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List of works by William MacNee

"Haemoxygenase-1 induction and exhaled markers of oxidative stress in lung diseases", summary of the ERS Research Seminar in Budapest, Hungary, September, 1999.

scientific article

4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease

scientific article published in August 2002

A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluation

scientific article published on 19 March 2012

A comparison of the effects of almitrine or oxygen breathing on pulmonary arterial pressure and right ventricular ejection fraction in hypoxic chronic bronchitis and emphysema

scientific article published on 01 September 1986

A comparison of three methods of measuring 99m Tc-DTPA lung clearance and their repeatability

scientific article published on 01 May 1998

A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13.

scientific article published on 11 November 2011

A guide to guidelines for professional societies and other developers of recommendations: introduction to integrating and coordinating efforts in COPD guideline development. An official ATS/ERS workshop report

scientific article published on December 2012

A review of the most common patient-reported outcomes in COPD--revisiting current knowledge and estimating future challenges

scientific article

A vision statement on guideline development for respiratory disease: the example of COPD.

scientific article published on 3 October 2008

AUTHORS' REPLY

scientific article published in February 1995

Abnormal lung aging in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

scientific article published on 10 May 2012

Accelerated lung aging: a novel pathogenic mechanism of chronic obstructive pulmonary disease (COPD).

scientific article published on August 2009

Activated human peripheral blood neutrophils produce epithelial injury and fibronectin breakdown in vitro

scientific article published in February 1992

Activation of NF-κB by PM10 Occurs via an Iron-Mediated Mechanism in the Absence of IκB Degradation

scientific article published on 01 July 2000

Acute exacerbations of COPD.

scientific article

Adenoviral E1A primes alveolar epithelial cells to PM(10)-induced transcription of interleukin-8.

scientific article

Adverse cardiovascular effects of air pollution

scientific article

Adverse health effects of PM10 particles: involvement of iron in generation of hydroxyl radical.

scientific article published on December 1996

Ageing and the border between health and disease

scientific article

Aging, Inflammation, and Emphysema ⬇️

scientific article published on December 15, 2011

Airway Infection Does Not Accelerate Decline in Lung Function in Chronic Obstructive Pulmonary Disease ⬇️

scientific article published on November 15, 2001

Airway dimensions in COPD: Relationships with clinical variables

article

Airways inflammation and treatment during acute exacerbations of COPD.

scientific article published on January 2008

Alcohol and cor pulmonale in chronic bronchitis and emphysema

scientific article

Allergic rhinitis, asthma, airway biology, and chronic obstructive pulmonary disease in AJRCCM in 2004.

scientific article

Aluminium lactate treatment of DQ12 quartz inhibits its ability to cause inflammation, chemokine expression, and nuclear factor-kappaB activation.

scientific article

Ambient particle inhalation and the cardiovascular system: potential mechanisms

scientific article

An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease

scientific article published on April 2015

An investigation of the role of glutathione in increased epithelial permeability induced by cigarette smoke in vivo and in vitro

scientific article published on June 1994

An official American Thoracic Society/European Respiratory Society statement: research questions in COPD

scientific article

An official American Thoracic Society/European Respiratory Society statement: research questions in COPD.

scientific article published on April 2015

Anti-inflammatory effects of atorvastatin treatment in chronic obstructive pulmonary disease. A controlled pilot study

scientific article published in February 2015

Antioxidant pharmacological therapies for COPD.

scientific article published on 18 February 2012

Apocynin increases glutathione synthesis and activates AP-1 in alveolar epithelial cells

scientific article

Arterial stiffness is independently associated with emphysema severity in patients with chronic obstructive pulmonary disease

scientific article

Assessment of right ventricular function

scientific article published in January 1990

Association Between Interstitial Lung Abnormalities and All-Cause Mortality

scientific article published on February 2016

Association of MMP-2 polymorphisms with severe and very severe COPD: a case control study of MMPs-1, 9 and 12 in a European population

scientific article

Associations between COPD related manifestations: a cross-sectional study

scientific article

Asthma and PM10

scientific article

Atrial natriuretic peptide in stable and decompensated chronic obstructive pulmonary disease

scientific article published on July 1993

Attenuation of oxidant/antioxidant imbalance during treatment of exacerbations of chronic obstructive pulmonary disease ⬇️

scientific article published on June 1, 1997

Authors response. The chronic obstructive pulmonary disease (COPD) control panel: towards personalised medicine in COPD.

scientific article published in April 2013

Avaliação dos resultados nos ensaios clínicos na DPOC: Da função pulmonar aos marcadores biológicos

scientific article published on 01 July 2008

Bone attenuation on routine chest CT correlates with bone mineral density on DXA in patients with COPD.

scientific article published in November 2012

Brain Natriuretic Peptide Measurement in Patients With COPD and Cardiovascular Disease: Response

scholarly article by John D. Maclay & William MacNee published September 2013 in Chest

British Thoracic Society guidelines for home oxygen use in adults

scientific article published in June 2015

Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease

article

CT Measurements of Lung Density in Life Can Quantitate Distal Airspace Enlargement—An Essential Defining Feature of Human Emphysema

CT-measured bone attenuation in patients with chronic obstructive pulmonary disease: Relation to clinical features and outcomes ⬇️

scientific article published on June 1, 2013

Can right ventricular performance be assessed by equilibrium radionuclide ventriculography?

scientific article published on July 1983

Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study

scientific article (publication date: July 2008)

Cardiovascular disease in COPD: mechanisms

scientific article published on March 2013

Cardiovascular injury and repair in chronic obstructive pulmonary disease

scientific article published on December 2008

Cardiovascular risk in chronic obstructive pulmonary disease

scientific article published on September 2007

Cause of death in COPD: still an open question?

scientific article published on 01 February 1997

Changes in Body Composition in Patients with Chronic Obstructive Pulmonary Disease: Do They Influence Patient-Related Outcomes?

article

Changes in Forced Expiratory Volume in 1 Second over Time in COPD ⬇️

scientific article published on September 26, 2011

Changes in Neutrophil Deformability followingIn VitroSmoke Exposure: Mechanism and Protection

Changes in neutrophil morphology and morphometry following exposure to cigarette smoke

scientific article published on April 1992

Characterisation of COPD heterogeneity in the ECLIPSE cohort ⬇️

scientific article published on September 10, 2010

Characterisation of gamma-glutamylcysteine synthetase-heavy subunit promoter: a critical role for AP-1.

scientific article published in May 1998

Characteristics, stability and outcomes of the 2011 GOLD COPD groups in the ECLIPSE cohort

scientific article

Chest CT measures of muscle and adipose tissue in COPD: gender-based differences in content and in relationships with blood biomarkers

scientific article

Chronic Obstructive Pulmonary Disease and Cardiovascular Diseases: A “Vulnerable” Relationship

article

Chronic cough and sputum production are associated with worse clinical outcomes in stable asthma

scientific article published on 6 August 2013

Chronic obstructive pulmonary disease from science to the clinic: the role of glutathione in oxidant-antioxidant balance

scientific article published on October 1, 1997

Chronic obstructive pulmonary disease phenotypes: the future of COPD.

scientific article published on 3 June 2010

Cigarette Smoke and Ozone-Induced Epithelial Perturbation In Vivo and In Vitro

scientific article published on 01 March 1996

Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs

scientific article

Cigarette smoke disrupts VEGF165-VEGFR-2 receptor signaling complex in rat lungs and patients with COPD: morphological impact of VEGFR-2 inhibition

scientific article published on 16 December 2005

Cigarette smoke prevents apoptosis through inhibition of caspase activation and induces necrosis.

scientific article published on 14 May 2003

Cigarette smoke regulates VEGFR2-mediated survival signaling in rat lungs

scientific article

Cigarette smoke, glutathione metabolism and epithelial permeability in rat lungs

scientific article published on 01 May 1995

Clinic Practice Guidelines: More of the Same?

Clinical and prognostic heterogeneity of C and D GOLD groups

scientific article published in July 2015

Combination of erythromycin and dexamethasone improves corticosteroid sensitivity induced by CSE through inhibiting PI3K-δ/Akt pathway and increasing GR expression.

scientific article

Combustion-derived nanoparticles: a review of their toxicology following inhalation exposure

scientific article

Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease

scientific article

Comorbidities and systemic effects of chronic obstructive pulmonary disease

scientific article published on March 2014

Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort ⬇️

scientific article published on June 19, 2013

Computed tomographic emphysema distribution: relationship to clinical features in a cohort of smokers

scientific article published in October 2008

Continuous fat-free mass decline in COPD: fact or fiction?: TABLE 1

article

Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality

scientific article published on 28 January 2014

Critical care in AJRCCM 2004.

scientific article

Cryptic haplotypes ofSERPINA1confer susceptibility to chronic obstructive pulmonary disease

article

Cystic fibrosis, pediatrics, control of breathing, pulmonary physiology and anatomy, and surfactant biology in AJRCCM in 2004.

scientific article published in March 2005

Cytoplasm-nuclear trafficking of CREB and CREB phosphorylation at Ser133 during therapy of chronic obstructive pulmonary disease.

scientific article

Cytotoxicity and induction of inflammation by pepsin in Acid in bronchial epithelial cells

scientific article published on 12 July 2011

DIAGNOSIS OF PULMONARY EMPHYSEMA BY COMPUTERISED TOMOGRAPHY

scientific article published in The Lancet

Deciding what type of evidence and outcomes to include in guidelines: article 5 in Integrating and coordinating efforts in COPD guideline development. An official ATS/ERS workshop report

scientific article published on December 2012

Decreased Leukocyte Deformability after Acute Cigarette Smoking in Humans

article

Deformability and CD11/CD18 expression of sequestered neutrophils in normal and inflamed lungs

Diagnosis of myocardial infarction following hospitalisation for exacerbation of COPD

article

Diagnosis, assessment, and phenotyping of COPD: beyond FEV₁

scientific article

Diesel exhaust inhalation causes vascular dysfunction and impaired endogenous fibrinolysis

scientific article (publication date: 20 December 2005)

Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ions in vitro and in vivo; zinc and copper nanoparticles, but not their ions, recruit eosinophils to the lungs

scientific article published on 18 February 2011

Differential regulation of glutathione by oxidants and dexamethasone in alveolar epithelial cells

scientific article published on July 1998

Do inhaled carbon nanoparticles translocate directly into the circulation in humans?

scientific article

Does Cigarette Smoke Enhance the Proteolytic Activity of Neutrophils?

scientific article published on 01 January 1991

Effect of 6 Months of Erythromycin Treatment on Inflammatory Cells in Induced Sputum and Exacerbations in Chronic Obstructive Pulmonary Disease

article

Effect of N-acetyl cysteine on the concentrations of thiols in plasma, bronchoalveolar lavage fluid, and lung tissue.

scientific article published on July 1994

Effect of cigarette smoke and its condensates on alveolar epithelial cell injury in vitro

scientific article published on January 1994

Effectiveness of telemonitoring integrated into existing clinical services on hospital admission for exacerbation of chronic obstructive pulmonary disease: researcher blind, multicentre, randomised controlled trial

scientific article

Effects of inhalation of beta-sympathomimetic and atropine-like drugs on airway calibre in normal subjects

scientific article

Effects of lisinopril and amlodipine on antioxidant status in experimental hypertension

scientific article published on 01 September 2000

Effects of pirbuterol and sodium nitroprusside on pulmonary haemodynamics in hypoxic cor pulmonale

Efficacy and safety of the oral p38 inhibitor PH-797804 in chronic obstructive pulmonary disease: a randomised clinical trial.

scientific article published on 28 March 2013

Efficacy of simple short-term in vitro assays for predicting the potential of metal oxide nanoparticles to cause pulmonary inflammation

scientific article

Endothelial progenitor cells in patients with chronic obstructive pulmonary disease

scientific article published on 18 October 2013

Enhanced neutrophil response in chronic obstructive pulmonary disease

scientific article

Epithelial Permeability, Inflammation, and Oxidant Stress in the Air Spaces of Smokers

article

Erythrocyte and polymorphonuclear cell transit time and concentration in human pulmonary capillaries

scientific article published on 01 October 1994

Evaluating the role of inflammation in chronic airways disease: the ERICA study

scientific article

Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE)

article by Jørgen Vestbo et al published 1 April 2008 in European Respiratory Journal

Evaluation of emphysema progression as measured by computed tomography in patients with chronic obstructive pulmonary disease

scientific article published on 01 January 1996

Evaluation of exhaled breath condensate pH as a biomarker for COPD

article

Exacerbations of COPD: environmental mechanisms.

scientific article

Exploring the concept of need in people with very severe chronic obstructive pulmonary disease: a qualitative study.

scientific article published on 26 August 2015

Exposure to concentrated ambient particles does not affect vascular function in patients with coronary heart disease

scientific article published on June 2008

Expression of Adhesion Molecules and G Proteins in Circulating Neutrophils in Chronic Obstructive Pulmonary Disease

article

Expression of adhesion molecules during apoptosis of circulating neutrophils in COPD.

scientific article published on May 2004

Extent of pulmonary emphysema in man and its relation to the loss of elastic recoil

scientific article published on 01 April 1991

Factors affecting neutrophil transit during acute pulmonary inflammation: minireview

scientific article

Forced expiratory volume in one second predicts length of stay and in-hospital mortality in patients undergoing cardiac surgery: a retrospective cohort study

scientific article

Free radical activity and pro-inflammatory effects of particulate air pollution (PM10) in vivo and in vitro

scientific article

Free radical activity of PM10: iron-mediated generation of hydroxyl radicals

scientific article published on September 1997

Free radical activity of industrial fibers: role of iron in oxidative stress and activation of transcription factors

scientific article published on September 1997

Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD.

scientific article published on 9 July 2008

Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease

scientific article

Genome-wide mRNA expression profiling in vastus lateralis of COPD patients with low and normal fat free mass index and healthy controls

scientific article

Glutathione homeostasis in alveolar epithelial cells in vitro and lung in vivo under oxidative stress

scientific article

Glutathione prevents inhibition of fibroblast-mediated collagen gel contraction by cigarette smoke

scientific article published on August 2002

Graphene-based nanoplatelets: a new risk to the respiratory system as a consequence of their unusual aerodynamic properties.

scientific article published on 6 January 2012

Guidelines for chronic obstructive pulmonary disease

scientific article published on August 2004

HELPing older people with very severe chronic obstructive pulmonary disease (HELP-COPD): mixed-method feasibility pilot randomised controlled trial of a novel intervention

scientific article

Haplotypes of the alpha-1 antitrypsin gene in healthy controls and Z deficiency patients.

scientific article

Hemodynamic effects of ibopamine on the pulmonary circulation and right ventricular performance in patients with chronic obstructive pulmonary disease

scientific article published in January 1992

High-dose acetylcysteine in idiopathic pulmonary fibrosis

scientific article

Histone acetylation regulates epithelial IL-8 release mediated by oxidative stress from environmental particles

scientific article published on 22 November 2002

Human Models of Exacerbations of COPD

article

Hydrogen peroxide-induced epithelial injury: the protective role of intracellular nonprotein thiols (NPSH).

scientific article published on February 1998

Hypothesis: does COPD have an autoimmune component?

scientific article

Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis

scientific article published on March 2015

In vivo and in vitro proinflammatory effects of particulate air pollution (PM10).

scientific article

In vivo neutrophil sequestration within lungs of humans is determined by in vitro "filterability" ⬇️

scientific article published on November 1, 1991

Increased arterial stiffness in patients with chronic obstructive pulmonary disease: a mechanism for increased cardiovascular risk

scientific article published on 16 November 2007

Increased calcium influx in a monocytic cell line on exposure to ultrafine carbon black

scientific article

Increased platelet activation in patients with stable and acute exacerbation of COPD

scientific article published on 20 April 2011

Induction of γ-glutamylcysteine synthetase by cigarette smoke is associated with AP-1 in human alveolar epithelial cells

article

Inflammatory Biomarkers Improve Clinical Prediction of Mortality in Chronic Obstructive Pulmonary Disease

article

Inflammatory Lung Secretions Inhibit Dendritic Cell Maturation and Function via Neutrophil Elastase

article

Inhibition of neutrophil adherence and movement by acute cigarette smoke exposure

scientific article published on November 1992

Integrated care pathways for airway diseases (AIRWAYS-ICPs).

scientific article published on 12 June 2014

Interacting effects of particulate pollution and cold temperature on cardiorespiratory mortality in Scotland

scientific article published on 10 October 2007

Interstitial lung disease, lung cancer, lung transplantation, pulmonary vascular disorders, and sleep-disordered breathing in AJRCCM in 2004.

scientific article

Is oxidative stress central to the pathogenesis of chronic obstructive pulmonary disease?

scientific article published on February 2001

Is there any relationship between plasma antioxidant capacity and lung function in smokers and in patients with chronic obstructive pulmonary disease?

scientific article published on March 2000

Lack of systemic oxidative stress during PAF challenge in mild asthma

scientific article published on 21 November 2004

Length-dependent retention of carbon nanotubes in the pleural space of mice initiates sustained inflammation and progressive fibrosis on the parietal pleura

scientific article

Lessons from ECLIPSE: a review of COPD biomarkers

scientific article published on 05 December 2013

Lipopolysaccharide-induced Alveolar Epithelial Permeability

article

Living and dying with severe chronic obstructive pulmonary disease: multi-perspective longitudinal qualitative study

scientific article

Living and dying with severe chronic obstructive pulmonary disease: multi-perspective longitudinal qualitative study

scholarly article by H. Pinnock et al published 1 September 2011 in BMJ supportive & palliative care

Localization of γ-glutamylcysteine synthetase messenger rna expression in lungs of smokers and patients with chronic obstructive pulmonary disease

article

Low sputum MMP-9/TIMP ratio is associated with airway narrowing in smokers with asthma

scientific article published on 3 July 2014

Lung CT density correlates with measurements of airflow limitation and the diffusing capacity

scientific article published in February 1991

Lung function in idiopathic pulmonary fibrosis--extended analyses of the IFIGENIA trial

scientific article published on 27 October 2009

Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease.

scientific article

Lung research funding in the UK: the British Lung Foundation perspective

scientific article published in April 1998

Measurement of CT lung density in patients with chronic asthma

scientific article published on 01 November 1997

Mechanism of lung injury caused by PM10 and ultrafine particles with special reference to COPD

scientific article published on 01 May 2003

Mechanism of transient nocturnal hypoxemia in hypoxic chronic bronchitis and emphysema

scientific article published in December 1985

Mechanisms of cigarette smoke induced increased airspace permeability

scientific article published on May 1996

Metabolic profiling detects biomarkers of protein degradation in COPD patients

article

Metal oxide nanoparticles induce unique inflammatory footprints in the lung: important implications for nanoparticle testing

scientific article

Microscopic and macroscopic measurements of emphysema: relation to carbon monoxide gas transfer ⬇️

scientific article published on March 1, 1992

Molecular mechanism of the regulation of glutathione synthesis by tumor necrosis factor-alpha and dexamethasone in human alveolar epithelial cells

scientific article published on February 1999

Molecular mechanism of transforming growth factor (TGF)-beta1-induced glutathione depletion in alveolar epithelial cells. Involvement of AP-1/ARE and Fra-1

scientific article (publication date: 14 June 2002)

Multiple microscopic pulmonary arteriovenous connections in the lungs presenting as cyanosis

scientific article published on April 1985

Nacystelyn inhibits oxidant-mediated interleukin-8 expression and NF-kappaB nuclear binding in alveolar epithelial cells

scientific article

Nanoparticle carbon black driven DNA damage induces growth arrest and AP-1 and NFkappaB DNA binding in lung epithelial A549 cell line.

scientific article

Nanoparticle-driven DNA damage mimics irradiation-related carcinogenesis pathways.

scientific article

Nebulized Glutathione Induces Bronchoconstriction in Patients with Mild Asthma

article

Neurological and endocrinological disorders: orphans in chronic obstructive pulmonary disease

scientific article published on October 2011

Neuromuscular electrical stimulation prevents muscle function deterioration in exacerbated COPD: A pilot study

article

Neutrophil Kinetics in Normal and Emphysematous Regions of Human Lungs

scientific article published on 01 January 1991

Neutrophil Sequestration in Rat Lungs

scientific article published on 01 January 1991

Neutrophil Traffic Through the Lungs in Man

scientific article published on 01 January 1991

Neutrophil chemokines in bronchoalveolar lavage fluid and leukocyte-conditioned medium from nonsmokers and smokers

scientific article published on 01 November 1998

Neutrophil kinetics in the lungs.

scientific article published on August 1990

Neutrophil sequestration in lungs removed at surgery. The effect of microscopic emphysema

Neutrophil sequestration in rat lungs

scientific article published on June 1995

New opportunities for respiratory research in Europe: FP7

article published in 2006

New paradigms in the pathogenesis of chronic obstructive pulmonary disease I.

scientific article published on September 2009

New perspectives on basic mechanisms in lung disease. 2. Neutrophil traffic in the lungs: role of haemodynamics, cell adhesion, and deformability

scientific article

NiO and Co3O4 nanoparticles induce lung DTH-like responses and alveolar lipoproteinosis

scientific article published on 4 August 2011

Nitric oxide production, alveolar macrophages and type II alveolar epithelial cells in response to LPS in vivo and in vitro

article

N‐isobutyrylcysteine, a donor of systemic thiols, does not reduce the exacerbation rate in chronic bronchitis

scientific article published on 01 April 1999

One-year change in health status and subsequent outcomes in COPD.

scientific article published on 17 March 2015

Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report

scientific article

Oral antioxidant supplementation does not prevent acute mountain sickness: double blind, randomized placebo-controlled trial.

scientific article

Outcomes for COPD pharmacological trials: from lung function to biomarkers.

scientific article published on February 2008

Oxidant-mediated lung epithelial cell tolerance: the role of intracellular glutathione and nuclear factor-kappaB.

scientific article

Oxidant/antioxidant imbalance in smokers and chronic obstructive pulmonary disease

scientific article published on April 1996

Oxidants and COPD.

scientific article published on December 2005

Oxidants/antioxidants and chronic obstructive pulmonary disease: pathogenesis to therapy.

scientific article

Oxidative stress and TNF-alpha induce histone acetylation and NF-kappaB/AP-1 activation in alveolar epithelial cells: potential mechanism in gene transcription in lung inflammation

scientific article published on May 2002

Oxidative stress and adaptive response of glutathione in bronchial epithelial cells

scientific article published in April 2002

Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10).

scientific article

Oxidative stress and lung inflammation in airways disease.

scientific article

Oxidative stress and regulation of glutathione in lung inflammation

scientific article

PM(10)-exposed macrophages stimulate a proinflammatory response in lung epithelial cells via TNF-alpha

scientific article published on February 2002

Parenchymal emphysema measured by CT lung density correlates with lung function in patients with bullous disease

scientific article published on 01 May 1993

Particulate air pollution and acute health effects

scientific article (publication date: 21 January 1995)

Pathogenesis of Chronic Obstructive Pulmonary Disease

article

Pathogenesis of chronic obstructive pulmonary disease

article

Pathogenesis of chronic obstructive pulmonary disease. Cellular mechanisms (part I)

article

Pathogenesis of chronic obstructive pulmonary disease. Molecular mechanisms (part II)

article

Pathology, pathogenesis, and pathophysiology

scientific article

Pathophysiology of cor pulmonale in chronic obstructive pulmonary disease. Part One.

scientific article published on September 1994

Pathophysiology of cor pulmonale in chronic obstructive pulmonary disease. Part two.

scientific article published on October 1994

Permeability, inflammation and oxidant status in airspace epithelium exposed to ozone

article

Persistent Depletion of I Kappa B Alpha and Interleukin-8 Expression in Human Pulmonary Epithelial Cells Exposed to Quartz Particles

article

Persistent Systemic Inflammation is Associated with Poor Clinical Outcomes in COPD: A Novel Phenotype ⬇️

scientific article published on May 18, 2012

Persistent endothelial dysfunction in humans after diesel exhaust inhalation

scientific article

Piloting tele-monitoring in COPD: a mixed methods exploration of issues in design and implementation

scientific article published in March 2012

Poor symptom control is associated with reduced CT scan segmental airway lumen area in smokers with asthma

scientific article published on March 2015

Potential mechanisms of adverse pulmonary and cardiovascular effects of particulate air pollution (PM10).

scientific article

Potential role of IL-8, platelet-activating factor and TNF-alpha in the sequestration of neutrophils in the lung: effects on neutrophil deformability, adhesion receptor expression, and chemotaxis

scientific article published in February 2002

Predicting Outcomes from 6-Minute Walk Distance in Chronic Obstructive Pulmonary Disease ⬇️

scientific article published on July 21, 2011

Predictive value of in vitro assays depends on the mechanism of toxicity of metal oxide nanoparticles

scientific article

Predictors of Survival in Patients with Chronic Obstructive Pulmonary Disease Treated with Long-term Oxygen Therapy

article

Premature vascular ageing in cystic fibrosis

scholarly article by William MacNee published 30 November 2009 in European Respiratory Journal

Prescription of oxygen: still problems after all these years

scientific article published in September 2005

Priority setting in guideline development: article 2 in Integrating and coordinating efforts in COPD guideline development. An official ATS/ERS workshop report

scientific article published on December 2012

Prognostic value of variables derived from the six-minute walk test in patients with COPD: Results from the ECLIPSE study

scientific article

Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes.

scientific article

Proposal for a multidimensional staging system for chronic obstructive pulmonary disease

scientific article published in December 2005

Pulmonary Mycobacterium malmoense and aspergillus infection: a fatal combination?

scientific article published on May 1994

Pulmonary and systemic effects of short-term inhalation exposure to ultrafine carbon black particles

scientific article published in February 2004

Pulmonary and systemic oxidant/antioxidant imbalance in chronic obstructive pulmonary disease

scientific article

Pulmonary function is associated with distal aortic calcium, not proximal aortic distensibility. MESA lung study

scientific article published on April 2011

Pulmonary hypertension and right ventricular function in patients with COPD.

scientific article published in December 1988

Pulmonary neutrophil kinetics.

scientific article published on January 1990

Purpose of the Conference: 2015 Transatlantic Airway Conference

scientific article published on November 2015

Purpose of the conference

scientific article published in December 2013

Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study

scientific article

Randomised controlled trial for emphysema with a selective agonist of the γ-type retinoic acid receptor

scientific article

Regional pulmonary transit times in humans

scientific article

Regulation of LPS-mediated inflammation in vivo and in vitro by the thiol antioxidant Nacystelyn

scientific article published on June 2004

Regulation of iNOS expression and glutathione levels in rat liver by oxygen tension

article

Regulation of lipopolysaccharide-mediated interleukin-1beta release by N-acetylcysteine in THP-1 cells

scientific article

Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches.

scientific article

Reversal of hypoxia in a patient with chronic obstructive pulmonary disease, pulmonary hypertension, and oedema during treatment with long term domiciliary oxygen

scientific article published on May 1993

Rheological response of neutrophils to different types of stimulation

article

Right heart function in COPD.

scientific article published on 21 May 2010

Right ventricular function in cor pulmonale

scientific article published on January 1988

Right ventricular performance during exercise in chronic obstructive pulmonary disease. The effects of oxygen

scientific article

Role of inflammation in cardiopulmonary health effects of PM.

scientific article

Role of oxidants/antioxidants in smoking-induced lung diseases

scientific article published on January 1996

Role of transcription factors in inflammatory lung diseases

scientific article published in July 1998

Salbutamol reduces pulmonary neutrophil sequestration of platelet-activating factor in humans

scientific article published in August 1996

Serum PARC/CCL-18 concentrations and health outcomes in chronic obstructive pulmonary disease

scientific article

Should patients have cardiac catheterization prior to long-term oxygen treatment?

scientific article published on January 1990

Should we treat chronic obstructive pulmonary disease as a cardiovascular disease?

scientific article published on 18 July 2015

Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team

scientific article published in May 2014

Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization

scientific article published on 21 December 2012

Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines

scientific article

Socioeconomic deprivation increases the effect of winter on admissions to hospital with COPD: retrospective analysis of 10 years of national hospitalisation data.

scientific article

Soluble transition metals cause the pro-inflammatory effects of welding fumes in vitro

scientific article published on April 2004

Soluble transition metals in welding fumes cause inflammation via activation of NF-κB and AP-1

scientific article published on 21 April 2005

Sputum matrix metalloproteinase-12 in patients with chronic obstructive pulmonary disease and asthma: relationship to disease severity.

scientific article

Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper

scientific article (publication date: June 2004)

Surface derivatization state of polystyrene latex nanoparticles determines both their potency and their mechanism of causing human platelet aggregation in vitro

scientific article published on December 2010

Surface functionalization affects the zeta potential, coronal stability and membranolytic activity of polymeric nanoparticles

scientific article published on 28 May 2013

Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease ⬇️

scientific article published on September 16, 2010

Systemic Effect of Particulate Air Pollution

scholarly article by William MacNee et al published January 2000 in Inhalation Toxicology

Systemic and pulmonary oxidative stress in idiopathic pulmonary fibrosis

article

Systemic elastin degradation in chronic obstructive pulmonary disease

scientific article published on 28 February 2012

Systemic inflammatory biomarkers and co-morbidities of chronic obstructive pulmonary disease ⬇️

scientific article published on October 30, 2012

Systemic oxidative stress in asthma, COPD, and smokers

scholarly article by I Rahman et al published October 1996 in American Journal of Respiratory and Critical Care Medicine

Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease

scientific article published in October 2013

Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD

article

Targeted treatment in COPD: a multi-system approach for a multi-system disease

scientific article published on September 2009

Telomere shortening in smokers with and without COPD

scientific article published on 01 March 2006

The COPD control panel: towards personalised medicine in COPD.

scientific article

The Effect of Smoking on the Transcriptional Regulation of Lung Inflammation in Patients with Chronic Obstructive Pulmonary Disease

article

The European Respiratory Society spirometry tent: a unique form of screening for airway obstruction

scientific article published on 20 January 2012

The Pulmonary Toxicology of Ultrafine Particles

article

The SERPINE2 gene and chronic obstructive pulmonary disease.

scientific article published on July 2006

The Search for Distinct and Clinically Useful Phenotypes in Chronic Obstructive Pulmonary Disease

article

The adequacy of oxygenation in patients with hypoxic chronic obstructive pulmonary disease treated with long-term domiciliary oxygen

scientific article published on 01 May 1997

The chief scientist reports ... neutrophil traffic in human lungs

scientific article

The dependence of maximal flow in man on the airway gas physical properties

scientific article

The effect of cigarette smoking on neutrophil kinetics in human lungs

scientific article published on October 1989

The effect of lipocortin 1 on neutrophil deformability

scientific article published on January 1996

The effect of six months of daily treatment with the beta-2 agonist oral pirbuterol on pulmonary hemodynamics in patients with chronic hypoxic cor pulmonale receiving long-term oxygen therapy

scientific article

The effects of cigarette smoking on pulmonary hemodynamics

scientific article

The effects of controlled oxygen therapy on ventricular function in patients with stable and decompensated cor pulmonale

scientific article

The impact of a telemetric chronic obstructive pulmonary disease monitoring service: randomised controlled trial with economic evaluation and nested qualitative study.

scientific article published in September 2009

The potential impact of anaemia of chronic disease in COPD.

scientific article

The presence and progression of emphysema in COPD as determined by CT scanning and biomarker expression: a prospective analysis from the ECLIPSE study

scientific article published in February 2013

The pro-inflammatory effects of low-toxicity low-solubility particles, nanoparticles and fine particles, on epithelial cells in vitro: the role of surface area

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The procoagulant potential of environmental particles (PM10).

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The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study

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The role of oxidative stress in the prolonged inhibitory effect of ultrafine carbon black on epithelial cell function

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The role of tumor necrosis factor in increased airspace epithelial permeability in acute lung inflammation

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Transcriptional Regulation of γ-Glutamylcysteine Synthetase-Heavy Subunit by Oxidants in Human Alveolar Epithelial Cells

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Treatment of small cell carcinoma of the bronchus by combined chemotherapy--clinicopathological correlation with response

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Tuberculosis, nontuberculous lung infection, pleural disorders, pulmonary function, respiratory muscles, occupational lung disease, pulmonary infections, and social issues in AJRCCM in 2004

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Twenty-Ninth Transatlantic Airway Conference. Innate and adaptive immune responses in airway disease. Purpose of the conference

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Ultrafine Particle-Mediated Activation of Macrophages: Intracellular Calcium Signaling and Oxidative Stress

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Ultrafine carbon black particles inhibit human lung fibroblast-mediated collagen gel contraction

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Update in chronic obstructive pulmonary disease 2007.

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Update in chronic obstructive pulmonary disease 2008.

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Validation of Markers of Lung Destruction

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Validity of physical activity monitors during daily life in patients with COPD

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Variation in the tumour necrosis factor gene is not associated with susceptibility to COPD

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Vascular dysfunction in chronic obstructive pulmonary disease.

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Vitamin D, vitamin D binding protein, lung function and structure in COPD.

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Zeta potential and solubility to toxic ions as mechanisms of lung inflammation caused by metal/metal oxide nanoparticles

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