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List of works by Andrew Reay Mackay

A pilot study of alternative TrkAIII splicing in Merkel cell carcinoma: a potential oncogenic mechanism and novel therapeutic target

scientific article published on 22 October 2019

Activation of MMP-2 by human GCT23 giant cell tumour cells induced by osteopontin, bone sialoprotein and GRGDSP peptides is RGD and cell shape change dependent.

scientific article published in July 1998

Alendronate promotes plasmin-mediated MMP-9 inactivation by exposing cryptic plasmin degradation sites within the MMP-9 catalytic domain

scientific article published on 4 June 2012

All-trans-retinoic acid induces nuclear factor kappaB activation and matrix metalloproteinase-9 expression and enhances basement membrane invasivity of differentiation-resistant human SK-N-BE 9N neuroblastoma Cells

scientific article published in August 2002

Alternative TrkAIII splicing: a potential regulated tumor-promoting switch and therapeutic target in neuroblastoma.

scientific article

Constitutive autotaxin transcription by Nmyc-amplified and non-amplified neuroblastoma cells is regulated by a novel AP-1 and SP-mediated mechanism and abrogated by curcumin.

scientific article

Discovery, characterization and potential roles of a novel NF-YAx splice variant in human neuroblastoma

scientific article published on 05 December 2019

Effect of a lymphocyte-derived pro-inflammatory factor on carrageenan pleurisy in the rat

scientific article published on 01 January 1984

Gelatinase B/MMP-9 in Tumour Pathogenesis and Progression

scientific article

Hypoxia-induced alternative splicing: the 11th Hallmark of Cancer

scientific article published on 15 June 2020

Identification of the 72-kDa (MMP-2) and 92-kDa (MMP-9) gelatinase/type IV collagenase in preparations of laminin and Matrigel

scientific article published on 01 December 1993

Increased chemiluminescence of polymorphonuclear leucocytes from patients with progressive systemic sclerosis

scientific article published on 01 March 1986

Increased matrix metalloproteinase-9 secretion in short-term tissue cultures of prostatic tumor cells

scientific article published in October 1996

Inhibition of human MDA-MB-231 breast cancer cell invasion by matrix metalloproteinase 3 involves degradation of plasminogen

scientific article published in September 2002

Mapping of receptor binding sites on IL-1 beta by reconstruction of IL-1ra-like domains

scientific article published on 01 November 1995

Mode of formation of synovial villi

scientific article published on October 1983

NGF sensitizes TrkA SH-SY5Y neuroblastoma cells to TRAIL-induced apoptosis.

scientific article published on February 2016

Nifedipine in the treatment of Raynaud's phenomenon in patients with systemic sclerosis

scientific article published on August 1987

Pyrrolopyrimidine c-Src inhibitors reduce growth, adhesion, motility and invasion of prostate cancer cells in vitro.

scientific article published in September 2003

Ras levels and metalloproteinase activity in normal versus neoplastic rat mammary tissues

scientific article published on March 1991

Reconstitution of TIMP-2 expression in SH-SY5Y neuroblastoma cells by 5-azacytidine is mediated transcriptionally by NF-Y through an inverted CCAAT site

scientific article published in June 2003

Retinoic acid-enhanced invasion through reconstituted basement membrane by human SK-N-SH neuroblastoma cells involves membrane-associated tissue-type plasminogen activator

scientific article

Retrograde TrkAIII transport from ERGIC to ER: a re-localisation mechanism for oncogenic activity.

scientific article

Studies into the mode of action of non-steroidal anti-inflammatory drugs using a model of facsimile synovium

scientific article published on 01 March 1984

The TrkAIII oncoprotein inhibits mitochondrial free radical ROS-induced death of SH-SY5Y neuroblastoma cells by augmenting SOD2 expression and activity at the mitochondria, within the context of a tumour stem cell-like phenotype

scientific article

The alternative TrkAIII splice variant targets the centrosome and promotes genetic instability

scientific article

The effects of levan on the acute inflammatory response

scientific article published on April 1984

The neuroblastoma tumour-suppressor TrkAI and its oncogenic alternative TrkAIII splice variant exhibit geldanamycin-sensitive interactions with Hsp90 in human neuroblastoma cells

scientific article

The oncogenic neurotrophin receptor tropomyosin-related kinase variant, TrkAIII.

scientific article

The role of plasma factors in the adherence of leucocytes to vascular endothelial cells

scientific article published on 01 May 1983

The transition from acute to chronic inflammation

scientific article published on 01 July 1985

Thioredoxin alters the matrix metalloproteinase/tissue inhibitors of metalloproteinase balance and stimulates human SK-N-SH neuroblastoma cell invasion

scientific article published on 01 January 2001

Thioredoxin inhibits microvascular endothelial capillary tubule formation.

scientific article published on December 2003

Thioredoxin stimulates MMP-9 expression, de-regulates the MMP-9/TIMP-1 equilibrium and promotes MMP-9 dependent invasion in human MDA-MB-231 breast cancer cells

scientific article published on 28 September 2011

Tissue inhibitor of metalloproteinase-2 protection of matrix metalloproteinase-2 from degradation by plasmin is reversed by divalent cation chelator EDTA and the bisphosphonate alendronate.

scientific article published in July 1998

Transcriptional regulation of intercellular adhesion molecule 1 by phorbol ester in human neuroblastoma cell line SK-N-SH involves jun- and fos-containing activator protein 1 site binding complex(es).

scientific article published on July 1997

Transcriptional up-regulation of matrix metalloproteinase-9 expression during spontaneous epithelial to neuroblast phenotype conversion by SK-N-SH neuroblastoma cells, involved in enhanced invasivity, depends upon GT-box and nuclear factor kappaB el

scientific article published on 01 May 1999

Transforming growth factor-beta1 enhances the invasiveness of human MDA-MB-231 breast cancer cells by up-regulating urokinase activity.

scientific article

TrkAIII expression in the thymus

scientific article published on 22 January 2007

TrkAIII promotes microtubule nucleation and assembly at the centrosome in SH-SY5Y neuroblastoma cells, contributing to an undifferentiated anaplastic phenotype

scientific article published on 6 June 2013

TrkAIII. A novel hypoxia-regulated alternative TrkA splice variant of potential physiological and pathological importance.

scientific article

bcl-2 over-expression enhances NF-kappaB activity and induces mmp-9 transcription in human MCF7(ADR) breast-cancer cells

scientific article

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