List of works - Nick R Lemoine

A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia

scientific article published on 01 August 2018

A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors.

scientific article published on 30 October 2016

A Virus-Infected, Reprogrammed Somatic Cell-Derived Tumor Cell (VIReST) Vaccination Regime Can Prevent Initiation and Progression of Pancreatic Cancer

scientific article published on 25 November 2019

A global insight into a cancer transcriptional space using pancreatic data: importance, findings and flaws.

scientific article

A marker-free system for highly efficient construction of vaccinia virus vectors using CRISPR Cas9.

scientific article

A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma

scientific article

A novel therapeutic regimen to eradicate established solid tumors with an effective induction of tumor-specific immunity.

scientific article published on 22 October 2012

A practical guide for the functional annotation of genetic variations using SNPnexus

scientific article published on 8 February 2013

A vaccinia virus armed with interleukin-10 is a promising therapeutic agent for treatment of murine pancreatic cancer

scientific article published on 21 November 2014

AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and D

scientific article

Adenovirus-mediated sensitization to the cytotoxic drugs docetaxel and mitoxantrone is dependent on regulatory domains in the E1ACR1 gene-region

scientific article

An oncolytic adenovirus defective in pRb-binding (dl922-947) can efficiently eliminate pancreatic cancer cells and tumors in vivo in combination with 5-FU or gemcitabine.

scientific article

Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma

scientific article published on 07 April 2016

Arginine deprivation and argininosuccinate synthetase expression in the treatment of cancer.

scientific article published on June 2010

CRISPR-Cas9 as a Powerful Tool for Efficient Creation of Oncolytic Viruses

scientific article

Combination of anti-angiogenic therapy and virotherapy: arming oncolytic viruses with anti-angiogenic genes.

scientific article published on December 2009

Distinct genomic alterations in prostate cancers in Chinese and Western populations suggest alternative pathways of prostate carcinogenesis.

scientific article published on June 2010

ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation

scientific article published on 12 December 2016

Efficacy of oncolytic mutants targeting pRb and p53 pathways is synergistically enhanced when combined with cytotoxic drugs in prostate cancer cells and tumor xenografts

scientific article

Efficiently editing the vaccinia virus genome by using the CRISPR-Cas9 system. ⬇️

scientific article

Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma

scientific article

Immune-checkpoint blockade: the springboard for immuno-combination therapy.

scientific article

Improved potency and selectivity of an oncolytic E1ACR2 and E1B19K deleted adenoviral mutant in prostate and pancreatic cancers

scientific article

Lister strain vaccinia virus with thymidine kinase gene deletion is a tractable platform for development of a new generation of oncolytic virus.

scientific article

Lister strain vaccinia virus, a potential therapeutic vector targeting hypoxic tumours

scientific article

Lister vaccine strain of vaccinia virus armed with the endostatin-angiostatin fusion gene: an oncolytic virus superior to dl1520 (ONYX-015) for human head and neck cancer

scientific article published on 18 April 2011

MHC class II molecules on pancreatic cancer cells indicate a potential for neo-antigen-based immunotherapy

scientific article published on 27 May 2022

Modification of the early gene enhancer-promoter improves the oncolytic potency of adenovirus 11.

scientific article

New role of Interleukin-10 in enhancing the antitumor efficacy of oncolytic vaccinia virus for treatment of pancreatic cancer

scientific article

Novel therapies for pancreatic cancer: setbacks and progress

scientific article published on July 2010

Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion

scientific article published on 06 February 2014

O-miner: an integrative platform for automated analysis and mining of -omics data.

scientific article

PRSS3 promotes tumour growth and metastasis of human pancreatic cancer

scientific article published on November 2010

Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging

scientific article published on 27 November 2013

S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells.

scientific article

STAT1 interaction with E3-14.7K in monocytes affects the efficacy of oncolytic adenovirus

scientific article published on 11 December 2013

Synergistic and Selective Cancer Cell Killing Mediated by the Oncolytic Adenoviral Mutant AdΔΔ and Dietary Phytochemicals in Prostate Cancer Models

scientific article

Targeted radionuclide therapy using a Wnt-targeted replicating adenovirus encoding the Na/I symporter.

scientific article published on 27 October 2009

The E1B19K-deleted oncolytic adenovirus mutant AdΔ19K sensitizes pancreatic cancer cells to drug-induced DNA-damage by down-regulating Claspin and Mre11

scientific article

The fibroblast growth factor receptor inhibitor PD173074 blocks small cell lung cancer growth in vitro and in vivo.

scientific article published on 10 November 2009

The oncolytic adenovirus AdΔΔ enhances selective cancer cell killing in combination with DNA-damaging drugs in pancreatic cancer models

scientific article published on 6 October 2011

The pancreatic expression database: recent extensions and updates

scientific article

Update on oncolytic viral therapy - targeting angiogenesis

scientific article published on 31 July 2013

Using BioMart as a framework to manage and query pancreatic cancer data.

scientific article

Vaccinia virus, a promising new therapeutic agent for pancreatic cancer

scientific article

Vascular endothelial growth factor A promotes vaccinia virus entry into host cells via activation of the Akt pathway.

scientific article

List of works by Nick R Lemoine

A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia

A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors.

A Virus-Infected, Reprogrammed Somatic Cell-Derived Tumor Cell (VIReST) Vaccination Regime Can Prevent Initiation and Progression of Pancreatic Cancer

A global insight into a cancer transcriptional space using pancreatic data: importance, findings and flaws.

A marker-free system for highly efficient construction of vaccinia virus vectors using CRISPR Cas9.

A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma

A novel therapeutic regimen to eradicate established solid tumors with an effective induction of tumor-specific immunity.

A practical guide for the functional annotation of genetic variations using SNPnexus

A vaccinia virus armed with interleukin-10 is a promising therapeutic agent for treatment of murine pancreatic cancer

AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and D

Adenovirus-mediated sensitization to the cytotoxic drugs docetaxel and mitoxantrone is dependent on regulatory domains in the E1ACR1 gene-region

An oncolytic adenovirus defective in pRb-binding (dl922-947) can efficiently eliminate pancreatic cancer cells and tumors in vivo in combination with 5-FU or gemcitabine.

Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma

Arginine deprivation and argininosuccinate synthetase expression in the treatment of cancer.

CRISPR-Cas9 as a Powerful Tool for Efficient Creation of Oncolytic Viruses

Combination of anti-angiogenic therapy and virotherapy: arming oncolytic viruses with anti-angiogenic genes.

Distinct genomic alterations in prostate cancers in Chinese and Western populations suggest alternative pathways of prostate carcinogenesis.

ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation

Efficacy of oncolytic mutants targeting pRb and p53 pathways is synergistically enhanced when combined with cytotoxic drugs in prostate cancer cells and tumor xenografts

Efficiently editing the vaccinia virus genome by using the CRISPR-Cas9 system. ⬇️

Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma

Immune-checkpoint blockade: the springboard for immuno-combination therapy.

Improved potency and selectivity of an oncolytic E1ACR2 and E1B19K deleted adenoviral mutant in prostate and pancreatic cancers

Lister strain vaccinia virus with thymidine kinase gene deletion is a tractable platform for development of a new generation of oncolytic virus.

Lister strain vaccinia virus, a potential therapeutic vector targeting hypoxic tumours

Lister vaccine strain of vaccinia virus armed with the endostatin-angiostatin fusion gene: an oncolytic virus superior to dl1520 (ONYX-015) for human head and neck cancer

MHC class II molecules on pancreatic cancer cells indicate a potential for neo-antigen-based immunotherapy

Modification of the early gene enhancer-promoter improves the oncolytic potency of adenovirus 11.

New role of Interleukin-10 in enhancing the antitumor efficacy of oncolytic vaccinia virus for treatment of pancreatic cancer

Novel therapies for pancreatic cancer: setbacks and progress

Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion

O-miner: an integrative platform for automated analysis and mining of -omics data.

PRSS3 promotes tumour growth and metastasis of human pancreatic cancer

Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging

S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells.

STAT1 interaction with E3-14.7K in monocytes affects the efficacy of oncolytic adenovirus

Synergistic and Selective Cancer Cell Killing Mediated by the Oncolytic Adenoviral Mutant AdΔΔ and Dietary Phytochemicals in Prostate Cancer Models

Targeted radionuclide therapy using a Wnt-targeted replicating adenovirus encoding the Na/I symporter.

The E1B19K-deleted oncolytic adenovirus mutant AdΔ19K sensitizes pancreatic cancer cells to drug-induced DNA-damage by down-regulating Claspin and Mre11

The fibroblast growth factor receptor inhibitor PD173074 blocks small cell lung cancer growth in vitro and in vivo.

The oncolytic adenovirus AdΔΔ enhances selective cancer cell killing in combination with DNA-damaging drugs in pancreatic cancer models

The pancreatic expression database: recent extensions and updates

Update on oncolytic viral therapy - targeting angiogenesis

Using BioMart as a framework to manage and query pancreatic cancer data.

Vaccinia virus, a promising new therapeutic agent for pancreatic cancer

Vascular endothelial growth factor A promotes vaccinia virus entry into host cells via activation of the Akt pathway.