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List of works by Martin Tolstrup

A Novel Toll-Like Receptor 9 Agonist, MGN1703, Enhances HIV-1 Transcription and NK Cell-Mediated Inhibition of HIV-1-Infected Autologous CD4+ T Cells

scientific article published on 17 February 2016

ART influences HIV persistence in the female reproductive tract and cervicovaginal secretions

scientific article published on 8 February 2016

Activation of latent human immunodeficiency virus by the histone deacetylase inhibitor panobinostat: a pilot study to assess effects on the central nervous system

scientific article

Administration of Panobinostat Is Associated with Increased IL-17A mRNA in the Intestinal Epithelium of HIV-1 Patients

scientific article published on December 2015

Administration of a Toll-like receptor 9 agonist decreases the proviral reservoir in virologically suppressed HIV-infected patients

scientific article

Albumin–Polymer–Drug Conjugates: Long Circulating, High Payload Drug Delivery Vehicles

Anti-HIV-1 ADCC Antibodies following Latency Reversal and Treatment Interruption.

scientific article published on 24 May 2017

Anti-inflammatory effect of a retrovirus-derived immunosuppressive peptide in mouse models

scientific article

Antiviral and immunological effects of tenofovir microbicide in vaginal herpes simplex virus 2 infection.

scientific article published on 25 September 2012

Beyond antiretroviral therapy: early interventions to control HIV-1 infection

scientific article published on May 2017

Broad activation of latent HIV-1 in vivo

scientific article published on 08 September 2016

Cellular immunogenicity of human papillomavirus vaccines Cervarix and Gardasil in adults with HIV infection

scientific article published on 27 November 2017

Characterization of Intact Proviruses in Blood and Lymph Node from HIV-Infected Individuals Undergoing Analytical Treatment Interruption

article

Characterization of the HIV-1 transcription profile after romidepsin administration in ART-suppressed individuals

article

Combined effect of Vacc-4x, recombinant human granulocyte macrophage colony-stimulating factor vaccination, and romidepsin on the HIV-1 reservoir (REDUC): a single-arm, phase 1B/2A trial

scientific article

Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation

scientific article published on 31 January 2013

Comparison of bone and renal effects in HIV-infected adults switching to abacavir or tenofovir based therapy in a randomized trial

scientific article (publication date: 2012)

Comparison of the immunogenicity and reactogenicity of Cervarix and Gardasil human papillomavirus vaccines in HIV-infected adults: a randomized, double-blind clinical trial

scientific article published on 23 November 2013

Comparison of the immunogenicity of Cervarix® and Gardasil® human papillomavirus vaccines for oncogenic non-vaccine serotypes HPV-31, HPV-33, and HPV-45 in HIV-infected adults

scientific article published on 19 February 2014

Construction of a gamma-retrovirus with a novel tropism dependent on human APJ as entry receptor.

scientific article published on 3 October 2011

Construction of a gammaretrovirus with a novel tropism and wild-type replication kinetics capable of using human APJ as entry receptor

scientific article published on 18 July 2012

Correction for Jensen et al., Timing of Toll-Like Receptor 9 Agonist Administration in Pneumococcal Vaccination Impacts Both Humoral and Cellular Immune Responses as Well as Nasopharyngeal Colonization in Mice.

scientific article published in September 2014

Correction: HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days-Implications for HIV Remission

scientific article published on 25 August 2016

Cysteine 138 mutation in HIV-1 Nef from patients with delayed disease progression

article

Differences in antiretroviral regimens do not impact safety or level of latency reversal in persons receiving romidepsin

scientific article published on 01 July 2018

Disulfide reshuffling triggers the release of a thiol-free anti-HIV agent to make up fast-acting, potent macromolecular prodrugs

scientific article published on December 2014

Dynamics of 103K/N and 184M/V HIV-1 drug resistant populations: relative comparison in plasma virus RNA versus CD45RO+T cell proviral DNA.

scientific article

Editorial commentary: Reversing latency in HIV-infected patients

scientific article published on 12 December 2013

Effects of 24 Week Toll-Like Receptor 9 Agonist Treatment in HIV-1+ Individuals

article

Eliminating the latent HIV reservoir by reactivation strategies: advancing to clinical trials

scientific article published on April 2013

Endotoxemia is associated with altered innate and adaptive immune responses in untreated HIV-1 infected individuals

scientific article

Entecavir therapy induces de novo HIV reverse-transcriptase M184V mutation in an antiretroviral therapy-naive patient

scientific article published in May 2008

Estimating Initial Viral Levels during Simian Immunodeficiency Virus/Human Immunodeficiency Virus Reactivation from Latency

scientific article published on 8 November 2017

Evaluation of cardiovascular biomarkers in HIV-infected patients switching to abacavir or tenofovir based therapy

scientific article

Full fusion competence rescue of the enfuvirtide resistant HIV-1 gp41 genotype (43D) by a prevalent polymorphism (137K)

article

Genetic characterization of the HIV-1 reservoir after Vacc-4x and romidepsin therapy in HIV-1-infected individuals

article

HDAC inhibition induces HIV-1 protein and enables immune-based clearance following latency reversal

scientific article published on 17 August 2017

HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days--Implications for HIV Remission

scientific article published on 2 July 2015

HIV anti-latency treatment mediated by macromolecular prodrugs of histone deacetylase inhibitor, panobinostat

article

HIV-1 reverse transcriptase gene 103K/N and 184M/V combinations in tandem: detection and quantification of HIV-1 populations in the CD45RO+ T-cell compartment by a double-ARMS real-time PCR assay

scientific article published in February 2006

HIV-1 transcriptional activity during frequent longitudinal sampling in aviremic patients on antiretroviral therapy

scientific article

HIV/SIV escape from immune surveillance: focus on Nef

scientific article

High level of HIV-1 drug resistance among patients with HIV-1 and HIV-1/2 dual infections in Guinea-Bissau

scientific article

Highly active macromolecular prodrugs inhibit expression of the hepatitis C virus genome in the host cells.

scientific article published on 7 August 2014

Histone deacetylase inhibitor romidepsin inhibits de novo HIV-1 infections.

scientific article published on 20 April 2015

Human Papillomavirus neutralizing and cross-reactive antibodies induced in HIV-positive subjects after vaccination with quadrivalent and bivalent HPV vaccines

scientific article

IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease

scientific article published on 19 August 2019

Immune checkpoints and the HIV-1 reservoir: proceed with caution

scientific article published on July 2016

Impacts of HIV Cure Interventions on Viral Reservoirs in Tissues

scientific article published on 21 August 2019

In-vivo administration of histone deacetylase inhibitors does not impair natural killer cell function in HIV+ individuals

scientific article published on 01 March 2019

Induction of humoral and cellular immune responses against the HIV-1 envelope protein using γ-retroviral virus-like particles

scientific article

Innate DNA sensing is impaired in HIV patients and IFI16 expression correlates with chronic immune activation

scientific article published on July 2014

Innate Immune Activity Correlates with CD4 T Cell-Associated HIV-1 DNA Decline during Latency-Reversing Treatment with Panobinostat

scientific article

Interleukin-37 Expression Is Increased in Chronic HIV-1-Infected Individuals and Is Associated with Inflammation and the Size of the Total Viral Reservoir

scientific article

International AIDS Society global scientific strategy: towards an HIV cure 2016.

scientific article published on 11 July 2016

Levels of regulatory B cells do not predict serological responses to hepatitis B vaccine.

scientific article published on 23 February 2018

Macromolecular (pro)drugs in antiviral research

scholarly article by Anton A. A. Smith et al published 30 June 2014 in Polymer Chemistry

Macromolecular Antiviral Agents against Zika, Ebola, SARS, and Other Pathogenic Viruses

scientific article published on 25 September 2017

Macromolecular Prodrugs of Ribavirin: Structure-Function Correlation as Inhibitors of Influenza Infectivity

scientific article

Macromolecular prodrugs of ribavirin: Polymer backbone defines blood safety, drug release, and efficacy of anti-inflammatory effects

scientific article published on 9 February 2018

Macromolecular prodrugs of ribavirin: towards a treatment for co-infection with HIV and HCV.

scientific article published on 16 September 2014

Modeling of Experimental Data Supports HIV Reactivation from Latency after Treatment Interruption on Average Once Every 5-8 Days

scientific article

Multiple Homozygous Variants in the STING-EncodingTMEM173Gene in HIV Long-Term Nonprogressors

article

New insights on the phenotype of HIV reservoirs

scientific article published on June 2016

Non-covalent hitchhiking on endogenous carriers as a protraction mechanism for antiviral macromolecular prodrugs

scientific article published on 12 December 2018

Nucleic Acids as a Nature-Inspired Scaffold for Macromolecular Prodrugs of Nucleoside Analogues

scientific article published on 28 January 2019

Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial

scientific article published on 15 September 2014

Polyanionic Macromolecular Prodrugs of Ribavirin: Antiviral Agents with a Broad Spectrum of Activity

scientific article published on 20 January 2016

Polymers fight HIV: potent (pro)drugs identified through parallel automated synthesis.

scientific article published on 9 May 2014

Population-based study of diagnostic assays for Borrelia infection: comparison of purified flagella antigen assay (Ideia, Dako Cytomation) and recombinant antigen assay (Liaison, DiaSorin).

scientific article

Reversal of Latency as Part of a Cure for HIV-1.

scientific article published on 11 December 2015

Romidepsin-induced HIV-1 viremia during effective ART contains identical viral sequences with few deleterious mutations

scientific article

Sequential Vacc-4x and romidepsin during combination antiretroviral therapy (cART): Immune responses to Vacc-4x regions on p24 and changes in HIV reservoirs.

scientific article published on 13 September 2017

T cells detect intracellular DNA but fail to induce type I IFN responses: implications for restriction of HIV replication

scientific article published on 3 January 2014

TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS-CoV-2 infection

scientific article published on 01 March 2022

TLR9 agonist MGN1703 enhances B cell differentiation and function in lymph nodes

scientific article published on 09 July 2019

TLR9-adjuvanted pneumococcal conjugate vaccine induces antibody-independent memory responses in HIV-infected adults

scientific article published on August 2012

Tenofovir selectively regulates production of inflammatory cytokines and shifts the IL-12/IL-10 balance in human primary cells

scientific article published on August 2011

The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo

scientific article published on 17 September 2015

The TLR9 agonist MGN1703 triggers a potent type I interferon response in the sigmoid colon.

scientific article published on 2 August 2017

The histone deacetylase inhibitor panobinostat lowers biomarkers of cardiovascular risk and inflammation in HIV patients

scientific article

The impact of B-cell perturbations on pneumococcal conjugate vaccine response in HIV-infected adults

scientific article

The potential role for romidepsin as a component in early HIV-1 curative efforts

scientific article published on 8 March 2016

Timing of Toll-like receptor 9 agonist administration in pneumococcal vaccination impacts both humoral and cellular immune responses as well as nasopharyngeal colonization in mice

scientific article

Transmission of HIV‐1 Drug‐Resistant Variants: Prevalence and Effect on Treatment Outcome

article

Treatment of HIV-Infected Individuals with the Histone Deacetylase Inhibitor Panobinostat Results in Increased Numbers of Regulatory T Cells and Limits Ex Vivo Lipopolysaccharide-Induced Inflammatory Responses

scientific article published in January 2018

Triple Activity of Lamivudine Releasing Sulfonated Polymers against HIV-1.

scientific article

Using animal models to overcome temporal, spatial and combinatorial challenges in HIV persistence research

scientific article

Vaccination against oncogenic human papillomavirus infection in HIV-infected populations: review of current status and future perspectives

scientific article published on December 2014

cAIMP administration in humanized mice induces a chimerization‐level‐dependent STING response

scientific article published on 06 May 2019

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