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List of works by William Matsui

A DNA hypermethylation module for the stem/progenitor cell signature of cancer.

scientific article published on 5 March 2012

A bis-benzylidine piperidone targeting proteasome ubiquitin receptor RPN13/ADRM1 as a therapy for cancer

scientific article published on December 2013

A combination of DR5 agonistic monoclonal antibody with gemcitabine targets pancreatic cancer stem cells and results in long-term disease control in human pancreatic cancer model.

scientific article published on 26 July 2010

A direct pancreatic cancer xenograft model as a platform for cancer stem cell therapeutic development.

scientific article

Achaete-scute complex homologue 1 regulates tumor-initiating capacity in human small cell lung cancer.

scientific article

Activated marrow-infiltrating lymphocytes effectively target plasma cells and their clonogenic precursors

scientific article published on 01 March 2005

Activation of liver X receptors inhibits hedgehog signaling, clonogenic growth, and self-renewal in multiple myeloma

scientific article published on 7 May 2014

Allogeneic Blood or Marrow Transplantation with Post-Transplantation Cyclophosphamide as Graft-versus-Host Disease Prophylaxis in Multiple Myeloma

scientific article published on 12 July 2017

An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer.

scientific article published on September 2008

Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma

scientific article published on 21 February 2019

Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma.

scientific article published on 19 April 2018

Anti-tumour activity of interferon-alpha in multiple myeloma: role of interleukin 6 and tumor cell differentiation

scientific article published on 01 April 2003

Associations between serum folate and vitamin D levels and incident mouse sensitization in adults

scientific article

Autologous stem cell transplantation and multiple myeloma cancer stem cells.

scientific article published on January 2012

Biological and clinical relevance of stem cells in pancreatic adenocarcinoma

scientific article published on March 2012

Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers

scientific article

Brief intensive therapy for older adults with newly diagnosed Burkitt or atypical Burkitt lymphoma/leukemia ⬇️

scientific article published on August 17, 2012

Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma

scientific article

Cancer Stem Cells: From Bench to Bedside

scientific article published on January 2007

Cancer stem cells in lung cancer: Evidence and controversies.

scientific article published on July 2013

Cancer stem cells in multiple myeloma.

scientific article published on 21 September 2008

Cancer stem cells: relevance to clinical transplantation

scientific article

Cancer-Related Epigenome Changes Associated with Reprogramming to Induced Pluripotent Stem Cells ⬇️

scientific article published on September 14, 2010

Characterization of clonogenic multiple myeloma cells

scientific article

Chloroquine Improves Survival and Hematopoietic Recovery After Lethal Low-Dose-Rate Radiation ⬇️

scientific article published on March 22, 2012

Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance

scientific article

Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models ⬇️

scientific article published on October 1, 2011

Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma

scientific article (publication date: October 2007)

DCLK1 marks a morphologically distinct subpopulation of cells with stem cell properties in preinvasive pancreatic cancer

scientific article published on 2 October 2013

DNER, an epigenetically modulated gene, regulates glioblastoma-derived neurosphere cell differentiation and tumor propagation.

scientific article

Development and maintenance of cancer stem cells under chronic inflammation

scientific article published on January 2011

Differentiation of a highly tumorigenic basal cell compartment in urothelial carcinoma.

scientific article

Differentiation therapy in poor risk myeloid malignancies: Results of a dose finding study of the combination bryostatin-1 and GM-CSF.

scientific article

Do neoplastic stem cells underlie the pathogenesis of cutaneous lymphomas?

scientific article published on 01 May 2005

Early Fever after Haploidentical Bone Marrow Transplantation Correlates with Class II HLA-Mismatching and Myeloablation but Not Outcomes

scientific article published on 15 June 2018

Effects of imatinib and interferon on primitive chronic myeloid leukaemia progenitors

scientific article

Enhanced cytotoxicity of rituximab following genetic and biochemical disruption of glycosylphosphatidylinositol anchored proteins

scientific article published on April 2004

GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein.

scientific article published on 03 February 2009

Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors.

scientific article

Glucocorticoid receptor transcriptional activity determined by spacing of receptor and nonreceptor DNA sites

scientific article published on November 1998

Graft-versus-host reactions and the effectiveness of donor lymphocyte infusions

scientific article published on 01 April 2006

Granulocyte-macrophage colony stimulating factor (GM-CSF) enhances the clinical responses to interferon-α (IFN) in newly diagnosed chronic myeloid leukemia (CML).

scientific article

Growth differentiating factor 15 enhances the tumor-initiating and self-renewal potential of multiple myeloma cells.

scientific article published on 17 December 2013

High-dose cyclophosphamide and rituximab without stem cell transplant: a feasibility study for low grade B-cell, transformed and mantle cell lymphomas

scientific article

High-dose cyclophosphamide as single-agent, short-course prophylaxis of graft-versus-host disease.

scientific article

High-dose cyclophosphamide for severe aplastic anemia: long-term follow-up

scientific article

Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres

scientific article

Immunologic recovery following autologous stem-cell transplantation with pre- and posttransplantation rituximab for low-grade or mantle cell lymphoma.

scientific article

Induction of acute lymphocytic leukemia differentiation by maintenance therapy

scientific article published on 05 July 2007

Induction of autologous graft-versus-host disease: results of a randomized prospective clinical trial in patients with poor risk lymphoma.

scientific article published on 3 August 2007

Isolation of stem cells from human pancreatic cancer xenografts

scientific article

Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer

scientific article

Molecular Pathways: The Hedgehog Signaling Pathway in Cancer ⬇️

scientific article published on June 19, 2012

NRF2-mediated Notch pathway activation enhances hematopoietic reconstitution following myelosuppressive radiation.

scientific article published on 27 January 2014

Nonmyeloablative HLA-haploidentical bone marrow transplantation with high-dose posttransplantation cyclophosphamide: effect of HLA disparity on outcome

scientific article

Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors

scientific article published in August 2006

Perspective: A model disease ⬇️

scientific article published on December 14, 2011

Phase 2 study of rituximab-ABVD in classical Hodgkin lymphoma.

scientific article

Prognostic significance of tumorigenic cells with mesenchymal features in pancreatic adenocarcinoma

scientific article

Quantitative analysis of bone marrow CD34 cells in aplastic anemia and hypoplastic myelodysplastic syndromes

scientific article published on 01 March 2006

Relationships between folate and inflammatory features of asthma ⬇️

scientific article published on December 11, 2012

Requirement for myeloid growth factors in the differentiation of acute promyelocytic leukaemia.

scientific article published on March 2005

Salvage transplantation for allograft failure using fludarabine and alemtuzumab as conditioning regimen.

scientific article

Self-renewal of acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926

scientific article (publication date: 28 December 2010)

Smoothening the controversial role of hedgehog in hematopoiesis

scientific article published on June 2009

Targeting Hedgehog--a cancer stem cell pathway

scientific article

Telomerase inhibition targets clonogenic multiple myeloma cells through telomere length-dependent and independent mechanisms

scientific article

The extracellular matrix and focal adhesion kinase signaling regulate cancer stem cell function in pancreatic ductal adenocarcinoma

scientific article published on 10 July 2017

The gamma secretase inhibitor MRK-003 attenuates pancreatic cancer growth in preclinical models

scientific article

The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity.

scientific article

The redox-sensitive transcription factor Nrf2 regulates murine hematopoietic stem cell survival independently of ROS levels.

scientific article published on 28 October 2011

Tumor-initiating capacity of CD138- and CD138+ tumor cells in the 5T33 multiple myeloma model

scientific article published on 6 January 2012

Tumor-initiating cells are rare in many human tumors

scientific article

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