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List of works by Stine Pedersen

12th Acta Physiologica International Symposium "cell volume control in health and disease.".

scientific article

3D multicellular models to study the regulation and roles of acid-base transporters in breast cancer

scientific article published on 01 December 2019

A novel NHE1 from red blood cells of the winter flounder: regulation by multiple signaling pathways.

scientific article published on January 2004

A phosphorylation-motif for tuneable helix stabilisation in intrinsically disordered proteins - Lessons from the sodium proton exchanger 1 (NHE1).

scientific article published on 26 May 2017

A unifying mechanism for cancer cell death through ion channel activation by HAMLET.

scientific article

ANO1 (TMEM16A) in pancreatic ductal adenocarcinoma (PDAC)

scientific article

Acid-base transport in pancreatic cancer: molecular mechanisms and clinical potential.

scientific article published on 26 August 2014

Activation of PLA2 isoforms by cell swelling and ischaemia/hypoxia.

scientific article

Alternating pH landscapes shape epithelial cancer initiation and progression: Focus on pancreatic cancer.

scientific article

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Networks in Cancer

scientific article

Assessing Cell Viability and Death in 3D Spheroid Cultures of Cancer Cells

scientific article published on 16 June 2019

Cancer Cell Acid Adaptation Gene Expression Response Is Correlated to Tumor-Specific Tissue Expression Profiles and Patient Survival

scientific article published on 05 August 2020

Cell cycle-dependent activity of the volume- and Ca2+-activated anion currents in Ehrlich lettre ascites cells

scientific article published on March 2007

Cell swelling activates cloned Ca2+-activated K+ channels: a role for the F-actin cytoskeleton

scientific article published on 01 September 2003

Cell volume homeostatic mechanisms: effectors and signalling pathways

scientific article published on November 9, 2010

Cell volume regulation and signaling in 3T3-L1 pre-adipocytes and adipocytes: on the possible roles of caveolae, insulin receptors, FAK and ERK1/2.

scientific article published on 16 December 2011

Cell volume regulation in epithelial physiology and cancer

scientific article published on 30 August 2013

Cholesterol modulates the volume-regulated anion current in Ehrlich-Lettre ascites cells via effects on Rho and F-actin

scientific article published on 10 May 2006

Comparative biology of the ubiquitous Na+/H+ exchanger, NHE1: lessons from erythrocytes.

scientific article published in July 2004

Constitutively active ErbB2 regulates cisplatin-induced cell death in breast cancer cells via pro- and antiapoptotic mechanisms

scientific article published on 20 August 2014

Contribution of Na+,HCO3(-)-cotransport to cellular pH control in human breast cancer: a role for the breast cancer susceptibility locus NBCn1 (SLC4A7).

scientific article

Corrigendum: Acid-base transport in pancreatic cancer: Molecular mechanisms and clinical potential

scientific article

Disrupting Na⁺, HCO₃⁻-cotransporter NBCn1 (Slc4a7) delays murine breast cancer development.

scientific article published on 27 July 2015

Dynamics of Ca 2+ i and pH i in Ehrlich ascites tumor cells after Ca 2+ -mobilizing agonists or exposure to hypertonic solution

article

EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms

scientific article

Effectors and signaling events activated by cell shrinkage in ehrlich ascites tumor cells: implications for cell proliferation and programmed cell death.

scientific article published on January 2004

Effects of oxygen-glucose deprivation (OGD) on barrier properties and mRNA transcript levels of selected marker proteins in brain endothelial cells/astrocyte co-cultures

scientific article published on 19 August 2019

ErbB2 upregulates the Na+,HCO3(-)-cotransporter NBCn1/SLC4A7 in human breast cancer cells via Akt, ERK, Src, and Kruppel-like factor 4.

scientific article published on 2 October 2013

Gram-scale solution-phase synthesis of selective sodium bicarbonate co-transport inhibitor S0859: in vitro efficacy studies in breast cancer cells.

scientific article published on 27 August 2012

H-ras transformation sensitizes volume-activated anion channels and increases migratory activity of NIH3T3 fibroblasts

scientific article published on 20 October 2007

HER2 and p95HER2 differentially regulate miRNA expression in MCF-7 breast cancer cells and downregulate MYB proteins through miR-221/222 and miR-503

scientific article published on 04 March 2019

HER2-encoded mir-4728 forms a receptor-independent circuit with miR-21-5p through the non-canonical poly(A) polymerase PAPD5.

scientific article published on 18 October 2016

HL-1 mouse cardiomyocyte injury and death after simulated ischemia and reperfusion: roles of pH, Ca2+-independent phospholipase A2, and Na+/H+ exchange

scientific article published on 4 March 2009

Heat shock protein 70 inhibits shrinkage-induced programmed cell death via mechanisms independent of effects on cell volume-regulatory membrane transport proteins.

scientific article published on 31 August 2004

Hyperosmotic stress regulates the distribution and stability of myocardin-related transcription factor, a key modulator of the cytoskeleton

scientific article published on 10 October 2012

Hyperosmotic stress strongly potentiates serum response factor (SRF)-dependent transcriptional activity in ehrlich lettré ascites cells through a mechanism involving p38 mitogen-activated protein kinase

scientific article published on 01 November 2011

Induction of group VIA phospholipase A2 activity during in vitro ischemia in C2C12 myotubes is associated with changes in the level of its splice variants

scientific article published on 5 September 2007

Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment.

scientific article published on 03 February 2014

Intracellular pH gradients in migrating cells

scientific article published on 9 December 2010

Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes

scientific article

Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration

scientific article

Ion channels and transporters in cancer: pathophysiology, regulation, and clinical potential

scientific article published on 9 January 2013

Luminescent dual sensors reveal extracellular pH-gradients and hypoxia on chronic wounds that disrupt epidermal repair.

scientific article

MCT1 and MCT4 Expression and Lactate Flux Activity Increase During White and Brown Adipogenesis and Impact Adipocyte Metabolism.

scientific article published on 12 October 2017

Mechanisms of pHi regulation studied in individual neurons cultured from mouse cerebral cortex

scientific article published in February 1998

Metabolism and microenvironment in cancer plasticity.

scientific article published on 15 February 2016

Modulation of the transient receptor potential vanilloid channel TRPV4 by 4alpha-phorbol esters: a structure-activity study

scientific article published on May 2009

Molecular basis for the binding and selective dephosphorylation of Na+/H+ exchanger 1 by calcineurin

scientific article published on 02 August 2019

Molecular cloning of NHE1 from winter flounder RBCs: activation by osmotic shrinkage, cAMP, and calyculin A.

scientific article published on 29 January 2003

Monocarboxylate Transporters MCT1 and MCT4 Regulate Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells.

scientific article published on 13 January 2016

Monovalent ions control proliferation of Ehrlich Lettre ascites cells

scientific article published on 30 June 2010

Multiple PLA2 isoforms regulate taurine release in NIH3T3 mouse fibroblasts

scientific article published on January 2006

Myocardin-related Transcription Factor Regulates Nox4 Protein Expression: LINKING CYTOSKELETAL ORGANIZATION TO REDOX STATE.

scientific article published on 10 November 2015

NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: contributions to pHi regulation and chemotherapy resistance.

scientific article published on 11 June 2010

NHE1 inhibition by amiloride- and benzoylguanidine-type compounds. Inhibitor binding loci deduced from chimeras of NHE1 homologues with endogenous differences in inhibitor sensitivity

scientific article

Na+,HCO3–-cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in mice

article

On the role of TRPC1 in control of Ca2+ influx, cell volume, and cell cycle

scientific article

Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR-dependent processes

scientific article published on 8 September 2016

Osmosensory mechanisms in cellular and systemic volume regulation.

scientific article published on 18 August 2011

Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications.

scientific article

Osmotic shrinkage elicits FAK- and Src phosphorylation and Src-dependent NKCC1 activation in NIH3T3 cells

scientific article

PDGFRα signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90RSK and AKT signaling pathways

scientific article

PDGFRβ and oncogenic mutant PDGFRα D842V promote disassembly of primary cilia through a PLCγ- and AURKA-dependent mechanism

scientific article published on 19 August 2015

Patterned formation of enolate functional groups on the graphene basal plane

scientific article published on 01 November 2018

Physiology and pathophysiology of Na+/H+ exchange and Na+ -K+ -2Cl- cotransport in the heart, brain, and blood.

scientific article

Physiology of cell volume regulation in vertebrates.

scientific article

Physiology, pharmacology and pathophysiology of the pH regulatory transport proteins NHE1 and NBCn1: similarities, differences, and implications for cancer therapy.

scientific article published on January 2012

Possible interrelationship between changes in F-actin and myosin II, protein phosphorylation, and cell volume regulation in Ehrlich ascites tumor cells

scientific article

Profibrotic epithelial phenotype: a central role for MRTF and TAZ

scientific article published on 13 March 2019

Prolactin Signaling Stimulates Invasion via Na(+)/H(+) Exchanger NHE1 in T47D Human Breast Cancer Cells

scientific article

Prophylactic effect of citalopram in unipolar, recurrent depression: placebo-controlled study of maintenance therapy

scientific article published in April 2001

Propionic acid secreted from propionibacteria induces NKG2D ligand expression on human-activated T lymphocytes and cancer cells

scientific article

Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex

scientific article

Putting Warburg to work: how imaging of tumour acidosis could help predict metastatic potential in breast cancer

scientific article published on 01 December 2020

Regulation and roles of bicarbonate transporters in cancer

scientific article published on 16 April 2014

Regulation of mitogen-activated protein kinase pathways by the plasma membrane Na+/H+ exchanger, NHE1.

scientific article published on 12 December 2006

Regulation of the Pleuronectes americanus Na+/H+ exchanger by osmotic shrinkage, beta-adrenergic stimuli, and inhibition of Ser/Thr protein phosphatases

scientific article published in January 2006

Regulation of the expression and subcellular localization of the taurine transporter TauT in mouse NIH3T3 fibroblasts

scientific article published on December 2004

Response to Schushan et al.: Two Conflicting NHE1 Model Structures: Compatibility with Experimental Data and Implications for the Transport Mechanism.

scientific article published in May 2011

Rho family GTP binding proteins are involved in the regulatory volume decrease process in NIH3T3 mouse fibroblasts

scientific article published on June 2002

Role of the F-actin cytoskeleton in the RVD and RVI processes in Ehrlich ascites tumor cells.

scientific article

Roles of Na+/H+ exchange in regulation of p38 mitogen-activated protein kinase activity and cell death after chemical anoxia in NIH3T3 fibroblasts

scientific article published on 3 March 2007

Roles of pH and the Na+/H+ exchanger NHE1 in cancer: From cell biology and animal models to an emerging translational perspective?

scientific article published on 19 December 2016

Roles of pH in control of cell proliferation

scientific article published on 25 March 2018

Roles of phospholipase A2 isoforms in swelling- and melittin-induced arachidonic acid release and taurine efflux in NIH3T3 fibroblasts

scientific article published on 19 July 2006

Sensors and Signal Transduction in the Activation of Cell Volume Regulatory Ion Transport Systems

scientific article published on 01 January 1998

Sensors and signal transduction pathways in vertebrate cell volume regulation.

scientific article published on January 2006

Separate Swelling- and Ca 2+ -activated Anion Currents in Ehrlich Ascites Tumor Cells

scientific article published on 01 May 1998

Shrinkage insensitivity of NKCC1 in myosin II-depleted cytoplasts from Ehrlich ascites tumor cells

scientific article

Shrinkage-induced Activation of the Na + /H + Exchanger in Ehrlich Ascites Tumor Cells: Mechanisms Involved in the Activation and a Role for the Exchanger in Cell Volume Regulation

scientific article published on 01 January 1996

Single point mutations of aromatic residues in transmembrane helices 5 and -6 differentially affect TRPV4 activation by 4α-PDD and hypotonicity: implications for the role of the pore region in regulating TRPV4 activity

scientific article published on 21 November 2013

Structural Modeling and Electron Paramagnetic Resonance Spectroscopy of the Human Na+/H+ Exchanger Isoform 1, NHE1

scientific article published on October 25, 2010

Structural dynamics and regulation of the mammalian SLC9A family of Na⁺/H⁺ exchangers

scientific article

Swelling-induced arachidonic acid release via the 85-kDa cPLA2 in human neuroblastoma cells

scientific article published on March 1998

TGF-β1 regulates the expression and transcriptional activity of TAZ protein via a Smad3-independent, myocardin-related transcription factor-mediated mechanism

scientific article published on 24 July 2017

Temperature-dependent structural changes in intrinsically disordered proteins: formation of alpha-helices or loss of polyproline II?

scientific article published on August 2010

The Acidic Tumor Microenvironment as a Driver of Cancer

scientific article published on 15 November 2019

The Na+/H+ exchanger NHE1 in stress-induced signal transduction: implications for cell proliferation and cell death.

scientific article

The Na+/H+ exchanger NHE1 is required for directional migration stimulated via PDGFR-alpha in the primary cilium

scientific article published on April 2009

The Na+/H+ exchanger NHE1, but not the Na+, HCO3(-) cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2.

scientific article

The Na+/H+ exchanger, NHE1, differentially regulates mitogen-activated protein kinase subfamilies after osmotic shrinkage in Ehrlich Lettre Ascites cells

scientific article published on January 2007

The P2X7 receptor regulates cell survival, migration and invasion of pancreatic ductal adenocarcinoma cells

scientific article

The SLC9A-C Mammalian Na+/H+ Exchanger Family: Molecules, Mechanisms, and Physiology

scientific article published on 01 October 2019

The Vacuolar H+ ATPase α3 Subunit Negatively Regulates Migration and Invasion of Human Pancreatic Ductal Adenocarcinoma Cells

scientific article published on 18 February 2020

The acid-base transport proteins NHE1 and NBCn1 regulate cell cycle progression in human breast cancer cells

scientific article published on 13 July 2018

The cardioprotective effect of brief acidic reperfusion after ischemia in perfused rat hearts is not mimicked by inhibition of the Na(+)/H(+) exchanger NHE1.

scientific article published on 16 August 2011

The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells.

scientific article published on 16 May 2015

The human Na(+)/H(+) exchanger 1 is a membrane scaffold protein for extracellular signal-regulated kinase 2

scientific article

The identification of a volume-regulated anion channel: an amazing Odyssey

scientific article published on 28 January 2015

The intracellular distal tail of the Na+/H+ exchanger NHE1 is intrinsically disordered: implications for NHE1 trafficking

scientific article published on 8 April 2011

The net acid extruders NHE1, NBCn1 and MCT4 promote mammary tumor growth through distinct but overlapping mechanisms

scientific article

The γ-hydroxybutyric acid (GHB) analogue NCS-382 is a substrate for both monocarboxylate transporters subtypes 1 and 4

scientific article published on 20 December 2019

Trafficking, localization and degradation of the Na+,HCO3- co-transporter NBCn1 in kidney and breast epithelial cells.

scientific article published on 9 May 2018

Transient receptor potential channels in mechanosensing and cell volume regulation

scientific article published in January 2007

pH regulation in sensitive and multidrug resistant Ehrlich ascites tumor cells.

scientific article published in January 1998