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List of works by Yoshiro Saito

24(S)-Hydroxycholesterol induces RIPK1-dependent but MLKL-independent cell death in the absence of caspase-8.

scientific article

24(S)-hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis

scientific article published on 25 May 2011

4-Hydroxynonenal induces adaptive response and enhances PC12 cell tolerance primarily through induction of thioredoxin reductase 1 via activation of Nrf2.

scientific article

6-Hydroxydopamine induces secretion of PARK7/DJ-1 via autophagy-based unconventional secretory pathway

scholarly article by Yasuomi Urano published in January 2018

7-Hydroxycholestrol as a possible biomarker of cellular lipid peroxidation: difference between cellular and plasma lipid peroxidation

scientific article published on 28 December 2013

A comparative study on the hydroperoxide and thiol specificity of the glutathione peroxidase family and selenoprotein P.

scientific article published on 15 August 2002

A liver-derived secretory protein, selenoprotein P, causes insulin resistance.

scientific article published on November 2010

Action of 6-amino-3-pyridinols as novel antioxidants against free radicals and oxidative stress in solution, plasma, and cultured cells.

scientific article published on 19 February 2010

Adaptation to hydrogen peroxide enhances PC12 cell tolerance against oxidative damage

scientific article published in August 2005

Adaptive response induced by lipid peroxidation products in cell cultures

scientific article published on 22 December 2005

Adaptive responses induced by 24S-hydroxycholesterol through liver X receptor pathway reduce 7-ketocholesterol-caused neuronal cell death

scientific article published on 4 December 2013

Antioxidant action of sugar-pendant C60 fullerenes

scientific article published on 21 August 2009

Antioxidant capacity of BO-653, 2,3-dihydro-5-hydroxy-4,6-di-tert-butyl-2,2-dipentylbenzofuran, and uric acid as evaluated by ORAC method and inhibition of lipid peroxidation

scientific article published on 19 February 2008

Application of water-soluble radical initiator, 2,2'-azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride, to a study of oxidative stress

scientific article

Assessment of radical scavenging capacity and lipid peroxidation inhibiting capacity of antioxidant

scientific article

Cell death caused by selenium deficiency and protective effect of antioxidants

scientific article published on 29 July 2003

Central nervous system-specific deletion of transcription factor Nrf1 causes progressive motor neuronal dysfunction.

scientific article

Characterization of cellular uptake and distribution of coenzyme Q10 and vitamin E in PC12 cells

scientific article published on 7 July 2008

Characterization of cellular uptake and distribution of vitamin E.

scientific article

Characterization of monochloramine toxicity on PC12 cells and protective effect of tocopherol via antioxidative function.

scientific article published on April 2005

Characterization of novel furan compounds on the basis of their radical scavenging activity and cytoprotective effects against glutamate- and lipopolysaccharide-induced insults

scientific article

Cholesterol is more susceptible to oxidation than linoleates in cultured cells under oxidative stress induced by selenium deficiency and free radicals

scientific article published on 14 August 2007

Cytoprotective effects of vitamin E homologues against glutamate-induced cell death in immature primary cortical neuron cultures: Tocopherols and tocotrienols exert similar effects by antioxidant function.

scientific article published on 22 August 2010

Cytotoxic effect of formaldehyde with free radicals via increment of cellular reactive oxygen species

scientific article

Cytotoxic effects of various stressors on PC12 cells: involvement of oxidative stress and effect of antioxidants

scientific article published on 21 July 2006

DJ-1 has a role in antioxidative stress to prevent cell death

scientific article

DJ-1 has a role in antioxidative stress to prevent cell death.

scientific article

DJ-1-binding compound B enhances Nrf2 activity through the PI3-kinase-Akt pathway by DJ-1-dependent inactivation of PTEN

scientific article published on 28 December 2019

Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle.

scientific article published on 27 February 2017

Development of a Sol Particle Homogeneous Immunoassay for Measuring Full-Length Selenoprotein P in Human Serum.

scientific article published on 26 December 2014

Distribution of oxidized DJ-1 in Parkinson's disease-related sites in the brain and in the peripheral tissues: effects of aging and a neurotoxin

scientific article published in Scientific Reports

Diverse functions of 24(S)-hydroxycholesterol in the brain.

scientific article published on 12 February 2014

Domain structure of bi-functional selenoprotein P.

scientific article published on August 2004

Effect of oxygen concentration on free radical-induced cytotoxicity.

scientific article published on 7 June 2008

Effect of vitamin E on 24(S)-hydroxycholesterol-induced necroptosis-like cell death and apoptosis

scientific article published on 04 March 2016

Effects of a novel gaseous antioxidative system containing a rosemary extract on the oxidation induced by nitrogen dioxide and ultraviolet radiation

scientific article published on April 2004

Eicosapentaenoic acid down-regulates expression of the selenoprotein P gene by inhibiting SREBP-1c protein independently of the AMP-activated protein kinase pathway in H4IIEC3 hepatocytes

scientific article published on 2 May 2017

Elevation of oxidized DJ-1 in the brain and erythrocytes of Parkinson disease model animals.

scientific article published on 11 August 2010

Endocytic vesicles act as vehicles for glucose uptake in response to growth factor stimulation

scientific article published in 2024

Enhanced CD36 expression changes the role of Nrf2 activation from anti-atherogenic to pro-atherogenic in apoE-deficient mice

scientific article published on 24 August 2012

Enhancement of lipid peroxidation and its amelioration by vitamin E in a subject with mutations in the SBP2 gene

scientific article

Gamma-tocopheryl quinone, not alpha-tocopheryl quinone, induces adaptive response through up-regulation of cellular glutathione and cysteine availability via activation of ATF4.

scientific article published in July 2008

Hydrogen Peroxide Causes Cell Death via Increased Transcription of HOXB13 in Human Lung Epithelial A549 Cells

scientific article published on 28 September 2020

Hydroxyoctadecadienoic acid and oxidatively modified peroxiredoxins in the blood of Alzheimer's disease patients and their potential as biomarkers.

scientific article published on 3 August 2007

Hydroxyoctadecadienoic acid as a potential biomarker for oxidative stress in patients with chronic hepatitis C.

scientific article published on 25 September 2009

Immunostaining of oxidized DJ-1 in human and mouse brains

scientific article

Induction of adaptive response and enhancement of PC12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-delta(12,14)-prostaglandin J2 through up-regulation of cellular glutathione via different mechanisms

scientific article published on 24 March 2006

Induction of adaptive response and enhancement of PC12 cell tolerance by lipopolysaccharide primarily through the upregulation of glutathione S-transferase A3 via Nrf2 activation.

scientific article

Induction of apoptosis and necroptosis by 24(S)-hydroxycholesterol is dependent on activity of acyl-CoA:cholesterol acyltransferase 1.

scientific article

Interleukin-27 Enhances the Potential of Reactive Oxygen Species Generation from Monocyte-derived Macrophages and Dendritic cells by Induction of p47phox

scientific article published on 27 February 2017

Inverse correlation between serum levels of selenoprotein P and adiponectin in patients with type 2 diabetes

scientific article

LECT2 functions as a hepatokine that links obesity to skeletal muscle insulin resistance.

scientific article

Levels of lipid peroxidation in human plasma and erythrocytes: comparison between fatty acids and cholesterol

scientific article published on 15 March 2007

Molecular mechanisms of 6-hydroxydopamine-induced cytotoxicity in PC12 cells: involvement of hydrogen peroxide-dependent and -independent action

scientific article published on 14 December 2006

New aspects of 24(S)-hydroxycholesterol in modulating neuronal cell death

scientific article published on 08 July 2015

Novel compound heterozygous mutations in the SBP2 gene: characteristic clinical manifestations and the implications of GH and triiodothyronine in longitudinal bone growth and maturation

scientific article

Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson's disease patients

scientific article published on 29 July 2016

Oxidation of DJ-1 induced by 6-hydroxydopamine decreasing intracellular glutathione

scientific article

Oxidized DJ-1 Inhibits p53 by Sequestering p53 from Promoters in a DNA-Binding Affinity-Dependent Manner ⬇️

scientific article published on November 12, 2012

Oxidized DJ-1 as a possible biomarker of Parkinson's disease

scientific article published on 09 April 2014

Oxidized Lipoprotein as a Major Vessel Cell Proliferator in Oxidized Human Serum.

scientific article

PARK7 modulates autophagic proteolysis through binding to the N-terminally arginylated form of the molecular chaperone HSPA5

scientific article published on 23 July 2018

Phosphorylation of p66shc mediates 6-hydroxydopamine cytotoxicity

scientific article published on 3 November 2010

Pleckstrin homology domain of p210 BCR-ABL interacts with cardiolipin to regulate its mitochondrial translocation and subsequent mitophagy

scientific article published on 5 December 2017

Polymerization of Oxidized DJ-1 via Noncovalent and Covalent Binding: Significance of Disulfide Bond Formation

scientific article published on 03 June 2019

Preparation and application of monoclonal antibodies against oxidized DJ-1. Significant elevation of oxidized DJ-1 in erythrocytes of early-stage Parkinson disease patients

scientific article

Protective effects of 15-deoxy-Delta12,14-prostaglandin J2 against glutamate-induced cell death in primary cortical neuron cultures: induction of adaptive response and enhancement of cell tolerance primarily through up-regulation of cellular glutath

scientific article published on 01 September 2007

Protein adsorption of ultrafine metal oxide and its influence on cytotoxicity toward cultured cells.

scientific article published in March 2009

Proteomic characterization of oxidative dysfunction in human umbilical vein endothelial cells (HUVEC) induced by exposure to oxidized LDL.

scientific article

Proteomic characterization of the striatum and midbrain treated with 6-hydroxydopamine: alteration of 58-kDa glucose-regulated protein and C/EBP homologous protein.

scientific article

Redox-sensitive DJ-1 protein: an insight into physiological roles, secretion, and therapeutic target

scientific article published in 2022

Regulation of GCL activity and cellular glutathione through inhibition of ERK phosphorylation

scientific article published in January 2008

Selenoprotein P as a diabetes-associated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells

scientific article published on 3 July 2014

Selenoprotein P as a significant regulator of pancreatic β cell function

scientific article published on 01 February 2020

Selenoprotein P in human plasma as an extracellular phospholipid hydroperoxide glutathione peroxidase. Isolation and enzymatic characterization of human selenoprotein p

scientific article

Selenoprotein P, as a predictor for evaluating gemcitabine resistance in human pancreatic cancer cells

scientific article published on November 2004

Selenoprotein P-neutralizing antibodies improve insulin secretion and glucose sensitivity in type 2 diabetes mouse models

scientific article

Selenoprotein-P is down-regulated in prostate cancer, which results in lack of protection against oxidative damage

scientific article published on 17 November 2010

Serum selenium and selenoprotein P in patients with silicosis

scientific article published on 04 July 2012

Serum selenoprotein P, but not selenium, predicts future hyperglycemia in a general Japanese population

scientific article published in Scientific Reports

Simple assessment of radical scavenging capacity of beverages

scientific article

Sustainable and practical degradation of intact chicken feathers by cultivating a newly isolated thermophilic Meiothermus ruber H328.

scientific article

The Association Between Concurrence of Infection and the Onset of Severe Eruption or Liver Injury in Patients Using Antipyretic Analgesics: A Matched, Nested Case-Control Study

scientific article published on 10 June 2020

The protective role of DJ-1 in ultraviolet-induced damage of human skin: DJ-1 levels in the stratum corneum as an indicator of antioxidative defense

scientific article published on 26 October 2015

The role of alpha-tocopherol in motor hypofunction with aging in alpha-tocopherol transfer protein knockout mice as assessed by oxidative stress biomarkers

scientific article published on 20 January 2009

Tocopherol suppresses 24(S)-hydroxycholesterol-induced cell death via inhibition of CaMKII phosphorylation

scientific article published on 07 July 2018

Turning point in apoptosis/necrosis induced by hydrogen peroxide

scientific article published on June 2006

α-Tocopheryl phosphate: uptake, hydrolysis, and antioxidant action in cultured cells and mouse.

scientific article published on 26 March 2011

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