List of works - Gary W. Miller

2017 Toxicological Sciences Paper of the Year

article

25-Hydroxyvitamin D depletion does not exacerbate MPTP-induced dopamine neuron damage in mice

scientific article

A Golden Anniversary for the National Institute of Environmental Health Sciences

scientific article published in November 2016

A fluorescent-based assay for live cell, spatially resolved assessment of vesicular monoamine transporter 2-mediated neurotransmitter transport.

scientific article published on 12 June 2012

A scalable workflow to characterize the human exposome

scientific article published on 22 September 2021

A vesicular sequestration to oxidative deamination shift in myocardial sympathetic nerves in Parkinson's disease

scientific article

Adenosine A2A receptor antagonism reverses inflammation-induced impairment of microglial process extension in a model of Parkinson's disease

scientific article

An exposomic framework to uncover environmental drivers of aging

Assessing Vesicular Monoamine Transport and Toxicity Using Fluorescent False Neurotransmitters

scientific article published on 30 December 2020

Association between polychlorinated biphenyls and Parkinson's disease neuropathology

scientific article

Bioinspired Honokiol Analogs and Their Evaluation for Activity on the Norepinephrine Transporter

Ch-Ch-Ch-Changes

Contemporary Reviews in Toxicology

article

Cross-species metabolomic analysis of tau- and DDT-related toxicity

scientific article published on 01 May 2022

Data sharing in toxicology: beyond show and tell

scientific article published on January 2015

Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson's disease

scientific article

Developmental pesticide exposure reproduces features of attention deficit hyperactivity disorder

scientific article

Developmental pyrethroid exposure disrupts molecular pathways for MAP kinase and circadian rhythms in mouse brain

scientific article published on 11 March 2024

Developmental pyrethroid exposure in mouse leads to disrupted brain metabolism in adulthood

scientific article published on 17 October 2023

Editor-in-Chief response to “FAIR-ifying the Exposome Journal: templates for chemical structures and transformations”

scientific article published in January 2022

Editorial: a toxicological transition.

scientific article

Exposome: a new field, a new journal

scientific article

Exposomics as a tool to investigate differences in health and disease by sex and gender

scientific article published in 2023

Exposomics: perfection not required

scientific article published in 2024

Exposure to the polybrominated diphenyl ether mixture DE-71 damages the nigrostriatal dopamine system: role of dopamine handling in neurotoxicity

scientific article published on 31 December 2012

From the Editor’s Desk

scientific article published on 01 December 2014

From the exposome to mechanistic understanding of chemical-induced adverse effects

scientific article

Fungal-derived semiochemical 1-octen-3-ol disrupts dopamine packaging and causes neurodegeneration

scientific article

GAIT-GM integrative cross-omics analyses reveal cholinergic defects in a C. elegans model of Parkinson’s disease

scientific article published on 16 July 2021

Genetic or Toxicant-Induced Disruption of Vesicular Monoamine Storage and Global Metabolic Profiling in Caenorhabditis elegans

scientific article published on 01 April 2021

Green chemistry as a leadership opportunity for toxicology: we must take the wheel

scientific article published on September 2014

High-resolution metabolomic profiling of Alzheimer's disease in plasma

scientific article published on 11 December 2019

Human Suction Blister Fluid Composition Determined Using High-Resolution Metabolomics.

scientific article published on 9 February 2018

Immunochemical analysis of the expression of SV2C in mouse, macaque and human brain

scientific article published on 21 December 2017

Immunochemical localization of vesicular monoamine transporter 2 (VMAT2) in mouse brain.

scientific article published on 8 November 2016

Improving Reproducibility in Toxicology

Increased Vesicular Monoamine Transporter 2 (VMAT2; Slc18a2) Protects against Methamphetamine Toxicity

scientific article published on 9 March 2015

Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits.

scientific article

Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in vivo

scientific article

Industrial toxicants and Parkinson's disease

scientific article published on 30 January 2012

Integrating the exposome into a multi-omic research framework

scientific article published in 2021

Large scale enzyme based xenobiotic identification for exposomics

scientific article published on 14 September 2021

Letters from Science Camp

Making Data Accessible: The Dryad Experience

scientific article published in January 2016

Membrane transporters as mediators of synaptic dopamine dynamics: implications for disease

scientific article published on 13 August 2016

Metabolic defects cause hyperactive mitochondria and Parkinson’s disease-like traits

scientific article published on 22 February 2020

Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria

scientific article published on 06 October 2020

Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits.

scientific article

More than Manuscripts: Reproducibility, Rigor, and Research Productivity in the Big Data Era.

scientific article

Parkinson's disease and the environment: Beyond pesticides

scientific article published on 01 June 2012

Preprints in Toxicology

scientific article published on February 2017

RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells

scientific article published on 11 January 2013

Reduced vesicular monoamine transport disrupts serotonin signaling but does not cause serotonergic degeneration

scientific article published on 28 September 2015

Reduced vesicular storage of catecholamines causes progressive degeneration in the locus ceruleus

scientific article

Reference Standardization for Mass Spectrometry and High-resolution Metabolomics Applications to Exposome Research

scientific article

Reproducibility Revisited: Reflections of an Editor

scientific article published on 01 June 2019

Restoration of Noradrenergic Function in Parkinson’s Disease Model Mice

scientific article published on 04 May 2021

Rotenone and paraquat perturb dopamine metabolism: A computational analysis of pesticide toxicity

scientific article

Sampling interstitial fluid from human skin using a microneedle patch

scientific article published on 01 November 2020

Science, Societies, and Society

Selective Enhancement of Dopamine Release in the Ventral Pallidum of Methamphetamine-Sensitized Mice

scientific article published on 8 August 2016

Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression.

scientific article

Seminar: Functional Exposomics and Mechanisms of Toxicity—Insights from Model Systems and NAMs

scientific article published in September 2024

Society of Toxicology Board of Publications Best Paper Award for 2015.

scientific article published on 25 February 2015

Society of Toxicology Board of Publications Best Paper Award for 2016.

scientific article published in April 2016

Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease.

scientific article published on 28 February 2017

The 53rd Annual Meeting of The Society of Toxicology . . . from Phoenix, Arizona

scientific article

The Exposome Paradigm in Human Health: Lessons from the Emory Exposome Summer Course ⬇️

scientific article published on 29 June 2017

The Exposome and Toxicology: A Win-Win Collaboration

scientific article published on 28 February 2022

The Importance of the Biological Impact of Exposure to the Concept of the Exposome

scientific article (publication date: October 2016)

The International Reach of Toxicology

scientific article published in June 2017

The Literature of Science

The Synaptic Vesicle Glycoprotein 2: Structure, Function, and Disease Relevance

scientific article published on 23 August 2019

The effect of air pollution on hospitalizations with Parkinson's disease among medicare beneficiaries nationwide

scientific article published on 24 October 2024

The exposome and health: Where chemistry meets biology

scientific article

The exposome and liver disease - how environmental factors affect liver health

scientific article published in August 2023

The exposome at NIEHS: from workshops to manuscripts

scientific article published in 2023

The nature of nurture: refining the definition of the exposome

scientific article

The vesicular monoamine transporter 2: an underexplored pharmacological target

scientific article published on 04 January 2014

Three Years After

ToxSci at 20

Toxicological Sciences: Measuring the True Impact of the Journal

article by Gary W. Miller published 25 August 2015 in Toxicological Sciences

Toxicology at the speed of light: an interview with Dr. Craig Venter

scientific article published on 25 February 2015

Toxicology: Cajun Style

Transport behavior of functionalized multi-wall carbon nanotubes in water-saturated quartz sand as a function of tube length.

scientific article

Tricyclic and tetracyclic antidepressants upregulate VMAT2 activity and rescue disease-causing VMAT2 variants

scientific article published in October 2024

Tricyclic and tetracyclic antidepressants upregulate VMAT2 activity and rescue disease-causing VMAT2 variants

scientific article published on 19 October 2023

Using the exposome to address gene-environment interactions in kidney disease

scientific article published on 11 May 2020

VMAT2 and Parkinson's disease: harnessing the dopamine vesicle

scientific article published on 14 September 2014

Vesicular Monoamine Transporter 2 (VMAT2) Level Regulates MPTP Vulnerability and Clearance of Excess Dopamine in Mouse Striatal Terminals.

scientific article published on 10 June 2016

Vesicular integrity in Parkinson's disease

scientific article

Vesicular monoamine transporter 2 mediates fear behavior in mice

scientific article published on 03 January 2020

List of works by Gary W. Miller

2017 Toxicological Sciences Paper of the Year

25-Hydroxyvitamin D depletion does not exacerbate MPTP-induced dopamine neuron damage in mice

A Golden Anniversary for the National Institute of Environmental Health Sciences

A fluorescent-based assay for live cell, spatially resolved assessment of vesicular monoamine transporter 2-mediated neurotransmitter transport.

A scalable workflow to characterize the human exposome

A vesicular sequestration to oxidative deamination shift in myocardial sympathetic nerves in Parkinson's disease

Adenosine A2A receptor antagonism reverses inflammation-induced impairment of microglial process extension in a model of Parkinson's disease

An exposomic framework to uncover environmental drivers of aging

Assessing Vesicular Monoamine Transport and Toxicity Using Fluorescent False Neurotransmitters

Association between polychlorinated biphenyls and Parkinson's disease neuropathology

Bioinspired Honokiol Analogs and Their Evaluation for Activity on the Norepinephrine Transporter

Ch-Ch-Ch-Changes

Contemporary Reviews in Toxicology

Cross-species metabolomic analysis of tau- and DDT-related toxicity

Data sharing in toxicology: beyond show and tell

Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson's disease

Developmental pesticide exposure reproduces features of attention deficit hyperactivity disorder

Developmental pyrethroid exposure disrupts molecular pathways for MAP kinase and circadian rhythms in mouse brain

Developmental pyrethroid exposure in mouse leads to disrupted brain metabolism in adulthood

Editor-in-Chief response to “FAIR-ifying the Exposome Journal: templates for chemical structures and transformations”

Editorial: a toxicological transition.

Exposome: a new field, a new journal

Exposomics as a tool to investigate differences in health and disease by sex and gender

Exposomics: perfection not required

Exposure to the polybrominated diphenyl ether mixture DE-71 damages the nigrostriatal dopamine system: role of dopamine handling in neurotoxicity

From the Editor’s Desk

From the exposome to mechanistic understanding of chemical-induced adverse effects

Fungal-derived semiochemical 1-octen-3-ol disrupts dopamine packaging and causes neurodegeneration

GAIT-GM integrative cross-omics analyses reveal cholinergic defects in a C. elegans model of Parkinson’s disease

Genetic or Toxicant-Induced Disruption of Vesicular Monoamine Storage and Global Metabolic Profiling in Caenorhabditis elegans

Green chemistry as a leadership opportunity for toxicology: we must take the wheel

High-resolution metabolomic profiling of Alzheimer's disease in plasma

Human Suction Blister Fluid Composition Determined Using High-Resolution Metabolomics.

Immunochemical analysis of the expression of SV2C in mouse, macaque and human brain

Immunochemical localization of vesicular monoamine transporter 2 (VMAT2) in mouse brain.

Improving Reproducibility in Toxicology

Increased Vesicular Monoamine Transporter 2 (VMAT2; Slc18a2) Protects against Methamphetamine Toxicity

Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits.

Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in vivo

Industrial toxicants and Parkinson's disease

Integrating the exposome into a multi-omic research framework

Large scale enzyme based xenobiotic identification for exposomics

Letters from Science Camp

Making Data Accessible: The Dryad Experience

Membrane transporters as mediators of synaptic dopamine dynamics: implications for disease

Metabolic defects cause hyperactive mitochondria and Parkinson’s disease-like traits

Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria

Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits.

More than Manuscripts: Reproducibility, Rigor, and Research Productivity in the Big Data Era.

Parkinson's disease and the environment: Beyond pesticides

Preprints in Toxicology

RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells

Reduced vesicular monoamine transport disrupts serotonin signaling but does not cause serotonergic degeneration

Reduced vesicular storage of catecholamines causes progressive degeneration in the locus ceruleus

Reference Standardization for Mass Spectrometry and High-resolution Metabolomics Applications to Exposome Research

Reproducibility Revisited: Reflections of an Editor

Restoration of Noradrenergic Function in Parkinson’s Disease Model Mice

Rotenone and paraquat perturb dopamine metabolism: A computational analysis of pesticide toxicity

Sampling interstitial fluid from human skin using a microneedle patch

Science, Societies, and Society

Selective Enhancement of Dopamine Release in the Ventral Pallidum of Methamphetamine-Sensitized Mice

Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression.

Seminar: Functional Exposomics and Mechanisms of Toxicity—Insights from Model Systems and NAMs

Society of Toxicology Board of Publications Best Paper Award for 2015.

Society of Toxicology Board of Publications Best Paper Award for 2016.

Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease.

The 53rd Annual Meeting of The Society of Toxicology . . . from Phoenix, Arizona

The Exposome Paradigm in Human Health: Lessons from the Emory Exposome Summer Course ⬇️

The Exposome and Toxicology: A Win-Win Collaboration

The Importance of the Biological Impact of Exposure to the Concept of the Exposome

The International Reach of Toxicology

The Literature of Science

The Synaptic Vesicle Glycoprotein 2: Structure, Function, and Disease Relevance

The effect of air pollution on hospitalizations with Parkinson's disease among medicare beneficiaries nationwide

The exposome and health: Where chemistry meets biology

The exposome and liver disease - how environmental factors affect liver health

The exposome at NIEHS: from workshops to manuscripts

The nature of nurture: refining the definition of the exposome

The vesicular monoamine transporter 2: an underexplored pharmacological target