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List of works by Pauline A van Schouwenburg

A novel method for the detection of antibodies to adalimumab in the presence of drug reveals “hidden” immunogenicity in rheumatoid arthritis patients

scientific article published on 09 September 2010

Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation.

scientific article

Antigen Receptor Galaxy: A User-Friendly, Web-Based Tool for Analysis and Visualization of T and B Cell Receptor Repertoire Data

scientific article

Application of whole genome and RNA sequencing to investigate the genomic landscape of common variable immunodeficiency disorders

scientific article

Chronic mucocutaneous candidiasis: characterization of a family with STAT-1 gain-of-function and development of an ex-vivo assay for Th17 deficiency of diagnostic utility

scientific article published on December 2015

Development of antidrug antibodies against adalimumab and association with disease activity and treatment failure during long-term follow-up

scientific article

Evaluation of the Antigen-Experienced B-Cell Receptor Repertoire in Healthy Children and Adults

scientific article published on 17 October 2016

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

scientific article

Functional analysis of the anti-adalimumab response using patient-derived monoclonal antibodies

scientific article

Genetic defects in PI3Kδ affect B-cell differentiation and maturation leading to hypogammaglobulineamia and recurrent infections.

scientific article published on 16 January 2017

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

scientific article

Hypomorphic function and somatic reversion of DOCK8 cause combined immunodeficiency without hyper-IgE

scientific article published on 8 December 2015

IgG4 Production Against Adalimumab During Long Term Treatment of RA Patients

scientific article published on 24 May 2012

Immunogenicity of anti-TNF biologic therapies for rheumatoid arthritis

scientific article published on 12 February 2013

Long-term measurement of anti-adalimumab using pH-shift-anti-idiotype antigen binding test shows predictive value and transient antibody formation

scientific article published on 07 January 2013

Monoclonal anti-citrullinated protein antibodies selected on citrullinated fibrinogen have distinct targets with different cross-reactivity patterns

scientific article published on 22 December 2012

Nanomolar to sub-picomolar affinity measurements of antibody-antigen interactions and protein multimerizations: fluorescence-assisted high-performance liquid chromatography

scientific article

Neutralizing capacity of monoclonal and polyclonal anti-natalizumab antibodies: The immune response to antibody therapeutics preferentially targets the antigen-binding site

scientific article published on 04 October 2016

The TH1 phenotype of follicular helper T cells indicates an IFN-γ-associated immune dysregulation in patients with CD21low common variable immunodeficiency.

scientific article published on 26 May 2017

The presence or absence of antibodies to infliximab or adalimumab determines the outcome of switching to etanercept

scientific article published on 10 November 2010

Using monoclonal antibodies as an international standard for the measurement of anti-adalimumab antibodies

scientific article published on 28 December 2015

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