of trabecular meshwork cells from induced pluripotent stem cells

scientific article

Integrin activation and neurotrophin signaling cooperate to enhance neurite outgrowth in sensory neurons

scientific article published in June 2005

Is age-related macular degeneration a microvascular disease?

scientific article published on January 2014

Laminin and growth factor receptor activation stimulates differential growth responses in subpopulations of adult DRG neurons

scientific article published on August 2006

Loss of CD34 expression in aging human choriocapillaris endothelial cells

scientific article published on 21 January 2014

Low-oxygen culture conditions extend the multipotent properties of human retinal progenitor cells

scientific article published on 24 January 2014

Mechanical properties of murine and porcine ocular tissues in compression

scientific article published on 05 March 2014

Molecular response of chorioretinal endothelial cells to complement injury: implications for macular degeneration

scientific article published on 13 November 2015

Monomeric C-reactive protein and inflammation in age-related macular degeneration

scientific article published on 4 July 2016

Müller cell activation, proliferation and migration following laser injury

scientific article

Natural history of cone disease in the murine model of Leber congenital amaurosis due to CEP290 mutation: determining the timing and expectation of therapy

scientific article

Neuronal Differentiation of Induced Pluripotent Stem Cells on Surfactant Templated Chitosan Hydrogels.

scientific article published on 23 March 2016

Non-exomic and synonymous variants in ABCA4 are an important cause of Stargardt disease.

scientific article published on 04 August 2013

North Carolina Macular Dystrophy Is Caused by Dysregulation of the Retinal Transcription Factor PRDM13.

scientific article

Optimizing Donor Cellular Dissociation and Subretinal Injection Parameters for Stem Cell-Based Treatments

scientific article published on 19 April 2019

Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa

scientific article published on 27 August 2013

Patient-specific induced pluripotent stem cells (iPSCs) for the study and treatment of retinal degenerative diseases

scientific article

Patient-specific induced pluripotent stem cells to evaluate the pathophysiology of TRNT1-associated Retinitis pigmentosa

scientific article published on 18 March 2017

Peripheral sensory axon growth: from receptor binding to cellular signaling

scientific article

Pharmacokinetics of intravitreal glial cell line-derived neurotrophic factor: experimental studies in pigs.

scientific article published on 29 September 2010

Photoreceptor cells with profound structural deficits can support useful vision in mice

scientific article published on 25 March 2014

Preparation and evaluation of human choroid extracellular matrix scaffolds for the study of cell replacement strategies.

scientific article published on 5 May 2017

Preservation of biological activity of glial cell line-derived neurotrophic factor (GDNF) after microencapsulation and sterilization by gamma irradiation.

scientific article

Prevascularized silicon membranes for the enhancement of transport to implanted medical devices.

scientific article published on 28 August 2015

PyMINEr Finds Gene and Autocrine-Paracrine Networks from Human Islet scRNA-Seq ⬇️

article

Restoration of Aqueous Humor Outflow Following Transplantation of iPSC-Derived Trabecular Meshwork Cells in a Transgenic Mouse Model of Glaucoma.

scientific article published in April 2017

Retinal Pigment Epithelium and Müller Progenitor Cell Interaction Increase Müller Progenitor Cell Expression of PDGFRα and Ability to Induce Proliferative Vitreoretinopathy in a Rabbit Model

scientific article published on 23 August 2012

Retinal ganglion cells survival in a glaucoma model by GDNF/Vit E PLGA microspheres prepared according to a novel microencapsulation procedure.

scientific article published on 24 June 2011

Robust cell integration from co-transplantation of biodegradable MMP2-PLGA microspheres with retinal progenitor cells.

scientific article published on 28 October 2010

Selective accumulation of the complement membrane attack complex in aging choriocapillaris

scientific article published on 11 September 2015

Single-Cell RNA Sequencing in Human Retinal Degeneration Reveals Distinct Glial Cell Populations

scientific article published on 13 February 2020

Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration

scientific article published on 11 November 2019

Src and FAK are key early signalling intermediates required for neurite growth in NGF-responsive adult DRG neurons

scientific article published on 18 October 2007

Stem cells as tools for studying the genetics of inherited retinal degenerations

scientific article published on 11 December 2014

Stem cells for investigation and treatment of inherited retinal disease

scientific article published on 18 March 2014

Stem cells in large animal models of retinal and neurological disease

scientific article published on 10 May 2012

Structural and biochemical analyses of choroidal thickness in human donor eyes.

scientific article published on 06 March 2014

Structural and molecular changes in the aging choroid: implications for age-related macular degeneration

scientific article

The membrane attack complex in aging human choriocapillaris: relationship to macular degeneration and choroidal thinning

scientific article

The synergistic effects of NGF and IGF-1 on neurite growth in adult sensory neurons: convergence on the PI 3-kinase signaling pathway.

scientific article published in September 2003

The use of progenitor cell/biodegradable MMP2-PLGA polymer constructs to enhance cellular integration and retinal repopulation

scientific article published on 22 September 2009

Transcriptomic analysis across nasal, temporal, and macular regions of human neural retina and RPE/choroid by RNA-Seq

scientific article

Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice

scientific article

Transplantation of iPSC-derived TM cells rescues glaucoma phenotypes in vivo.

scientific article published on 06 June 2016

Two-Photon Polymerization as a Tool for Studying 3D Printed Topography-Induced Stem Cell Fate

scientific article published on 14 November 2018

Two-photon polymerization for production of human iPSC-derived retinal cell grafts.

scientific article published on 25 March 2017

Two-photon polymerized poly(caprolactone) retinal cell delivery scaffolds and their systemic and retinal biocompatibility

scientific article published on 03 May 2019

Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation

scientific article

Using CRISPR-Cas9 to Generate Gene-Corrected Autologous iPSCs for the Treatment of Inherited Retinal Degeneration

scientific article published on 12 June 2017

Using Patient-Specific Induced Pluripotent Stem Cells and Wild-Type Mice to Develop a Gene Augmentation-Based Strategy to Treat CLN3-Associated Retinal Degeneration

scientific article published on 11 July 2016

Using Stem Cells to Rebuild the Outer Neural Retina

scientific article published on 01 June 2016

Using patient-specific induced pluripotent stem cells to interrogate the pathogenicity of a novel retinal pigment epithelium-specific 65 kDa cryptic splice site mutation and confirm eligibility for enrollment into a clinical gene augmentation trial

scientific article

Wide-Field Swept-Source OCT and Angiography in X-Linked Retinoschisis

scientific article published on 19 September 2018

cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness

scientific article published on 29 July 2016

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