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List of works by Mark H. Kaplan

A conserved enhancer regulates Il9 expression in multiple lineages

scientific article published in Nature Communications

A gut reaction to IL-9.

scientific article published on July 2014

Altered STAT4 Isoform Expression in Patients with Inflammatory Bowel Disease.

scientific article

Altered cytokine production by dendritic cells from infants with atopic dermatitis ⬇️

scientific article published on September 29, 2010

An Inhibitory Role for the Transcription Factor Stat3 in Controlling IL-4 and Bcl6 Expression in Follicular Helper T Cells

scientific article published on 17 July 2015

Anti-STAT6 CTL activity in Stat6 (-/-) mice: A cautionary tale

scientific article published in April 2013

BATF-Interacting Proteins Dictate Specificity in Th Subset Activity

scientific article published on 26 August 2019

CD4+ T-cell-mediated anti-tumor immunity can be uncoupled from autoimmunity via the STAT4/STAT6 signaling axis

scientific article published on May 2009

Calcitriol Regulates the Differentiation of IL-9-Secreting Th9 Cells by Modulating the Transcription Factor PU.1.

scientific article published on 13 January 2020

Covalent Heterobivalent Inhibitor Design for Inhibition of IgE-Dependent Penicillin Allergy in a Murine Model

scientific article published on 17 May 2019

Differential requirement of signal transducer and activator of transcription-4 (Stat4) and Stat6 in a thyrotropin receptor-289-adenovirus-induced model of Graves' hyperthyroidism.

scientific article published on 29 September 2005

Distinct requirements for Stat4 and Stat6 in hematopoietic progenitor cell responses to growth factors and chemokines

scientific article published on 01 August 2003

Diverse inflammatory cytokines induce selectin ligand expression on murine CD4 T cells via p38α MAPK.

scientific article

Elevated IL-6 expression in CD4 T cells via PKCtheta and NF-kappaB induces Th2 cytokine production

scientific article published on 31 January 2009

Endonuclease and redox activities of human apurinic/apyrimidinic endonuclease 1 have distinctive and essential functions in IgA class switch recombination

scientific article published on 31 January 2019

Etv5 Regulates IL-10 Production in Th Cells

scientific article published on 18 January 2017

Expression Efficiency of Multiple Il9 Reporter Alleles Is Determined by Cell Lineage

scientific article published on 21 May 2020

Expression of a constitutively active Stat6 in vivo alters lymphocyte homeostasis with distinct effects in T and B cells

scientific article published on 01 April 2003

Gcn5 is required for PU.1-dependent IL-9 induction in Th9 cells.

scientific article

IL-9 by INFERence

scientific article published on October 2013

IRF4 Modulates CD8 T Cell Sensitivity to IL-2 Family Cytokines

scientific article published on 14 August 2017

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

scientific article published on July 1996

Impaired development of human Th1 cells in patients with deficient expression of STAT4.

scientific article published on 09 April 2009

Increased skin barrier disruption by sodium lauryl sulfate in mice expressing a constitutively active STAT6 in T cells.

scientific article published on 30 September 2011

Mast Cells Regulate Epidermal Barrier Function and the Development of Allergic Skin Inflammation.

scientific article published on 25 March 2016

Mechanism for Initiation of Food Allergy: Dependence on skin barrier mutations and environmental allergen co-stimulation.

scientific article published on 15 February 2018

Mouse pulmonary interstitial macrophages mediate the pro-tumorigenic effects of IL-9

scientific article published in 2022

Neonatal tolerance in the absence of Stat4- and Stat6- dependent Th cell differentiation

scientific article published on 01 October 2002

Opening the Black Box of Immunosuppression

scientific article published on 01 December 2018

Opposing Roles of STAT4 and Dnmt3a in Th1 Gene Regulation ⬇️

scientific article published on June 14, 2013

PARP14 limits severity of allergic skin disease

scientific article

PD-1hi CD8+ resident memory T cells balance immunity and fibrotic sequelae

scientific article published on 01 June 2019

PPAR-γ in Macrophages Limits Pulmonary Inflammation and Promotes Host Recovery following Respiratory Viral Infection

scientific article published on 17 April 2019

PU.1 Expression in T Follicular Helper Cells Limits CD40L-Dependent Germinal Center B Cell Development

scientific article published on 11 September 2015

PU.1 expression delineates heterogeneity in primary Th2 cells.

scientific article published in June 2005

Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production.

scientific article published on 3 May 2017

Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms

scientific article published on 25 April 2018

Predisposition to the development of IL-9–secreting T cells in atopic infants ⬇️

scientific article published on July 28, 2011

ResTORing barrier function in the skin

scientific article published on 22 October 2019

Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells

scientific article

Roles of T Follicular Helper Cells and T Follicular Regulatory Cells in Autoantibody Production in IL-2-Deficient Mice

scientific article published on 12 July 2019

STAT3 Activation Impairs the Stability of Th9 Cells

scientific article published on 30 January 2017

STAT3 Impairs STAT5 Activation in the Development of IL-9-Secreting T Cells

scientific article

STAT4 Regulates the CD8+ Regulatory T Cell/T Follicular Helper Cell Axis and Promotes Atherogenesis in Insulin-Resistant Ldlr-/- Mice.

scientific article published on 20 October 2017

STAT4 deficiency reduces the development of atherosclerosis in mice

scientific article

STAT4 is critical for immunity but not for antileishmanial activity of antimonials in experimental visceral leishmaniasis.

scientific article

STAT4 is required for IL-23 responsiveness in Th17 memory cells and NKT cells

scientific article

STAT4 requires the N-terminal domain for efficient phosphorylation

scientific article (publication date: 22 August 2003)

STAT4: a critical regulator of inflammation in vivo

scientific article

STAT5 promotes accessibility and is required for BATF-mediated plasticity at the Il9 locus

scientific article published on 28 September 2020

STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells

scientific article published on 28 September 2018

STAT6-Dependent Regulation of Th9 Development ⬇️

scientific article published on December 16, 2011

STAT6-mediated keratitis and blepharitis: a novel murine model of ocular atopic dermatitis

scientific article

Scratching the surface: towards understanding the pathogenesis of atopic dermatitis.

scientific article published on January 2008

Signal transducer and activator of transcription (Stat)-6-dependent, but not Stat4-dependent, immunity is required for the development of autoimmunity in Graves' hyperthyroidism

scientific article published on 29 April 2004

Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells

article

Specifically differentiated T cell subset promotes tumor immunity over fatal immunity.

scientific article published on 16 October 2017

Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation

scientific article published on 22 March 2007

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

scientific article published in March 1996

Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma.

scientific article published on February 2002

TH9 cells are required for tissue mast cell accumulation during allergic inflammation

scientific article

Th9 cell development requires a BATF-regulated transcriptional network

scientific article

Th9 cells: differentiation and disease.

scientific article published on March 2013

The ETS Family Transcription Factors Etv5 and PU.1 Function in Parallel To Promote Th9 Cell Development

scientific article published on 5 August 2016

The Il9 CNS-25 Regulatory Element Controls Mast Cell and Basophil IL-9 Production

scientific article published on 26 July 2019

The TNF-family ligand TL1A and its receptor DR3 promote T cell-mediated allergic immunopathology by enhancing differentiation and pathogenicity of IL-9-producing T cells.

scientific article published on 18 March 2015

The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections.

scientific article

The symphony of the ninth: the development and function of Th9 cells

scientific article published on 22 February 2012

The transcription factor Etv5 controls TH17 cell development and allergic airway inflammation.

scientific article

The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.

scientific article

The transcription factor PU.1 regulates γδ T cell homeostasis

scientific article

The transcription factor STAT3 is required for T helper 2 cell development

scientific article published on 6 January 2011

The transcription factor Twist1 limits T helper 17 and T follicular helper cell development by repressing the gene encoding the interleukin-6 receptor α chain.

scientific article published on 09 August 2013

The transcriptional repressor Bcl6 controls the stability of regulatory T cells by intrinsic and extrinsic pathways

scientific article published in May 2015

Tissue-resident CD4<sup>+</sup> T helper cells assist the development of protective respiratory B and CD8<sup>+</sup> T cell memory responses

scientific article published on 01 January 2021

Topical application of a vitamin D analogue exacerbates atopic dermatitis and induces the atopic dermatitis-like phenotype in Stat6VT mice.

scientific article published on 25 July 2013

Transcriptional regulation by STAT6.

scientific article published on May 2011

Twist1 regulates Ifng expression in Th1 cells by interfering with Runx3 function.

scientific article published on 8 June 2012

Yoking OX40 to regulation of IL-9.

scientific article published on October 2012

γδ T cell IFNγ production is directly subverted by Yersinia pseudotuberculosis outer protein YopJ in mice and humans

scientific article published on 06 December 2021

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