List of works by Michael L Dustin

"Cell biology meets physiology: functional organization of vertebrate plasma membranes"--the immunological synapse

scientific article published on January 2013

A biophysical model of cell adhesion mediated by immunoadhesin drugs and antibodies

scientific article

A checkpoint cliffhanger at the dawn of placental mammals

scientific article published on 01 April 2020

A coupled diffusion-kinetics model for analysis of contact-area FRAP experiment

scientific article published on 4 April 2008

A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals

scientific article published on 14 September 2020

A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center

scientific article

A dynamic view of the immunological synapse

scientific article

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1

scientific article

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1. J. Immunol. 1986. 137: 1270-1274.

scientific article published in May 2011

A mannose 6-phosphate-containing N-linked glycopeptide derived from lysosomal acid lipase is bound to MHC class II in B lymphoblastoid cell lines

scientific article

A microfluidic platform reveals differential response of regulatory T cells to micropatterned costimulation arrays

scientific article

A model for CD2/CD58-mediated adhesion strengthening

scientific article published in April 2005

A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling.

scientific article published in January 2005

A polarizing situation

A supercode for inflammation

scientific article

A tissue-like platform for studying engineered quiescent human T-cells' interactions with dendritic cells

scientific article published on 25 September 2019

A tissue-like platform for studying engineered quiescent human T-cells’ interactions with dendritic cells

article published in 2019

Actin Dynamics and HIV-1 Entry

scientific article published on 14 April 2016

Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling

scientific article

Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway

scientific article

Actin polymerization-dependent activation of Cas-L promotes immunological synapse stability

scientific article

Adhesion-activating phorbol ester increases the mobility of leukocyte integrin LFA-1 in cultured lymphocytes.

scientific article published on May 1996

Adhesive bond dynamics in contacts between T lymphocytes and glass-supported planar bilayers reconstituted with the immunoglobulin-related adhesion molecule CD58

scientific article published in Journal of Biological Chemistry

Affinity measured by microcluster

scientific article published on 3 May 2010

Agile CD22 nanoclusters run rings around fenced BCR.

scientific article published on 8 January 2016

Agrin is required for survival and function of monocytic cells

scientific article

Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation

Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation

scientific article published on 01 July 2021

Altered TCR signaling from geometrically repatterned immunological synapses

scientific article published in November 2005

An X-ray Vision for Phosphoantigen Recognition

scientific article published on 01 April 2019

Analysis of two-dimensional dissociation constant of laterally mobile cell adhesion molecules

scientific article published on 3 November 2006

Anchoring mechanisms for LFA-3 cell adhesion glycoprotein at membrane surface.

scientific article

Antigen Feast or Famine

scientific article published in Science

Antigen receptor engagement delivers a stop signal to migrating T lymphocytes.

scientific article

Author Correction: A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals

scientific article published on 29 October 2020

Author Correction: Human in vitro-induced regulatory T cells display Dlgh1 dependent and PKC-θ restrained suppressive activity

scientific article published on 19 February 2020

Bifunctional nanoarrays for probing the immune response at the single-molecule level

scientific article published on 08 October 2013

Boltzmann energy-based image analysis demonstrates that extracellular domain size differences explain protein segregation at immune synapses

scientific article

CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia

scientific article published on June 2009

CD28-CD80 interactions control regulatory T cell motility and immunological synapse formation

scientific article

CD45 exclusion– and cross-linking–based receptor signaling together broaden FcεRI reactivity

scientific article published on 18 December 2018

CD8 helps TCR catch slippery self pMHC

scientific article published on 01 December 2018

CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase Ctheta in the immunological synapse

scientific article

CTLs respond with activation and granule secretion when serving as targets for T-cell recognition

scientific article

CX3CR1+ interstitial dendritic cells form a contiguous network throughout the entire kidney.

scientific article

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

scientific article

Capturing resting T cells: the perils of PLL

scientific article published on 23 February 2018

Cell adhesion molecules and actin cytoskeleton at immune synapses and kinapses

scientific article published on 17 October 2007

Cell:cell interactions in the immune system

article published in 2012

Characterization of intercellular adhesion molecule-1 ectodomain (sICAM-1) as an inhibitor of lymphocyte function-associated molecule-1 interaction with ICAM-1

scientific article published on 01 October 1995

Collecting lymphatic vessel permeability facilitates adipose tissue inflammation and distribution of antigen to lymph node-homing adipose tissue dendritic cells

scientific article published on 27 April 2015

Complement Receptors in Myeloid Cell Adhesion and Phagocytosis

scientific article published on November 2016

Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T cells

scientific article published on 30 August 2019

Comprehensive Analysis of Immunological Synapse Phenotypes Using Supported Lipid Bilayers

scientific article

Congenital nephrotic syndrome in mice lacking CD2-associated protein

scientific article published in Science

Control of antigen presentation with a photoreleasable agonist peptide

scientific article published in December 2006

Coordination of T cell activation and migration through formation of the immunological synapse.

scientific article

Correlation of a dynamic model for immunological synapse formation with effector functions: two pathways to synapse formation.

scientific article

Cross talk between CD3 and CD28 is spatially modulated by protein lateral mobility

scientific article published on 30 December 2013

Crosstalk between Regulatory T Cells and Tumor-Associated Dendritic Cells Negates Anti-tumor Immunity in Pancreatic Cancer

scientific article published on July 2017

Cutting Edge: Synapse Propensity of Human Memory CD8 T Cells Confers Competitive Advantage over Naive Counterparts

scientific article published on 14 June 2019

Cutting edge: hierarchy of chemokine receptor and TCR signals regulating T cell migration and proliferation

scientific article published on 01 July 2000

Cutting edge: quantitative imaging of raft accumulation in the immunological synapse

scientific article published in September 2002

Cytoskeletal tension actively sustains the migratory T-cell synaptic contact

scientific article published on 02 January 2020

Cytotoxic T lymphocytes form an antigen-independent ring junction

scientific article

Cytotoxic immunological synapses

scientific article

Decreased blood vessel density and endothelial cell subset dynamics during ageing of the endocrine system

scientific article published on 20 November 2020

Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse

scholarly article by Chiara Beilin et al published 17 October 2018 in Wellcome Open Research

Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse

article published in 2018

Development and migration of plasma cells in the mouse lymph node

scientific article

Distinct behavior of myelomonocytic cells and CD8 T cells underlies the hepatic response to Listeria monocytogenes.

scientific article published on 24 April 2018

Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses

scientific article

Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes

scientific article

Durable Interactions of T Cells with T Cell Receptor Stimuli in the Absence of a Stable Immunological Synapse.

scientific article published in January 2018

Dynamic imaging of the effector immune response to listeria infection in vivo

scientific article

Dynamic imaging of the immune system: progress, pitfalls and promise

scientific article published on July 2006

Dynamics of host defense: the view at the front lines

scientific article published on November 2007

Dynamin-2 Stabilizes the HIV-1 Fusion Pore with a Low Oligomeric State.

scientific article published on January 2017

E-cadherin junction formation involves an active kinetic nucleation process.

scientific article

Effects of insulin receptor down-regulation on hexose transport in human erythrocytes

scientific article published in Journal of Biological Chemistry

Erratum: Costimulation and endogenous MHC ligands contribute to T cell recognition

scholarly article published in Nature Immunology

Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster

scientific article

Exploiting the stress response to radiation to sensitize poorly immunogenic tumors to anti-CTLA-4 treatment

scientific article published on March 2013

F-Actin-Driven CD28-CD80 Localization in the Immune Synapse

Feedback control of regulatory T cell homeostasis by dendritic cells in vivo

scientific article published on 10 August 2009

Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain

scientific article

Force Bistability in Adhesion Switch.

scientific article

Force and affinity in ligand discrimination by the TCR.

scientific article published on 17 November 2014

Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells

scientific article published on January 2007

Foxo4- and Stat3-dependent IL-10 production by progranulin in regulatory T cells restrains inflammatory arthritis

scientific article published on 23 December 2016

Full control of ligand positioning reveals spatial thresholds for T cell receptor triggering

scholarly article by Haogang Cai et al published July 2018 in Nature Nanotechnology

Functional anatomy of T cell activation and synapse formation

scientific article published on January 2010

Functional evidence that intercellular adhesion molecule-1 (icam-1) is a ligand for lfa-1d-ependent adhesion in t cell-mediated cytotoxicity

article

Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse

scientific article

Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter

scientific article

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

scientific article published on 01 October 2019

HIV Envelope gp120 Alters T Cell Receptor Mobilization in the Immunological Synapse of Uninfected CD4 T Cells and Augments T Cell Activation

scientific article

HIV envelope gp120 activates LFA-1 on CD4 T-lymphocytes and increases cell susceptibility to LFA-1-targeting leukotoxin (LtxA)

scientific article (publication date: 2011)

HIV-1 Virological Synapse is not Simply a Copycat of the Immunological Synapse

scientific article published on May 2010

Help to go: T cells transfer CD40L to antigen-presenting B cells.

scientific article published on 22 December 2016

High plasma membrane lipid order imaged at the immunological synapse periphery in live T cells

scientific article published on August 2010

High-Throughput Mechanobiology Screening Platform Using Micro- and Nanotopography

scientific article

How T cells lose their touch

scientific article published on February 2014

Human immunodeficiency virus type 1 envelope gp120 induces a stop signal and virological synapse formation in noninfected CD4+ T cells

scientific article

Human immunodeficiency virus type 1 envelope gp120-induced partial T-cell receptor signaling creates an F-actin-depleted zone in the virological synapse

scientific article

Human in vitro-induced regulatory T cells display Dlgh1dependent and PKC-θ restrained suppressive activity

scientific article published on 26 June 2017

Hunter to gatherer and back: immunological synapses and kinapses as variations on the theme of amoeboid locomotion

scientific article published on January 2008

ICAM-1 a ligand for LFA-1-dependent adhesion of B, T and myeloid cells

scientific article published in January 1988

ICAM-1 co-stimulates target cells to facilitate antigen presentation

scientific article

IMMUNOLOGY: When F-actin Becomes Too Much of a Good Thing

scientific article published in Science

Identification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes

scientific article published on 24 February 2022

Identification of self through two-dimensional chemistry and synapses.

scientific article

Identification of transcriptional regulators in the mouse immune system

scientific article

Imaging of HIV-1 envelope-induced virological synapse and signaling on synthetic lipid bilayers

scientific article

Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation

scientific article

Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells

scientific article published on 18 June 2016

Immuno-phenotypes of Pancreatic Ductal Adenocarcinoma: Metaanalysis of transcriptional subtypes

Immunology: Dendritic Cells Pull the T Cell’s Strings

scholarly article by Sudha Kumari & Michael L Dustin published May 2015 in Current Biology

Immunophenotypes of pancreatic ductal adenocarcinoma: Meta‐analysis of transcriptional subtypes

In silico models for cellular and molecular immunology: successes, promises and challenges.

scientific article published in October 2003

In vivo imaging approaches in animal models of rheumatoid arthritis

scientific article

In vivo imaging of germinal centres reveals a dynamic open structure

scientific article

In vivo multiphoton microscopy technique to reveal the physiology of the mouse placenta

scientific article

In vivo multiphoton microscopy technique to reveal the physiology of the mouse uterus

scientific article

Increased generation of Foxp3(+) regulatory T cells by manipulating antigen presentation in the thymus

scientific article published on 29 February 2016

Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1)

article

Induction by IL 1 and interferon-γ: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J. Immunol. 1986. 137: 245-254.

scientific article published in May 2011

Inflammasome-mediated inhibition of Listeria monocytogenes-stimulated immunity is independent of myelomonocytic function

scientific article

Influence of receptor lateral mobility on adhesion strengthening between membranes containing LFA-3 and CD2 ⬇️

scientific article published on October 1, 1991

Innate response to focal necrotic injury inside the blood-brain barrier.

scientific article

Insights into function of the immunological synapse from studies with supported planar bilayers

scientific article published on January 2010

Integrative analysis of T cell motility from multi-channel microscopy data using TIAM.

scientific article

Integrin inside-out signaling and the immunological synapse

scientific article

Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses

scientific article published on July 2009

Integrins and Their Role in Immune Cell Adhesion

scientific article published on 02 April 2019

Intercellular adhesion molecule-1 dimerization and its consequences for adhesion mediated by lymphocyte function associated-1.

scientific article published on November 1995

Interference with Ca(2+) release activated Ca(2+) (CRAC) channel function delays T-cell arrest in vivo

scientific article published on 06 September 2013

Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids

scientific article

Intravital two-photon microscopy of host-pathogen interactions in a mouse model of Staphylococcus aureus skin abscess formation

scientific article published on 24 December 2012

Killers on sterols

scientific article published in Nature

Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain

scientific article published on October 2009

LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation

scientific article

Lateral Membrane Waves Constitute a Universal Dynamic Pattern of Motile Cells

scientific article published in Physical Review Letters

Liquidity in immune cell signaling

scientific article published in Science

Localizing order to boost signaling

scientific article published on 30 March 2017

Low affinity of cell surface lymphocyte function-associated antigen-1 (LFA-1) generates selectivity for cell-cell interactions

scientific article published on 01 September 1997

Lrp4 is a receptor for Agrin and forms a complex with MuSK

scientific journal article

Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells.

scientific article published on 24 May 2017

Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells

scientific article published on July 1988

Maintenance of CD4 T cell fitness through regulation of Foxo1

scientific article published on 09 July 2018

Making a little affinity go a long way: a topological view of LFA-1 regulation

scientific article published on 01 January 1998

Making the T cell receptor go the distance: a topological view of T cell activation

scientific article published on April 1997

Measuring diffusion and binding kinetics by contact area FRAP.

scientific article published on 4 April 2008

Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells

scientific article

Mechanisms of Cellular Avidity Regulation in CD2–CD58-Mediated T Cell Adhesion

Mechanosensing in T lymphocyte activation

scientific article published on January 2012

Membrane domains and the immunological synapse: keeping T cells resting and ready.

scientific article

Membrane nanoclusters of FcγRI segregate from inhibitory SIRPα upon activation of human macrophages.

scientific article

Membranes as messengers in T cell adhesion signaling

scientific article published on April 2004

Micromanipulation of adhesion of a Jurkat cell to a planar bilayer membrane containing lymphocyte function-associated antigen 3 molecules ⬇️

scientific article published on February 1, 1992

Micromanipulation of adhesion of phorbol 12-myristate-13-acetate-stimulated T lymphocytes to planar membranes containing intercellular adhesion molecule-1 ⬇️

scientific article published on July 1, 1992

Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells.

scientific article

Micropatterning of costimulatory ligands enhances CD4+ T cell function

scientific article

Migration of cytotoxic lymphocytes in cell cycle permits local MHC I-dependent control of division at sites of viral infection

scientific article

Mitochondrial and plasma membrane pools of stomatin-like protein 2 coalesce at the immunological synapse during T cell activation

scientific article

Mitochondrial fusion fuels T cell memory

scientific article published on 12 August 2016

Modular design of immunological synapses and kinapses

scientific article published on July 2009

Modulation of T cell activation by stomatin-like protein 2

scientific article

Molecular Occupancy of Nanodot Arrays

scientific article

Monocyte trafficking to hepatic sites of bacterial infection is chemokine independent and directed by focal intercellular adhesion molecule-1 expression

scientific article

Motility and ultrastructure of large granular lymphocytes on lipid bilayers reconstituted with adhesion receptors LFA-1, ICAM-1, and two isoforms of LFA-3 ⬇️

scientific article published on November 1, 1991

Multifaceted influence of pre-mitotic cytotoxicity of primed CD8 T cells on immunity and infection

Multiscale analysis of T cell activation: correlating in vitro and in vivo analysis of the immunological synapse

scientific article

Myeloid cells limit production of antibody-secreting cells after immunization in the lymph node

scientific article

Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis

scientific article

Nanoengineering of Immune Cell Function

scientific article

Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse

scientific article

Nanoscale ligand spacing influences receptor triggering in T cells and NK cells

scientific article

Natural killers shed attachments to kill again

Neural and immunological synaptic relations

scientific article

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells

scientific article

New insights into the T cell synapse from single molecule techniques

scientific article published on 09 September 2011

Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

scientific article published on 6 November 2005

Opening the frontier of the T cell surface: Schlossman and Goldstein

scientific article

Opposing Effects of PKCθ and WASp on Symmetry Breaking and Relocation of the Immunological Synapse

scholarly article by Tasha N. Sims et al published May 2007 in Cell

PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis

scientific article published on 25 March 2013

PKC-θ function at the immunological synapse: prospects for therapeutic targeting

scientific article published on 04 July 2011

PKC-θ: hitting the bull's eye

article by Michael L Dustin et al published November 2011 in Nature Immunology

Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes

Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria

scientific article

Phagocytes Get Close to Their Enemies

scientific article published on January 2016

Phospholipase D1 regulates lymphocyte adhesion via upregulation of Rap1 at the plasma membrane

scientific article published on 30 March 2009

Pillars article: The immunological synapse: a molecular machine controlling T cell activation. Science. 1999. 285: 221-227.

scientific article published in May 2015

Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse

scientific article published on 02 February 2014

Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families

scientific journal article

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality

scientific article published on 13 June 2016

Protein kinase C theta regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL.

scientific article published on October 2008

Protein kinase C-theta mediates negative feedback on regulatory T cell function

scientific article published on 25 March 2010

Protein tyrosine phosphatase PTPN22 regulates LFA-1 dependent Th1 responses

article

Purified lymphocyte function-associated antigen-3 and T11 target structure are active in CD2-mediated T cell stimulation

article

Quantification and modeling of tripartite CD2-, CD58FC chimera (alefacept)-, and CD16-mediated cell adhesion.

scientific article published on 2 October 2007

Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response

scholarly article

RETRACTED: Steering CAR T Cells into Solid Tumors

retracted scientific article published on 17 January 2019

Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells.

scientific article published on September 2008

Receptor signaling clusters in the immune synapse

scientific article published on 23 February 2012

Reconstitution of immune cell interactions in free-standing membranes

scientific article published in 2018

Reconstitution of immune cell interactions in free-standing membranes

Regulation of T cell migration through formation of immunological synapses: the stop signal hypothesis.

scientific article

Regulation of locomotion and cell-cell contact area by the LFA-1 and ICAM-1 adhesion receptors

scientific article published on May 1992

Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo

scientific article

Renal dendritic cells: an update.

scientific article published on 10 March 2009

Requirements for T lymphocyte migration in explanted lymph nodes.

scientific article

Retraction: Steering CAR T Cells into Solid Tumors. N Engl J Med 2019;380:289-91

scientific article published on 20 February 2019

Role of lymphocyte adhesion receptors in transient interactions and cell locomotion.

scientific article published on January 1991

Role of the crosstalk between CTLA-4 and NKG2D in the development of anti-CTLA-4 treatment strategies

article

Rosetting of activated human T lymphocytes with autologous erythrocytes. Definition of the receptor and ligand molecules as CD2 and lymphocyte function-associated antigen 3 (LFA-3)

scientific article

Rosetting of human T lymphocytes with sheep and human erythrocytes. Comparison of human and sheep ligand binding using purified E receptor

article

Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function

scientific article published on 17 January 2012

Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism

scientific article

Self-reactive human CD4 T cell clones form unusual immunological synapses

scientific article published on 6 February 2012

Signaling and Polarized Communication Across the T Cell Immunological Synapse

scientific article published on 3 August 2016

Signaling at neuro/immune synapses

scientific article

Signaling microdomains in T cells ⬇️

scientific article published on October 19, 2010

Single-cell glycolytic activity regulates membrane tension and HIV-1 fusion

scientific article published on 21 February 2020

Size-dependent protein segregation at membrane interfaces

scientific article published on 07 March 2016

Small GTPases and LFA-1 reciprocally modulate adhesion and signaling

scientific article published on August 2007

Spatial Control of Biological Ligands on Surfaces Applied to T Cell Activation

scientific article published in January 2017

Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation

scientific article

Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo

scientific article

Stimulation of naïve T-cell adhesion and immunological synapse formation by chemokine-dependent and -independent mechanisms

scientific article

Stop and go traffic to tune T cell responses

scientific article published in September 2004

Supergene families meet in the immune system

scientific article published on July 1988

Supported Planar Bilayers for Study of the Immunological Synapse

scholarly article published February 2007

Supported Planar Bilayers for the Formation of Study of Immunological Synapses and Kinapse

scientific article published on 15 September 2008

Supported bilayers at the vanguard of immune cell activation studies

scientific article published on 12 June 2009

Supported planar bilayers in studies on immune cell adhesion and communication.

scientific article

Suppressing T cell motility induced by anti-CTLA-4 monotherapy improves antitumor effects

scientific article

Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells

scientific article

Surface expression of the hRSV nucleoprotein impairs immunological synapse formation with T cells

scientific article

Survival of FimH-expressing enterobacteria in macrophages relies on glycolipid traffic

scientific article published in Nature

Syk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells

scientific article

Synapse propensity of human memory CD8 T cells confers competitive advantage over naïve counterparts

Synaptic asymmetry to go.

scientific article published in March 2008

T Lymphocyte Myosin IIA is Required for Maturation of the Immunological Synapse

scientific article

T cell activation is determined by the number of presented antigens ⬇️

scientific article published on 17 October 2013

T cell antigen receptor activation and actin cytoskeleton remodeling

scientific article published on 14 May 2013

T cell antigen receptor signaling and immunological synapse stability require myosin IIA

scientific article

T cell priming goes through a new phase

scholarly article by David A Blair & Michael L Dustin published April 2013 in Nature Immunology

T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation

scientific article

T cell receptor microcluster transport through molecular mazes reveals mechanism of translocation

scientific article

T cell receptor signaling precedes immunological synapse formation

scientific article

T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster

scientific article

T cell receptors adapt by spacing out.

scientific article published on November 2012

T cell-dendritic cell immunological synapses

scientific article published on 13 June 2006

T cells have a light touch

scientific article published on May 2015

T cells like a firm molecular handshake

scholarly article

T-cell activation through immunological synapses and kinapses

scientific article published on February 2008

T-cell activation: a multidimensional signaling network.

scientific article

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

scientific article

T-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clusters

scientific article

T-cells play the classics with a different spin

scientific article

TCR signaling: the barrier within

scientific article published on February 2014

TCR-mediated adhesion of T cell hybridomas to planar bilayers containing purified MHC class II/peptide complexes and receptor shedding during detachment

scientific article published on 01 September 1996

TFH-derived dopamine accelerates productive synapses in germinal centres.

scientific article published on 12 July 2017

Tapping out a mechanical code for T cell triggering

scientific article published on June 2016

Th1 and Th2 cells form morphologically distinct immunological synapses.

scientific article published on July 2008

The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis

scientific article published on 13 June 2019

The Immune Synapse: Past, Present, and Future

scientific article published on January 2017

The Study of Platelet Receptors Using Artificial Lipid Bilayers

The Zinc Finger Protein Zbtb18 Represses Expression of Class I Phosphatidylinositol 3-Kinase Subunits and Inhibits Plasma Cell Differentiation

scientific article published on 19 February 2021

The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus

scientific article

The cellular context of T cell signaling

scientific article published on April 2009

The class II phosphatidylinositol 3 kinase C2beta is required for the activation of the K+ channel KCa3.1 and CD4 T-cells

scientific article published on 08 July 2009

The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells

scientific article published on 27 April 2009

The critical role of agrin in the hematopoietic stem cell niche.

scientific article

The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice

scientific article

The immunological synapse

scholarly article by Michael L Dustin published November 2014 in Cancer immunology research

The immunological synapse

scholarly article by Michael L Dustin published 9 May 2002 in Arthritis Research

The immunological synapse and CD28-CD80 interactions.

scientific article

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

scientific article published in July 2000

The immunological synapse balances T cell receptor signaling and degradation

scientific article

The immunological synapse.

scientific article

The immunological synapse: integrins take the stage.

scientific article

The induction of intercellular adhesion molecule 1 (ICAM-1) expression on human fetal astrocytes by interferon-gamma, tumor necrosis factor alpha, lymphotoxin, and interleukin-1: relevance to intracerebral antigen presentation

scientific article

The large ectodomains of CD45 and CD148 regulate their segregation from and inhibition of ligated T-cell receptor

scientific article published on 11 April 2013

The lymphocyte function-associated LFA-1, CD2, and LFA-3 molecules: cell adhesion receptors of the immune system

scientific article published on January 1987

The lymphocyte function-associated antigen 1 I domain is a transient binding module for intercellular adhesion molecule (ICAM)-1 and ICAM-3 in hydrodynamic flow

scientific article published on August 1997

The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2

The synapse assembly model.

scientific article

The transcriptional landscape of αβ T cell differentiation

scientific article

The tyrosine phosphatase SHP-1 promotes T cell adhesion by activating the adaptor protein CrkII in the immunological synapse

scientific article published on 08 August 2017

The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease

Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation

scientific article published on 10 February 2013

Tug of war at the exit door

scientific article

Tumor Necrosis Factor Receptor Superfamily in T Cell Priming and Effector Function

Two-dimensional TIRF-SIM-traction force microscopy (2D TIRF-SIM-TFM)

scientific article published on 12 April 2021

Two-photon laser scanning microscopy imaging of intact spinal cord and cerebral cortex reveals requirement for CXCR6 and neuroinflammation in immune cell infiltration of cortical injury sites

scientific article

Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity

scientific article published in 2024

Understanding the structure and function of the immunological synapse

scientific article published on 15 September 2010

Viral spread through protoplasmic kiss

scientific article

Visualization of CD2 interaction with LFA-3 and determination of the two-dimensional dissociation constant for adhesion receptors in a contact area.

scientific article

Visualization of Cell-Cell Interaction Contacts: Synapses and Kinapses

scientific article published on April 2011

Visualization of cell-cell interaction contacts-synapses and kinapses

scientific article published on January 2008

Visualization of mucosal homeostasis via single- and multiphoton intravital fluorescence microscopy

scientific article

Visualizing dendritic cell networks in vivo

scientific article (publication date: December 2004)

Visualizing immune system complexity

scientific article published on 14 April 2009

WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation

scientific article (publication date: February 2002)

What Scales the T Cell Response?

scientific article published on 27 June 2016

What counts in the immunological synapse?

scientific article published on April 2014

What is the importance of the immunological synapse?

scientific article

betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis

scientific article

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