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List of works by Chuo Chen

2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling

scientific article

A Highly Selective Vanadium Catalyst for Benzylic C-H Oxidation

scientific article published on January 2012

A biomimetic route for construction of the [4+2] and [3+2] core skeletons of dimeric pyrrole-imidazole alkaloids and asymmetric synthesis of ageliferins

scientific article

A simple method for the electrophilic cyanation of secondary amines

scientific article published on 6 December 2013

A synthetic combinatorial approach to disabling deviant Hedgehog signaling

scientific article

An Approach to the Core Skeleton of Lancifodilactone F

scientific article published on 28 February 2008

An approach for the synthesis of nakamuric acid

scientific article published on June 2015

Asymmetric Synthesis of Axinellamines A and B.

scientific article published on 8 March 2016

Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence ⬇️

scientific article published on October 2014

Asymmetric synthesis of ageliferin

scientific article published on 08 September 2011

Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development

scientific journal article

Catalytic asymmetric [3+2] cycloaddition of azomethine ylides. Development of a versatile stepwise, three-component reaction for diversity-oriented synthesis

scientific article published in August 2003

Chemical Disruption of Wnt-dependent Cell Fate Decision-making Mechanisms in Cancer and Regenerative Medicine

scientific article

Chemical and biological studies of nakiterpiosin and nakiterpiosinone

scientific article

Construction of the 5,6,7-tricyclic skeleton of lancifodilactone F.

scientific article published on June 2015

Convergent Diversity-Oriented Synthesis of Small-Molecule Hybrids

scientific article published on 01 April 2005

Correction to "A Biomimetic Route for Construction of the [4+2] and [3+2] Core Skeletons of Dimeric Pyrrole-Imidazole Alkaloids and Asymmetric Synthesis of Ageliferins".

scientific article published on 19 October 2016

Correction to "Asymmetric Synthesis of Ageliferin".

scientific article published on 19 October 2016

Correction to a biomimetic route for construction of the [4 + 2] and [3 + 2] core skeletons of dimeric pyrrole-imidazole alkaloids and asymmetric synthesis of ageliferins

scientific article published on 11 January 2013

Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING

scientific article

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA

scientific journal article

Development of a triazole class of highly potent Porcn inhibitors

scientific article published on 11 November 2016

Dimeric pyrrole-imidazole alkaloids: synthetic approaches and biosynthetic hypotheses

scientific article published on 15 May 2014

Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells

scientific article

Diverse chemical scaffolds support direct inhibition of the membrane-bound O-acyltransferase porcupine

scientific article

Identification and characterization of β-sitosterol target proteins

scientific article

In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains

scientific article published on 21 April 2012

Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9

scientific article published on 06 December 2018

Ketone-catalyzed photochemical C(sp3)-H chlorination.

scientific article

Label-free detection of small-molecule-protein interactions by using nanowire nanosensors

scientific article

Molecular basis for the specific recognition of the metazoan cyclic GMP-AMP by the innate immune adaptor protein STING.

scientific article published on 6 July 2015

Natural products as inspiration for the development of new synthetic methods

scientific article published on 9 August 2017

Necroptosis-blocking compound NBC1 targets heat shock protein 70 to inhibit MLKL polymerization and necroptosis

scientific article published on 10 March 2020

ORGANIC SYNTHESIS. Response to Comment on "Asymmetric syntheses of sceptrin and massadine and evidence for biosynthetic enantiodivergence".

scientific article published on 9 July 2015

Palladium-Catalyzed C-H Arylation of 1,2,3-Triazoles

scientific article published on 22 September 2016

Palladium-catalyzed direct functionalization of imidazolinone: synthesis of dibromophakellstatin

scientific article published in June 2007

Rapid access to the core skeleton of the [3 + 2]-type dimeric pyrrole-imidazole alkaloids by triplet ketone-mediated C-H functionalization

scientific article published on 15 December 2017

Regiocontrol in MnIII-Mediated Oxidative Heterobicyclizations: Access to the Core Skeletons of Oroidin Dimers

scientific article published on 01 June 2006

Revisiting the Kinnel-Scheuer hypothesis for the biosynthesis of palau'amine

scientific article

Stereocontrolled Formation of a [4.4]Heterospiro Ring System with Unexpected Inversion of Configuration at the Spirocenter

scientific article published on 9 December 2016

Stereoselective fatty acylation is essential for the release of lipidated WNT proteins from the acyltransferase Porcupine (PORCN)

scientific article published on 08 February 2019

Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation

scientific journal article

Structure-activity relationship studies of small-molecule inhibitors of Wnt response

scientific article published on 18 April 2009

Syntheses of Cyclic Guanidine-Containing Natural Products

scientific article

Syntheses of Sceptrins and Nakamuric Acid and Insights into the Biosyntheses of Pyrrole-Imidazole Dimers

scientific article published on August 2015

Synthesis and structure revision of nakiterpiosin

scientific article published in February 2009

Tankyrase is necessary for canonical Wnt signaling during kidney development

scientific article published on July 2010

The Chemistry and Biology of Nakiterpiosin - C-nor-D-Homosteroids

scientific article

The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation

scientific article

The development of highly potent inhibitors for porcupine

scientific article

The past, present, and future of the Yang reaction

scientific article published on 12 August 2016

Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation

scientific article published on 28 October 2019

Vanadium-Catalyzed C(sp(3))-H Fluorination Reactions

scientific article published on July 2014

Vanadium-catalyzed oxidative Strecker reaction: α-C-H cyanation of para-methoxyphenyl (PMP)-protected primary amines

scientific article published on January 2014

Visible light-promoted metal-free C-H activation: diarylketone-catalyzed selective benzylic mono- and difluorination

scientific article published on 12 November 2013

Visible light-promoted metal-free sp(3)-C-H fluorination

scientific article published on October 2014

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