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List of works by Marc K. Jenkins

A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation

scientific article published on 15 August 2019

A germinal center–independent pathway generates unswitched memory B cells early in the primary response ⬇️

scientific article published on February 27, 2012

A monoclonal antibody specific for a cytochrome c T cell stimulatory peptide inhibits T cell responses and affects the way the peptide associates with antigen-presenting cells

scientific article published in January 1991

A natural immunological adjuvant enhances T cell clonal expansion through a CD28-dependent, interleukin (IL)-2-independent mechanism

scientific article published in January 1998

A protease-dependent mechanism for initiating T-dependent B cell responses to large particulate antigens

scientific article

A role for inflammatory cytokines in the productive activation of antigen-specific CD4+ T-cells ⬇️

scientific article published on January 1, 1998

A single amino acid substitution in a cytochrome c T cell stimulatory peptide changes the MHC restriction element from one isotype (I-Ak) to another (I-Ek)

scientific article published on 01 April 1993

Accessory cell-derived costimulatory signals regulate T cell proliferation

scientific article

Accessory cell-derived signals required for T cell activation

scientific article published on January 1993

Accumulation of Sequence-specific RNA-binding Proteins in the Cytosol of Activated T Cells Undergoing RNA Degradation and Apoptosis

scientific article published in Journal of Biological Chemistry

Adaptive Immunity to Leukemia Is Inhibited by Cross-Reactive Induced Regulatory T Cells

scientific article

An accessory cell-derived costimulatory signal acts independently of protein kinase C activation to allow T cell proliferation and prevent the induction of unresponsiveness

scientific article

Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo

scientific article

Antigen presentation by resting B cells. Effectiveness at inducing T cell proliferation is determined by costimulatory signals, not T cell receptor occupancy.

scientific article published on March 1990

Antigen presentation to naive CD4 T cells in the lymph node.

scientific article

Antigen-specific CD4+ T cells that survive after the induction of peripheral tolerance possess an intrinsic lymphokine production defect

scientific article

Autoimmunity: when self-tolerance breaks down.

scientific article published on April 1997

BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors

scientific article published on 03 May 2019

CD154+ graft antigen-specific CD4+ T cells are sufficient for chronic rejection of minor antigen incompatible heart grafts

scientific article published on 01 June 2006

CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells.

scientific article

CD28 promotes CD4+ T cell clonal expansion during infection independently of its YMNM and PYAP motifs.

scientific article

CD4(+) T cell anergy prevents autoimmunity and generates regulatory T cell precursors

scientific article published on February 2016

CD4+ T Cell Persistence and Function after Infection Are Maintained by Low-Level Peptide:MHC Class II Presentation ⬇️

scientific article published on February 4, 2013

CD4+ T Cells: guardians of the phagosome

scientific article published on April 2014

CD4+ T cells that enter the draining lymph nodes after antigen injection participate in the primary response and become central-memory cells

scientific article

CD4+ memory T cell survival.

scientific article published on 27 April 2011

Calnexin induces expansion of antigen-specific CD4(+) T cells that confer immunity to fungal ascomycetes via conserved epitopes.

scientific article

Cell and receptor requirements for streptococcal pyrogenic exotoxin T-cell mitogenicity.

scientific article published on March 1991

Characterization of CD4+ T cell responses during natural infection with Salmonella typhimurium

scientific article

Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection

scientific article published on 12 March 2015

Chrysalis: A New Method for High-Throughput Histo-Cytometry Analysis of Images and Movies

scientific article published on 03 December 2018

Clonal expansion of antigen-specific CD4 T cells following infection with Salmonella typhimurium is similar in susceptible (Itys) and resistant (Ityr) BALB/c mice

scientific article

Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy

scientific article published on January 1989

Co-stimulatory functions of antigen-presenting cells

scientific article published on November 1, 1992

Costimulating factors and signals relevant for antigen presenting cell function

scientific article published on January 1993

Cutting Edge: Adenosine A2a Receptor Signals Inhibit Germinal Center T Follicular Helper Cell Differentiation during the Primary Response to Vaccination

scientific article

Cutting Edge: Allograft Rejection Is Associated with Weak T Cell Responses to Many Different Graft Leukocyte-Derived Peptides

scientific article

Cutting Edge: T Cell-Dependent Plasmablasts Form in the Absence of Single Differentiated CD4+ T Cell Subsets

scientific article published on 14 December 2018

Cutting edge: Bcl6-interacting corepressor contributes to germinal center T follicular helper cell formation and B cell helper function

scientific article published on 11 May 2015

Cutting edge: antigen-dependent regulation of telomerase activity in murine T cells ⬇️

scientific article published on June 15, 1998

Cutting edge: identification of autoreactive CD4+ and CD8+ T cell subsets resistant to PD-1 pathway blockade

scientific article

Cutting edge: type 1 diabetes occurs despite robust anergy among endogenous insulin-specific CD4 T cells in NOD mice

scientific article published on 11 October 2013

Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigen ⬇️

scientific article published on October 15, 2012

Dendritic cell longevity and T cell persistence is controlled by CD154-CD40 interactions

scientific article published on 01 March 2001

Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection ⬇️

scientific article

Development of a novel transgenic mouse for the study of interactions between CD4 and CD8 T cells during graft rejection

scientific article published on 01 November 2003

Different B cell populations mediate early and late memory during an endogenous immune response

scientific article published on 10 February 2011

Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells

scientific article

Diminished antigen processing by endosomal acidification mutant antigen-presenting cells

scientific article published on July 1989

Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity

scientific article published on 01 July 2003

Distinct functions of antigen-specific CD4 T cells during murine Mycobacterium tuberculosis infection

scientific article

Do Memory B Cells Form Secondary Germinal Centers? It Depends

scientific article

Effect of gamma radiation on resting B lymphocytes. II. Functional characterization of the antigen-presentation defect

scientific article published on October 1988

Effects of cyclosporine A on T cell development and clonal deletion

scientific article published on 01 September 1988

Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment

scientific article published on 13 June 2016

Enrichment and Quantification of Epitope-specific CD4+ T Lymphocytes using Ferromagnetic Iron-gold and Nickel Nanowires

scientific article published in Scientific Reports

Focused specificity of intestinal TH17 cells towards commensal bacterial antigens

scientific article

Generation of Th17 cells in response to intranasal infection requires TGF-β1 from dendritic cells and IL-6 from CD301b+ dendritic cells

scientific article

Hapten-specific naïve B cells are biomarkers of vaccine efficacy against drugs of abuse

scientific article published on 23 January 2014

Heterogeneity in the differentiation and function of memory B cells

scientific article published on 21 August 2012

Humoral immunity. Apoptosis and antigen affinity limit effector cell differentiation of a single naïve B cell

scientific article published on 29 January 2015

IL-1 acts on antigen-presenting cells to enhance the in vivo proliferation of antigen-stimulated naive CD4 T cells via a CD28-dependent mechanism that does not involve increased expression of CD28 ligands

scientific article published on April 2004

Identification of MHC-Bound Peptides from Dendritic Cells Infected with Salmonella enterica Strain SL1344: Implications for a Nontyphoidal Salmonella Vaccine.

scientific article

Identification of Natural Regulatory T Cell Epitopes Reveals Convergence on a Dominant Autoantigen

scientific article published in July 2017

Imaging the immune system

scientific article published on 01 February 2008

Immunoregulatory pathways in adult responder mice. I. Induction of GAT-specific tolerance and suppressor T cells for cellular and humoral responses

scientific article published on 01 June 1984

Immunoregulatory pathways in adult responder mice. II. Regulation of delayed-type hypersensitivity responses by GAT-specific suppressor factors present in GAT-tolerant adult responder mice

scientific article published in January 1985

In vivo activation of antigen-specific CD4 T cells.

scientific article

In vivo antigen presentation.

scientific article published on February 2004

In vivo detection of dendritic cell antigen presentation to CD4(+) T cells.

scientific article

In vivo effects of GK1.5 (anti-L3T4a) monoclonal antibody on induction and expression of delayed-type hypersensitivity

scientific article published on 01 May 1985

Increased Effector Memory Insulin-Specific CD4+ T Cells Correlate With Insulin Autoantibodies in Patients With Recent-Onset Type 1 Diabetes.

scientific article published on 25 August 2017

Inflammatory cytokines enhance the in vivo clonal expansion and differentiation of antigen-activated CD4+ T cells ⬇️

scientific article published on July 15, 1997

Inventories of naive and tolerant mouse CD4 T cell repertoires reveal a hierarchy of deleted and diverted T cell receptors

scientific article published on 26 August 2019

Kinetics of CD4+ T cell repopulation of lymphoid tissues after treatment of HIV-1 infection ⬇️

scientific article published on February 3, 1998

Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire.

scientific article published on January 2008

Many Th Cell Subsets Have Fas Ligand-Dependent Cytotoxic Potential.

scientific article published on 7 February 2018

Mechanisms of genetic control of immune responses. II. Nonresponsiveness in BALB/c GT-specific cell-mediated immune responses does not correlate with the absence of functional T cells or the induction of suppressor T cells

scientific article published in January 1986

Molecular mechanisms underlying functional T-cell unresponsiveness.

scientific article published on June 1995

Molecular requirements for T cell activation by the staphylococcal toxic shock syndrome toxin-1.

scientific article published on March 1990

Molecules involved in T-cell costimulation

scientific article

Monocytes provide a novel costimulatory signal to T cells that is not mediated by the CD28/B7 interaction.

scientific article published in January 1994

Most microbe-specific naïve CD4⁺ T cells produce memory cells during infection

scientific article published on January 2016

Naive B Cells with High-Avidity Germline-Encoded Antigen Receptors Produce Persistent IgM+ and Transient IgG+ Memory B Cells

scientific article published on 05 June 2018

Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude.

scientific article

Naive and memory CD4+ T cell survival controlled by clonal abundance

scientific article published on 02 March 2006

Negative selection and peptide chemistry determine the size of naive foreign peptide-MHC class II-specific CD4+ T cell populations

scientific article

Neuroantigen-specific Th2 cells are inefficient suppressors of experimental autoimmune encephalomyelitis induced by effector Th1 cells

scientific article published on 01 November 1995

Normalizing the environment recapitulates adult human immune traits in laboratory mice

scientific article published on 20 April 2016

On the trail of arthritogenic T cells ⬇️

scientific article published on 01 October 2011

Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells.

scientific article published on 20 October 2011

Origins of CD4(+) effector and central memory T cells

scientific article published on June 2011

PD-1, but not PD-L1, expressed by islet-reactive CD4+ T cells suppresses infiltration of the pancreas during type 1 diabetes

scientific article published on 4 April 2013

Peptide:MHCII Tetramer-Based Cell Enrichment for the Study of Epitope-Specific CD4+ T Cells

scientific article published on 29 April 2019

Peripheral immune tolerance blocks clonal expansion but fails to prevent the differentiation of Th1 cells ⬇️

scientific article published on September 1, 1998

Pillars article: antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo. J. Exp. Med. 1987. 165: 302-319.

scientific article published in October 2009

Pillars article: visualization of Peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity. 1994. 1: 327-339.

scientific article published in December 2013

Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire

scholarly article

Preferential accumulation of antigen-specific effector CD4 T cells at an antigen injection site involves CD62E-dependent migration but not local proliferation

scientific article

Prevention of peripheral tolerance by a dendritic cell growth factor: flt3 ligand as an adjuvant

scientific article

Primary induction of CD4 T cell responses in nasal associated lymphoid tissue during group A streptococcal infection.

scientific article published in October 2004

Proliferating CD4+ T cells undergo immediate growth arrest upon cessation of TCR signaling in vivo

scientific article published in January 2008

Prolonged survival without posttransplant immunosuppression in a large animal model

scientific article published on 01 August 1994

Regulatory CD4+ T Cells Recognize MHC-II-Restricted Peptide Epitopes of Apolipoprotein B.

scientific article published on 27 March 2018

Regulatory T Cells: A Crisis Averted

scientific article published on 01 May 2016

Response to comment on “The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude”.

scientific article published in March 2013

Revealing the in vivo behavior of CD4+ T cells specific for an antigen expressed in Escherichia coli ⬇️

scientific article published on April 1, 1998

Robust Antigen Specific Th17 T Cell Response to Group A Streptococcus Is Dependent on IL-6 and Intranasal Route of Infection ⬇️

scientific article published on September 22, 2011

Salmonella Persist in Activated Macrophages in T Cell-Sparse Granulomas but Are Contained by Surrounding CXCR3 Ligand-Positioned Th1 Cells

scientific article published on 11 December 2018

Self-reactive B lymphocytes overexpressing Bcl-xL escape negative selection and are tolerized by clonal anergy and receptor editing.

scientific article

Self-reactive T cells are present in the peripheral lymphoid tissues of cyclosporin A-treated mice

scientific article published on 01 December 1992

Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection.

scientific article published on May 2013

Studying immunological tolerance by physically monitoring antigen-specific T cells in vivo

scientific article published on February 1996

Suppressor T cell circuits in contact sensitivity. III. A monoclonal T cell hybrid-derived suppressor factor specifically suppresses local DTH transfer by a DNP-specific T cell clone.

scientific article

Surface proteins involved in T cell costimulation

scientific article published on June 1994

T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity

scientific article

T-cell clonal anergy.

scientific article

TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2

scientific article published on 11 March 2019

TCR ITAM multiplicity is required for the generation of follicular helper T-cells.

scientific article published on 11 May 2015

TCR signal quantity and quality in CD4(+) T cell differentiation.

scientific article published on 22 October 2014

The CD28 ligand, B7, enhances IL-2 production by providing a costimulatory signal to T cells ⬇️

scientific article published on September 1, 1992

The Neonatal CD4+ T Cell Response to a Single Epitope Varies in Genetically Identical Mice

scientific article

The human T-cell repertoire grows up.

scientific article published on 05 May 2015

The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles

scientific article published on 22 March 2007

The in vivo response of naive CD4+ T cells

scientific article published on 01 October 2014

The majority of CD4+8- thymocytes are functionally immature ⬇️

scientific article published on September 15, 1991

The murine immune response to the male-specific antigen mouse testicular cytochrome c

scientific article published on 01 August 1993

The role of anergy in peripheral T cell unresponsiveness

scientific article published on 01 January 1994

The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude

scientific article

The transcription factor KLF2 restrains CD4⁺ T follicular helper cell differentiation.

scientific article published on February 2015

The transcription factors Thpok and LRF are necessary and partly redundant for T helper cell differentiation

scientific article

The ups and downs of T cell costimulation

scientific article published on September 1994

Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns

scientific article

Tracking antigen-specific CD4+ T cells throughout the course of chronic Leishmania major infection in resistant mice.

scientific article

Tracking epitope-specific T cells.

scientific article published in January 2009

Tracking salmonella-specific CD4 T cells in vivo reveals a local mucosal response to a disseminated infection

scientific article published in March 2002

Use of adoptive transfer of T-cell-antigen-receptor-transgenic T cell for the study of T-cell activation in vivo

scientific article published on April 1997

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo

scientific article published in July 1994

Visualization of specific B and T lymphocyte interactions in the lymph node

scientific article

Visualizing the first 50 hr of the primary immune response to a soluble antigen.

scientific article published in September 2004

Visualizing the generation of memory CD4 T cells in the whole body

scientific article published in March 2001

nef-naf nexus?

scientific article published on 01 March 1992

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