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List of works by Flavio Curnis

A new chromogranin A-dependent angiogenic switch activated by thrombin

scientific article published on 27 November 2012

A stapled chromogranin A-derived peptide is a potent dual ligand for integrins αvβ6 and αvβ8

scientific article published on 01 December 2019

Biotinylation sites of tumor necrosis factor-alpha determined by liquid chromatography-mass spectrometry

scientific article published in November 2001

Boosting Interleukin-12 Antitumor Activity and Synergism with Immunotherapy by Targeted Delivery with isoDGR-Tagged Nanogold

scientific article published on 16 September 2019

Ceruloplasmin functional changes in Parkinson's disease-cerebrospinal fluid

scientific article published on 4 November 2015

Chromogranin A Is Preferentially Cleaved into Proangiogenic Peptides in the Bone Marrow of Multiple Myeloma Patients

scientific article published on 11 February 2016

Chromogranin A binds to αvβ6-integrin and promotes wound healing in mice

scientific article published on 14 March 2012

Chromogranin A restricts drug penetration and limits the ability of NGR-TNF to enhance chemotherapeutic efficacy.

scientific article

Cleavage of chromogranin A N-terminal domain by plasmin provides a new mechanism for regulating cell adhesion

scientific article

Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma

scientific article published on 24 March 2010

Coupling tumor necrosis factor-alpha with alphaV integrin ligands improves its antineoplastic activity

scientific article published on January 2004

Critical role of flanking residues in NGR-to-isoDGR transition and CD13/integrin receptor switching

scientific article published on 11 January 2010

Critical role of indoleamine 2,3-dioxygenase in tumor resistance to repeated treatments with targeted IFNgamma

scientific article

Crucial role for interferon gamma in the synergism between tumor vasculature-targeted tumor necrosis factor alpha (NGR-TNF) and doxorubicin

scientific article

Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13).

scientific article

Immunogenic and structural properties of the Asn-Gly-Arg (NGR) tumor neovasculature-homing motif

Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration

article

IsoDGR-tagged albumin: a new αvβ3 selective carrier for nanodrug delivery to tumors

scientific article published on 12 November 2012

Isoaspartate-dependent molecular switches for integrin–ligand recognition ⬇️

scientific article published on February 15, 2011

Isoaspartate-glycine-arginine: a new tumor vasculature-targeting motif

scientific article published in September 2008

Myocardial production of chromogranin A in human heart: a new regulatory peptide of cardiac function

scientific article published on 27 March 2007

NGR-tagged nano-gold: A new CD13-selective carrier for cytokine delivery to tumors

scientific article published on 04 March 2016

Neuroblastoma-targeted nanocarriers improve drug delivery and penetration, delay tumor growth and abrogate metastatic diffusion

scientific article published on August 2015

Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings.

scientific article

Oxidation-induced structural changes of ceruloplasmin foster NGR motif deamidation that promotes integrin binding and signaling

scientific article published on 23 December 2013

Peptide-mediated targeting of cytokines to tumor vasculature: the NGR-hTNF example.

scientific article published on December 2013

R-CHOP preceded by blood-brain barrier permeabilization with engineered tumor necrosis factor-α in primary CNS lymphoma

scientific article published on 22 May 2019

Role of vasostatin-1 C-terminal region in fibroblast cell adhesion.

scientific article published on 9 March 2010

Selective imaging of the angiogenic relevant integrins α5β1 and αvβ3.

scientific article

Spatiotemporal Regulation of Tumor Angiogenesis by Circulating Chromogranin A Cleavage and Neuropilin-1 Engagement

scientific article published on 22 February 2019

Spontaneous formation of L-isoaspartate and gain of function in fibronectin.

scientific article published on 2 October 2006

Structural basis for the interaction of isoDGR with the RGD-binding site of alphavbeta3 integrin

scientific article

Structure-activity relationships of chromogranin A in cell adhesion. Identification of an adhesion site for fibroblasts and smooth muscle cells

scientific article published on September 2000

Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif

scientific article published on 7 October 2002

Synergistic antitumor activity of cisplatin, paclitaxel, and gemcitabine with tumor vasculature-targeted tumor necrosis factor-alpha

scientific article published in January 2006

Synergistic damage of tumor vessels with ultra low-dose endothelial-monocyte activating polypeptide-II and neovasculature-targeted tumor necrosis factor-alpha

scientific article published in February 2008

T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors.

scientific article

Targeted delivery of IFNgamma to tumor vessels uncouples antitumor from counterregulatory mechanisms

scientific article

Targeted drug delivery and penetration into solid tumors

scientific article published on February 2011

Targeting TNF- to Neoangiogenic Vessels Enhances Lymphocyte Infiltration in Tumors and Increases the Therapeutic Potential of Immunotherapy

scientific article published on 08 February 2012

Targeting Tumor Vasculature with TNF Leads Effector T Cells to the Tumor and Enhances Therapeutic Efficacy of Immune Checkpoint Blockers in Combination with Adoptive Cell Therapy

scientific article published on 28 February 2018

The neovasculature homing motif NGR: more than meets the eye.

scientific article published on 23 June 2008

Tumor Vasculature Targeting Through NGR Peptide-Based Drug Delivery Systems ⬇️

scientific article published on August 1, 2011

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