List of works - Joel A Swanson

A Cdc42 activation cycle coordinated by PI 3-kinase during Fc receptor-mediated phagocytosis

scientific article

A growth factor signaling cascade confined to circular ruffles in macrophages.

scientific article

A phosphatidylinositol-3-kinase-dependent signal transition regulates ARF1 and ARF6 during Fcgamma receptor-mediated phagocytosis

scientific article

A prelysosomal compartment sequesters membrane-impermeant fluorescent dyes from the cytoplasmic matrix of J774 macrophages ⬇️

scientific article published on September 1, 1988

A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages

scientific article (publication date: December 1996)

Actin and phosphoinositide recruitment to fully formed Candida albicans phagosomes in mouse macrophages

scientific article

Adapter protein SH2-Bbeta stimulates actin-based motility of Listeria monocytogenes in a vasodilator-stimulated phosphoprotein (VASP)-dependent fashion

scientific article published on 23 April 2007

Amino acids suppress macropinocytosis and promote release of CSF1 receptor in macrophages

scientific article published on 21 February 2022

Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb

scientific article

CRISPR knockout screen implicates three genes in lysosome function

scientific article published on 03 July 2019

CXCL12-induced macropinocytosis modulates two distinct pathways to activate mTORC1 in macrophages

scientific article published on 17 October 2016

Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis.

scientific article published on 28 May 2004

Cellular dimensions affecting the nucleocytoplasmic volume ratio

scientific article published on November 1991

Coated vesicles in Dictyostelium discoideum

scientific article published on 01 May 1981

Coordination of Fc receptor signaling regulates cellular commitment to phagocytosis

scientific article

Coordination of the Rab5 cycle on macropinosomes

scientific article published on 9 October 2011

Cryptococcus neoformans-induced macrophage lysosome damage crucially contributes to fungal virulence

scientific article

Cytolysin-dependent delay of vacuole maturation in macrophages infected with Listeria monocytogenes.

scientific article

Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

scientific article published on 22 May 2011

Determination of the physical environment within the Chlamydia trachomatis inclusion using ion-selective ratiometric probes

scientific article published on May 2002

Different fates of phagocytosed particles after delivery into macrophage lysosomes.

scientific article

Differential signaling during macropinocytosis in response to M-CSF and PMA in macrophages

scientific article published on 29 January 2015

Dorsal ruffles enhance activation of Akt by growth factors

scientific article published on 16 November 2018

Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities

scientific article

Dynamics of cytoskeletal proteins during Fcgamma receptor-mediated phagocytosis in macrophages

scientific article

Early Bacillus anthracis-macrophage interactions: intracellular survival survival and escape

scientific article published on 01 December 2000

Effect of alterations in the size of the vacuolar compartment on pinocytosis in J774.2 macrophages

scientific article published in August 1986

Effects of macromolecular crowding on nuclear size

scientific article published in May 1995

Fc-receptor-mediated phagocytosis occurs in macrophages without an increase in average [Ca++]i.

scientific article

Growth factor signaling to mTORC1 by amino acid-laden macropinosomes

scientific article

Inducible renitence limits Listeria monocytogenes escape from vacuoles in macrophages.

scientific article

Listeria monocytogenes exploits cystic fibrosis transmembrane conductance regulator (CFTR) to escape the phagosome.

scientific article

Live cell fluorescence microscopy to study microbial pathogenesis

scientific article

Local and spatially coordinated movements in Dictyostelium discoideum amoebae during chemotaxis

scientific article published on 01 February 1982

Localization of protein kinase C epsilon to macrophage vacuoles perforated by Listeria monocytogenes cytolysin

scientific article

Macropinocytosis

scientific article published on 01 November 1995

Macropinocytosis drives T cell growth by sustaining the activation of mTORC1

scientific article published on 10 January 2020

Macropinocytosis, mTORC1 and cellular growth control

scientific article published on 8 November 2017

Macropinosome maturation and fusion with tubular lysosomes in macrophages.

scientific article

Membrane perforations inhibit lysosome fusion by altering pH and calcium in Listeria monocytogenes vacuoles

scientific article published on May 2006

Microtubules can modulate pseudopod activity from a distance inside macrophages

scientific article published on 01 January 1996

Molecular size-fractionation during endocytosis in macrophages.

scientific article

N-way FRET microscopy of multiple protein-protein interactions in live cells

scientific article (publication date: 2013)

Nuclear reassembly excludes large macromolecules

scientific article published in October 1987

Phagocytosis by zippers and triggers

scientific article published on 01 March 1995

Phosphoinositide-3-kinase-independent contractile activities associated with Fcgamma-receptor-mediated phagocytosis and macropinocytosis in macrophages

scientific article published in January 2003

Phosphoinositides and engulfment

scientific article

Protection from anthrax toxin-mediated killing of macrophages by the combined effects of furin inhibitors and chloroquine.

scientific article

Proteolytic activation of receptor-bound anthrax protective antigen on macrophages promotes its internalization.

scientific article

Pulse-shaping based two-photon FRET stoichiometry

scientific article

Pulse-shaping multiphoton FRET microscopy.

scientific article

Pure thoughts with impure proteins: permeabilized cell models of organelle motility

scientific article published on November 1993

Radial extension of macrophage tubular lysosomes supported by kinesin

scientific article published on August 1990

Ratiometric and fluorescence-lifetime-based biosensors incorporating cytochrome c' and the detection of extra- and intracellular macrophage nitric oxide

scientific article published on 01 May 1999

Renitence vacuoles facilitate protection against phagolysosomal damage in activated macrophages

scientific article published on 27 December 2017

Reverse Engineering the Intracellular Self-Assembly of a Functional Mechanopharmaceutical Device

scientific article published on 13 February 2018

Ruffles limit diffusion in the plasma membrane during macropinosome formation ⬇️

scientific article published on December 1, 2011

Salmonella stimulate macrophage macropinocytosis and persist within spacious phagosomes.

scientific article

Sequential signaling in plasma-membrane domains during macropinosome formation in macrophages

scientific article

Shaping cups into phagosomes and macropinosomes

scientific article

Technical advance: Caspase-1 activation and IL-1β release correlate with the degree of lysosome damage, as illustrated by a novel imaging method to quantify phagolysosome damage.

scientific article

The Listeria monocytogenes hemolysin has an acidic pH optimum to compartmentalize activity and prevent damage to infected host cells

scientific article

The coordination of signaling during Fc receptor-mediated phagocytosis

scientific article

The efficiency of antigen delivery from macrophage phagosomes into cytoplasm for MHC class I-restricted antigen presentation

scientific article published on April 1997

The endocytic activity of dendritic cells.

scientific article published on August 1995

The extraordinary phagosome

scientific article published in Nature

The noodle defense

scientific article published on December 2013

The role of the activated macrophage in clearing Listeria monocytogenes infection

scientific article

The uniformity of phagosome maturation in macrophages

scientific article

Three-dimensional FRET reconstruction microscopy for analysis of dynamic molecular interactions in live cells

scientific article published on 13 March 2008

Transcellular delivery of vesicular SOCS proteins from macrophages to epithelial cells blunts inflammatory signaling

scientific article published on 6 April 2015

Transient increase in cyclic AMP localized to macrophage phagosomes

scientific article

Two-photon imaging of multiple fluorescent proteins by phase-shaping and linear unmixing with a single broadband laser.

scientific article

Under the microscope: single molecule symposium at the University of Michigan, 2006

scientific article published on 01 February 2007

pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes.

scientific article

List of works by Joel A Swanson

A Cdc42 activation cycle coordinated by PI 3-kinase during Fc receptor-mediated phagocytosis

A growth factor signaling cascade confined to circular ruffles in macrophages.

A phosphatidylinositol-3-kinase-dependent signal transition regulates ARF1 and ARF6 during Fcgamma receptor-mediated phagocytosis

A prelysosomal compartment sequesters membrane-impermeant fluorescent dyes from the cytoplasmic matrix of J774 macrophages ⬇️

A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages

Actin and phosphoinositide recruitment to fully formed Candida albicans phagosomes in mouse macrophages

Adapter protein SH2-Bbeta stimulates actin-based motility of Listeria monocytogenes in a vasodilator-stimulated phosphoprotein (VASP)-dependent fashion

Amino acids suppress macropinocytosis and promote release of CSF1 receptor in macrophages

Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb

CRISPR knockout screen implicates three genes in lysosome function

CXCL12-induced macropinocytosis modulates two distinct pathways to activate mTORC1 in macrophages

Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis.

Cellular dimensions affecting the nucleocytoplasmic volume ratio

Coated vesicles in Dictyostelium discoideum

Coordination of Fc receptor signaling regulates cellular commitment to phagocytosis

Coordination of the Rab5 cycle on macropinosomes

Cryptococcus neoformans-induced macrophage lysosome damage crucially contributes to fungal virulence

Cytolysin-dependent delay of vacuole maturation in macrophages infected with Listeria monocytogenes.

Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

Determination of the physical environment within the Chlamydia trachomatis inclusion using ion-selective ratiometric probes

Different fates of phagocytosed particles after delivery into macrophage lysosomes.

Differential signaling during macropinocytosis in response to M-CSF and PMA in macrophages

Dorsal ruffles enhance activation of Akt by growth factors

Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities

Dynamics of cytoskeletal proteins during Fcgamma receptor-mediated phagocytosis in macrophages

Early Bacillus anthracis-macrophage interactions: intracellular survival survival and escape

Effect of alterations in the size of the vacuolar compartment on pinocytosis in J774.2 macrophages

Effects of macromolecular crowding on nuclear size

Fc-receptor-mediated phagocytosis occurs in macrophages without an increase in average [Ca++]i.

Growth factor signaling to mTORC1 by amino acid-laden macropinosomes

Inducible renitence limits Listeria monocytogenes escape from vacuoles in macrophages.

Listeria monocytogenes exploits cystic fibrosis transmembrane conductance regulator (CFTR) to escape the phagosome.

Live cell fluorescence microscopy to study microbial pathogenesis

Local and spatially coordinated movements in Dictyostelium discoideum amoebae during chemotaxis

Localization of protein kinase C epsilon to macrophage vacuoles perforated by Listeria monocytogenes cytolysin

Macropinocytosis

Macropinocytosis drives T cell growth by sustaining the activation of mTORC1

Macropinocytosis, mTORC1 and cellular growth control

Macropinosome maturation and fusion with tubular lysosomes in macrophages.

Membrane perforations inhibit lysosome fusion by altering pH and calcium in Listeria monocytogenes vacuoles

Microtubules can modulate pseudopod activity from a distance inside macrophages

Molecular size-fractionation during endocytosis in macrophages.

N-way FRET microscopy of multiple protein-protein interactions in live cells

Nuclear reassembly excludes large macromolecules

Phagocytosis by zippers and triggers

Phosphoinositide-3-kinase-independent contractile activities associated with Fcgamma-receptor-mediated phagocytosis and macropinocytosis in macrophages

Phosphoinositides and engulfment

Protection from anthrax toxin-mediated killing of macrophages by the combined effects of furin inhibitors and chloroquine.

Proteolytic activation of receptor-bound anthrax protective antigen on macrophages promotes its internalization.

Pulse-shaping based two-photon FRET stoichiometry

Pulse-shaping multiphoton FRET microscopy.

Pure thoughts with impure proteins: permeabilized cell models of organelle motility

Radial extension of macrophage tubular lysosomes supported by kinesin

Ratiometric and fluorescence-lifetime-based biosensors incorporating cytochrome c' and the detection of extra- and intracellular macrophage nitric oxide

Renitence vacuoles facilitate protection against phagolysosomal damage in activated macrophages

Reverse Engineering the Intracellular Self-Assembly of a Functional Mechanopharmaceutical Device

Ruffles limit diffusion in the plasma membrane during macropinosome formation ⬇️

Salmonella stimulate macrophage macropinocytosis and persist within spacious phagosomes.

Sequential signaling in plasma-membrane domains during macropinosome formation in macrophages

Shaping cups into phagosomes and macropinosomes

Technical advance: Caspase-1 activation and IL-1β release correlate with the degree of lysosome damage, as illustrated by a novel imaging method to quantify phagolysosome damage.

The Listeria monocytogenes hemolysin has an acidic pH optimum to compartmentalize activity and prevent damage to infected host cells

The coordination of signaling during Fc receptor-mediated phagocytosis

The efficiency of antigen delivery from macrophage phagosomes into cytoplasm for MHC class I-restricted antigen presentation

The endocytic activity of dendritic cells.

The extraordinary phagosome

The noodle defense

The role of the activated macrophage in clearing Listeria monocytogenes infection

The uniformity of phagosome maturation in macrophages

Three-dimensional FRET reconstruction microscopy for analysis of dynamic molecular interactions in live cells

Transcellular delivery of vesicular SOCS proteins from macrophages to epithelial cells blunts inflammatory signaling

Transient increase in cyclic AMP localized to macrophage phagosomes

Two-photon imaging of multiple fluorescent proteins by phase-shaping and linear unmixing with a single broadband laser.

Under the microscope: single molecule symposium at the University of Michigan, 2006

pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes.