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List of works by Simon J. Waddell

A Novel TetR-Like Transcriptional Regulator Is Induced in Acid-Nitrosative Stress and Controls Expression of an Efflux Pump in Mycobacteria

scientific article

A non-canonical mismatch repair pathway in prokaryotes

scientific article published on 27 January 2017

Acquired predisposition to mycobacterial disease due to autoantibodies to IFN-gamma

scientific article published on 25 August 2005

Adjusting to a new home: Mycobacterium tuberculosis gene expression in response to an intracellular lifestyle

scientific article published on December 2009

Antimicrobial treatment improves mycobacterial survival in nonpermissive growth conditions

scientific article published on 03 March 2014

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

scientific journal article

Characterisation of drug-resistant Mycobacterium tuberculosis mutations and transmission in Pakistan

scientific article published on 11 May 2022

Childhood tuberculosis is associated with decreased abundance of T cell gene transcripts and impaired T cell function.

scientific article

Contrasting transcriptional responses of a virulent and an attenuated strain of Mycobacterium tuberculosis infecting macrophages

scientific article

Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum

scientific article

Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel

scientific article published on 24 May 2019

Dissecting interferon-induced transcriptional programs in human peripheral blood cells

scientific article

Distance-based differential analysis of gene curves

scientific article

Effects of low incubation temperatures on the bactericidal activity of anti-tuberculosis drugs

scientific article published on 11 November 2010

Examining the basis of isoniazid tolerance in nonreplicating Mycobacterium tuberculosis using transcriptional profiling.

scientific article

Identification of a series of hair-cell MET channel blockers that protect against aminoglycoside-induced ototoxicity

scientific article published on 08 April 2021

Identification of antigens presented by MHC for vaccines against tuberculosis

scientific article published on 03 January 2020

Identification of ion-channel modulators that protect against aminoglycoside-induced hair cell death.

scientific article published on 21 December 2017

Inactivation of polyketide synthase and related genes results in the loss of complex lipids in Mycobacterium tuberculosis H37Rv

scientific journal article

Increased transcription of a potential sigma factor regulatory gene Rv1364c in Mycobacterium bovis BCG while residing in macrophages indicates use of alternative promoters.

scientific article published in April 2004

Intestinal injury and endotoxemia in children undergoing surgery for congenital heart disease

scientific article published on 25 August 2011

Methionine sulfoximine resistance in Mycobacterium tuberculosis is due to a single nucleotide deletion resulting in increased expression of the major glutamine synthetase, GlnA1.

scientific article

Microarray analysis of defined Mycobacterium tuberculosis populations using RNA amplification strategies.

scientific article

Microarray analysis of whole genome expression of intracellular Mycobacterium tuberculosis

scientific article published on May 2007

Mycobacterial p(1)-type ATPases mediate resistance to zinc poisoning in human macrophages

scientific article published on September 2011

Myocardial depressant effects of interleukin 6 in meningococcal sepsis are regulated by p38 mitogen-activated protein kinase

scientific article published in July 2011

Oleoyl coenzyme A regulates interaction of transcriptional regulator RaaS (Rv1219c) with DNA in mycobacteria

scientific article

Potassium availability triggers Mycobacterium tuberculosis transition to, and resuscitation from, non-culturable (dormant) states

scientific article

Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages

scientific article

Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy

scientific article

Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the transcriptional regulator Lsr2 at threonine 112

scientific article published on 10 October 2019

Quantification of global transcription patterns in prokaryotes using spotted microarrays

scientific article

RNA profiling in host-pathogen interactions

scientific article

Reprogramming the Mycobacterium tuberculosis transcriptome during pathogenesis

scholarly article by Simon J. Waddell published March 2010 in Drug discovery today. Disease mechanisms

The use of microarray analysis to determine the gene expression profiles of Mycobacterium tuberculosis in response to anti-bacterial compounds.

scientific article

Transcriptional Profiling Mycobacterium tuberculosis from Patient Sputa

scientific article published in January 2018

Understanding anti-tuberculosis drug efficacy: rethinking bacterial populations and how we model them

scientific article

Use of DNA Arrays to Study Transcriptional Responses to Antimycobacterial Compounds

article

Whole genome analysis using microarrays

scientific article published on January 2009

Whole genome sequencing of drug resistant Mycobacterium tuberculosis isolates from a high burden tuberculosis region of North West Pakistan

scientific article published on 18 October 2019

cDNA-RNA subtractive hybridization reveals increased expression of mycocerosic acid synthase in intracellular Mycobacterium bovis BCG.

scientific article

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