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List of works by Matthias Briel

A guidance was developed to identify participants with missing outcome data in randomized controlled trials

scientific article published on 9 July 2019

A methodological survey of the analysis, reporting and interpretation of Absolute Risk ReductiOn in systematic revieWs (ARROW): a study protocol

scientific article published on 13 December 2013

A protocol for a systematic review on the impact of unpublished studies and studies published in the gray literature in meta-analyses

scientific article

A scoping review shows that several nonvalidated budget planning tools for randomized trials are available

scientific article published on 15 September 2019

A systematic review of discontinued trials suggested that most reasons for recruitment failure were preventable

scientific article

A systematic review of nonabsorbable, absorbable, and steroid-impregnated spacers following endoscopic sinus surgery

scientific article published on 24 July 2013

A systematic survey identified 36 criteria for assessing effect modification claims in randomized trials or meta-analyses

scientific article published on 24 May 2019

A users' guide to understanding therapeutic substitutions

scientific article published on 2 December 2013

Academic response to improving value and reducing waste: A comprehensive framework for INcreasing QUality In patient-oriented academic clinical REsearch (INQUIRE).

scientific article published on 7 June 2018

Addressing dichotomous data for participants excluded from trial analysis: a guide for systematic reviewers

scientific article

Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial

scientific article published on 19 January 2015

Adjunct prednisone therapy for patients with community-acquired pneumonia: a randomized, placebo-controlled multicenter trial.

scientific article published on 16 March 2015

Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection

scientific article

Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection: a meta-analysis of randomised controlled trials

scientific article

Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV-infection

scientific article

Adverse events associated with individual statin treatments for cardiovascular disease: an indirect comparison meta-analysis.

scientific article published on 14 September 2011

Agreements between Industry and Academia on Publication Rights: A Retrospective Study of Protocols and Publications of Randomized Clinical Trials.

scientific article published on 28 June 2016

An analysis of protocols and publications suggested that most discontinuations of clinical trials were not based on preplanned interim analyses or stopping rules

scientific article published on 04 June 2015

Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis

scientific article published on 16 February 2009

Association between shortened leukocyte telomere length and cardiometabolic outcomes: systematic review and meta-analysis

scientific article

Association of Supporting Trial Evidence and Reimbursement for Off-Label Use of Cancer Drugs

article by Amanda Katherina Herbrand et al published 1 March 2021 in JAMA Network Open

Author reply: the master-question: meta-analyses and stopped-early randomized trials—a problem?

Authors seldom report the most patient-important outcomes and absolute effect measures in systematic review abstracts

scientific article

Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials

scientific article

Bias in dissemination of clinical research findings: structured OPEN framework of what, who and why, based on literature review and expert consensus

scientific article

Blockade of the renin-angiotensin-aldosterone system (RAAS) for primary prevention of non-valvular atrial fibrillation: a systematic review and meta analysis of randomized controlled trials

scientific article published on 14 March 2012

Blood pressure targets for vasopressor therapy: a systematic review

scientific article published on June 2015

COVID-19 randomised trial protocols: rapid publication without barriers

scientific article published on 15 April 2020

Cardiovascular effects and safety of long-term colchicine treatment: Cochrane review and meta-analysis

scientific article published on February 2016

Cerebrovascular reactivity predicts stroke in high-grade carotid artery disease.

scientific article

Characteristics and interpretation of subgroup analyses based on tumour characteristics in randomised trials testing target-specific anticancer drugs: design of a systematic survey

scientific article published on 30 May 2020

Choice of data extraction tools for systematic reviews depends on resources and review complexity

scientific article

Cl- transport by cystic fibrosis transmembrane conductance regulator (CFTR) contributes to the inhibition of epithelial Na+ channels (ENaCs) in Xenopus oocytes co-expressing CFTR and ENaC.

scientific article published in May 1998

Clinical outcomes associated with procalcitonin algorithms to guide antibiotic therapy in respiratory tract infections

scientific article published in February 2013

Cochrane corner: early statin therapy in acute coronary syndromes—what is the clinical benefit?

Cohort Study of Somatostatin-Based Radiopeptide Therapy With [90Y-DOTA]-TOC Versus [90Y-DOTA]-TOC Plus [177Lu-DOTA]-TOC in Neuroendocrine Cancers

scientific article published on 05 March 2012

Colchicine and Prevention of Cardiovascular Events

scientific article published on September 2016

Colchicine for prevention of cardiovascular events

scientific article (publication date: 27 January 2016)

Colchicine for prevention of cardiovascular events

scientific article

Communication training and antibiotic use in acute respiratory tract infections. A cluster randomised controlled trial in general practice

scientific article published on 01 April 2006

Comparative effectiveness of tenofovir in HIV-infected treatment-experienced patients: systematic review and meta-analysis

scientific article published on 13 December 2016

Comparative effectiveness of tenofovir in treatment-naïve HIV-infected patients: systematic review and meta-analysis.

scientific article

Comparison of randomized controlled trials discontinued or revised for poor recruitment and completed trials with the same research question: a matched qualitative study

scientific article published on 30 December 2019

Completion and Publication Rates of Randomized Controlled Trials in Surgery: An Empirical Study

scientific article published on July 2015

Contrasting evidence to reimbursement reality for off-label use (OLU) of drug treatments in cancer care: rationale and design of the CEIT-OLU project

scientific article published on 01 December 2019

Copeptin predicts 10-year all-cause mortality in community patients: a 10-year prospective cohort study

scientific article

Correction: A methodological survey of the analysis, reporting and interpretation of Absolute Risk ReductiOn in systematic revieWs (ARROW): a study protocol.

scientific article published on 17 July 2014

Corticosteroid Therapy for Patients Hospitalized With Community-Acquired Pneumonia

scientific article

Corticosteroid therapy for acute lung injury, acute respiratory distress syndrome, and severe pneumonia: a meta-analysis of randomized controlled trials

scientific article

Corticosteroid therapy for pneumonia – Author's reply

scientific article published in The Lancet

Corticosteroid therapy for sepsis: a clinical practice guideline

scientific article published in the British Medical Journal

Corticosteroid treatment for community-acquired pneumonia--the STEP trial: study protocol for a randomized controlled trial

scientific article

Corticosteroids in Patients Hospitalized With Community-Acquired Pneumonia: Systematic Review and Individual Patient Data Metaanalysis.

scientific article

Cost-effectiveness of drug-eluting stents in a US Medicare setting:a cost-utility analysis with 3-year clinical follow-up data

scientific article

Cosyntropin testing does not predict response to glucocorticoids in community-acquired pneumonia in a randomized controlled trial

scientific article published on 09 January 2019

Credibility of claims of subgroup effects in randomised controlled trials: systematic review

scientific article

Current use and costs of electronic health records for clinical trial research: a descriptive study

article

Defining publication bias: protocol for a systematic review of highly cited articles and proposal for a new framework

scientific article published on 21 May 2013

Detecting, quantifying and adjusting for publication bias in meta-analyses: protocol of a systematic review on methods

scientific article

Development of the Instrument to assess the Credibility of Effect Modification Analyses (ICEMAN) in randomized controlled trials and meta-analyses

scientific article published on 1 August 2020

Digital tools for trial recruitment and retention-plenty of tools but rigorous evaluation is in short supply

scientific article published on 05 June 2020

Discontinuation and non-publication of randomised clinical trials supported by the main public funding body in Switzerland: a retrospective cohort study.

scientific article

Dissemination bias in systematic reviews of animal research: a systematic review

scientific article

Driving pressure and survival in the acute respiratory distress syndrome.

scientific article published on February 2015

Early nutritional therapy for malnourished or nutritionally at-risk adult medical inpatients

scientific article

Early nutritional therapy for malnourished or nutritionally at‐risk adult medical inpatients

Early stopping of randomized clinical trials for overt efficacy is problematic

scientific article published on March 2008

Economic Evaluation of Reamed versus Unreamed Intramedullary Nailing in Patients with Closed and Open Tibial Fractures: Results from the Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients with Tibial Fractures (SPRINT) ⬇️

scientific article published on May 25, 2011

Economic evaluation of procalcitonin-guided antibiotic therapy in acute respiratory infections: a US health system perspective

scientific article

Effect of different antilipidemic agents and diets on mortality: a systematic review

scientific article

Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis.

scientific article published on 13 October 2017

Effects of antithyroid drugs on radioiodine treatment: systematic review and meta-analysis of randomised controlled trials

scientific article published on 19 February 2007

Effects of early treatment with statins on short-term clinical outcomes in acute coronary syndromes: a meta-analysis of randomized controlled trials

scientific article published in May 2006

Effects of low-carbohydrate vs low-fat diets on weight loss and cardiovascular risk factors: a meta-analysis of randomized controlled trials

scientific article

Effects of procalcitonin testing on antibiotic use and clinical outcomes in patients with upper respiratory tract infections. An individual patient data meta-analysis

scientific article

Effects of statins on stroke prevention in patients with and without coronary heart disease: a meta-analysis of randomized controlled trials

scientific article published in October 2004

Efficacy and safety of statin treatment for cardiovascular disease: a network meta-analysis of 170,255 patients from 76 randomized trials

scientific article

Erratum to "A systematic survey identified 36 criteria for assessing effect modification claims in randomized trials or meta-analyses" [J Clin Epidemiol. 2019;113:159-67]

scientific article published on 3 May 2020

Evaluating prophylactic heparin in ambulatory patients with solid tumours: a systematic review and individual participant data meta-analysis

scientific article published on 01 October 2020

Fibrates for primary prevention of cardiovascular disease events

scientific article

Fibrates for primary prevention of cardiovascular disease events.

scientific article

First-line treatment and outcome of elderly patients with primary central nervous system lymphoma (PCNSL)--a systematic review and individual patient data meta-analysis

scientific article

Four numbers and a bit more basic knowledge of mathematics

scientific article published in February 2015

Funding characteristics of randomised clinical trials supported by the Swiss National Science Foundation: a retrospective cohort study

scientific article published on 29 January 2018

GRADE Equity Guidelines 2: Considering health equity in GRADE guideline development: Equity extension of the Guideline Development Checklist

scientific article published on 9 May 2017

GRADE equity guidelines 1: considering health equity in GRADE guideline development: introduction and rationale

scientific article published on 12 April 2017

GRADE equity guidelines 4: guidance on how to assess and address health equity within the evidence to decision process.

scientific article published on 9 August 2017

GRADE guidelines 17: assessing the risk of bias associated with missing participant outcome data in a body of evidence

scientific article

Generating evidence on a risk-based monitoring approach in the academic setting - lessons learned

scientific article

Guideline of guidelines: thromboprophylaxis for urological surgery

scientific article

Hemodynamic performance of stentless versus stented valves: a systematic review and meta-analysis.

scientific article published on September 2008

Higher versus lower positive end-expiratory pressure in acute lung injury and acute respiratory distress syndrome: systematic review and individual patient data meta-analysis

scientific article published in March 2010

Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis

scientific article published on March 2010

How to write a surgical clinical research protocol: literature review and practical guide

scientific article published on 26 October 2013

Impact of a short version of the CONSORT checklist for peer reviewers to improve the reporting of randomised controlled trials published in biomedical journals: study protocol for a randomised controlled trial

scientific article published on 19 March 2020

Impact of missing participant data for dichotomous outcomes on pooled effect estimates in systematic reviews: a protocol for a methodological study

scientific article

In Reply

Inconsistent definitions for intention-to-treat in relation to missing outcome data: systematic review of the methods literature

scientific article

Infection biomarkers in primary care patients with acute respiratory tract infections-comparison of Procalcitonin and C-reactive protein

scientific article

Influence of hospital characteristics on quality of care in patients with community-acquired pneumonia.

scientific article published on 29 September 2016

Initiation and continuation of randomized trials after the publication of a trial stopped early for benefit asking the same study question: STOPIT-3 study design

scientific article

Instructions for aggregated evidence: About reviews, systematic reviews and meta-analyses (part 2)

scientific article published in October 2015

Insufficient recruitment and premature discontinuation of clinical trials in Switzerland: qualitative study with trialists and other stakeholders

scientific article published on 29 November 2017

Intensive statin therapy compared with moderate dosing for prevention of cardiovascular events: a meta-analysis of >40 000 patients

scientific article published on 08 March 2011

Interactive booklet reduces antibiotic prescribing for respiratory tract infections in children, but not parent satisfaction

Interactive booklet reduces antibiotic prescribing for respiratory tract infections in children, but not parent satisfaction

scientific article published in February 2010

Investigation of continuous effect modifiers in a meta-analysis on higher versus lower PEEP in patients requiring mechanical ventilation--protocol of the ICEM study

scientific article

Is a subgroup effect believable? Updating criteria to evaluate the credibility of subgroup analyses

scientific article published on 30 March 2010

Is procalcitonin determination for control of antibiotic therapy in acute respiratory infections of value?

scientific article published in March 2013

KVLQT channels are inhibited by the K+ channel blocker 293B.

scientific article

LOST to follow-up Information in Trials (LOST-IT): a protocol on the potential impact

scientific article

Learning from failure--rationale and design for a study about discontinuation of randomized trials (DISCO study).

scientific article

Meta-analyses: what they can and cannot do.

scientific article

Meta-analysis comparing Mediterranean to low-fat diets for modification of cardiovascular risk factors

scientific article

Methodological survey of designed uneven randomization trials (DU-RANDOM): a protocol

scientific article published on 23 January 2014

Methods for detecting, quantifying, and adjusting for dissemination bias in meta-analysis are described

scientific article

Mortality in randomized controlled trials comparing drug-eluting vs. bare metal stents in coronary artery disease: a meta-analysis

scientific article published on 4 October 2006

Mould-active compared with fluconazole prophylaxis to prevent invasive fungal diseases in cancer patients receiving chemotherapy or haematopoietic stem-cell transplantation: a systematic review and meta-analys

scientific article

Multivariable fractional polynomial interaction to investigate continuous effect modifiers in a meta-analysis on higher versus lower PEEP for patients with ARDS

scientific article published on 08 September 2016

Niacin for primary and secondary prevention of cardiovascular events

scientific article

Niacin for primary and secondary prevention of cardiovascular events.

scientific article

No evidence for direct activation of the cystic fibrosis transmembrane conductance regulator by 8-cyclopentyl-1,3-dipropylxanthine

scientific article published on January 1998

Nutritional Support and Outcomes in Malnourished Medical Inpatients: A Systematic Review and Meta-analysis

scientific article

Obtaining and managing data sets for individual participant data meta-analysis: scoping review and practical guide

scientific article published on 12 May 2020

Painting by number--Survival curves and Kaplan-Meier method

scientific article

Planning and reporting of quality-of-life outcomes in cancer trials

Planning and reporting of quality-of-life outcomes in cancer trials.

scientific article

Potential impact on estimated treatment effects of information lost to follow-up in randomised controlled trials (LOST-IT): systematic review

scientific article published on 18 May 2012

Premature Discontinuation of Pediatric Randomized Controlled Trials: A Retrospective Cohort Study

scientific article published on 3 March 2017

Premature Discontinuation of Prospective Clinical Studies Approved by a Research Ethics Committee - A Comparison of Randomised and Non-Randomised Studies

scientific article

Premature Discontinuation of Randomized Trials in Critical and Emergency Care: A Retrospective Cohort Study

scientific article published on 14 October 2015

Premature trial discontinuation often not accurately reflected in registries: comparison of registry records with publications

scientific article published on 7 September 2016

Prescribed medications and pharmacy interventions for acute respiratory tract infections in Swiss primary care

article

Prevalence and influence of diagnostic tests for acute respiratory tract infections in primary care

scientific article published on 01 April 2006

Prevalence, characteristics, and publication of discontinued randomized trials

scientific article published on March 2014

Pro-Adrenomedullin predicts 10-year all-cause mortality in community-dwelling patients: a prospective cohort study

scientific article

Problems of stopping trials early

scientific article published on 15 June 2012

Procalcitonin algorithms for antibiotic therapy decisions: a systematic review of randomized controlled trials and recommendations for clinical algorithms

scientific article

Procalcitonin to guide initiation and duration of antibiotic treatment in acute respiratory infections: an individual patient data meta-analysis

scientific article

Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections

scientific article

Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections

scientific article published on July 2013

Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections.

scientific article published on 13 October 2017

Procalcitonin to initiate or withhold antibiotics in acute respiratory tract infections

scientific article

Procalcitonin-Guided Antibiotic Use vs a Standard Approach for Acute Respiratory Tract Infections in Primary Care

article by Matthias Briel et al published 13 October 2008 in JAMA Internal Medicine

Procalcitonin-guided antibiotic therapy algorithms for different types of acute respiratory infections based on previous trials

scientific article published on 3 July 2018

Prognostic value of procalcitonin in respiratory tract infections across clinical settings

scientific article

Prospective analysis of adrenal function in patients with acute exacerbations of COPD: the Reduction in the Use of Corticosteroids in Exacerbated COPD (REDUCE) trial

scientific article

Publication bias in animal research: a systematic review protocol

scientific article published on 27 April 2013

Randomisation to protect against selection bias in healthcare trials

scientific article (publication date: 13 April 2011)

Randomized trials addressing a similar question are commonly published after a trial stopped early for benefit

scientific article

Randomized trials published in higher vs. lower impact journals differ in design, conduct, and analysis

article

Randomized trials stopped early for benefit: a systematic review

scientific article

Rationale and design of repeated cross-sectional studies to evaluate the reporting quality of trial protocols: the Adherence to SPIrit REcommendations (ASPIRE) study and associated projects

scientific article published on 28 October 2020

Reflections on meta-analyses involving trials stopped early for benefit: is there a problem and if so, what is it?

scientific article published on 13 December 2011

Reply to Stern, et al

scientific article published in 2018

Reply: Somatostatin Receptor-Targeted Radiopeptide Therapy in Patients with Progressive Unresectable Meningioma

scientific article published on 30 June 2016

Reporting Quality of Journal Abstracts for Surgical Randomized Controlled Trials Before and After the Implementation of the CONSORT Extension for Abstracts

scientific article published on 20 June 2019

Reporting of methodological studies in health research: a protocol for the development of the MethodologIcal STudy reportIng Checklist (MISTIC)

scientific article published on 17 December 2020

Reporting, handling and assessing the risk of bias associated with missing participant data in systematic reviews: a methodological survey

scientific article

Resource use, costs, and approval times for planning and preparing a randomized clinical trial before and after the implementation of the new Swiss human research legislation

scientific article published in PLoS ONE

Response by authors

scientific article published in July 2013

Response, survival, and long-term toxicity after therapy with the radiolabeled somatostatin analogue [90Y-DOTA]-TOC in metastasized neuroendocrine cancers

scientific article

Retrospective assessment of resource use and costs in two investigator-initiated randomised trials exemplified a comprehensive cost item list

scientific article published on 29 December 2017

Shared-decision making in general practice: do patients with respiratory tract infections actually want it?

article

Short versus conventional term glucocorticoid therapy in acute exacerbation of chronic obstructive pulmonary disease - the "REDUCE" trial

scientific article published on 18 October 2010

Short-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE randomized clinical trial

scientific article published on June 2013

Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies

scientific article published on 31 May 2019

Somatostatin receptor-targeted radiopeptide therapy with 90Y-DOTATOC and 177Lu-DOTATOC in progressive meningioma: long-term results of a phase II clinical trial.

scientific article

Somatostatin-based radiopeptide therapy with [177Lu-DOTA]-TOC versus [90Y-DOTA]-TOC in neuroendocrine tumours

scientific article

Somatostatin-based radiotherapy with [90Y-DOTA]-TOC in neuroendocrine tumors: long-term outcome of a phase I dose escalation study

scientific article published on 15 January 2013

Specific instructions for estimating unclearly reported blinding status in randomized trials were reliable and valid

scientific article published on 24 December 2011

Statin therapy for prevention and treatment of acute and chronic cardiovascular disease: update on recent trials and metaanalyses

scientific article

Statins for acute coronary syndrome

scientific article (publication date: September 2014)

Statins for acute coronary syndrome

scientific article (publication date: 14 June 2011)

Statins for acute coronary syndrome

scientific article

Statins: pleiotropic, but less than previously thought

article by A. J. Nordmann & Matthias Briel published 4 June 2012 in European Heart Journal

Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis

scientific article published on March 2010

Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2)

scientific article published on 06 July 2009

Subgroup Analysis of Trials Is Rarely Easy (SATIRE): a study protocol for a systematic review to characterize the analysis, reporting, and claim of subgroup effects in randomized trials

scientific article

Subgroup analyses in randomised controlled trials: cohort study on trial protocols and journal publications

scientific article

Subgroup analyses in randomised controlled trials: cohort study on trial protocols and journal publications

scientific article published in the British Medical Journal

Substitutes of structural and non-structural autologous bone grafts in hindfoot arthrodeses and osteotomies: a systematic review

scientific article

Survival after somatostatin based radiopeptide therapy with (90)Y-DOTATOC vs. (90)Y-DOTATOC plus (177)Lu-DOTATOC in metastasized gastrinoma

scientific article

Systematic review finds that study data not published in full text articles have unclear impact on meta-analyses results in medical research

scientific article

Systematic review of reviews including animal studies addressing therapeutic interventions for sepsis

scientific article published on December 2010

Systematic review on costs and resource use of randomised clinical trials shows a lack of transparent and comprehensive data

scientific article published on 26 December 2017

Systematic reviewers neglect bias that results from trials stopped early for benefit

scientific article

Systematic reviews do not adequately report or address missing outcome data in their analyses: a methodological survey

scholarly article by Lara A. Kahale et al published July 2018 in Journal of Clinical Epidemiology

Systematic reviews experience major limitations in reporting absolute effects

scientific article

The Clinical Effectiveness of Pneumococcal Conjugate Vaccines: A Systematic Review and Meta-analysis of Randomized Controlled Trials

scientific article published on March 2016

The Khorana score for prediction of venous thromboembolism in cancer patients: an individual patient data meta-analysis

scientific article published on 26 April 2020

The cystic fibrosis transmembrane conductance regulator attenuates the endogenous Ca2+ activated Cl- conductance of Xenopus oocytes

scientific article published in December 1997

The dangers of stopping a trial too early

scientific article published on July 2012

The fragility of trial results involves more than statistical significance alone

scientific article published on 13 April 2020

The impact of 18F-FDG PET on the management of patients with suspected large vessel vasculitis

scientific article published on 10 November 2011

The influence of study characteristics on reporting of subgroup analyses in randomised controlled trials: systematic review

scientific article published on 28 March 2011

The natriuretic peptide MR-proANP predicts all-cause mortality and adverse outcome in community patients: a 10-year follow-up study

scientific article published on 20 January 2017

The prognostic and predictive value of sstr2-immunohistochemistry and sstr2-targeted imaging in neuroendocrine tumors

scientific article published on 18 August 2016

The pylorus: take it or leave it? Systematic review and meta-analysis of pylorus-preserving versus standard whipple pancreaticoduodenectomy for pancreatic or periampullary cancer

scientific article published on 8 March 2007

The reporting of studies using routinely collected health data was often insufficient

scientific article

The sensitivity and specificity of the mannitol bronchial challenge test to identify asthma in different populations: a systematic review

scientific article published on 01 August 2019

Therapeutic Options for Neuroendocrine Tumors: A Systematic Review and Network Meta-analysis

scientific article published on 01 April 2019

Towards tailored radiopeptide therapy

scientific article published on 20 March 2015

Towards the development of a comprehensive framework: Qualitative systematic survey of definitions of clinical research quality

scientific article

Trial Forge Guidance 2: how to decide if a further Study Within A Trial (SWAT) is needed

scientific article published on 07 January 2020

Uncertainties about the need for ethics approval in Switzerland: a mixed-methods study

scientific article published on 12 August 2020

Updated evidence on early statin therapy for acute coronary syndromes: meta-analysis of 18 randomized trials involving over 14,000 patients

scientific article published on 04 February 2011

Use of heparins in patients with cancer: individual participant data meta-analysis of randomised trials study protocol

scientific article

Vasopressor administration and sepsis: a survey of Canadian intensivists

scientific article published on 30 March 2011

Why bother with regression models?

scientific article

[About the certainty of study results. What p-value and confidence intervalls tell us on it]

scientific article published on 01 April 2015

[Four numbers and basic knowledge of mathematics]

scientific article published on 01 January 2015

[Instructions for aggregated evidence: Systematic reviews and meta-analyses (part 1)]

article

[The number needed to treat (NNT) and the number needed to harm (NNH)]

scientific article published on 01 March 2015

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