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List of works by Joseph R Slupsky

A novel transgenic mouse strain expressing PKCβII demonstrates expansion of B1 and marginal zone B cell populations

scientific article published on 04 August 2020

Acetyl-boswellic acids are novel catalytic inhibitors of human topoisomerases I and IIalpha.

scientific article

Activated platelets induce tissue factor expression on human umbilical vein endothelial cells by ligation of CD40

scientific article published on 01 December 1998

Active Ras induces heterodimerization of cRaf and BRaf

scientific article (publication date: May 2001)

Analysis of CD9, CD32 and p67 signalling: use of degranulated platelets indicates direct involvement of CD9 and p67 in integrin activation

scientific article published on 01 February 1997

Anti-CD9 monoclonal antibodies induce homotypic adhesion of pre-B cell lines by a novel mechanism

scientific article published on March 1990

B-Cell Receptor Translocation to Lipid Rafts and Associated Signaling Differ between Prognostically Important Subgroups of Chronic Lymphocytic Leukemia

article

B-cell receptor signaling in chronic lymphocytic leukemia cells is regulated by overexpressed active protein kinase C II

scientific article published on 26 September 2006

Binding of Gbetagamma subunits to cRaf1 downregulates G-protein-coupled receptor signalling

scientific article published on September 1999

C-fms protein expression by B-cells, with particular reference to the hairy cells of hairy-cell leukaemia

scientific article published on 01 February 1993

CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells

scientific article

CLL Exosomes Modulate the Transcriptome and Behaviour of Recipient Stromal Cells and Are Selectively Enriched in miR-202-3p

scientific article published on 28 October 2015

Cancerous inhibitor of PP2A (CIP2A) at diagnosis of chronic myeloid leukemia is a critical determinant of disease progression

scientific article published on 13 April 2011

Central role of protein kinase Cepsilon in constitutive activation of ERK1/2 and Rac1 in the malignant cells of hairy cell leukemia

scientific article published on February 2007

Characterization of cardiac calsequestrin

scientific article

Differential expression and regulation of protease-activated receptors in human peripheral monocytes and monocyte-derived antigen-presenting cells

scientific article published on 12 June 2003

Does B cell receptor signaling in chronic lymphocytic leukaemia cells differ from that in other B cell types?

scientific article published on 02 July 2014

Enhancing BCR signals at the cell membrane

scientific article published in January 2015

Evidence that monoclonal antibodies against CD9 antigen induce specific association between CD9 and the platelet glycoprotein IIb-IIIa complex

scientific article published on 01 July 1989

Expression and activity of NOX5 in the circulating malignant B cells of hairy cell leukemia.

scientific article

Expression of functional sphingosine-1 phosphate receptor-1 is reduced by B cell receptor signaling and increased by inhibition of PI3 kinase δ but not SYK or BTK in chronic lymphocytic leukemia cells

scientific article

GTPgammaS-stimulated phospholipase D activation in human neutrophils occurs by protein kinase C-dependent and -independent pathways but not tyrosine kinases

scientific article published on 01 March 1996

Glucocorticoid resistance in chronic lymphocytic leukaemia is associated with a failure of upregulated Bim/Bcl-2 complexes to activate Bax and Bak.

scientific article

Ibrutinib is safer than we think

scientific article published on 01 May 2019

Immunohistochemical analysis indicates that the anatomical location of B-cell non-Hodgkin's lymphoma is determined by differentially expressed chemokine receptors, sphingosine-1-phosphate receptors and integrins

scientific article published on April 2015

LCK is an important mediator of B-cell receptor signaling in chronic lymphocytic leukemia cells

scientific article published on 15 March 2013

Lck is a relevant target in chronic lymphocytic leukaemia cells whose expression variance is unrelated to disease outcome.

scientific article published in December 2017

Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development

scientific article published on 01 April 2020

Mitogenic signaling of Ras is regulated by differential interaction with Raf isozymes

scientific article

Monoclonal antibodies reactive with hairy cell leukemia

scientific article published on 01 July 1989

Multiplexed profiling of RNA and protein expression signatures in individual cells using flow or mass cytometry

scientific article published on 06 February 2019

Myristic acid is incorporated into the two acylatable domains of the functional glycoprotein CD9 in ester, but not in amide bonds

scientific article published on June 1990

New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome

scientific article published on 18 December 2017

Platelet activation by immobilized monoclonal antibody: evidence for a CD9 proximal signal

scientific article published on 01 October 1991

Properties of fibrinogen cleaved by Jararhagin, a metalloproteinase from the venom of Bothrops jararaca

scientific article published on 01 August 1994

Regulation of hairy-cell survival through constitutive activation of mitogen-activated protein kinase pathways

scientific article published in April 2003

Respiratory syncytial virus infection of airway epithelial cells, in vivo and in vitro, supports pulmonary antibody responses by inducing expression of the B cell differentiation factor BAFF.

scientific article published on 21 September 2012

Response of hairy cells to IFN-alpha involves induction of apoptosis through autocrine TNF-alpha and protection by adhesion

scientific article

Role of Fc gamma RII in platelet activation by monoclonal antibodies

scientific article published on 01 May 1992

The B lymphocyte differentiation factor (BAFF) is expressed in the airways of children with CF and in lungs of mice infected with Pseudomonas aeruginosa

scientific article

The Platelet Antigens CD9, CD42 and Integrin alphaIIbbetaIIIa Can be Topographically Associated and Transduce Functionally Similar Signals

scientific article (publication date: 15 February 1997)

The functional cell surface glycoprotein CD9 is distinguished by being the major fatty acid acylated and a major iodinated cell-surface component of the human platelet.

scientific article

The functional glycoprotein CD9 is variably acylated: localization of the variably acylated region to a membrane-associated peptide containing the binding site for the agonistic monoclonal antibody 50H.19

scientific article published on 01 December 1988

The peanut-agglutinin (PNA)-binding surface components of malignant plasma cells

scientific article published on April 1993

The role of autocrine FGF-2 in the distinctive bone marrow fibrosis of hairy-cell leukemia (HCL).

scientific article published on 10 April 2003

Transcriptional mechanism of vascular endothelial growth factor-induced expression of protein kinase CβII in chronic lymphocytic leukaemia cells.

scientific article published on 24 February 2017

UHRF1 regulation of the Keap1-Nrf2 pathway in pancreatic cancer contributes to oncogenesis

scientific article published on 24 October 2015

Variable induction of PRDM1 and differentiation in chronic lymphocytic leukemia is associated with anergy.

scientific article

Vascular endothelial growth factor stimulates protein kinase CbetaII expression in chronic lymphocytic leukemia cells

scientific article published on 17 February 2010

c-Abl Expression in Chronic Lymphocytic Leukemia Cells: Clinical and Therapeutic Implications

article

c-Abl regulates Mcl-1 gene expression in chronic lymphocytic leukemia cells

scientific article published on 10 January 2011

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