List of works by Brian Hendrich

3D structures of individual mammalian genomes studied by single-cell Hi-C.

scientific article

A high-resolution map of transcriptional repression

scientific article published on 20 March 2017

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

scientific journal article

Breaking the silence in Rett syndrome

scientific article published on 01 October 1999

CHD4 in the DNA-damage response and cell cycle progression: not so NuRDy now

scientific article published on June 2013

Chromatin Remodelling Proteins and Cell Fate Decisions in Mammalian Preimplantation Development

scientific article published in January 2018

Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development

scientific journal article

Combining fluorescence imaging with Hi-C to study 3D genome architecture of the same single cell

scientific article published on 19 April 2018

Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification

scientific article published on 26 June 2015

Cutting Edge: A Critical Role for Gene Silencing in Preventing Excessive Type 1 Immunity

article

Deficiency of Mbd2 suppresses intestinal tumorigenesis

Dynamic reprogramming of DNA methylation in the early mouse embryo.

scientific article

Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice.

scientific article

Epigenetic and Chromosomal Control of Gene Expression: Molecular and Genetic Analysis of X Chromosome Inactivation

article

Epigenetic reprogramming: how now, cloned cow?

scientific article

FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells.

scientific article

Gene silencing quantitatively controls the function of a developmental trans-activator

scientific article published on July 2002

Genomic structure and chromosomal mapping of the murine and human Mbd1, Mbd2, Mbd3, and Mbd4 genes

scientific article

Human diseases with underlying defects in chromatin structure and modification.

scientific article

Identification and characterization of a family of mammalian methyl-CpG binding proteins

scientific article

Identification and characterization of the human XIST gene promoter: implications for models of X chromosome inactivation

scientific article

Kaiso-deficient mice show resistance to intestinal cancer

scientific article

Keeping things quiet: roles of NuRD and Sin3 co-repressor complexes during mammalian development

scientific article published on 14 August 2008

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

scientific article (publication date: September 1999)

MBD3/NuRD facilitates induction of pluripotency in a context-dependent manner

scientific article published on 15 May 2014

Mbd2 contributes to DNA methylation-directed repression of the Xist gene

scientific article published on 12 March 2007

Mbd3 and deterministic reprogramming

Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells

scientific journal article

Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program.

scientific article published on 12 September 2017

MeCP2 dependent heterochromatin reorganization during neural differentiation of a novel Mecp2-deficient embryonic stem cell reporter line

scientific article

MeCP2 in neurons: closing in on the causes of Rett syndrome

scientific article (publication date: 15 April 2005)

Methyl-CpG binding proteins and cancer: are MeCpGs more important than MBDs?

scientific article

NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment

scientific article

NuRD-dependent DNA methylation prevents ES cells from accessing a trophectoderm fate

scientific article published on 7 February 2012

NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression

scientific article

PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex

scientific article published in Nature Communications

Sall4 controls differentiation of pluripotent cells independently of the Nucleosome Remodelling and Deacetylation (NuRD) complex

scientific article

Sin3a is essential for the genome integrity and viability of pluripotent cells

scientific article published on 20 December 2011

Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency.

scientific article published in December 1999

Subunit redundancy within the NuRD complex ensures fidelity of ES cell lineage commitment

The NuRD component Mbd3 is required for pluripotency of embryonic stem cells

scientific journal article

The Nucleosome Remodeling and Deacetylase Complex NuRD Is Built from Preformed Catalytically Active Sub-modules

scientific article

The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression.

scientific article published in July 2018

The Nucleosome Remodelling and Deacetylation complex restricts Mediator access to enhancers to control transcription

The Nucleosome Remodelling and Deacetylation complex suppresses transcriptional noise during lineage commitment

scientific article published on 29 April 2019

The function of chromatin modifiers in lineage commitment and cell fate specification

scientific article

The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus

scientific article (publication date: 30 October 1992)

The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex

scientific article published on 2 May 2015

The methyl-CpG binding domain and the evolving role of DNA methylation in animals

scientific article

The methyl-CpG binding proteins Mecp2, Mbd2 and Kaiso are dispensable for mouse embryogenesis, but play a redundant function in neural differentiation

scientific article

The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis

scientific article published on 20 November 2011

The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor

scientific article

The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

scientific article (publication date: 16 September 1999)

Transcriptional control by Sall4 in blastocysts facilitates lineage commitment of inner cell mass cells

Transcriptional repressors: multifaceted regulators of gene expression

scientific article published on February 2013

Vestiges of a DNA methylation system in Drosophila melanogaster?

scientific article published in December 1999

c-Jun N-terminal phosphorylation antagonises recruitment of the Mbd3/NuRD repressor complex

scientific article published on 2 January 2011

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