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List of works by Mirco Ponzoni

A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A.

scientific article published on 4 January 2017

A combined evaluation of biochemical and morphological changes during human neuroblastoma cell differentiation

scientific article

A new fluorescence-based optical imaging method to non-invasively monitor hepatic myofibroblasts in vivo

scientific article published on 8 April 2016

A novel liposomal Clodronate depletes tumor-associated macrophages in primary and metastatic melanoma: Anti-angiogenic and anti-tumor effects.

scientific article published on 29 December 2015

ALK-dependent control of hypoxia-inducible factors mediates tumor growth and metastasis.

scientific article published on 5 September 2014

An alternative in vivo system for testing angiogenic potential of human neuroblastoma cells

scientific article published on 17 January 2009

An interferon-sensitive response element is involved in constitutive caspase-8 gene expression in neuroblastoma cells.

scientific article published on January 2007

Angiogenesis and anti-angiogenesis in neuroblastoma.

scientific article

Angiogenesis extent and expression of matrix metalloproteinase-2 and -9 correlate with progression in human neuroblastoma

scientific article published on 01 January 2001

Angiogenesis in neuroblastoma.

scientific article

Anti-IL-10R antibody improves the therapeutic efficacy of targeted liposomal oligonucleotides

scientific article published on 7 May 2009

Anti-Tumor Effects of Bak-Proteoliposomes against Glioblastoma.

scientific article published on September 2015

Antiproliferative and pro-apoptotic activity of eugenol-related biphenyls on malignant melanoma cells

scientific article published on 18 January 2007

Autocrine regulation of volume-sensitive anion channels in airway epithelial cells by adenosine

scientific article published on April 1999

Bioavailability of antisense oligonucleotides in neuroblastoma cells: comparison of efficacy among different types of molecules.

scientific article published on January 1997

Caspase-8 gene expression in neuroblastoma.

scientific article

Chemopreventive N-(4-hydroxyphenyl)retinamide (fenretinide) targets deregulated NF-{kappa}B and Mat1A genes in the early stages of rat liver carcinogenesis

scientific article published on 21 October 2004

Chromogranin A Is Preferentially Cleaved into Proangiogenic Peptides in the Bone Marrow of Multiple Myeloma Patients

scientific article published on 11 February 2016

Chromogranin A binds to αvβ6-integrin and promotes wound healing in mice

scientific article published on 14 March 2012

Clinical impact of the NKp30/B7-H6 axis in high-risk neuroblastoma patients

scientific article

Cloning and sequencing of isoform-specific regions of human Ca2+-independent protein kinase C (PKC)-encoding genes.

scientific article published on April 1994

Coated cationic lipid-nanoparticles entrapping miR-660 inhibit tumor growth in patient-derived xenografts lung cancer models

scientific article published on 09 July 2019

Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma

scientific article published on 24 March 2010

Combined therapeutic effects of vinblastine and rapamycin on human neuroblastoma growth, apoptosis, and angiogenesis

scientific article

Critical role of flanking residues in NGR-to-isoDGR transition and CD13/integrin receptor switching

scientific article published on 11 January 2010

Development of Fab' fragments of anti-GD(2) immunoliposomes entrapping doxorubicin for experimental therapy of human neuroblastoma.

scientific article

Different regulation of mid-size neurofilament and N-myc mRNA expression during neuroblastoma cell differentiation induced by retinoic acid

scientific article published on September 1990

Differential changes in lipid metabolism of myeloid and lymphoid cell lines induced by treatment with 12-O-tetradecanoylphorbol-13-acetate (TPA).

scientific article published on December 1990

Discovery of a novel glucose metabolism in cancer: The role of endoplasmic reticulum beyond glycolysis and pentose phosphate shunt

scientific article published on 28 April 2016

Doxorubicin effect on myocardial metabolism as a pre-requisite for subsequent development of cardiac toxicity: a translational (18)F-FDG PET/CT observation.

scientific article published on 23 June 2017

Effect of bortezomib on human neuroblastoma cell growth, apoptosis, and angiogenesis

scientific article published on August 2006

Effects of gamma-interferon on the growth, morphology, and membrane and cytoskeletal proteins expression of Lan-1 cells

scientific article published in December 1989

Enhanced anti-tumor activity of a new curcumin-related compound against melanoma and neuroblastoma cells

scientific article

Enhanced anti-tumor and anti-angiogenic efficacy of a novel liposomal fenretinide on human neuroblastoma

scientific article published on 19 June 2013

Enhanced antitumor efficacy of clinical-grade vasculature-targeted liposomal doxorubicin

scientific article

Enhancement of Tumor Homing by Chemotherapy-Loaded Nanoparticles

scientific article published on 07 October 2018

Expression of DeltaNp73 is a molecular marker for adverse outcome in neuroblastoma patients

scientific article published on 01 March 2002

Expression of the caspase-8 gene in neuroblastoma cells is regulated through an essential interferon-sensitive response element (ISRE)

scientific article published on 01 January 2004

Fenretinide as an anti-angiogenic agent in neuroblastoma.

scientific article

Fibrin Gels Entrapment of a Poly-Cyclodextrin Nanocarrier as a Doxorubicin Delivery System in an Orthotopic Model of Neuroblastoma: Evaluation of In Vitro Activity and In Vivo Toxicity

scientific article published on 03 June 2019

Gamma-interferon and retinoic acid synergize in inhibiting the growth of human neuroblastoma cells in nude mice

scientific article

Gamma-interferon, retinoic acid, and cytosine arabinoside induce neuroblastoma differentiation by different mechanisms

scientific article published on 01 August 1991

Glycine N-methylation in NGR-Tagged Nanocarriers Prevents Isoaspartate formation and Integrin Binding without Impairing CD13 Recognition and Tumor Homing

scientific article published on September 2017

Gut Bacteria and their Metabolites: Which One Is the Defendant for Colorectal Cancer?

scientific article published on 13 November 2019

Immune evaluation of 50 children with neuroblastoma at onset

scientific article published on 01 January 1982

Immunogenic and structural properties of the Asn-Gly-Arg (NGR) tumor neovasculature-homing motif

Immunoliposomal fenretinide: a novel antitumoral drug for human neuroblastoma.

scientific article

In vitro and in vivo antitumor activity of liposomal Fenretinide targeted to human neuroblastoma.

scientific article published in May 2003

In vivo angiogenic activity of neuroblastoma correlates withMYCN oncogene overexpression

scientific article published on 01 December 2002

Increase of therapeutic effects by treating melanoma with targeted combinations of c-myc antisense and doxorubicin

scientific article published on 28 November 2007

Increased myocardial 18F-FDG uptake as a marker of Doxorubicin-induced oxidative stress

scientific article published on 08 February 2019

Induction of 2.5 OAS gene expression and activity is not sufficient for IFN-gamma-induced neuroblastoma cell differentiation.

scientific article published on July 1995

Inhibition of neuroblastoma-induced angiogenesis by fenretinide

scientific article

Interferon-gamma-induced differentiation of human neuroblastoma cells increases cellular uptake and halflife of metaiodobenzylguanidine

scientific article published on January 1993

Investigational drugs in phase II clinical trials for the treatment of neuroblastoma.

scientific article published on 14 September 2017

Ligand-targeted liposomal therapies of neuroblastoma.

scientific article published on January 2007

Liposome-mediated therapy of neuroblastoma

scientific article published in January 2009

Microfragmented human fat tissue is a natural scaffold for drug delivery: Potential application in cancer chemotherapy

scientific article published on 16 March 2019

Modulation of alpha 1 beta 1, alpha 2 beta 1 and alpha 3 beta 1 integrin heterodimers during human neuroblastoma cell differentiation

scientific article published on 01 October 1993

Molecular galactose-galectin association in neuroblastoma cells: An unconventional tool for qualitative/quantitative screening

scientific article

Morphologic and phenotypic changes of human neuroblastoma cells in culture induced by cytosine arabinoside

scientific article published on March 1989

Morphological and biochemical modifications during neuroblastoma cell differentiation

scientific article published on February 1991

N-(4-hydroxyphenyl) retinamide inhibits cystogenesis by polycystic epithelial cell lines in vitro

scientific article published on January 1999

Nanocarrier-mediated targeting of tumor and tumor vascular cells improves uptake and penetration of drugs into neuroblastoma.

scientific article published on 05 August 2013

Neuroblastoma targeting by c-myb-selective antisense oligonucleotides entrapped in anti-GD2 immunoliposome: immune cell-mediated anti-tumor activities.

scientific article

Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction

scientific article

Neuroblastoma-targeted nanocarriers improve drug delivery and penetration, delay tumor growth and abrogate metastatic diffusion

scientific article published on August 2015

New therapeutic strategies in neuroblastoma: combined targeting of a novel tyrosine kinase inhibitor and liposomal siRNAs against ALK.

scientific article published on 20 June 2015

Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings.

scientific article

Overcoming Biological Barriers in Neuroblastoma Therapy: The Vascular Targeting Approach with Liposomal Drug Nanocarriers

scientific article published on 01 February 2019

PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma

scientific article

Phosphatidylinositol turnover is not a general regulator of neuroblastoma cell differentiation: comparison between two differentiating agents, retinoic acid and gamma-interferon

scientific article published on 01 January 1989

Potent and sustained inhibition of HIF-1α and downstream genes by a polyethyleneglycol-SN38 conjugate, EZN-2208, results in anti-angiogenic effects

scientific article

Preclinical evaluation of the first intravenous small molecule MDM2 antagonist alone and in combination with temozolomide in neuroblastoma

scientific article published on 09 January 2019

Protein kinase C isoenzymes in human neuroblasts. Involvement of PKC epsilon in cell differentiation.

scientific article published on May 1993

Proteomic analysis of anti-angiogenic effects by a combined treatment with vinblastine and rapamycin in an endothelial cell line.

scientific article published in August 2006

Purification to homogeneity and biochemical characterization of two suppressor factors from human malignant T-cells

scientific article published on 01 January 1988

Quiescent hepatic stellate cells functionally contribute to the hepatic innate immune response via TLR3.

scientific article published on 8 January 2014

Retinoic acid inhibits phosphatidylinositol turnover only in RA-sensitive while not in RA-resistant human neuroblastoma cells

scientific article

Retinoic acid rapidly decreases phosphatidylinositol turnover during neuroblastoma cell differentiation

scientific article published on February 1990

Role of methylation in the control of DeltaNp73 expression in neuroblastoma

scientific article published on 01 March 2002

Selective therapeutic targeting of the anaplastic lymphoma kinase with liposomal siRNA induces apoptosis and inhibits angiogenesis in neuroblastoma

scientific article published on 9 August 2011

Spatiotemporal Regulation of Tumor Angiogenesis by Circulating Chromogranin A Cleavage and Neuropilin-1 Engagement

scientific article published on 22 February 2019

Spot overlapping in two-dimensional maps: a serious problem ignored for much too long

scientific article published in June 2005

Stimulation of receptor-coupled phospholipase A2 by interferon-gamma

scientific article published on September 1992

Study of proteomic changes associated with healthy and tumoral murine samples in neuroblastoma by principal component analysis and classification methods.

scientific article

Synergistic Differentiation-Promoting Activity of Interferon and Tumor Necrosis Factor- : Role of Receptor Regulation on Human Neuroblasts

scientific article published on 01 November 1994

Synergistic inhibition of human neuroblastoma-related angiogenesis by vinblastine and rapamycin

scientific article published on October 2005

Targeted delivery of oncogene-selective antisense oligonucleotides in neuroectodermal tumors: therapeutic implications

scientific article

Targeted delivery system for antisense oligonucleotides: a novel experimental strategy for neuroblastoma treatment.

scientific article

Targeted drug delivery and penetration into solid tumors

scientific article published on February 2011

Targeting Macrophages as a Potential Therapeutic Intervention: Impact on Inflammatory Diseases and Cancer

scientific article published in 2018

Targeting Vesicular LGALS3BP by an Antibody-Drug Conjugate as Novel Therapeutic Strategy for Neuroblastoma

scientific article published on 15 October 2020

Targeting liposomal chemotherapy via both tumor cell-specific and tumor vasculature-specific ligands potentiates therapeutic efficacy

scientific article published on October 2006

The Neuronal Pentraxin-2 Pathway Is an Unrecognized Target in Human Neuroblastoma, Which Also Offers Prognostic Value in Patients.

scientific article published on 20 August 2015

The combined therapeutic effects of bortezomib and fenretinide on neuroblastoma cells involve endoplasmic reticulum stress response

scientific article

The use of the orthotopic model to validate antivascular therapies for cancer ⬇️

scientific article published on January 1, 2011

Therapeutic targeting of TLR9 inhibits cell growth and induces apoptosis in neuroblastoma

scientific article published on 8 October 2010

Tumor regression and curability of preclinical neuroblastoma models by PEGylated SN38 (EZN-2208), a novel topoisomerase I inhibitor

scientific article published on 11 August 2010

Tumor vascular targeted liposomal-bortezomib minimizes side effects and increases therapeutic activity in human neuroblastoma

scientific article published on 29 May 2015

Tumor vascular targeting with tumor necrosis factor alpha and chemotherapeutic drugs

scientific article

Uncoordinate induction and differential regulation of HLA class-I and class-II expression by gamma-interferon in differentiating human neuroblastoma cells

scientific article published on November 1993

Updated clinical and biological information from the two-stage phase II study of imatinib mesylate in subjects with relapsed/refractory neuroblastoma

scientific article published on 30 July 2018

sTRAIL coupled to liposomes improves its pharmacokinetic profile and overcomes neuroblastoma tumour resistance in combination with Bortezomib

scientific article

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