List of works by Alexander W. Tarr

A Diverse Panel of Hepatitis C Virus Glycoproteins for Use in Vaccine Research Reveals Extremes of Monoclonal Antibody Neutralization Resistance.

scientific article published on 23 December 2015

An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission

scientific article

Analysis of serine codon conservation reveals diverse phenotypic constraints on hepatitis C virus glycoprotein evolution

scientific article (publication date: 2014)

Analysis of the binding of hepatitis C virus genotype 1a and 1b E2 glycoproteins to peripheral blood mononuclear cell subsets

scientific article published on September 2005

Association of antibodies to hepatitis C virus glycoproteins 1 and 2 (anti-E1E2) with HCV disease.

scientific article published on 22 January 2008

B-cell receptors expressed by lymphomas of hepatitis C virus (HCV)-infected patients rarely react with the viral proteins

scientific article published on 21 January 2014

Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge

scientific article published on 6 December 2007

Characterization of host-range and cell entry properties of the major genotypes and subtypes of hepatitis C virus

scientific article (publication date: February 2005)

Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33.

scientific article

Cloning and Analysis of Authentic Patient-Derived HCV E1/E2 Glycoproteins

scientific article published on 01 January 2019

Cloning, expression, and functional analysis of patient-derived hepatitis C virus glycoproteins.

scientific article published on January 2007

Colicin import into E. coli cells: a model system for insights into the import mechanisms of bacteriocins

scientific article

Cross-genotype AR3-specific neutralizing antibodies confer long-term protection in injecting drug users after HCV clearance

scientific article published on 21 February 2019

Cross-genotype characterization of genetic diversity and molecular adaptation in hepatitis C virus envelope glycoprotein genes

scientific article published in February 2007

Determination of the human antibody response to the epitope defined by the hepatitis C virus-neutralizing monoclonal antibody AP33.

scientific article

Dramatic potentiation of the antiviral activity of HIV antibodies by cholesterol conjugation

scientific article

Elevated serum activity of MBL and ficolin-2 as biomarkers for progression to hepatocellular carcinoma in chronic HCV infection

scientific article published on 12 February 2019

Enhanced nanoparticle uptake into virus infected cells: Could nanoparticles be useful in antiviral therapy?

scientific article published on 13 June 2018

Enterovirus D68 epidemic, UK, 2018, was caused by subclades B3 and D1, predominantly in children and adults, respectively, with both subclades exhibiting extensive genetic diversity

scientific article published on 09 May 2022

Entry inhibition of HSV-1 and -2 protects mice from viral lethal challenge

scientific article published on 7 April 2017

Evolutionary dynamics of hepatitis C virus envelope genes during chronic infection.

scientific article published in July 2005

Expression of human ficolin-2 in hepatocytes confers resistance to infection by diverse hepatotropic viruses

scientific article published on 12 February 2019

Flexible and rapid construction of viral chimeras applied to hepatitis C virus.

scientific article published on 21 June 2016

Functional and immunogenic characterization of diverse HCV glycoprotein E2 variants

scientific article published on 13 November 2018

Genetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine Design

scientific article

Hepatitis C Virus Vaccine: Challenges and Prospects

scientific article published on 17 February 2020

Hepatitis C patient-derived glycoproteins exhibit marked differences in susceptibility to serum neutralizing antibodies: genetic subtype defines antigenic but not neutralization serotype.

scientific article

Hepatitis C virus envelope glycoprotein fitness defines virus population composition following transmission to a new host

scientific article

Hepatitis C virus quasispecies and pseudotype analysis from acute infection to chronicity in HIV-1 co-infected individuals

scientific article published on 10 March 2016

High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end-stage liver disease. ⬇️

scientific article

Human Bocavirus infection and respiratory tract disease identified in a UK patient cohort

scientific article published on 21 May 2020

Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus

scientific article

Human lectins and their roles in viral infections.

scientific article

Human parainfluenza 2 & 4: Clinical and genetic epidemiology in the UK, 2013–2017, reveals distinct disease features and co‐circulating genomic subtypes

scientific article published in 2022

Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding

scientific article

Identification of New Functional Regions in Hepatitis C Virus Envelope Glycoprotein E2

scientific article

Identification of a Broadly Cross-Reacting and Neutralizing Human Monoclonal Antibody Directed against the Hepatitis C Virus E2 Protein

scientific article

Immunization with a synthetic consensus hepatitis C virus E2 glycoprotein ectodomain elicits virus-neutralizing antibodies

scientific article published on 11 September 2018

InFusion Cloning for the Generation of Biologically Relevant HCV Chimeric Molecular Clones

scientific article published on 01 January 2019

Monoclonal Antibody AP33 Defines a Broadly Neutralizing Epitope on the Hepatitis C Virus E2 Envelope Glycoprotein

scientific article

Naturally occurring antibodies that recognize linear epitopes in the amino terminus of the hepatitis C virus E2 protein confer noninterfering, additive neutralization

scientific article (publication date: March 2012)

Non-ionic detergents facilitate non-specific binding of M13 bacteriophage to polystyrene surfaces.

scientific article published on 27 April 2015

Novel functional hepatitis C virus glycoprotein isolates identified using an optimized viral pseudotype entry assay.

scientific article published on 6 July 2016

Perceptions and Experiences of the University of Nottingham Pilot SARS-CoV-2 Asymptomatic Testing Service: A Mixed-Methods Study

scientific article published on 29 December 2020

Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy

scientific article published on 10 November 2020

Recombinant human L-ficolin directly neutralizes hepatitis C virus entry.

scientific article published on 15 May 2014

Specific interaction of hepatitis C virus glycoproteins with mannan binding lectin inhibits virus entry.

scientific article published on 29 July 2010

Structural and antigenic definition of hepatitis C virus E2 glycoprotein epitopes targeted by monoclonal antibodies

scientific article published on 09 July 2013

Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein E2 recognized by broadly neutralizing antibodies.

scientific article

Tagged polymerase chain reaction subtractive hybridization for the enrichment of phage display random peptide libraries.

scientific article

Technical considerations for the generation of novel pseudotyped viruses

The HCV Envelope Glycoprotein Down-Modulates NF-κB Signalling and Associates With Stimulation of the Host Endoplasmic Reticulum Stress Pathway

scientific article published on 15 March 2022

The P body protein LSm1 contributes to stimulation of hepatitis C virus translation, but not replication, by microRNA-122

scientific article published on 18 October 2013

The past, present and future of neutralizing antibodies for hepatitis C virus

scientific article published on 26 February 2014

The role of humoral innate immunity in hepatitis C virus infection.

scientific article published on 05 January 2012

The role of neutralizing antibodies in hepatitis C virus infection.

scientific article

Type I interferon rapidly restricts infectious hepatitis C virus particle genesis.

scientific article

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