List of works - Francesca Vinchi

Atherogenesis and iron: from epidemiology to cellular level

scientific article

Data demonstrating the anti-oxidant role of hemopexin in the heart.

scientific article

Haptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug development

scientific article

Heme accumulation in endothelial cells impairs angiogenesis by triggering paraptosis.

scientific article published on 11 December 2017

Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450.

scientific article

Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes

scientific article published on 08 April 2014

Hemopexin counteracts systolic dysfunction induced by heme-driven oxidative stress.

scientific article

Hemopexin prevents endothelial damage and liver congestion in a mouse model of heme overload

scientific journal article

Hemopexin therapy improves cardiovascular function by preventing heme-induced endothelial toxicity in mouse models of hemolytic diseases

scientific article published on 27 February 2013

Hemopexin therapy reverts heme-induced proinflammatory phenotypic switching of macrophages in a mouse model of sickle cell disease

scientific article published on 16 December 2015

Inhibition of neutrophil migration by hemopexin leads to increased mortality due to sepsis in mice

scientific article

Iron Induces Anti-tumor Activity in Tumor-Associated Macrophages.

scientific article published on 8 November 2017

Scavenging reactive oxygen species production normalizes ferroportin expression and ameliorates cellular and systemic iron disbalances in hemolytic mouse model.

scientific article

TET2 deficiency leads to stem cell factor-dependent clonal expansion of dysfunctional erythroid progenitors

scientific article published on 25 September 2018

The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation

scientific article

Therapeutic approaches to limit hemolysis-driven endothelial dysfunction: scavenging free heme to preserve vasculature homeostasis

scientific article published on 27 May 2013

List of works by Francesca Vinchi

Atherogenesis and iron: from epidemiology to cellular level

Data demonstrating the anti-oxidant role of hemopexin in the heart.

Haptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug development

Heme accumulation in endothelial cells impairs angiogenesis by triggering paraptosis.

Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450.

Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes

Hemopexin counteracts systolic dysfunction induced by heme-driven oxidative stress.

Hemopexin prevents endothelial damage and liver congestion in a mouse model of heme overload

Hemopexin therapy improves cardiovascular function by preventing heme-induced endothelial toxicity in mouse models of hemolytic diseases

Hemopexin therapy reverts heme-induced proinflammatory phenotypic switching of macrophages in a mouse model of sickle cell disease

Inhibition of neutrophil migration by hemopexin leads to increased mortality due to sepsis in mice

Iron Induces Anti-tumor Activity in Tumor-Associated Macrophages.

Scavenging reactive oxygen species production normalizes ferroportin expression and ameliorates cellular and systemic iron disbalances in hemolytic mouse model.

TET2 deficiency leads to stem cell factor-dependent clonal expansion of dysfunctional erythroid progenitors

The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation

Therapeutic approaches to limit hemolysis-driven endothelial dysfunction: scavenging free heme to preserve vasculature homeostasis