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Authors whose works are in public domain in at least one jurisdiction

List of works by Joshua J Ziarek

15N detection harnesses the slow relaxation property of nitrogen: Delivering enhanced resolution for intrinsically disordered proteins

scientific article published on 5 February 2018

A Locked, Dimeric CXCL12 Variant Effectively Inhibits Pulmonary Metastasis of CXCR4-Expressing Melanoma Cells Due to Enhanced Serum Stability ⬇️

scientific article published on August 6, 2012

Biased antagonism of CXCR4 avoids antagonist tolerance

article

Bicelle size modulates the rate of bacteriorhodopsin folding

scientific article published on 25 April 2018

Binding site identification and structure determination of protein-ligand complexes by NMR a semiautomated approach.

scientific article published on January 2011

Chemokine cooperativity is caused by competitive glycosaminoglycan binding.

scientific article

Discovery and characterization of a disulfide-locked C(2)-symmetric defensin peptide

scientific article

Examining weak protein-protein interactions in start codon recognition via NMR spectroscopy

scientific article published on 02 January 2014

Fragment-based optimization of small molecule CXCL12 inhibitors for antagonizing the CXCL12/CXCR4 interaction.

scientific article

Heparin Oligosaccharides Inhibit Chemokine (CXC Motif) Ligand 12 (CXCL12) Cardioprotection by Binding Orthogonal to the Dimerization Interface, Promoting Oligomerization, and Competing with the Chemokine (CXC Motif) Receptor 4 (CXCR4) N Terminus ⬇️

scientific article published on November 12, 2012

Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways

scientific article

Monomeric structure of the cardioprotective chemokine SDF-1/CXCL12

scientific article

NMR in the analysis of functional chemokine interactions and drug discovery ⬇️

scientific article published on January 1, 2012

New paradigms in chemokine receptor signal transduction: Moving beyond the two-site model.

scientific article published on 19 April 2016

Recent developments in solution nuclear magnetic resonance (NMR)-based molecular biology.

scientific article

Solution Structure of CCL21 and Identification of a Putative CCR7 Binding Site ⬇️

scientific article published on January 17, 2012

Structural analysis of a novel small molecule ligand bound to the CXCL12 chemokine

scientific article

Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation

scientific article published on 21 March 2017

Structure-based ligand discovery for the protein–protein interface of chemokine receptor CXCR4 ⬇️

scientific article published on March 19, 2012

Sulfopeptide probes of the CXCR4/CXCL12 interface reveal oligomer-specific contacts and chemokine allostery.

scientific article published on 26 June 2013

Sulfotyrosine recognition as marker for druggable sites in the extracellular space.

scientific article published on 8 June 2011

Targeting SDF-1/CXCL12 with a ligand that prevents activation of CXCR4 through structure-based drug design

scientific article

The CXC Chemokine Receptor 4 Ligands Ubiquitin and Stromal Cell-derived Factor-1α Function through Distinct Receptor Interactions ⬇️

scientific article published on July 13, 2011

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