List of works - Daniel Ricklin

'Stealth' corporate innovation: an emerging threat for therapeutic drug development

scientific article published on 01 November 2019

A Structurally Dynamic N-terminal Helix Is a Key Functional Determinant in Staphylococcal Complement Inhibitor (SCIN) Proteins

scientific article

A molecular insight into complement evasion by the staphylococcal complement inhibitor protein family

scientific article

A structural basis for complement inhibition by Staphylococcus aureus

scientific article

A sweet spot to control complement-induced inflammation

scientific article published on 01 September 2012

Allosteric inhibition of complement function by a staphylococcal immune evasion protein

scientific article

Author Correction: 'Stealth' corporate innovation: an emerging threat for therapeutic drug development

scientific article published on 01 November 2019

Autoregulation of thromboinflammation on biomaterial surfaces by a multicomponent therapeutic coating

scientific article

C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay

scientific article

Characterization of Ehp, a secreted complement inhibitory protein from Staphylococcus aureus

scientific article

Clinical promise of next-generation complement therapeutics

scientific article published on 19 July 2019

Comparative Analysis of Novel Complement-Targeted Inhibitors, MiniFH, and the Natural Regulators Factor H and Factor H-like Protein 1 Reveal Functional Determinants of Complement Regulation.

scientific article

Comparative epitope mapping with saturation transfer difference NMR of sialyl Lewis(a) compounds and derivatives bound to a monoclonal antibody.

scientific article

Complement C3dg-mediated erythrophagocytosis: implications for paroxysmal nocturnal hemoglobinuria.

scientific article

Complement component C3 - The "Swiss Army Knife" of innate immunity and host defense ⬇️

scientific article

Complement evasion by human pathogens

scientific article

Complement-targeted therapeutics

scientific article

Compstatin: a complement inhibitor on its way to clinical application

scientific article

Contribution of chondroitin sulfate A to the binding of complement proteins to activated platelets

scientific article

Correction: Protection of nonself surfaces from complement attack by factor h-binding peptides: implications for therapeutic medicine

Crystallization of human complement component C3b in the presence of a staphylococcal complement-inhibitor protein (SCIN).

scientific article published on 24 April 2009

Design, synthesis and evaluation of monovalent ligands for the asialoglycoprotein receptor (ASGP-R)

scientific article published on 29 August 2009

Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family

scientific article

Diversity in the C3b contact residues and tertiary structures of the staphylococcal complement inhibitor (SCIN) protein family

scientific article published in Journal of Biological Chemistry

Dynamic structural changes during complement C3 activation analyzed by hydrogen/deuterium exchange mass spectrometry

scientific article

Electrostatic contributions drive the interaction betweenStaphylococcus aureusprotein Efb-C and its complement target C3d

scientific article

Generation of analogues of the clinical complement inhibitor compstatin with improved potency and pharmacokinetics

scientific article

Impaired ability of complement activation via the alternative pathway C3 convertase caused by a single-point mutation in the beta chain of C3

scientific article

Incomplete inhibition by eculizumab: mechanistic evidence for residual C5 activity during strong complement activation

scientific article

Innate immunity activation on biomaterial surfaces: a mechanistic model and coping strategies

scientific article

Interactions between coagulation and complement--their role in inflammation

scientific article

Intracellular C4BPA Levels Regulate NF-κB-Dependent Apoptosis

scientific article published on 21 September 2020

Local complement-targeted intervention in periodontitis: proof-of-concept using a C5a receptor (CD88) antagonist

scientific article

Manipulating the mediator: modulation of the alternative complement pathway C3 convertase in health, disease and therapy.

scientific article

Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b

scientific article

Native State of Complement Protein C3d Analysed via Hydrogen Exchange and Conformational Sampling

scientific article published on 24 March 2018

Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency

scientific article

Novel mechanisms and functions of complement.

scientific article published in November 2017

Oligohis-tags: mechanisms of binding to Ni2+-NTA surfaces

scientific article published in July 2009

Preformed mediators of defense-Gatekeepers enter the spotlight

scientific article published in November 2016

Progress and Trends in Complement Therapeutics ⬇️

scientific article published on January 1, 2013

Properdin-Mediated C5a Production Enhances Stable Binding of Platelets to Granulocytes in Human Whole Blood

scientific article published on 25 April 2016

Protection of nonself surfaces from complement attack by factor H-binding peptides: implications for therapeutic medicine

scientific article

Real-time label-free detection of complement activation products in human serum by white light reflectance spectroscopy

scientific article published on 03 May 2009

Recent developments in low molecular weight complement inhibitors

scientific article published on 02 October 2009

Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode.

scientific article published on 24 March 2016

Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor

scientific article

Structure of complement fragment C3b-factor H and implications for host protection by complement regulators

scientific article

Structure-kinetic relationship analysis of the therapeutic complement inhibitor compstatin

scientific article

Structures of C3b in complex with factors B and D give insight into complement convertase formation

scientific article

Sweet Turning Bitter: Carbohydrate Sensing of Complement in Host Defence and Disease

scientific article published on 03 November 2020

Synthesis and activity of thioether-containing analogues of the complement inhibitor compstatin

scientific article

Targeted complement inhibition as a promising strategy for preventing inflammatory complications in hemodialysis

scientific article

The XXIV International Complement Workshop (ICW) on October 10-15, 2012. Preface.

scientific article published in November 2012

Tipping the balance: intricate roles of the complement system in disease and therapy

scientific article published in 2021

List of works by Daniel Ricklin

'Stealth' corporate innovation: an emerging threat for therapeutic drug development

A Structurally Dynamic N-terminal Helix Is a Key Functional Determinant in Staphylococcal Complement Inhibitor (SCIN) Proteins

A molecular insight into complement evasion by the staphylococcal complement inhibitor protein family

A structural basis for complement inhibition by Staphylococcus aureus

A sweet spot to control complement-induced inflammation

Allosteric inhibition of complement function by a staphylococcal immune evasion protein

Author Correction: 'Stealth' corporate innovation: an emerging threat for therapeutic drug development

Autoregulation of thromboinflammation on biomaterial surfaces by a multicomponent therapeutic coating

C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay

Characterization of Ehp, a secreted complement inhibitory protein from Staphylococcus aureus

Clinical promise of next-generation complement therapeutics

Comparative Analysis of Novel Complement-Targeted Inhibitors, MiniFH, and the Natural Regulators Factor H and Factor H-like Protein 1 Reveal Functional Determinants of Complement Regulation.

Comparative epitope mapping with saturation transfer difference NMR of sialyl Lewis(a) compounds and derivatives bound to a monoclonal antibody.

Complement C3dg-mediated erythrophagocytosis: implications for paroxysmal nocturnal hemoglobinuria.

Complement component C3 - The "Swiss Army Knife" of innate immunity and host defense ⬇️

Complement evasion by human pathogens

Complement-targeted therapeutics

Compstatin: a complement inhibitor on its way to clinical application

Contribution of chondroitin sulfate A to the binding of complement proteins to activated platelets

Correction: Protection of nonself surfaces from complement attack by factor h-binding peptides: implications for therapeutic medicine

Crystallization of human complement component C3b in the presence of a staphylococcal complement-inhibitor protein (SCIN).

Design, synthesis and evaluation of monovalent ligands for the asialoglycoprotein receptor (ASGP-R)

Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family

Diversity in the C3b contact residues and tertiary structures of the staphylococcal complement inhibitor (SCIN) protein family

Dynamic structural changes during complement C3 activation analyzed by hydrogen/deuterium exchange mass spectrometry

Electrostatic contributions drive the interaction betweenStaphylococcus aureusprotein Efb-C and its complement target C3d

Generation of analogues of the clinical complement inhibitor compstatin with improved potency and pharmacokinetics

Impaired ability of complement activation via the alternative pathway C3 convertase caused by a single-point mutation in the beta chain of C3

Incomplete inhibition by eculizumab: mechanistic evidence for residual C5 activity during strong complement activation

Innate immunity activation on biomaterial surfaces: a mechanistic model and coping strategies

Interactions between coagulation and complement--their role in inflammation

Intracellular C4BPA Levels Regulate NF-κB-Dependent Apoptosis

Local complement-targeted intervention in periodontitis: proof-of-concept using a C5a receptor (CD88) antagonist

Manipulating the mediator: modulation of the alternative complement pathway C3 convertase in health, disease and therapy.

Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b

Native State of Complement Protein C3d Analysed via Hydrogen Exchange and Conformational Sampling

Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency

Novel mechanisms and functions of complement.

Oligohis-tags: mechanisms of binding to Ni2+-NTA surfaces

Preformed mediators of defense-Gatekeepers enter the spotlight

Progress and Trends in Complement Therapeutics ⬇️

Properdin-Mediated C5a Production Enhances Stable Binding of Platelets to Granulocytes in Human Whole Blood

Protection of nonself surfaces from complement attack by factor H-binding peptides: implications for therapeutic medicine

Real-time label-free detection of complement activation products in human serum by white light reflectance spectroscopy

Recent developments in low molecular weight complement inhibitors

Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode.

Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor

Structure of complement fragment C3b-factor H and implications for host protection by complement regulators

Structure-kinetic relationship analysis of the therapeutic complement inhibitor compstatin

Structures of C3b in complex with factors B and D give insight into complement convertase formation

Sweet Turning Bitter: Carbohydrate Sensing of Complement in Host Defence and Disease

Synthesis and activity of thioether-containing analogues of the complement inhibitor compstatin

Targeted complement inhibition as a promising strategy for preventing inflammatory complications in hemodialysis

The XXIV International Complement Workshop (ICW) on October 10-15, 2012. Preface.

Tipping the balance: intricate roles of the complement system in disease and therapy