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List of works by Stefan Feske

A 10-aa-long sequence in SLP-76 upstream of the Gads binding site is essential for T cell development and function.

scholarly article

A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels

scientific article

A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling.

scientific article published in January 2005

A novel mutation in ORAI1 presenting with combined immunodeficiency and residual T-cell function

scientific article

Agonist-selected T cell development requires strong T cell receptor signaling and store-operated calcium entry.

scientific article published on 14 March 2013

Antiviral and regulatory T cell immunity in a patient with stromal interaction molecule 1 deficiency

scientific article published on 21 December 2011

B cell receptor-mediated calcium signaling is impaired in B lymphocytes of type Ia patients with common variable immunodeficiency

scientific article published on 21 May 2010

Biochemical and functional characterization of Orai proteins

scientific article published on 9 February 2007

CD4⁺ and CD8⁺ T cell-dependent antiviral immunity requires STIM1 and STIM2.

scientific article

CRAC channelopathies

scientific article

CRAC channels and disease - From human CRAC channelopathies and animal models to novel drugs

scientific article published on 11 March 2019

Ca(2+) influx in T cells: how many ca(2+) channels?

scientific article published on 24 April 2013

Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells

scientific article published on 24 June 2015

Ca2+ transport and signalling in enamel cells

scientific article

Ca2+/calcineurin signalling in cells of the immune system ⬇️

scientific article published on November 28, 2003

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

scientific article

Calcium Signaling Controls Pathogenic Th17 Cell-Mediated Inflammation by Regulating Mitochondrial Function

scientific article published on 14 February 2019

Calcium signalling in lymphocyte activation and disease

scientific article published on 17 August 2007

Calpain 2 controls turnover of LFA-1 adhesions on migrating T lymphocytes

scientific article

Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca<sup>2+</sup> channel function

scientific article published on 19 April 2022

Conformational dynamics of STIM1 activation

scientific article published in August 2013

Defective nuclear translocation of nuclear factor of activated T cells and extracellular signal-regulated kinase underlies deficient IL-2 gene expression in Wiskott-Aldrich syndrome

scientific article published on 01 December 2005

Dental enamel cells express functional SOCE channels.

scientific article published on 30 October 2015

Differential regulation of Ca2+ influx by ORAI channels mediates enamel mineralization

scientific article published on 23 April 2019

Diseases caused by mutations in ORAI1 and STIM1

scientific article

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

scientific article

Emerging roles of store-operated Ca²⁺ entry through STIM and ORAI proteins in immunity, hemostasis and cancer

scientific article published on 19 March 2013

Essential role of Orai1 store-operated calcium channels in lactation

scientific article published on 20 April 2015

Eye on ion channels in immune cells

scientific article published on 12 March 2019

Functional Interrogation of Primary Human T Cells via CRISPR Genetic Editing

scholarly article by Xin Chen et al published 1 September 2018 in Journal of Immunology

Hair loss and defective T- and B-cell function in mice lacking ORAI1

scientific article

Hemophagocytic lymphohistiocytosis as presenting manifestation of profound combined immunodeficiency due to an ORAI1 mutation

scientific article published on 17 June 2017

Immunodeficiency due to defects in store‐operated calcium entry ⬇️

scientific article published on November 1, 2011

Immunodeficiency due to mutations in ORAI1 and STIM1.

scientific article published on March 2010

Impaired NFAT regulation and its role in a severe combined immunodeficiency

scientific article published on August 2000

InsP₃receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences

scientific journal article

Interference with Ca(2+) release activated Ca(2+) (CRAC) channel function delays T-cell arrest in vivo

scientific article published on 06 September 2013

Ion channelopathies of the immune system

scientific article published on 7 April 2018

Ion channels and transporters in lymphocyte function and immunity ⬇️

scientific article published on June 15, 2012

Ion channels in innate and adaptive immunity

scientific article published on January 2015

Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activation

scientific article published on 27 April 2015

Molecular regulation of CRAC channels and their role in lymphocyte function ⬇️

scientific article published on October 5, 2012

NFAT control of immune function: New Frontiers for an Abiding Trooper.

scientific article published on 2 March 2018

ORAI1 and STIM1 deficiency in human and mice: roles of store-operated Ca2+ entry in the immune system and beyond.

scientific article published on September 2009

ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia

scientific article

ORAI1 mutations abolishing store-operated Ca2+ entry cause anhidrotic ectodermal dysplasia with immunodeficiency

scientific article published on 15 November 2017

ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation

scientific article published on 18 December 2018

Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis

scientific article published in September 2005

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

scientific article

Physiological and pathophysiological functions of SOCE in the immune system ⬇️

scientific article published on January 1, 2012

Polarized but differential localization and recruitment of STIM1, Orai1 and TRPC channels in secretory cells.

scientific article

Preserved effector functions of human ORAI1- and STIM1-deficient neutrophils

scientific article published on 6 December 2015

Protein kinase C-induced phosphorylation of Orai1 regulates the intracellular Ca2+ level via the store-operated Ca2+ channel.

scientific article

Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice

scientific article

Regulation of lymphocyte function by ORAI and STIM proteins in infection and autoimmunity.

scientific article published on 21 May 2012

Relative contributions of stromal interaction molecule 1 and CalDAG-GEFI to calcium-dependent platelet activation and thrombosis.

scientific article

Ribosome-free terminals of rough ER allow formation of STIM1 puncta and segregation of STIM1 from IP(3) receptors.

scientific article published on 17 September 2009

STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia

scientific article published on 01 September 2018

STIM1 and STIM2 protein deficiency in T lymphocytes underlies development of the exocrine gland autoimmune disease, Sjögren's syndrome ⬇️

scientific article published on August 17, 2012

STIM1 and STIM2-mediated Ca(2+) influx regulates antitumour immunity by CD8(+) T cells

scientific article published on 06 August 2013

STIM1 controls T cell-mediated immune regulation and inflammation in chronic infection

scientific article published on 4 May 2015

STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity

scientific article

STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells

scientific article published on 01 July 2020

STIM2 enhances receptor-stimulated Ca²⁺ signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions.

scientific article

STIM2 targets Orai1/STIM1 to the AKAP79 signaling complex and confers coupling of Ca2+ entry with NFAT1 activation

scientific article published on 29 June 2020

Seeing is believing: Visualizing immune cells and calcium signals at different stages of neuroinflammation

scientific article published on 07 August 2020

Severe combined immunodeficiency due to defective binding of the nuclear factor of activated T cells in T lymphocytes of two male siblings

scientific article published on 01 September 1996

Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes.

scientific article published on 18 June 2007

Store-Operated Ca(2+) Entry in Follicular T Cells Controls Humoral Immune Responses and Autoimmunity

scientific article published on 25 May 2016

Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming.

scientific article published on 10 October 2017

Store-operated CRAC channels regulate gene expression and proliferation in neural progenitor cells

scientific article

Store-operated Ca2+ Entry Modulates the Expression of Enamel Genes.

scientific article

Store-operated Ca2+ entry (SOCE) regulates melanoma proliferation and cell migration

scientific article (publication date: 2014)

Store-operated Ca2+ entry in primary murine lung fibroblasts is independent of classical transient receptor potential (TRPC) channels and contributes to cell migration

scientific article published on 22 April 2020

Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function

scientific article published on 10 October 2016

Store-operated Ca2+ entry through ORAI1 is critical for T cell-mediated autoimmunity and allograft rejection

scientific article published on 18 October 2010

T-cell-specific deletion of STIM1 and STIM2 protects mice from EAE by impairing the effector functions of Th1 and Th17 cells

scientific article published on 27 October 2010

The duration of nuclear residence of NFAT determines the pattern of cytokine expression in human SCID T cells

scientific article published on 01 July 2000

The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling

scientific article published on 01 February 2022

Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels

scientific article published on 12 March 2019

Two types of functionally distinct Ca2+ stores in hippocampal neurons

scientific article published on 19 July 2019

Whole-exome sequencing-based discovery of STIM1 deficiency in a child with fatal classic Kaposi sarcoma

scientific article

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