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List of works by Cristian G. Bologa

A Potent and Selective Inhibitor of Cdc42 GTPase

A Selective Ligand for Estrogen Receptor Proteins Discriminates Rapid and Genomic Signaling

scientific article published on 06 November 2019

A comprehensive map of molecular drug targets.

scientific article published on 2 December 2016

A crowdsourcing evaluation of the NIH chemical probes

scientific article (publication date: July 2009)

A high throughput flow cytometric assay platform targeting transporter inhibition

scientific article

A novel flow cytometric HTS assay reveals functional modulators of ATP binding cassette transporter ABCB6

scientific article

A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry

scientific article

A small molecule pan-inhibitor of Ras-superfamily GTPases with high efficacy towards Rab7

Activation of Rho Family GTPases by Small Molecules.

scientific article

An automated PLS search for biologically relevant QSAR descriptors

scientific article published in July 2004

Associating Drugs, Targets and Clinical Outcomes into an Integrated Network Affords a New Platform for Computer-Aided Drug Repurposing.

scientific article published on March 2011

Badapple: promiscuity patterns from noisy evidence

scientific article

Biomolecular screening of formylpeptide receptor ligands with a sensitive, quantitative, high-throughput flow cytometry platform

CHEMICAL AND BIOLOGICAL DESCRIPTOR INTEGRATION IMPROVES COMPUTATIONAL MODELING OF IN VIVO RAT TOXICITY.

scientific article

Chemical database preparation for compound acquisition or virtual screening

scientific article published in January 2006

Cheminformatics aspects of high throughput screening: from robots to models: symposium summary

scientific article

Compound Collection Preparation for Virtual Screening ⬇️

scientific article published on 01 January 2012

Conformational mAb as a tool for integrin ligand discovery

scientific article

Correlation between the predicted and the observed biological activity of the symmetric and nonsymmetric cyclic urea derivatives used as HIV‐1 protease inhibitors. A 3D‐QSAR‐CoMFA method for new antiviral drug design ⬇️

scientific article published on July 1, 2003

Defining the microbial effluxome in the content of the host-microbiome interaction

scientific article published on 19 February 2015

Descriptor collision and confusion: toward the design of descriptors to mask chemical structures

scientific article published in September 2005

Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system

scientific article

Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair

scientific article

Dissociation of I domain and global conformational changes in LFA-1: refinement of small molecule-I domain structure-activity relationships

scientific article

Drug Repurposing from an Academic Perspective

scientific article published on January 2011

Drug target ontology to classify and integrate drug discovery data

scientific article

DrugCentral 2018: an update

scientific article published in January 2019

DrugCentral 2021 supports drug discovery and repositioning

scientific article published on 05 November 2020

DrugCentral: online drug compendium

scientific article (publication date: 26 October 2016)

Duplex high-throughput flow cytometry screen identifies two novel formylpeptide receptor family probes

scientific article

Emerging trends in the discovery of natural product antibacterials

scientific article published on 24 July 2013

Erratum to: Impact of similarity threshold on the topology of molecular similarity networks and clustering outcomes

scientific article (publication date: 2016)

Erratum: A crowdsourcing evaluation of the NIH chemical probes

article

Exploring the biological promiscuity of high-throughput screening hits through DFT calculations

scientific article

FRET detection of lymphocyte function-associated antigen-1 conformational extension.

scientific article

Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters

scientific article

Formalizing drug indications on the road to therapeutic intent.

scientific article published in November 2017

High-Throughput Flow Cytometry

High-Throughput Flow Cytometry Screening of Multidrug Efflux Systems.

scientific article published in January 2018

High-throughput flow cytometry for drug discovery

scientific article published in May 2007

High-throughput screen for the chemical inhibitors of antiapoptotic bcl-2 family proteins by multiplex flow cytometry

scientific article

High-throughput screening with HyperCyt flow cytometry to detect small molecule formylpeptide receptor ligands

scientific article published in June 2005

Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs

scientific article

How many rare diseases are there?

scientific article published on 01 February 2020

How to Illuminate the Druggable Genome Using Pharos

scientific article published on 01 March 2020

How to Prepare a Compound Collection Prior to Virtual Screening

scientific article published on 01 January 2019

Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity

scientific article published on 14 July 2011

Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry

scientific article published in February 2012

Impact of similarity threshold on the topology of molecular similarity networks and clustering outcomes

scientific article

In vivo effects of a GPR30 antagonist

scientific article

Integration of virtual and physical screening

Integration of virtual screening with high-throughput flow cytometry to identify novel small molecule formylpeptide receptor antagonists

scientific article published on 23 August 2005

Lead-like, drug-like or "Pub-like": how different are they?

scientific article

Ligand-directed profiling of organelles with internalizing phage libraries

scientific article published on 2 February 2015

Ligand-directed targeting of lymphatic vessels uncovers mechanistic insights in melanoma metastasis

scientific article

MTD-PLS: A PLS-based variant of the MTD method. 2. Mapping ligand-receptor interactions. Enzymatic acetic acid esters hydrolysis

scientific article published on 01 July 2002

Microbial efflux pump inhibition: tactics and strategies

scientific article

Modulation of bitter taste perception by a small molecule hTAS2R antagonist

scientific article published on 27 May 2010

Of possible cheminformatics futures

scientific article

Pharos: Collating protein information to shed light on the druggable genome

scientific article

Phenylaziridine as a 1,3-dipole. Application to the synthesis of functionalized pyrrolidines

Post-high-throughput screening analysis: an empirical compound prioritization scheme

scientific article published in August 2005

Profiling a Selective Probe for RTG Branch of Yeast TORC1 Signaling Pathway

scientific article published on 10 May 2013

Protein biomarker druggability profiling.

scientific article published on 25 January 2017

Quantitative structure-activity relationship by CoMFA for cyclic urea and nonpeptide-cyclic cyanoguanidine derivatives on wild type and mutant HIV-1 protease

scientific article published on 16 February 2005

Real-time analysis of conformation-sensitive antibody binding provides new insights into integrin conformational regulation

scientific article

Selective Efflux Inhibition of ATP-binding Cassette Sub-family G Member 2

scientific article published on 10 May 2013

Significance of MTD and other descriptors in lipophilicity models for chlorinated aromatic compounds

scientific article published in January 2001

Strategies for compound selection

scientific article

Structural determinants of the alpha2 adrenoceptor subtype selectivity

scientific article published on 6 May 2011

Structural simplification of bioactive natural products with multicomponent synthesis. 3. Fused uracil-containing heterocycles as novel topoisomerase-targeting agents

scientific article

TCRD and Pharos 2021: mining the human proteome for disease biology

scientific article published on 06 November 2020

TIN-X: target importance and novelty explorer

scientific article published on 07 April 2017

The CARLSBAD database: a confederated database of chemical bioactivities

scientific article published on 21 June 2013

Therapeutic options and emerging alternatives for multidrug resistant staphylococcal infections

scientific article

Three small molecule pan activator families of Ras-related GTPases

Unexplored therapeutic opportunities in the human genome

scientific article published on 23 March 2018

Unexplored therapeutic opportunities in the human genome.

scientific article published on 23 February 2018

Virtual and <i>In Vitro</i> Antiviral Screening Revive Therapeutic Drugs for COVID-19

scientific article published on 14 October 2020

Virtual and biomolecular screening converge on a selective agonist for GPR30.

scientific article published on 5 March 2006

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