A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self-renewal.

scientific article

A circuit motif in the zebrafish hindbrain for a two alternative behavioral choice to turn left or right

scientific article

A mathematical model relating cortical oxygenated and deoxygenated hemoglobin flows and volumes to neural activity

scientific article published on 5 June 2015

A multivariate network analysis of ring- and diffuse-porous tree xylem vasculature segmented by convolutional neural networks

Ablation of the Mauthner Cell Lateral Dendrite using Femtosecond Laser Pulses

Age-related intimal stiffening enhances endothelial permeability and leukocyte transmigration

scientific article published on December 2011

All-optical thrombotic stroke model for near-surface blood vessels in rat: focal illumination of exogeneous photosensitizers combined with real-time two-photon imaging

An intravital window to image the colon in real time

scientific article published on 11 December 2019

Applying optical imaging to study neurovascular coupling in cerebral cortex: from populational scale to single-cell single-vessel measurements

Big effects from tiny vessels: imaging the impact of microvascular clots and hemorrhages on the brain

scientific article published on June 2013

Causes and consequences of baseline cerebral blood flow reductions in Alzheimer's disease

Circumscribing laser cuts attenuate seizure propagation in a mouse model of focal epilepsy

Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.

scientific article

Cortical microhemorrhages cause local inflammation but do not trigger widespread dendrite degeneration

scientific article (publication date: 2011)

Deep tissue multiphoton microscopy using longer wavelength excitation

scientific article published in August 2009

Dynamics of femtosecond laser-induced breakdown in water from femtoseconds to microseconds.

scientific article

Endothelial cells promote 3D invasion of GBM by IL-8-dependent induction of cancer stem cell properties

scientific article published on 21 June 2019

Experimentally constrained circuit model of cortical arteriole networks for understanding flow redistribution due to occlusion and neural activation.

scientific article published in January 2017

Femtosecond Laser Ablation to Induce Occlusions in Single, Targeted Venules in Rat Brain

Femtosecond Laser-Driven Photodisruption to Induce Single Venule Occlusions in Rodent Brain

Femtosecond Laser-Induced Microvascular Clots Trigger Alzheimer’s Disease Pathology

scholarly article published 2008

Flexible microfluidic devices supported by biodegradable insertion scaffolds for convection-enhanced neural drug delivery

scientific article published in August 2009

Growth and hemodynamics after early embryonic aortic arch occlusion

scientific article

Higher-Order Multiphoton Microscopy of the Beating Mouse Heart Using Resonant Scanning

Hyperspectral multiphoton microscopy for visualization of multiple, spectrally overlapped fluorescent labels

Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations

scientific article

In Vivo Three-photon Calcium Imaging of Brain Activity from Layer 6 Neurons in Mouse Brain

In vivo Three-photon Imaging of Brain Activity from Cortical and Subcortical Neurons in Intact Mouse Brain

In vivo deep tissue imaging with long wavelength multiphoton excitation

In vivo manipulation of biological systems with femtosecond laser pulses

In vivo three-photon activity imaging of GCaMP6-labeled neurons in deep cortex and the hippocampus of the mouse brain

In vivo three-photon imaging of activity of GCaMP6-labeled neurons deep in intact mouse brain.

scientific article

In vivo two-photon excited fluorescence microscopy reveals cardiac- and respiration-dependent pulsatile blood flow in cortical blood vessels in mice

scientific article published on 20 January 2012

In-Vivo Imaging of Beating Mouse Heart with Multiphoton Microscopy

In-Vivo Three-Photon Excited Fluorescence Imaging in the Spinal Cord of Awake, Locomoting Mouse

Intestinal crypts recover rapidly from focal damage with coordinated motion of stem cells that is impaired by aging

scientific article published on 20 July 2018

Label-Free Detection of Atherosclerotic Plaque Formation Using Third Harmonic Generation Microscopy

Label-free imaging of atherosclerotic plaques using third-harmonic generation microscopy

scientific article

Laser photoablation: a new biomedical tool

Laser-induced microexplosions in transparent materials: microstructuring with nanojoules

Limitations of collateral flow after occlusion of a single cortical penetrating arteriole

scientific article

Little Channels, Big Disease: Using Microfluidics to Investigate Cancer Metastasis

Mechanistic insight into the TH1-biased immune response to recombinant subunit vaccines delivered by probiotic bacteria-derived outer membrane vesicles

scientific article

Microvessel occlusions alter amyloid-beta plaque morphology in a mouse model of Alzheimer's disease

scientific article published on 19 November 2019

Multicolor Genetically-Encoded Calcium-Sensitive Bioluminescent Reporters of Neural Activity for Brain-Machine Interfaces

Neurological and Inflammatory Effects of Radio Frequency and Cryoablation in a Rat Sciatic Nerve Model of Submucosal Nerve Ablation

Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer's disease mouse models

scientific article published on 11 February 2019

Nonlinear Optical Tools for Studying Small-Stroke at Microscopic Scales

Occlusion of cortical ascending venules causes blood flow decreases, reversals in flow direction, and vessel dilation in upstream capillaries.

scientific article

Optically induced occlusion of single blood vessels in rodent neocortex

scientific article

Optoporation and genetic manipulation of cells using femtosecond laser pulses.

scientific article

Penetrating arterioles are a bottleneck in the perfusion of neocortex

scientific article

Preictal and ictal neurovascular and metabolic coupling surrounding a seizure focus

scientific article

Principles, Design,and Construction of a Two-Photon Laser-Scanning Microscopefor In Vitro and In Vivo Brain Imaging

Real-time imaging of perivascular transport of nanoparticles during convection-enhanced delivery in the rat cortex.

scientific article published on 19 October 2011

Robust and fragile aspects of cortical blood flow in relation to the underlying angioarchitecture

scientific article

Simultaneous optical and electrical in vivo analysis of the enteric nervous system

scientific article

Stalled cerebral capillary blood flow in mouse models of essential thrombocythemia and polycythemia vera revealed by in vivo two-photon imaging.

scientific article

Stimulus-Evoked Calcium Transients in Somatosensory Cortex are Inhibited After a Nearby Microhemorrhage

Stimulus-evoked calcium transients in somatosensory cortex are temporarily inhibited by a nearby microhemorrhage.

scientific article

Sub-surface, micrometer-scale incisions produced in rodent cortex using tightly-focused femtosecond laser pulses

scientific article

Suppressed neuronal activity and concurrent arteriolar vasoconstriction may explain negative blood oxygenation level-dependent signal

scientific article published on April 2007

Targeted disruption of deep-lying neocortical microvessels in rat using ultrashort laser pulses

Targeted insult to subsurface cortical blood vessels using ultrashort laser pulses: three models of stroke

scientific article published in February 2006

The inflammatory response following a laser-induced cortical microhemorrhage in a rodent model is dominated by brain-resident microglia and not blood-borne macrophages

Three-Photon Excited Fluorescence Imaging of Unstained Tissue Using a GRIN Endoscope

Three-photon excited fluorescence imaging of unstained tissue using a GRIN lens endoscope.

scientific article published on April 2013

Thresholds for femtosecond laser-induced breakdown in bulk transparent solids and water

Two-Photon Imaging Reveals Capillary Occlusions are Responsible for Reduced Brain Blood Flow and Cognitive Decline in Alzheimer’s Disease Mouse Models

Two-Photon Imaging of Cortical Microvascular Blood Flow in Response to Single Vessel Occlusion

Two-Photon Microscopy as a Tool to Study Blood Flow and Neurovascular Coupling in the Rodent Brain

Two-photon fluorescence microscopy of collateral blood flow following photothrombotic stroke in rat neocortex

Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion.

scientific article

Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain

scientific article

Two-photon microscopy-guided femtosecond-laser photoablation of avian cardiogenesis: noninvasive creation of localized heart defects.

scientific article

Ultrafast laser-induced microexplosions: explosive dynamics and submicrometer structures

article

Understanding the Dynamics of the Stem Cell Niche in the Small Intestine with Femtosecond Laser Photodisruption

Use of Tethered Enzymes as a Platform Technology for Rapid Analyte Detection

scientific article published on 25 November 2015