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List of works by Dennis W. Metzger

A detrimental effect of interleukin-10 on protective pulmonary humoral immunity during primary influenza A virus infection

scientific article published on 3 March 2010

A monoclonal antibody (SJ-9A4) to P24 present on common alls, neuroblastomas and platelets - I. Characterization and development of a unique radioimmunometric assay

scientific article published on 01 January 1983

A pivotal role for interferon-gamma in protection against group A streptococcal skin infection

scientific article published on 01 February 2000

Adaptation of Francisella tularensis to the mammalian environment is governed by cues which can be mimicked in vitro

scientific article

Alarmin function of galectin-9 in murine respiratory tularemia

scientific article published on 21 April 2015

An improved vaccine for prevention of respiratory tularemia caused by Francisella tularensis SchuS4 strain

scientific article published on 08 August 2008

Analysis of murine genetic predisposition to pneumococcal infection reveals a critical role of alveolar macrophages in maintaining the sterility of the lower respiratory tract.

scientific article

Antibody response of murine B1 cells to hen eggwhite lysozyme

scientific article published on 01 March 1995

Asthma increases susceptibility to heterologous but not homologous secondary influenza

scientific article

Azithromycin modulates murine immune responses to pneumococcal conjugate vaccine and inhibits nasal clearance of bacteria

scientific article published on 13 October 2004

Characterization of a monoclonal antibody reactive with rabbit T lymphocytes and neutrophils

scientific article published in May 1984

Contribution of citrulline ureidase to Francisella tularensis strain Schu S4 pathogenesis

scientific article published on 05 June 2009

Cyclic di-AMP impairs potassium uptake mediated by a cyclic di-AMP binding protein in Streptococcus pneumoniae.

scientific article

Cyclic pressure affects osteoblast functions pertinent to osteogenesis

scientific article published in September 2003

Design of a protective single-dose intranasal nanoparticle-based vaccine platform for respiratory infectious diseases

scientific article

Detection of cyclic di-AMP using a competitive ELISA with a unique pneumococcal cyclic di-AMP binding protein

scientific article

Direct binding of IL-12 to human and murine B lymphocytes

scientific article published on 01 December 1996

Distinct functions of antigenic sites of the HN glycoprotein of Sendai virus

scientific article published in May 1987

Does Type I Interferon Limit Protective Neutrophil Responses during Pulmonary Francisella Tularensis Infection?

scientific article published on 23 July 2014

Early activation of NK cells after lung infection with the intracellular bacterium, Francisella tularensis LVS.

scientific article published in November 2004

Effects of cyclic pressure on bone marrow cell cultures

scientific article

Emerging roles of T helper subsets in the pathogenesis of asthma

scientific article published on January 2010

Enhancement of humoral immunity by interleukin-12

scientific article published on 01 October 1996

Exogenous interleukin-12 protects against lethal infection with coxsackievirus B4.

scientific article

Expression of suppressor of cytokine signaling 1 (SOCS1) impairs viral clearance and exacerbates lung injury during influenza infection.

scientific article published on 11 December 2014

Frequency- and duration-dependent effects of cyclic pressure on select bone cell functions

scientific article published on 01 December 2001

Galectin-3 functions as an alarmin: pathogenic role for sepsis development in murine respiratory tularemia

scientific article

Generation and characterization of an attenuated mutant in a response regulator gene of Francisella tularensis live vaccine strain (LVS).

scientific article

Group A streptococcal isolate 64/14 expresses surface plasmin-binding structures in addition to Plr

scientific article published on 01 September 1997

Heating of immunoglobulins for immunoblot analysis destroys variable region antigenicity

scientific article published on 01 November 1986

Host-pathogen interactions and immune evasion strategies in Francisella tularensis pathogenicity

scientific article

Humoral and cell-mediated immunity to the intracellular pathogen Francisella tularensis.

scientific article published on October 2008

IL-12 as an adjuvant for the enhancement of protective humoral immunity

scientific article published in May 2009

IL-12 can alleviate Th17-mediated allergic lung inflammation through induction of pulmonary IL-10 expression

scientific article published on 17 March 2010

IL-12 is a potent neonatal vaccine adjuvant

scientific article published on 01 January 1999

IL-12-mediated increases in protection elicited by pneumococcal and meningococcal conjugate vaccines

scientific article published on 01 February 2001

Identification of Francisella tularensis live vaccine strain CuZn superoxide dismutase as critical for resistance to extracellularly generated reactive oxygen species

scientific article published on 14 August 2009

Identification of Francisella tularensis outer membrane protein A (FopA) as a protective antigen for tularemia.

scientific article

Identification of a live attenuated vaccine candidate for tularemia prophylaxis

scientific article

Identification of a novel Francisella tularensis factor required for intramacrophage survival and subversion of innate immune response

scientific article

IgA is important for clearance and critical for protection from rotavirus infection ⬇️

scientific article published on June 27, 2012

Immune dysfunction and bacterial coinfections following influenza

scientific article published on September 2013

Immune response to small intestinal submucosa (surgisis) implant in humans: preliminary observations

scientific article published in July 2007

In vivo activation of quiescent B cells by anti-immunoglobulin. II. Production of lysozyme-specific monoclonal antibodies of desired isotype

scientific article published on 01 February 1988

Inactivated Francisella tularensis live vaccine strain protects against respiratory tularemia by intranasal vaccination in an immunoglobulin A-dependent fashion.

scientific article published on 12 February 2007

Increased susceptibility of IgA-deficient mice to pulmonary Francisella tularensis live vaccine strain infection

scientific article published on 08 July 2013

Influenza infection suppresses NADPH oxidase-dependent phagocytic bacterial clearance and enhances susceptibility to secondary methicillin-resistant Staphylococcus aureus infection

scientific article published on 21 February 2014

Inhibition of murine B1 lymphocytes by interleukin-12

scientific article published on 01 January 1996

Inhibition of pulmonary antibacterial defense by interferon-gamma during recovery from influenza infection

scientific article published on 27 April 2008

Interleukin-12 acts as an adjuvant for humoral immunity through interferon-gamma-dependent and -independent mechanisms

scientific article published on 01 August 1997

Interleukin-12 as an adjuvant for induction of protective antibody responses.

scientific article published on 22 July 2010

Interleukin-12 enhances clinical experimental autoimmune myasthenia gravis in susceptible but not resistant mice

scientific article published on 01 July 2000

Interleukin-12 promotes gamma interferon-dependent neutrophil recruitment in the lung and improves protection against respiratory Streptococcus pneumoniae infection

scientific article published on 8 January 2007

Intranasal Administration of an Inactivated Yersinia pestis Vaccine with Interleukin-12 Generates Protective Immunity against Pneumonic Plague ⬇️

scientific article published on August 31, 2011

Intranasal interleukin-12 is a powerful adjuvant for protective mucosal immunity

scientific article published on 01 October 1999

Intranasal interleukin-12 treatment for protection against respiratory infection with the Francisella tularensis live vaccine strain.

scientific article

Intranasal vaccination of neonatal mice with polysaccharide conjugate vaccine for protection against pneumococcal otitis media

scientific article published on 08 May 2006

Intranasal vaccination using interleukin-12 and cholera toxin subunit B as adjuvants to enhance mucosal and systemic immunity to human immunodeficiency virus type 1 glycoproteins.

scientific article

Intranasal vaccination with pneumococcal surface protein A and interleukin-12 augments antibody-mediated opsonization and protective immunity against Streptococcus pneumoniae infection.

scientific article

Localization of frog virus 3 proteins using monoclonal antibodies

scientific article published in August 1984

Modulation of mucosal and systemic immunity by intranasal interleukin 12 delivery

scientific article published on 01 January 1999

Mucosal immunopathogenesis of Francisella tularensis.

scientific article published on 29 March 2007

Natural anti-galactose alpha1,3 galactose antibodies delay, but do not prevent the acceptance of extracellular matrix xenografts

scientific article published in June 2002

Novel current-conducting composite substrates for exposing osteoblasts to alternating current stimulation

scientific article published on 01 March 2002

Prospects for use of interleukin-12 as a mucosal adjuvant for vaccination of humans to protect against respiratory pneumococcal infection.

scientific article published on 03 July 2008

Rational design of pathogen-mimicking amphiphilic materials as nanoadjuvants.

scientific article published on 16 December 2011

Seasonal FluMist vaccination induces cross-reactive T cell immunity against H1N1 (2009) influenza and secondary bacterial infections

scientific article

Single-chain Fv of anti-idiotype 11-1G10 antibody interacts with antibody NC41 single-chain Fv with a higher affinity than the affinity for the interaction of the parent Fab fragments

article

Superoxide dismutase B gene (sodB)-deficient mutants of Francisella tularensis demonstrate hypersensitivity to oxidative stress and attenuated virulence

scientific article

The Th2-restricted immune response to xenogeneic small intestinal submucosa does not influence systemic protective immunity to viral and bacterial pathogens

scientific article published in February 2002

The effects of IL12 on B-cell subset function.

scientific article published on September 1995

The rabbit B cell antigen receptor is non-covalently associated with unique heteromeric protein complexes: possible insights into the membrane IgM/IgD coexpression paradox

scientific article published in July 1995

The vitamin B₆ biosynthesis pathway in Streptococcus pneumoniae is controlled by pyridoxal 5'-phosphate and the transcription factor PdxR and has an impact on ear infection.

scientific article published on 8 March 2013

Two DHH subfamily 1 proteins in Streptococcus pneumoniae possess cyclic di-AMP phosphodiesterase activity and affect bacterial growth and virulence

scientific article published on 06 September 2013

Type I IFN signaling constrains IL-17A/F secretion by gammadelta T cells during bacterial infections

scientific article

Use and misuse of statistical significance in survival analyses

scientific article published on 4 March 2014

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