List of works - Peter G Zaphiropoulos

A Map of the MouseCyp3aLocus ⬇️

scientific article published on 01 June 2003

A dual role of growth hormone as a feminizing and masculinizing factor in the control of sex-specific cytochrome P-450 isozymes in rat liver

scientific article published on 01 February 1989

A mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalities

scientific article

A novel first exon of the Patched1 gene is upregulated by Hedgehog signaling resulting in a protein with pathway inhibitory functions

scientific article

A statistical view of genome transcription?

scientific article published on 01 August 2001

Alternative first exons of PTCH1 are differentially regulated in vivo and may confer different functions to the PTCH1 protein

scientific article

An updated h-index measures both the primary and total scientific output of a researcher

scientific article

Blockade of the Hedgehog pathway downregulates estrogen receptor alpha signaling in breast cancer cells.

scientific article published on 26 September 2016

Cloning and pretranslational hormonal regulation of testosterone 16 alpha-hydroxylase (P-45016 alpha) in male rat liver.

scientific article

Cytochrome P450 genes expressed in porcine ovaries: identification of novel forms, evidence for gene conversion, and evolutionary relationships

scientific article

Differential expression of cytochrome P450 2C24 transcripts in rat kidney and prostate: evidence indicative of alternative and possibly trans splicing events

scientific article published in April 1993

Distinct roles of PTCH2 splice variants in Hedgehog signalling

scientific article

Distinct roles of first exon variants of the tumor-suppressor Patched1 in Hedgehog signaling

scientific article published on 19 February 2007

Gene structure and expression of the rat cytochrome P450IIC13, a polymorphic, male-specific cytochrome in the P450IIC subfamily ⬇️

scientific article published on November 12, 1991

Genetic instability of microsatellite markers in region q22.3-q31 of chromosome 9 in skin squamous cell carcinomas

scientific article

Genetic variations and alternative splicing: the Glioma associated oncogene 1, GLI1 ⬇️

scientific article published on 06 July 2012

Genetic variations regulate alternative splicing in the 5' untranslated regions of the mouse glioma-associated oncogene 1, Gli1.

scientific article

Growth hormone regulation of the cytochrome P-450IIC subfamily in the rat: inductive, repressive, and transcriptional effects on P-450f (IIC7) and P-450PB1 (IIC6) gene expression

scientific article

Hormonal Regulation of Cytochrome P-450 Gene Expression

scientific article published on January 1, 1991

Human patched (PTCH) mRNA is overexpressed consistently in tumor cells of both familial and sporadic basal cell carcinoma.

scientific article published on June 1997

Identification and localization of cytochromes P450 expressed in brain.

scientific article

Identification of cytochrome P450 in extrahepatic tissues by cross-hybridization of oligonucleotides and cDNAs.

scientific article

Identification of novel GLI1 target genes and regulatory circuits in human cancer cells

scientific article published on 30 August 2018

Identification of novel non-coding RNA-based negative feedback regulating the expression of the oncogenic transcription factor GLI1.

scientific article published on 22 March 2014

Identification of the major cytochrome P450s of subfamily 2C that are expressed in brain of female rats and in olfactory lobes of ethanol treated male rats

scientific article published in June 1993

Intergenic mRNA Molecules Resulting fromtrans-Splicing ⬇️

scientific article published on November 28, 2001

Intergenic mRNAs. Minor gene products or tools of diversity?

scientific article

Intergenic transcripts containing a novel human cytochrome P450 2C exon 1 spliced to sequences from the CYP2C9 gene

scientific article published on October 2001

Isolation and characterization of a novel cytochrome P-450-like pseudogene

scientific article published in January 1986

Lack of aneuploidy for chromosomes 15, 16, and 18 in placentas from small-for-gestational-age liveborn infants

scientific article published on 13 November 2007

Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1

scientific article

Mechanisms of pre-mRNA splicing: classical versus non-classical pathways

scientific article published on 01 April 1998

Mutation analysis of the human homologue ofdrosophila patched and the xeroderma pigmentosum complementation group A genes in squamous cell carcinomas of the skin ⬇️

scientific article published on February 1, 1998

Mutations in the human homologue of Drosophila patched (PTCH) in basal cell carcinomas and the Gorlin syndrome: different in vivo mechanisms of PTCH inactivation

scientific article

Neighboring gene regulation by antisense long non-coding RNAs

scientific article

Non-homologous recombination mediated by Thermus aquaticus DNA polymerase I. Evidence supporting a copy choice mechanism ⬇️

scientific article published on June 15, 1998

Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal

scientific article published on 31 March 2008

Novel mechanism of action on Hedgehog signaling by a suppressor of fused carboxy terminal variant

scientific article

PTCH mutations: distribution and analyses

scientific article

PTCH1 gene mutations in exon 17 and loss of heterozygosity on D9S180 microsatellite in sporadic and inherited human basal cell carcinomas.

scientific article

Patched 2, located in 1p32-34, is not mutated in high stage neuroblastoma tumors

scientific article published in May 2000

RITA downregulates Hedgehog-GLI in medulloblastoma and rhabdomyosarcoma via JNK-dependent but p53-independent mechanism

scientific article published on 14 November 2018

RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling

scientific article published on 16 January 2013

RNA molecules containing exons originating from different members of the cytochrome P450 2C gene subfamily (CYP2C) in human epidermis and liver

scientific article

Reduction of human embryonal rhabdomyosarcoma tumor growth by inhibition of the hedgehog signaling pathway

scientific article published on September 2010

Regulation of sexual differentiation in drug and steroid metabolism

scientific article

Sequence and regulation of two growth-hormone-controlled, sex-specific isozymes of cytochrome P-450 in rat liver, P-450(15)beta and P-450(16)alpha

scientific article published on 01 January 1988

Structural and regulatory analysis of a cytochrome P450 gene (CYP2C12) expressed predominantly in female rat liver

scientific article published on 01 January 1990

Tamoxifen Resistance: Emerging Molecular Targets

scientific article

Tamoxifen Treatment of Breast Cancer Cells: Impact on Hedgehog/GLI1 Signaling.

scientific article published on 27 February 2016

Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo

scientific article published on 3 October 2012

Template switching generated during reverse transcription?

scientific article published in September 2002

The FU gene and its possible protein isoforms

scientific article

The impact of S6K1 kinase on neuroblastoma cell proliferation is independent of GLI1 signaling

scientific article

The kidney cytochrome P-450 2C23 arachidonic acid epoxygenase is upregulated during dietary salt loading.

scientific article

The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas

scientific article

Trans-splicing in Higher Eukaryotes: Implications for Cancer Development? ⬇️

scientific article published on December 26, 2011

Transcriptional regulation of rat P-450 2C gene subfamily members by the sexually dimorphic pattern of growth hormone secretion

scientific article published on February 1992

cDNA cloning and initial characterization of CYP3A43, a novel human cytochrome P450

scientific journal article

cDNA cloning, sequence, and regulation of a major female-specific and growth hormone-inducible rat liver cytochrome P-450 active in 15 beta-hydroxylation of steroid sulfates.

scientific article

List of works by Peter G Zaphiropoulos

A Map of the MouseCyp3aLocus ⬇️

A dual role of growth hormone as a feminizing and masculinizing factor in the control of sex-specific cytochrome P-450 isozymes in rat liver

A mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalities

A novel first exon of the Patched1 gene is upregulated by Hedgehog signaling resulting in a protein with pathway inhibitory functions

A statistical view of genome transcription?

Alternative first exons of PTCH1 are differentially regulated in vivo and may confer different functions to the PTCH1 protein

An updated h-index measures both the primary and total scientific output of a researcher

Blockade of the Hedgehog pathway downregulates estrogen receptor alpha signaling in breast cancer cells.

Cloning and pretranslational hormonal regulation of testosterone 16 alpha-hydroxylase (P-45016 alpha) in male rat liver.

Cytochrome P450 genes expressed in porcine ovaries: identification of novel forms, evidence for gene conversion, and evolutionary relationships

Differential expression of cytochrome P450 2C24 transcripts in rat kidney and prostate: evidence indicative of alternative and possibly trans splicing events

Distinct roles of PTCH2 splice variants in Hedgehog signalling

Distinct roles of first exon variants of the tumor-suppressor Patched1 in Hedgehog signaling

Gene structure and expression of the rat cytochrome P450IIC13, a polymorphic, male-specific cytochrome in the P450IIC subfamily ⬇️

Genetic instability of microsatellite markers in region q22.3-q31 of chromosome 9 in skin squamous cell carcinomas

Genetic variations and alternative splicing: the Glioma associated oncogene 1, GLI1 ⬇️

Genetic variations regulate alternative splicing in the 5' untranslated regions of the mouse glioma-associated oncogene 1, Gli1.

Growth hormone regulation of the cytochrome P-450IIC subfamily in the rat: inductive, repressive, and transcriptional effects on P-450f (IIC7) and P-450PB1 (IIC6) gene expression

Hormonal Regulation of Cytochrome P-450 Gene Expression

Human patched (PTCH) mRNA is overexpressed consistently in tumor cells of both familial and sporadic basal cell carcinoma.

Identification and localization of cytochromes P450 expressed in brain.

Identification of cytochrome P450 in extrahepatic tissues by cross-hybridization of oligonucleotides and cDNAs.

Identification of novel GLI1 target genes and regulatory circuits in human cancer cells

Identification of novel non-coding RNA-based negative feedback regulating the expression of the oncogenic transcription factor GLI1.

Identification of the major cytochrome P450s of subfamily 2C that are expressed in brain of female rats and in olfactory lobes of ethanol treated male rats

Intergenic mRNA Molecules Resulting fromtrans-Splicing ⬇️

Intergenic mRNAs. Minor gene products or tools of diversity?

Intergenic transcripts containing a novel human cytochrome P450 2C exon 1 spliced to sequences from the CYP2C9 gene

Isolation and characterization of a novel cytochrome P-450-like pseudogene

Lack of aneuploidy for chromosomes 15, 16, and 18 in placentas from small-for-gestational-age liveborn infants

Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1

Mechanisms of pre-mRNA splicing: classical versus non-classical pathways

Mutation analysis of the human homologue ofdrosophila patched and the xeroderma pigmentosum complementation group A genes in squamous cell carcinomas of the skin ⬇️

Mutations in the human homologue of Drosophila patched (PTCH) in basal cell carcinomas and the Gorlin syndrome: different in vivo mechanisms of PTCH inactivation

Neighboring gene regulation by antisense long non-coding RNAs

Non-homologous recombination mediated by Thermus aquaticus DNA polymerase I. Evidence supporting a copy choice mechanism ⬇️

Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal

Novel mechanism of action on Hedgehog signaling by a suppressor of fused carboxy terminal variant

PTCH mutations: distribution and analyses

PTCH1 gene mutations in exon 17 and loss of heterozygosity on D9S180 microsatellite in sporadic and inherited human basal cell carcinomas.

Patched 2, located in 1p32-34, is not mutated in high stage neuroblastoma tumors

RITA downregulates Hedgehog-GLI in medulloblastoma and rhabdomyosarcoma via JNK-dependent but p53-independent mechanism

RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling

RNA molecules containing exons originating from different members of the cytochrome P450 2C gene subfamily (CYP2C) in human epidermis and liver

Reduction of human embryonal rhabdomyosarcoma tumor growth by inhibition of the hedgehog signaling pathway

Regulation of sexual differentiation in drug and steroid metabolism

Sequence and regulation of two growth-hormone-controlled, sex-specific isozymes of cytochrome P-450 in rat liver, P-450(15)beta and P-450(16)alpha

Structural and regulatory analysis of a cytochrome P450 gene (CYP2C12) expressed predominantly in female rat liver

Tamoxifen Resistance: Emerging Molecular Targets

Tamoxifen Treatment of Breast Cancer Cells: Impact on Hedgehog/GLI1 Signaling.

Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo

Template switching generated during reverse transcription?

The FU gene and its possible protein isoforms

The impact of S6K1 kinase on neuroblastoma cell proliferation is independent of GLI1 signaling

The kidney cytochrome P-450 2C23 arachidonic acid epoxygenase is upregulated during dietary salt loading.

The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas

Trans-splicing in Higher Eukaryotes: Implications for Cancer Development? ⬇️

Transcriptional regulation of rat P-450 2C gene subfamily members by the sexually dimorphic pattern of growth hormone secretion

cDNA cloning and initial characterization of CYP3A43, a novel human cytochrome P450

cDNA cloning, sequence, and regulation of a major female-specific and growth hormone-inducible rat liver cytochrome P-450 active in 15 beta-hydroxylation of steroid sulfates.