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List of works by Tracy Murray-Stewart

(R,R)-1,12-Dimethylspermine can mitigate abnormal spermidine accumulation in Snyder-Robinson syndrome

scientific article published on 29 January 2020

A Phase Ib multicenter, dose-escalation study of the polyamine analogue PG-11047 in combination with gemcitabine, docetaxel, bevacizumab, erlotinib, cisplatin, 5-fluorouracil, or sunitinib in patients with advanced solid tumors or lymphoma

scientific article published on 19 November 2020

A phase I dose-escalation study of the polyamine analog PG-11047 in patients with advanced solid tumors

scientific article published on 23 May 2020

A simple assay for mammalian spermine oxidase: a polyamine catabolic enzyme implicated in drug response and disease

scientific article published on January 2011

Activation of endoplasmic reticulum stress response by enhanced polyamine catabolism is important in the mediation of cisplatin-induced acute kidney injury.

scientific article published on 8 September 2017

Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection.

scientific article

Autophagy induction by exogenous polyamines is an artifact of bovine serum amine oxidase activity in culture serum

scientific article published on 19 May 2020

Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano11047

scientific article

Correction: Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano11047.

scientific article published on 16 May 2017

Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies

scientific article published in PLoS ONE

Dual inhibitors of LSD1 and spermine oxidase

scientific article published on 08 February 2019

Editorial to the Special Issue on “Polyamine Metabolism in Health and Disease: Potential for Polyamine-Targeted Therapies and Prevention”

scientific article published in 2023

Epigenetic silencing of miR-124 prevents spermine oxidase regulation: implications for Helicobacter pylori-induced gastric cancer.

scientific article published on 04 April 2016

Histone deacetylase inhibition overcomes drug resistance through a miRNA-dependent mechanism.

scientific article published on 13 August 2013

Increased Helicobacter pylori-associated gastric cancer risk in the Andean region of Colombia is mediated by spermine oxidase.

scientific article

Induction of human spermine oxidase SMO(PAOh1) is regulated at the levels of new mRNA synthesis, mRNA stabilization and newly synthesized protein

scientific article published on March 2005

Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy

scientific article published on 05 March 2020

Inhibitors of DNA Methylation, Histone Deacetylation, and Histone Demethylation: A Perfect Combination for Cancer Therapy

scientific article published on 2 March 2016

Nuclear localization of human spermine oxidase isoforms - possible implications in drug response and disease etiology

scientific article

Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes ⬇️

scientific article published on March 15, 2012

Polyamine Homeostasis in Snyder-Robinson Syndrome

Polyamine catabolism and oxidative damage

scientific article published in Journal of Biological Chemistry

Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis -induced colon tumorigenesis ⬇️

scientific article published on August 29, 2011

Polyamine catabolism in carcinogenesis: potential targets for chemotherapy and chemoprevention

scientific article published on 15 June 2013

Polyamine catabolism is enhanced after traumatic brain injury.

scientific article

Polyamine metabolism and cancer: treatments, challenges and opportunities

article

Polyamine-Based Nanostructures Share Polyamine Transport Mechanisms with Native Polyamines and Their Analogues: Significance for Polyamine-Targeted Therapy

scientific article published in 2022

Polyamine-based small molecule epigenetic modulators.

scientific article published on 26 November 2011

Polyamines in cancer: integrating organismal metabolism and antitumour immunity

scientific article published in 2022

Polyaminohydroxamic acids and polyaminobenzamides as isoform selective histone deacetylase inhibitors

scientific article

Properties of purified recombinant human polyamine oxidase, PAOh1/SMO

scientific journal article

Proximal tubule epithelial cell specific ablation of the spermidine/spermine N1-acetyltransferase gene reduces the severity of renal ischemia/reperfusion injury

scientific article

Reduction in polyamine catabolism leads to spermine-mediated airway epithelial injury and induces asthma features

scientific article published on 01 October 2018

Regulation of Polyamine Metabolism by Curcumin for Cancer Prevention and Therapy

scientific article published on 18 December 2017

Self-immolative nanoparticles for simultaneous delivery of microRNA and targeting of polyamine metabolism in combination cancer therapy

scientific article published on 22 December 2016

Spermidine/spermine N1-acetyltransferase (SSAT) activity in human small-cell lung carcinoma cells following transfection with a genomic SSAT construct

scientific article published on July 2003

Targeting hexokinase 2 inhibition promotes radiosensitization in HPV16 E7-induced cervical cancer and suppresses tumor growth.

scientific article

Targeting polyamine metabolism for cancer therapy and prevention

scientific article published on October 2016

The re-expression of the epigenetically silenced e-cadherin gene by a polyamine analogue lysine-specific demethylase-1 (LSD1) inhibitor in human acute myeloid leukemia cell lines

scientific article published on 19 March 2013

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