List of works - Helen Wise

A study of prostacyclin mimetics distinguishes neuronal from neutrophil IP receptors

scientific article published on 01 May 1995

Activation of STAT3 by G alpha(s) distinctively requires protein kinase A, JNK, and phosphatidylinositol 3-kinase

scientific article published on 28 September 2006

Activation of neutrophil-like HL-60 cells by prostaglandin E2.

scientific article published on March 1996

Activation of the prostaglandin EP4-receptor subtype is highly coupled to inhibition of N-formyl-methionyl-leucyl-phenylalanine-stimulated rat neutrophil aggregation

scientific article published on 01 January 1998

Agonists can discriminate between cloned human and mouse prostacyclin receptors

scientific article published in May 2004

Anti-inflammatory activity of ghrelin in human carotid artery cells

scientific article

Characterization of chimeric prostacyclin/prostaglandin D(2) receptors

scientific article published on December 1999

Cyclic AMP-Independent Activation of Neutrophil-like HL-60 Cells by Prostaglandin E2

scientific article published on 01 November 1997

Differential and synergistic effect of nerve growth factor and cAMP on the regulation of early response genes during neuronal differentiation

scientific article published on 29 January 2009

Factors affecting prostacyclin receptor agonist efficacy in different cell types

scientific article

Focus on prostacyclin and its novel mimetics

scientific article published on January 1996

Gi-coupled prostanoid receptors are the likely targets for COX-1-generated prostanoids in rat pheochromocytoma (PC12) cells.

scientific article published on 3 June 2009

Glial cells isolated from dorsal root ganglia express prostaglandin E(2) (EP(4)) and prostacyclin (IP) receptors

scientific article published on 28 April 2011

Identification and characterization of surrogate peptide ligand for orphan G protein-coupled receptor mas using phage-displayed peptide library

scientific article

Impact of cell type and epitope tagging on heterologous expression of G protein-coupled receptor: a systematic study on angiotensin type II receptor

scientific article

Investigation of the prostacyclin (IP) receptor antagonist RO1138452 on isolated blood vessel and platelet preparations

scientific article published on 31 July 2006

Isolated dorsal root ganglion neurones inhibit receptor-dependent adenylyl cyclase activity in associated glial cells

scientific article published in February 2013

Lack of interaction between prostaglandin E2 receptor subtypes in regulating adenylyl cyclase activity in cultured rat dorsal root ganglion cells

scientific article published on 20 March 2006

Lipopolysaccharide differentially modulates expression of cytokines and cyclooxygenases in dorsal root ganglion cells via Toll-like receptor-4 dependent pathways.

scientific article published on 7 March 2014

Longitudinal analysis of clinical serology assay performance and neutralising antibody levels in COVID19 convalescents

scientific article published on 06 August 2020

Nerve growth factor-induced differentiation of PC12 cells is accompanied by elevated adenylyl cyclase activity.

scientific article published on 14 April 2010

Over-expression of the truncated ghrelin receptor polypeptide attenuates the constitutive activation of phosphatidylinositol-specific phospholipase C by ghrelin receptors but has no effect on ghrelin-stimulated extracellular signal-regulated kinase 1

scientific article published on 23 November 2006

Primary sensory neurons regulate Toll-like receptor-4-dependent activity of glial cells in dorsal root ganglia.

scientific article

Properties of chimeric prostacyclin/prostaglandin D2 receptors: site-directed mutagenesis reveals the significance of the isoleucine residue at position 323.

scientific article published in February 2003

Prostacyclin receptor induces STAT1 and STAT3 phosphorylations in human erythroleukemia cells: a mechanism requiring PTX-insensitive G proteins, ERK and JNK.

scientific article published on 24 June 2005

Prostacyclin receptor-dependent inhibition of human erythroleukemia cell differentiation is STAT3-dependent

scientific article

Prostacyclin receptor-induced STAT3 phosphorylation in human erythroleukemia cells is mediated via Galpha(s) and Galpha(16) hybrid signaling

scientific article

Prostacyclin receptor-mediated activation of extracellular signal-regulated kinases 1 and 2.

scientific article

Prostanoid signal integration and cross talk.

scientific article

Protein kinase A-dependent coupling of mouse prostacyclin receptors to Gi is cell-type dependent

scientific article published in August 2003

Reciprocal modulation of anti-IgE induced histamine release from human mast cells by A₁ and A(2B) adenosine receptors.

scientific article

Relaxant actions of nonprostanoid prostacyclin mimetics on human pulmonary artery

scientific article published on April 1997

Signal transduction mechanism of the seabream growth hormone secretagogue receptor

scientific article

The constitutive activity of ghrelin receptors is decreased by co-expression with vasoactive prostanoid receptors when over-expressed in human embryonic kidney 293 cells.

scientific article

The constitutive activity of the ghrelin receptor attenuates apoptosis via a protein kinase C-dependent pathway.

scientific article

The inhibitory effects of non-prostanoid prostacyclin mimetics on rat neutrophil function

scientific article published on 01 May 1996

The role of glial cells in influencing neurite extension by dorsal root ganglion cells

scientific article published on 22 December 2009

The roles played by highly truncated splice variants of G protein-coupled receptors

scientific article published on September 2012

The truncated ghrelin receptor polypeptide (GHS-R1b) acts as a dominant-negative mutant of the ghrelin receptor

scientific article published on 28 November 2006

The truncated ghrelin receptor polypeptide (GHS-R1b) is localized in the endoplasmic reticulum where it forms heterodimers with ghrelin receptors (GHS-R1a) to attenuate their cell surface expression.

scientific article published on 31 August 2011

Why is amitriptyline much weaker than desipramine at decreasing β-adrenoceptor numbers?

scientific article published on 01 March 1985

List of works by Helen Wise

A study of prostacyclin mimetics distinguishes neuronal from neutrophil IP receptors

Activation of STAT3 by G alpha(s) distinctively requires protein kinase A, JNK, and phosphatidylinositol 3-kinase

Activation of neutrophil-like HL-60 cells by prostaglandin E2.

Activation of the prostaglandin EP4-receptor subtype is highly coupled to inhibition of N-formyl-methionyl-leucyl-phenylalanine-stimulated rat neutrophil aggregation

Agonists can discriminate between cloned human and mouse prostacyclin receptors

Anti-inflammatory activity of ghrelin in human carotid artery cells

Characterization of chimeric prostacyclin/prostaglandin D(2) receptors

Cyclic AMP-Independent Activation of Neutrophil-like HL-60 Cells by Prostaglandin E2

Differential and synergistic effect of nerve growth factor and cAMP on the regulation of early response genes during neuronal differentiation

Factors affecting prostacyclin receptor agonist efficacy in different cell types

Focus on prostacyclin and its novel mimetics

Gi-coupled prostanoid receptors are the likely targets for COX-1-generated prostanoids in rat pheochromocytoma (PC12) cells.

Glial cells isolated from dorsal root ganglia express prostaglandin E(2) (EP(4)) and prostacyclin (IP) receptors

Identification and characterization of surrogate peptide ligand for orphan G protein-coupled receptor mas using phage-displayed peptide library

Impact of cell type and epitope tagging on heterologous expression of G protein-coupled receptor: a systematic study on angiotensin type II receptor

Investigation of the prostacyclin (IP) receptor antagonist RO1138452 on isolated blood vessel and platelet preparations

Isolated dorsal root ganglion neurones inhibit receptor-dependent adenylyl cyclase activity in associated glial cells

Lack of interaction between prostaglandin E2 receptor subtypes in regulating adenylyl cyclase activity in cultured rat dorsal root ganglion cells

Lipopolysaccharide differentially modulates expression of cytokines and cyclooxygenases in dorsal root ganglion cells via Toll-like receptor-4 dependent pathways.

Longitudinal analysis of clinical serology assay performance and neutralising antibody levels in COVID19 convalescents

Nerve growth factor-induced differentiation of PC12 cells is accompanied by elevated adenylyl cyclase activity.

Over-expression of the truncated ghrelin receptor polypeptide attenuates the constitutive activation of phosphatidylinositol-specific phospholipase C by ghrelin receptors but has no effect on ghrelin-stimulated extracellular signal-regulated kinase 1

Primary sensory neurons regulate Toll-like receptor-4-dependent activity of glial cells in dorsal root ganglia.

Properties of chimeric prostacyclin/prostaglandin D2 receptors: site-directed mutagenesis reveals the significance of the isoleucine residue at position 323.

Prostacyclin receptor induces STAT1 and STAT3 phosphorylations in human erythroleukemia cells: a mechanism requiring PTX-insensitive G proteins, ERK and JNK.

Prostacyclin receptor-dependent inhibition of human erythroleukemia cell differentiation is STAT3-dependent

Prostacyclin receptor-induced STAT3 phosphorylation in human erythroleukemia cells is mediated via Galpha(s) and Galpha(16) hybrid signaling

Prostacyclin receptor-mediated activation of extracellular signal-regulated kinases 1 and 2.

Prostanoid signal integration and cross talk.

Protein kinase A-dependent coupling of mouse prostacyclin receptors to Gi is cell-type dependent

Reciprocal modulation of anti-IgE induced histamine release from human mast cells by A₁ and A(2B) adenosine receptors.

Relaxant actions of nonprostanoid prostacyclin mimetics on human pulmonary artery

Signal transduction mechanism of the seabream growth hormone secretagogue receptor

The constitutive activity of ghrelin receptors is decreased by co-expression with vasoactive prostanoid receptors when over-expressed in human embryonic kidney 293 cells.

The constitutive activity of the ghrelin receptor attenuates apoptosis via a protein kinase C-dependent pathway.

The inhibitory effects of non-prostanoid prostacyclin mimetics on rat neutrophil function

The role of glial cells in influencing neurite extension by dorsal root ganglion cells

The roles played by highly truncated splice variants of G protein-coupled receptors

The truncated ghrelin receptor polypeptide (GHS-R1b) acts as a dominant-negative mutant of the ghrelin receptor

The truncated ghrelin receptor polypeptide (GHS-R1b) is localized in the endoplasmic reticulum where it forms heterodimers with ghrelin receptors (GHS-R1a) to attenuate their cell surface expression.

Why is amitriptyline much weaker than desipramine at decreasing β-adrenoceptor numbers?