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List of works by Lena Eliasson

35th Annual Meeting of the European Association for the Study of Diabetes

article

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

article

A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.

scientific article

A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis

scientific article published on 21 November 2008

A circular RNA generated from an intron of the insulin gene controls insulin secretion

scientific article published on 05 November 2020

A dominant mutation in Snap25 causes impaired vesicle trafficking, sensorimotor gating, and ataxia in the blind-drunk mouse.

scientific article

A pancreatic islet-specific microRNA regulates insulin secretion

scientific article

Activation of Ca(2+)-dependent K(+) channels contributes to rhythmic firing of action potentials in mouse pancreatic beta cells

scientific article

Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.

scientific article

Adenovirus-mediated silencing of synaptotagmin 9 inhibits Ca2+-dependent insulin secretion in islets

scientific journal article

An 'alpha-beta' of pancreatic islet microribonucleotides

scientific article published on 22 January 2017

Antibody inhibition of synaptosomal protein of 25 kDa (SNAP-25) and syntaxin 1 reduces rapid exocytosis in insulin-secreting cells

scientific article published on 01 June 2006

Argonaute2 mediates compensatory expansion of the pancreatic β cell

scientific article

Beta-cell PDE3B regulates Ca2+-stimulated exocytosis of insulin

scientific article

Beta-cell specific deletion of Dicer1 leads to defective insulin secretion and diabetes mellitus.

scientific article

Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes

scientific article

Bone morphogenetic protein 4 inhibits insulin secretion from rodent beta cells through regulation of calbindin1 expression and reduced voltage-dependent calcium currents.

scientific article published on 02 April 2015

CD46 Activation Regulates miR-150-Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4+ T Cells

scientific article published on 8 January 2016

CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells

scientific article

CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells

scientific article

Ca(2+)- and GTP-dependent exocytosis in mouse pancreatic beta-cells involves both common and distinct steps

scientific article published in October 1996

CaM kinase II-dependent mobilization of secretory granules underlies acetylcholine-induced stimulation of exocytosis in mouse pancreatic B-cells

scientific article published in August 1999

CaV1.2 rather than CaV1.3 is coupled to glucose-stimulated insulin secretion in INS-1 832/13 cells

scientific article

Calcium current inactivation rather than pool depletion explains reduced exocytotic rate with prolonged stimulation in insulin-secreting INS-1 832/13 cells

scientific article

Calcium increases endocytotic vesicle size and accelerates membrane fission in insulin-secreting INS-1 cells.

scientific article published on 29 November 2005

Capacitance measurements of exocytosis in mouse pancreatic alpha-, beta- and delta-cells within intact islets of Langerhans

scientific article published on 13 February 2004

Cell coupling in mouse pancreatic beta-cells measured in intact islets of Langerhans

scientific article published in October 2008

Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells

scientific article published on January 1995

Confluence does not affect the expression of miR-375 and its direct targets in rat and human insulin-secreting cell lines.

scientific article published on 28 June 2017

Cooling inhibits exocytosis in single mouse pancreatic B-cells by suppression of granule mobilization

scientific article published on 01 July 1996

Defective exocytosis and processing of insulin in a cystic fibrosis mouse model

scientific article published on 01 February 2019

Differences in islet-enriched miRNAs in healthy and glucose intolerant human subjects

scientific article published on 19 November 2010

Differential glucose-regulation of microRNAs in pancreatic islets of non-obese type 2 diabetes model Goto-Kakizaki rat

scientific article

Dual Effect of Rosuvastatin on Glucose Homeostasis Through Improved Insulin Sensitivity and Reduced Insulin Secretion.

scientific article

Dynamic magnetic fields remote-control apoptosis via nanoparticle rotation

scientific article

Electrophysiology of pancreatic β-cells in intact mouse islets of Langerhans

scientific article published on 06 July 2011

Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell

scientific article

Endocytosis of secretory granules in mouse pancreatic beta-cells evoked by transient elevation of cytosolic calcium

scientific article published on 01 June 1996

Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes.

scientific article

Enhancement of glucagon secretion in mouse and human pancreatic alpha cells by protein kinase C (PKC) involves intracellular trafficking of PKCalpha and PKCdelta

scientific article published on 18 December 2009

Erythropoietin and TRPV1 together in new formation

scientific article published in August 2016

Exocytosis elicited by action potentials and voltage-clamp calcium currents in individual mouse pancreatic B-cells

scientific article published on 01 December 1993

Exposure to bisphenol A, but not phthalates, increases spontaneous diabetes type 1 development in NOD mice

scientific article published on 28 February 2015

Exposure to maternal obesity programs sex differences in pancreatic islets of the offspring in mice

scientific article published on 26 November 2019

Fast insulin secretion reflects exocytosis of docked granules in mouse pancreatic B-cells

scientific article

Fast surface acoustic wave-matrix-assisted laser desorption ionization mass spectrometry of cell response from islets of Langerhans

scientific article

Functional implications of long non-coding RNAs in the pancreatic islets of Langerhans.

scientific article

GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosis

scientific article published in June 2010

Gastrin and the neuropeptide PACAP evoke secretion from rat stomach histamine-containing (ECL) cells by stimulating influx of Ca2+ through different Ca2+ channels

scientific article

Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion

scientific article

Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism

scientific article

Glucagon stimulates exocytosis in mouse and rat pancreatic alpha-cells by binding to glucagon receptors

scientific journal article

Glucocorticoid induces human beta cell dysfunction by involving riborepressor GAS5 LincRNA

scientific article published on 27 December 2019

Glucolipotoxicity Alters Insulin Secretion via Epigenetic Changes in Human Islets

scientific article published on 16 August 2019

Glucose-dependent docking and SNARE protein-mediated exocytosis in mouse pancreatic alpha-cell

scientific article published on 04 June 2011

HDAC7 is overexpressed in human diabetic islets and impairs insulin secretion in rat islets and clonal beta cells

scientific article published on 29 October 2016

Human pancreatic islet miRNA-mRNA networks of altered miRNAs due to glycemic status

scientific article published on 26 February 2022

Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes

scientific article published on 18 August 2017

Impaired insulin exocytosis in neural cell adhesion molecule-/- mice due to defective reorganization of the submembrane F-actin network

scientific article published on 12 February 2009

In Vivo Silencing of MicroRNA-132 Reduces Blood Glucose and Improves Insulin Secretion

scientific article published on 23 January 2019

Inhibition of phosphodiesterase 3, 4, and 5 induces endolymphatic hydrops in mouse inner ear, as evaluated with repeated 9.4T MRI.

scientific article

Insulin secretion is highly sensitive to desorption of plasma membrane cholesterol.

scientific article published on 19 September 2008

Integrator of Stress Responses Calmodulin Binding Transcription Activator 1 (Camta1) Regulates miR-212/miR-132 Expression and Insulin Secretion

scientific article published on 8 July 2016

Ion channels, electrical activity and insulin secretion.

scientific article published on March 1994

Islet microRNAs in health and type-2 diabetes

article

Lack of cholesterol mobilization in islets of hormone-sensitive lipase deficient mice impairs insulin secretion

scientific article

Large dense-core vesicle exocytosis in pancreatic $beta;-cells monitored by capacitance measurements

scientific article published on 01 August 2004

Lessons from basic pancreatic beta cell research in type-2 diabetes and vascular complications

scientific article published on 23 January 2017

Long-term exposure of mouse pancreatic islets to oleate or palmitate results in reduced glucose-induced somatostatin and oversecretion of glucagon

scientific article published on 12 July 2008

Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane

scientific article

Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes

scientific article published on 10 June 2014

MC1568 improves insulin secretion in islets from type 2 diabetes patients and rescues β-cell dysfunction caused by Hdac7 upregulation

scientific article published on 07 August 2018

Mathematical modeling and statistical analysis of calcium-regulated insulin granule exocytosis in β-cells from mice and humans

scientific article published on 04 August 2011

Melatonin heals the gut

scientific article published on 06 September 2014

MiR-335 overexpression impairs insulin secretion through defective priming of insulin vesicles.

scientific article

Micro(RNA) Management and Mismanagement of the Islet

scientific article published on 16 October 2019

MicroRNA Networks in Pancreatic Islet Cells: Normal Function and Type 2 Diabetes

scientific article published on 01 May 2020

MicroRNA-7a regulates pancreatic β cell function

scientific article

MicroRNAs in islet hormone secretion

scientific article published on 01 September 2018

Mitochondrial transcription factor B2 is essential for mitochondrial and cellular function in pancreatic β-cells

scientific article

Modulation of microRNA-375 expression alters voltage-gated Na(+) channel properties and exocytosis in insulin-secreting cells

scientific article published on 15 February 2015

Multivesicular exocytosis in rat pancreatic beta cells.

scientific article

N1-methylnicotinamide is a signalling molecule produced in skeletal muscle coordinating energy metabolism.

scientific article published on 14 February 2018

Neuron-enriched RNA-binding Proteins Regulate Pancreatic Beta Cell Function and Survival.

scientific article published on 11 January 2017

New drug for treatment of insulin-resistant complication?

scientific article published in March 2013

Nova1 is a master regulator of alternative splicing in pancreatic beta cells.

scientific article

Novel aspects of the molecular mechanisms controlling insulin secretion

scientific article published on 29 May 2008

Osteopontin Affects Insulin Vesicle Localization and Ca2+ Homeostasis in Pancreatic Beta Cells from Female Mice

scientific article

Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes

scientific article

PIWI-interacting RNAs as novel regulators of pancreatic beta cell function

scientific article published on 16 July 2017

PKC-Dependent Stimulation of Exocytosis by Sulfonylureas in Pancreatic beta Cells

scientific article published in Science

Pancreatic α-cells - The unsung heroes in islet function

scientific article published on 23 January 2020

Partners for life

scientific article published on 18 May 2016

Pleiotropic effects of GIP on islet function involve osteopontin

scientific article

Priming of insulin granules for exocytosis by granular Cl(-) uptake and acidification

scientific article published in June 2001

Progesterone metabolite influence feeding behaviour

scientific article published on 14 June 2013

Protein kinase A-dependent and -independent stimulation of exocytosis by cAMP in mouse pancreatic B-cells

scientific article published on 01 July 1997

R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion

scientific journal article

Rapid ATP-Dependent Priming of Secretory Granules Precedes Ca2+-Induced Exocytosis in Mouse Pancreatic B-Cells

scientific article published on 01 September 1997

Reduced blood glucose through thyroid hormone degradation product

scientific article

Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes

scientific article

Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes.

scientific article published on 23 August 2012

Regulated exocytosis and kiss-and-run of synaptic-like microvesicles in INS-1 and primary rat beta-cells.

scientific article published on March 2005

Regulated exocytosis of GABA-containing synaptic-like microvesicles in pancreatic beta-cells.

scientific article

Regulation of Pancreatic Beta Cell Stimulus-Secretion Coupling by microRNAs.

scientific article

Role of non-coding RNAs in pancreatic beta-cell development and physiology

scientific article published on 15 April 2014

Rosuvastatin Treatment Affects Both Basal and Glucose-Induced Insulin Secretion in INS-1 832/13 Cells

scientific article

SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells

scientific article

Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes

scientific article

Secretory and electrophysiological characteristics of insulin cells from gastrectomized mice: Evidence for the existence of insulinotropic agents in the stomach

scientific article published on 15 November 2006

Selectively Bred Diabetes Models: GK Rats, NSY Mice, and ON Mice

scientific article published on 01 January 2020

Serotonin (5-HT) receptor 2b activation augments glucose-stimulated insulin secretion in human and mouse islets of Langerhans

scientific article published on 6 January 2016

Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets

scientific article

She is in Science to Stay!

scientific article published on 6 February 2018

Somatostatin secretion by Na+-dependent Ca2+-induced Ca2+ release in pancreatic delta-cells

scientific article published on 20 January 2020

Somatostatin, misoprostol and galanin inhibit gastrin- and PACAP-stimulated secretion of histamine and pancreastatin from ECL cells by blocking specific Ca2+ channels

scientific article published in August 2005

Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes

scientific article

Suppression of sulfonylurea- and glucose-induced insulin secretion in vitro and in vivo in mice lacking the chloride transport protein ClC-3.

scientific article published in October 2009

Synapsins I and II are not required for insulin secretion from mouse pancreatic β-cells

scientific article

TIGER: The gene expression regulatory variation landscape of human pancreatic islets

scientific article published on 01 October 2021

The Cell Physiology of Biphasic Insulin Secretion.

scientific article published in April 2000

The TCF7L2-dependent high-voltage activated calcium channel subunit α2δ-1 controls calcium signaling in rodent pancreatic beta-cells

scientific article published on 02 December 2019

The calcium channel subunit gamma-4 is regulated by MafA and necessary for pancreatic beta-cell specification

scientific article published on 15 March 2019

The exocytotic machinery

scientific article published on March 2014

The first gamma-carboxyglutamic acid-containing contryphan. A selective L-type calcium ion channel blocker isolated from the venom of Conus marmoreus

scientific article

The small RNA miR-375 - a pancreatic islet abundant miRNA with multiple roles in endocrine beta cell function

scientific article published on 27 February 2017

Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells

scientific article published in September 2000

Transcriptional regulation of the miR-212/miR-132 cluster in insulin-secreting β-cells by cAMP-regulated transcriptional co-activator 1 and salt-inducible kinases

scientific article published on 12 January 2016

Truncation of SNAP-25 reduces the stimulatory action of cAMP on rapid exocytosis in insulin-secreting cells

scientific article published on 09 June 2009

Whole-Genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis

scientific article

Why treatment fails in type 2 diabetes

scientific article

miR-184 Regulates Pancreatic β-Cell Function According to Glucose Metabolism

scientific article

miR-483-5p associates with obesity and insulin resistance and independently associates with new onset diabetes mellitus and cardiovascular disease

scientific article published in PLoS ONE

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