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List of works by Jerry E. Chipuk

Activation of Nrf2 Is Required for Normal and ChREBPα-Augmented Glucose-Stimulated β-Cell Proliferation

scientific article published on 15 May 2018

Activation of the Mitochondrial Fragmentation Protein DRP1 Correlates with BRAF(V600E) Melanoma

scientific article published in June 2015

Aging of Antiviral CD8+ Memory T Cells Fosters Increased Survival, Metabolic Adaptations, and Lymphoid Tissue Homing

scientific article published on 14 December 2018

Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAF(V600E) inhibition and can be targeted to reduce resistance.

scientific article published on 10 March 2014

Apoptosis: Stabbed in the BAX.

scientific article published in October 2008

B cell lymphoma-2 (BCL-2) homology domain 3 (BH3) mimetics demonstrate differential activities dependent upon the functional repertoire of pro- and anti-apoptotic BCL-2 family proteins

scientific article

BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins

scientific article published on May 2013

BAK/BAX activation and cytochrome c release assays using isolated mitochondria ⬇️

scientific article published on 06 April 2013

BCL-2 proteins: melanoma lives on the edge

scientific article published on 11 August 2015

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

scientific article (publication date: 18 February 2005)

BH3 domains other than Bim and Bid can directly activate Bax/Bak

scientific article

Bcl-xL blocks transforming growth factor-beta 1-induced apoptosis by inhibiting cytochrome c release and not by directly antagonizing Apaf-1-dependent caspase activation in prostate epithelial cells

scientific article published on 24 April 2001

Born to be alive: a role for the BCL-2 family in melanoma tumor cell survival, apoptosis, and treatment

scientific article published on October 2011

Cell death through the ages: The ICDS 25th Anniversary Meeting

scientific article published on 08 March 2020

Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization

scientific article

Connected to death: the (unexpurgated) mitochondrial pathway of apoptosis

scientific article published in October 2005

Death upon a kiss: mitochondrial outer membrane composition and organelle communication govern sensitivity to BAK/BAX-dependent apoptosis

scientific article

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

scientific article

Disruption of mitochondrial electron transport chain function potentiates the pro-apoptotic effects of MAPK inhibition

scientific article published on 25 May 2017

Dissecting p53-dependent apoptosis.

scientific article

Do inducers of apoptosis trigger caspase-independent cell death?

scientific article published in March 2005

Dual suppression of inner and outer mitochondrial membrane functions augments apoptotic responses to oncogenic MAPK inhibition

scientific article published on 18 January 2018

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

scientific article

Examining BCL-2 family function with large unilamellar vesicles

scientific article published on 5 October 2012

FBXW7 regulates a mitochondrial transcription program by modulating MITF.

scientific article published on 17 April 2018

From zero to sixty: cell death signaling in the city that never sleeps

scientific article published on 6 July 2015

GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells

scientific article

Genetically defining the mechanism of Puma- and Bim-induced apoptosis

scientific article published on 21 October 2011

Getting away with murder: how does the BCL‐2 family of proteins kill with immunity? ⬇️

scientific article published on March 25, 2013

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

scientific article published on 07 March 2008

How do I kill thee? Let me count the ways: p53 regulates PARP-1 dependent necrosis

scientific article published on 24 October 2013

Identification and characterization of a novel rat ov-serpin family member, trespin

scientific journal article

Immune biomarkers are more accurate in prediction of survival in ulcerated than in non-ulcerated primary melanomas

scientific article

Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2.

scientific article published on 07 January 2014

Late-onset megaconial myopathy in mice lacking group I Paks

scientific article published on 21 February 2019

Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells.

scientific article published on 24 May 2017

MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network

scientific article published on 14 March 2019

MDM2 and Mitochondrial Function: One Complex Intersection

scientific article published on 01 November 2018

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

scholarly article

Mitochondrial Isolation and Real-Time Monitoring of MOMP

Mitochondrial division is requisite to RAS-induced transformation and targeted by oncogenic MAPK pathway inhibitors

scientific article

Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3.

scientific article

Mitochondrial origins of fractional control in regulated cell death

scientific article published on 21 March 2019

Mitochondrial outer membrane proteins assist Bid in Bax-mediated lipidic pore formation

scientific article published on 25 February 2009

Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis.

scientific article published on 4 December 2014

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

scientific article

PB1-F2 proteins from H5N1 and 20 century pandemic influenza viruses cause immunopathology

scientific article

PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis

scientific article

PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

scientific article

Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription

scientific article

Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis

scientific article published on 29 July 2015

Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination

scientific article

Preclinical pharmacological evaluation of a novel multiple kinase inhibitor, ON123300, in brain tumor models

scientific article

RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions

scientific article published on 20 December 2017

Sensitization to the mitochondrial pathway of apoptosis augments melanoma tumor cell responses to conventional chemotherapeutic regimens.

scientific article

Special Issue on Cell Death: Murder, mystery (and a little bit of mayhem) in Manhattan

scientific article

Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis

scientific article

Survival of HER2-Positive Breast Cancer Cells: Receptor Signaling to Apoptotic Control Centers

scientific article published on May 2013

The BCL-2 family reunion

scientific article published on February 2010

The Role of BH3-Only Proteins in Tumor Cell Development, Signaling, and Treatment

scientific article

The androgen receptor represses transforming growth factor-beta signaling through interaction with Smad3.

scientific article

The deadly landscape of pro-apoptotic BCL-2 proteins in the outer mitochondrial membrane

scientific article published on 14 December 2015

The peroxisomes strike BAK: Regulation of peroxisome integrity by the Bcl-2 family

scientific article published on 13 February 2017

Think We Understand the Role of DRP1 in Mitochondrial Biology? Zinc Again!

Why not add some SPARKL to your life (and death)!?

scientific article published on 17 November 2019

p53 and metabolism: Inside the TIGAR.

scientific article

p53's believe it or not: lessons on transcription-independent death

scientific article published on September 1, 2003

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