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List of works by Andrea Anichini

A melanoma subtype with intrinsic resistance to BRAF inhibition identified by receptor tyrosine kinases gene-driven classification.

scientific article

AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway

scientific article published on October 2012

APAF-1 signaling in human melanoma.

scientific article

An actionable axis linking NFATc2 to EZH2 controls the EMT-like program of melanoma cells

scientific article published on 01 February 2019

An autologous T cell clone overcomes intra-melanoma heterogeneity for susceptibility to cell-mediated lysis by using multiple lytic mechanisms: in vitro and in vivo analysis

scientific article

An expanded peripheral T cell population to a cytotoxic T lymphocyte (CTL)-defined, melanocyte-specific antigen in metastatic melanoma patients impacts on generation of peptide-specific CTLs but does not overcome tumor escape from immune surveillanc

scientific article

Analysis of human class II antigens by cloned cytolytic T cell reagents: a study using HLA loss mutant lymphoblastoid cell lines and monoclonal antibodies detecting the HLA-DP product(s)

scientific article published on 01 May 1985

Antibody-Fc/FcR Interaction on Macrophages as a Mechanism for Hyperprogressive Disease in Non-small Cell Lung Cancer Subsequent to PD-1/PD-L1 Blockade

scientific article published on 11 September 2018

Apoptosis protease activator protein-1 expression is dispensable for response of human melanoma cells to distinct proapoptotic agents

scientific article

Association of antigen-processing machinery and HLA antigen phenotype of melanoma cells with survival in American Joint Committee on Cancer stage III and IV melanoma patients.

scientific article published on June 2006

Autologous cellular immune response to primary and metastatic human melanomas and its regulation by DR antigens expressed on tumor cells

scientific article

BIM upregulation and ROS-dependent necroptosis mediate the antitumor effects of the HDACi Givinostat and Sorafenib in Hodgkin lymphoma cell line xenografts.

scientific article published on 24 February 2014

BRAF alterations are associated with complex mutational profiles in malignant melanoma

scientific article published in August 2004

Beta 1-integrins on melanoma clones regulate the interaction with autologous cytolytic T-cell clones

scientific article published on 01 October 1992

Bevacizumab plus fotemustine as first-line treatment in metastatic melanoma patients: clinical activity and modulation of angiogenesis and lymphangiogenesis factors.

scientific article published on 28 October 2010

Boosting T cell-mediated immunity to tyrosinase by vaccinia virus-transduced, CD34(+)-derived dendritic cell vaccination: a phase I trial in metastatic melanoma

scientific article published on August 2004

Brentuximab Vedotin in CD30-Expressing Germ Cell Tumors After Chemotherapy Failure

scientific article published on 24 March 2016

Cancer immunotherapy with peptide-based vaccines: what have we achieved? Where are we going?

scientific article

Cancer immunotherapy: from the lab to clinical applications-Potential impact on cancer centres' organisation

scientific article

Cell retargeting by bispecific monoclonal antibodies. Evidence of bypass of intratumor susceptibility to cell lysis in human melanoma ⬇️

scientific article published on September 1, 1992

Cellular immune response against autologous human malignant melanoma: are in vitro studies providing a framework for a more effective immunotherapy?

scientific article

Clonal analysis of T lymphocyte response to an isolated class I disparity

scientific article published on 01 November 1983

Clonal analysis of cytotoxic T-lymphocyte response to autologous human metastatic melanoma

scientific article published in May 1985

Clonal analysis of the cytolytic T-cell response to human tumors

scientific article published on 01 January 1987

Clonal expansion of T lymphocytes in human melanoma metastases after treatment with a hapten-modified autologous tumor vaccine

scientific article

Coexpression of NRASQ61R and BRAFV600E in human melanoma cells activates senescence and increases susceptibility to cell-mediated cytotoxicity.

scientific article published on July 2006

Comparative assessment of TCRBV diversity in T lymphocytes present in blood, metastatic lesions, and DTH sites of two melanoma patients vaccinated with an IL-7 gene-modified autologous tumor cell vaccine.

scientific article

Correction to: NFATc2 is an intrinsic regulator of melanoma dedifferentiation

scientific article published on 01 May 2019

Correction to: Results of nimotuzumab and vinorelbine, radiation and re-irradiation for diffuse pontine glioma in childhood.

scientific article

Design, selection and optimization of an anti-TRAIL-R2/anti-CD3 bispecific antibody able to educate T cells to recognize and destroy cancer cells

scientific article published on 06 August 2018

Differential patterns of HOX gene expression are associated with specific integrin and ICAM profiles in clonal populations isolated from a single human melanoma metastasis

scientific article published on 01 May 1996

EGFR/MEK/ERK/CDK5-dependent integrin-independent FAK phosphorylated on serine 732 contributes to microtubule depolymerization and mitosis in tumor cells

scientific article published on 3 October 2013

Early Effector T Lymphocytes Coexpress Multiple Inhibitory Receptors in Primary Non-Small Cell Lung Cancer

scientific article

Enrichment of CD56(dim)KIR + CD57 + highly cytotoxic NK cells in tumour-infiltrated lymph nodes of melanoma patients

scientific article

Enrichment of KIR+CD57+ highly cytotoxic NK cells in sentinel lymph nodes of melanoma patients.

scientific article published on 6 May 2014

Expansion of major histocompatibility complex-restricted antimelanoma cytotoxic T-cell lymphocyte clones with identical T-cell receptor from tumor-infiltrating lymphocytes

scientific article published on October 1, 1992

Frequency of cytotoxic T lymphocyte precursors (CTLp) interacting with autologous tumor via the T-cell receptor: limiting dilution analysis of specific CTLp in peripheral blood and tumor-invaded lymph nodes of melanoma patients

scientific article published on 01 August 1994

Gene transfer by retrovirus-derived shuttle vectors in the generation of murine bispecific monoclonal antibodies.

scientific article published on April 1990

Genetic and molecular analyses of lymphocyte-defined HLA-D region specificities

scientific article published on 01 September 1983

Growth-inhibitory and antiangiogenic activity of the MEK inhibitor PD0325901 in malignant melanoma with or without BRAF mutations

scientific article published on August 2009

Gut Microbiota, Metabolome, and Body Composition Signatures of Response to Therapy in Patients with Advanced Melanoma

scientific article published in 2023

HER-2: a biomarker at the crossroads of breast cancer immunotherapy and molecular medicine.

scientific article

HLA class I downregulation is associated with enhanced NK-cell killing of melanoma cells with acquired drug resistance to BRAF inhibitors.

scientific article published on 13 November 2015

HLA-Dw/LD directed cytotoxic T cell clones

scientific article published on 01 July 1984

Heterogeneity of clones from a human metastatic melanoma detected by autologous cytotoxic T lymphocyte clones.

scientific article published on January 1986

Heterogeneous susceptibility of human melanoma clones to monocyte cytotoxicity: role of ICAM-1 defined by antibody blocking and gene transfer

scientific article published on September 1, 1992

High frequency of T cell clonal expansions in primary human melanoma. Involvement of a dominant clonotype in autologous tumor recognition

scientific article published on 12 March 1999

Human cutaneous melanomas lacking MITF and melanocyte differentiation antigens express a functional Axl receptor kinase.

scientific article

Human melanoma cells with high susceptibility to cell-mediated lysis can be identified on the basis of ICAM-1 phenotype, VLA profile and invasive ability

scientific article published on 01 September 1990

IGKV3 proteins as candidate "off-the-shelf" vaccines for kappa-light chain-restricted B-cell non-Hodgkin lymphomas.

scientific article

IL-15, TIM-3 and NK cells subsets predict responsiveness to anti-CTLA-4 treatment in melanoma patients

scientific article published on 7 December 2016

Identification of a novel gp100/pMel17 peptide presented by HLA-A*6801 and recognized on human melanoma by cytolytic T cell clones

scientific article (publication date: April 2002)

Immune Escape Mechanisms in Non Small Cell Lung Cancer

scientific article published on 02 December 2020

Immune response to autologous human melanoma: implication of class I and II MHC products

scientific article

Immunity to cancer: attack and escape in T lymphocyte-tumor cell interaction

scientific article

Immunization of Patients with Malignant Melanoma with Autologous CD34+ Cell-Derived Dendritic Cells Transduced Ex Vivo with a Recombinant Replication-Deficient Vaccinia Vector Encoding the Human Tyrosinase Gene: A Phase I Trial

article

Immunological and pathobiological roles of fibulin-1 in breast cancer.

scientific article

Immunotherapy of melanoma

scientific article published on 01 December 2003

Immunotherapy of metastatic melanoma using genetically engineered GD2-specific T cells

scientific article published on 8 September 2009

Impaired STAT phosphorylation in T cells from melanoma patients in response to IL-2: association with clinical stage

scientific article published on 09 June 2009

Inhibition of anti-class I cytotoxicity by anti-class II monoclonal antibodies (MoAb). I. Blocking of bulk non-DR and non-DQ-directed cytotoxic T cells by MoAb against DR, DQ, and DP

scientific article published on 01 June 1985

Inhibition of anti-class I cytotoxicity by anti-class II monoclonal antibodies (MoAb). II. Blocking of anti-class I CTL clones by anti-DR MoAb

scientific article published on 01 June 1985

Innovative Therapy, Monoclonal Antibodies and Beyond.

scientific article

Interaction with fibronectin regulates cytokine gene expression in human melanoma cells

scientific article published on 01 March 1996

Large-scale feasibility of gene transduction into human CD34+ cell-derived dendritic cells by adenoviral/polycation complex

scientific article published on 01 October 2000

Melanoma cell lysis by human CTL clones: differential involvement of T3, T8 and HLA antigens

scientific article published on 01 June 1987

Microenvironment and tumor inflammatory features improve prognostic prediction in gastro-entero-pancreatic neuroendocrine neoplasms

scientific article published on 09 July 2019

Microfluidic devices modulate tumor cell line susceptibility to NK cell recognition

scientific article

Molecular subtyping of metastatic melanoma based on cell ganglioside metabolism profiles.

scientific article

Monocyte-derived dendritic cells and monocytes migrate to HIV-Tat RGD and basic peptides

article

Multiple VLA antigens on a subset of melanoma clones.

scientific article published on June 1990

Mutation-independent anaplastic lymphoma kinase overexpression in poor prognosis neuroblastoma patients

scientific article

Mutually exclusive NRASQ61R and BRAFV600E mutations at the single-cell level in the same human melanoma

scientific article published on 6 February 2006

NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo.

scientific article published on 06 April 2009

NFATc2 is a potential therapeutic target in human melanoma.

scientific article

NFATc2 is an intrinsic regulator of melanoma dedifferentiation

scientific article published on 21 September 2015

Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib

scientific article

Of Chemoimmunotherapy Sequences and Delayed Disease-modifying Activity in Advanced Urothelial Carcinoma: Vetus Fit Novum

scientific article published on 28 September 2017

Pembrolizumab as Neoadjuvant Therapy Before Radical Cystectomy in Patients With Muscle-Invasive Urothelial Bladder Carcinoma (PURE-01): An Open-Label, Single-Arm, Phase II Study

scientific article published on 20 October 2018

Peptides with dual binding specificity for HLA-A2 and HLA-E are encoded by alternatively spliced isoforms of the antioxidant enzyme peroxiredoxin 5.

scientific article

Perifosine and sorafenib combination induces mitochondrial cell death and antitumor effects in NOD/SCID mice with Hodgkin lymphoma cell line xenografts

scientific article published on 30 January 2013

Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2.

scientific article published on October 2011

Phase II study of perifosine and sorafenib dual-targeted therapy in patients with relapsed or refractory lymphoproliferative diseases

scientific article

Phase II study of sorafenib in patients with relapsed or refractory lymphoma.

scientific article

Phenotypic profile of clones from early cultures of human metastatic melanomas and its modulation by recombinant interferon gamma

scientific article published on 01 October 1986

Prediction of survival in patients with thin melanoma: results from a multi-institution study.

scientific article

Primary cross-resistance to BRAFV600E-, MEK1/2- and PI3K/mTOR-specific inhibitors in BRAF-mutant melanoma cells counteracted by dual pathway blockade

scientific article

Progress in Understanding Complexity and Determinants of Immune-Related Prognostic Subsets in Primary Melanoma

scientific article published on 01 May 2019

Reactivity of human lymphocyte clones to autologous metastatic melanoma cells

scientific article published on 01 January 1988

Regulation of breast cancer response to chemotherapy by fibulin-1.

scientific article published on May 2007

Results of nimotuzumab and vinorelbine, radiation and re-irradiation for diffuse pontine glioma in childhood.

scientific article published on 3 April 2014

Role of Apollon in human melanoma resistance to antitumor agents that activate the intrinsic or the extrinsic apoptosis pathways

scientific article

Role of Macrophage Targeting in the Antitumor Activity of Trabectedin

scientific article published on 01 February 2013

Sema6A and Mical1 control cell growth and survival of BRAFV600E human melanoma cells.

scientific article published on February 2015

Semaphorin 5A drives melanoma progression: role of Bcl-2, miR-204 and c-Myb

scientific article published on 19 November 2018

Skewed T-cell differentiation in patients with indolent non-Hodgkin lymphoma reversed by ex vivo T-cell culture with gammac cytokines

scientific article published on 08 September 2005

Stereoselective inhibition of 3H-glycine binding to cortical membranes of rat brain by amino acids ⬇️

scientific article published on May 1, 1988

Synergistic anti-tumor activity and inhibition of angiogenesis by cotargeting of oncogenic and death receptor pathways in human melanoma

scientific article

T cell infiltration and prognosis in HCC patients

scientific article published on 15 June 2006

T lymphocytes can mediate lysis of autologous melanoma cells by multiple mechanisms: evidence with a single T cell clone

scientific article published on January 1990

T-cell activation and maturation at tumor site associated with objective response to ipilimumab in metastatic melanoma

article

Targeting heat shock proteins on cancer cells: selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand

scientific article published in August 2006

The alpha 3 beta 1 integrin is involved in melanoma cell migration and invasion.

scientific article

The effect of artificial antigen-presenting cells with preclustered anti-CD28/-CD3/-LFA-1 monoclonal antibodies on the induction of ex vivo expansion of functional human antitumor T cells

scientific article published on 25 August 2008

The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms

scientific article

The non-small cell lung cancer immune landscape: emerging complexity, prognostic relevance and prospective significance in the context of immunotherapy

scientific article published on 7 March 2018

The paradox of T-cell-mediated antitumor immunity in spite of poor clinical outcome in human melanoma.

scientific article published on 3 June 2004

Towards combinatorial targeted therapy in melanoma: from pre-clinical evidence to clinical application (review).

scientific article

Translation of a retained intron in tyrosinase-related protein (TRP) 2 mRNA generates a new cytotoxic T lymphocyte (CTL)-defined and shared human melanoma antigen not expressed in normal cells of the melanocytic lineage

scientific article

Treatment of Advanced Merkel Cell Carcinoma: Current Therapeutic Options and Novel Immunotherapy Approaches.

scientific article published in October 2018

Tumor-reactive CD8+ early effector T cells identified at tumor site in primary and metastatic melanoma.

scientific article published on 21 September 2010

Two autologous melanoma-specific and MHC-restricted human T cell clones with identical intra-tumour reactivity do not share the same TCR V alpha and V beta gene families

scientific article published on November 1991

Vaccination with autologous tumor-loaded dendritic cells induces clinical and immunologic responses in indolent B-cell lymphoma patients with relapsed and measurable disease: a pilot study.

scientific article published on 22 September 2008

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