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List of works by Andreas M. Grabrucker

A role for synaptic zinc in ProSAP/Shank PSD scaffold malformation in autism spectrum disorders

scientific article published on 11 September 2013

Actin-Dependent Alterations of Dendritic Spine Morphology in Shankopathies

scientific article

Activity and circadian rhythm influence synaptic Shank3 protein levels in mice

scientific article

Altered Intestinal Morphology and Microbiota Composition in the Autism Spectrum Disorders Associated SHANK3 Mouse Model. ⬇️

scientific article

Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold

scientific article

Application of Polymeric Nanoparticles for CNS Targeted Zinc Delivery In Vivo.

scientific article published on 21 August 2015

Autism-associated SHANK3 mutations impair maturation of neuromuscular junctions and striated muscles

scientific article published on 01 June 2020

Autism-associated mutations in ProSAP2/Shank3 impair synaptic transmission and neurexin-neuroligin-mediated transsynaptic signaling.

scientific article published on October 2012

Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2

scientific article

Behavioral impairments in animal models for zinc deficiency

scientific article

Brain-Delivery of Zinc-Ions as Potential Treatment for Neurological Diseases: Mini Review.

scientific article published on September 2011

Cellular Zinc Homeostasis Contributes to Neuronal Differentiation in Human Induced Pluripotent Stem Cells

scientific article published on 9 May 2016

Characterization of biometal profiles in neurological disorders.

scientific article published on May 2014

Characterization of lysosome-destabilizing DOPE/PLGA nanoparticles designed for cytoplasmic drug release

scientific article published on 02 June 2014

Characterization of zinc amino acid complexes for zinc delivery in vitro using Caco-2 cells and enterocytes from hiPSC.

scientific article published on 17 July 2017

Concentrations of Essential Trace Metals in the Brain of Animal Species-A Comparative Study

scientific article published on 17 July 2020

Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation

scientific article

De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability.

scientific article published in November 2017

Development of novel Zn2+ loaded nanoparticles designed for cell-type targeted drug release in CNS neurons: in vitro evidences

scientific article

Drug delivery across the blood-brain barrier: recent advances in the use of nanocarriers

scientific article published on 09 January 2020

EXPLOITING THE VERSATILITY OF CHOLESTEROL IN NANOPARTICLES FORMULATION

scientific article published on 12 July 2016

Effects of trace metal profiles characteristic for autism on synapses in cultured neurons

scientific article

Efficient targeting of proteins to post-synaptic densities of excitatory synapses using a novel pSDTarget vector system

scientific article published on 22 May 2009

Emerging Use of Nanotechnology in the Treatment of Neurological Disorders

scientific article published on January 2015

Environmental Factors in Autism ⬇️

scientific article published on January 18, 2013

Extracerebral Dysfunction in Animal Models of Autism Spectrum Disorder.

scientific article

Hybrid nanoparticles as a new technological approach to enhance the delivery of cholesterol into the brain.

scientific article published on 30 March 2018

Insight on the fate of CNS-targeted nanoparticles. Part I: Rab5-dependent cell-specific uptake and distribution

scientific article published on 5 December 2013

Insight on the fate of CNS-targeted nanoparticles. Part II: Intercellular neuronal cell-to-cell transport

scientific article

Loss of COMMD1 and copper overload disrupt zinc homeostasis and influence an autism-associated pathway at glutamatergic synapses

scientific article published on 10 July 2014

Molecular and Cellular Mechanisms of Synaptopathies

scientific article published on 30 April 2017

N-Cadherin-mediated cell adhesion is regulated by extracellular Zn(2+).

scientific article published on February 2015

Nanoparticle transport across the blood brain barrier.

scientific article published on January 2016

Nanoparticles as Blood–Brain Barrier Permeable CNS Targeted Drug Delivery Systems

Novel Curcumin loaded nanoparticles engineered for Blood-Brain Barrier crossing and able to disrupt Abeta aggregates

scientific article published on 08 May 2017

Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies.

scientific article published on 15 August 2011

Prospects of Zinc Supplementation in Autism Spectrum Disorders and Shankopathies Such as Phelan McDermid Syndrome.

scientific article

Rare Feeding Behavior of Great-Tailed Grackles (Quiscalus mexicanus) in the Extreme Habitat of Death Valley ⬇️

Reduced plaque size and inflammation in the APP23 mouse model for Alzheimer's disease after chronic application of polymeric nanoparticles for CNS targeted zinc delivery

scientific article published on 27 December 2017

Rho GTPases in the Amygdala-A Switch for Fears?

scientific article published on 26 August 2020

S100B dysregulation during brain development affects synaptic SHANK protein networks via alteration of zinc homeostasis

scientific article published on 05 November 2021

Small-molecule XIAP inhibitors enhance gamma-irradiation-induced apoptosis in glioblastoma

scientific article published on August 2009

Standardization of research methods employed in assessing the interaction between metallic-based nanoparticles and the blood-brain barrier: Present and future perspectives

scientific article published on 18 January 2019

Synaptogenesis of hippocampal neurons in primary cell culture

scientific article published on 3 November 2009

The Nedd4-binding protein 3 (N4BP3) is crucial for axonal and dendritic branching in developing neurons

scientific article published on 17 September 2013

The PSD protein ProSAP2/Shank3 displays synapto-nuclear shuttling which is deregulated in a schizophrenia-associated mutation

scientific article published on 29 December 2013

The Shank3 Interaction Partner ProSAPiP1 Regulates Postsynaptic SPAR Levels and the Maturation of Dendritic Spines in Hippocampal Neurons

scientific article

Zinc Binding to S100B Affords Regulation of Trace Metal Homeostasis and Excitotoxicity in the Brain.

scientific article published in January 2017

Zinc deficiency and low enterocyte zinc transporter expression in human patients with autism related mutations in SHANK3.

scientific article published on 27 March 2017

Zinc in gut-brain interaction in autism and neurological disorders.

scientific article

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