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List of works by Carla Fiorentini

2-Chloro-adenosine Induces a Glutamate-Dependent Calcium Response in C2C12 Myotubes

scientific article published in 2000

A multinucleating Escherichia coli cytotoxin perturbs cell cycle in cultured epithelial cells.

scientific article published on 14 September 2006

Actin cytoskeleton as a target for 2-chloro adenosine: evidence for induction of apoptosis in C2C12 myoblastic cells

scientific article published on September 1997

Activation of Rho GTPases triggers structural remodeling and functional plasticity in the adult rat visual cortex

scientific article published on October 2011

Adenosine- and 2-chloro-adenosine-induced cytopathic effects on myoblastic cells and myotubes: involvement of different intracellular mechanisms

scientific article published on August 2000

An Escherichia coli cytotoxin increases superoxide anion generation via rac in epithelial cells

scientific article published on May 2001

Antisense to glucosylceramide synthase in human neuroepithelioma affects cell growth but not apoptosis

scientific article published on 01 June 2002

Bacterial protein toxins in human cancers.

scientific article

Bacterial protein toxins: current and potential clinical use.

scientific article published on January 2008

CNF1 Enhances Brain Energy Content and Counteracts Spontaneous Epileptiform Phenomena in Aged DBA/2J Mice

scientific article

CNF1 improves astrocytic ability to support neuronal growth and differentiation in vitro.

scientific article

CNF1 increases brain energy level, counteracts neuroinflammatory markers and rescues cognitive deficits in a murine model of Alzheimer's disease

scientific article

Cell injury and death caused by bacterial protein toxins

scientific article published on December 1992

Cell-to-cell propagation of the bacterial toxin CNF1 via extracellular vesicles: potential impact on the therapeutic use of the toxin.

scientific article published on 5 November 2015

Cholesterol perturbing agents inhibit NMDA-dependent calcium influx in rat hippocampal primary culture.

scientific article

Clostridium difficile toxin A induces multinucleation in the human leukemic T cell line JURKAT.

scientific article published on April 1992

Clostridium difficile toxin B causes apoptosis in epithelial cells by thrilling mitochondria. Involvement of ATP-sensitive mitochondrial potassium channels.

scientific article published on 12 January 2007

Clostridium difficile toxin B induces apoptosis in intestinal cultured cells

scientific article

Clostridium difficile: an Update on Virulence Mechanisms

scientific article published on 01 December 1996

Cnf1 Variants Endowed with the Ability to Cross the Blood-Brain Barrier: A New Potential Therapeutic Strategy for Glioblastoma

scientific article published on 04 May 2020

Cytoskeletal changes induced in HEp-2 cells by the cytotoxic necrotizing factor of Escherichia coli

scientific article published in January 1988

Cytotoxic necrotizing factor 1 enhances reactive oxygen species-dependent transcription and secretion of proinflammatory cytokines in human uroepithelial cells

scientific article

Cytotoxic necrotizing factor 1 hinders skeletal muscle differentiation in vitro by perturbing the activation/deactivation balance of Rho GTPases.

scientific article

Dissection of Pathways Implicated in Integrin-mediated Actin Cytoskeleton Assembly

scientific article published in Journal of Biological Chemistry

Effects of Clostridium Difficile toxins A and B on cytoskeleton organization in HEp-2 cells: A comparative morphological study

scientific article published on 01 January 1989

Effects of HIV-1 Nef on virus co-receptor expression and cytokine release in human bladder, laryngeal, and intestinal epithelial cell lines.

scientific article published on June 2011

Effects of the Escherichia coli Bacterial Toxin Cytotoxic Necrotizing Factor 1 on Different Human and Animal Cells: A Systematic Review

scientific article published in 2021

Effects of the new-identified amphibole fluoro-edenite in lung epithelial cells.

scientific article published on October 2003

Electrophysiology of glioma: a Rho GTPase-activating protein reduces tumor growth and spares neuron structure and function.

scientific article published on 13 June 2016

Enhancement of cell-mediated cytotoxicity by Clostridium difficile toxin A: an in vitro study

scientific article published on January 1991

Enhancement of learning and memory after activation of cerebral Rho GTPases

scholarly article

Enhancement of mitochondrial ATP production by the Escherichia coli cytotoxic necrotizing factor 1.

scientific article

Epithelial cells and expression of the phagocytic marker CD68: scavenging of apoptotic bodies following Rho activation

scientific article

Epithelial cells challenged with a Rac-activating E. coli cytotoxin acquire features of professional phagocytes.

scientific article

Escherichia coli cytotoxic necrotizing factor 1 (CNF1), a toxin that activates the Rho GTPase

scientific article published in August 1997

Escherichia coli cytotoxic necrotizing factor 1 blocks cell cycle G2/M transition in uroepithelial cells

scientific article published on July 2006

Escherichia coli cytotoxic necrotizing factor 1 effaces microvilli and decreases transmigration of polymorphonuclear leukocytes in intestinal T84 epithelial cell monolayers

scientific article published on June 1998

Evidence for cytoskeletal changes secondary to plasma membrane functional alterations in the in vitro cell response to Clostridium perfringens epsilon-toxin.

scientific article published on May 2003

Eye Drop Instillation of the Rac1 Modulator CNF1 Attenuates Retinal Gliosis and Ameliorates Visual Performance in a Rat Model of Hypertensive Retinopathy

scientific article published on 23 May 2019

Fine environmental particulate engenders alterations in human lung epithelial A549 cells.

scientific article published on May 2004

Free radical release in C6 glial cells enriched in hexacosanoic acid: implication for X-linked adrenoleukodystrophy pathogenesis.

scientific article published on March 2004

Glutamate-induced calcium increase in myotubes depends on up-regulation of a sodium-dependent transporter

scientific article published in September 2002

Gut Microbiota and Colon Cancer: A Role for Bacterial Protein Toxins?

scientific article published on 27 August 2020

High yield purification and first structural characterization of the full-length bacterial toxin CNF1.

scientific article published on 24 October 2017

Hijacking Rho GTPases by protein toxins and apoptosis: molecular strategies of pathogenic bacteria.

scientific article

Hinderance of Apoptosis and Phagocytic Behaviour Induced by Escherichia coli Cytotoxic Necrotizing Factor 1: Two Related Activities in Epithelial Cells

scientific article published on 01 December 1997

Human intestinal microbiota: cross-talk with the host and its potential role in colorectal cancer

scientific article published on 29 September 2010

Human melanoma cells express FGFR/Src/Rho signaling that entails an adhesion-independent caveolin-1 membrane association

scientific article published on 25 May 2011

Inflammation and colorectal cancer, when microbiota-host mutualism breaks

scientific article

Interaction of Clostridium difficile toxin A with cultured cells: cytoskeletal changes and nuclear polarization

scientific article published on July 1990

Interaction of Escherichia coli cytotoxic necrotizing factor type 1 (CNF1) with cultured cells

scientific article published on January 1993

Is the Rac GTPase-activating toxin CNF1 a smart hijacker of host cell fate?

scientific article published on April 2006

Letter to the editors

scientific article published on 01 April 1987

Mitochondrial free radical overproduction due to respiratory chain impairment in the brain of a mouse model of Rett syndrome: protective effect of CNF1.

scientific article published on 20 February 2015

Mode of action of fibrous amphiboles: the case of Biancavilla (Sicily, Italy).

scientific article published on January 2014

Modulation of Rho GTPases rescues brain mitochondrial dysfunction, cognitive deficits and aberrant synaptic plasticity in female mice modeling Rett syndrome.

scientific article published on 30 March 2015

Modulation of RhoGTPases improves the behavioral phenotype and reverses astrocytic deficits in a mouse model of Rett syndrome.

scientific article published on 7 December 2011

Morphometric characterization of NK cell subset expressing the Leu-11 antigen in comparison to Leu-7 Positive, 11 negative cells

scientific article published on 01 November 1986

Multinucleation and pro-inflammatory cytokine release promoted by fibrous fluoro-edenite in lung epithelial A549 cells

scientific article published on 09 February 2006

N -Acetylcysteine protects epithelial cells against the oxidative imbalance due to Clostridium difficile toxins

scientific article published on 01 June 1999

New therapeutics from Nature: The odd case of the bacterial cytotoxic necrotizing factor 1.

scientific article published on 22 March 2018

Occurrence, diversity and pathogenicity of mesophilic Aeromonas in estuarine waters of the Italian coast of the Adriatic Sea.

scientific article

Okadaic acid induces changes in the organization of F-actin in intestinal cells

scientific article published on 01 August 1996

On the mode of action ofClostridium difficile toxin A: anin vitro study

scientific article published on 01 February 1991

Positive modulation by Ras of interleukin-1beta-mediated nitric oxide generation in insulin-secreting clonal beta (HIT-T15) cells

scientific article published on December 2001

Rac GTPase instructs nuclear factor-kappaB activation by conveying the SCF complex and IkBalpha to the ruffling membranes

scientific article published on 10 December 2003

Rho-dependent cell spreading activated by E.coli cytotoxic necrotizing factor 1 hinders apoptosis in epithelial cells

scientific article published on November 1998

Signal transduction pathways and cellular intoxication with Clostridium difficile toxins

scientific article published on 01 May 1993

Surface blebbing and cytoskeletal changes induced in vitro by toxin B from Clostridium difficile: An immunochemical and ultrastructural study

scientific article published on 01 June 1990

The Bacterial Protein CNF1 as a Potential Therapeutic Strategy against Mitochondrial Diseases: A Pilot Study

scientific article published on 21 June 2018

The Bacterial Toxin CNF1 Induces Activation and Maturation of Human Monocyte-Derived Dendritic Cells

scientific article

The Bacterial Toxin CNF1 Protects Human Neuroblastoma SH-SY5Y Cells against 6-Hydroxydopamine-Induced Cell Damage: The Hypothesis of CNF1-Promoted Autophagy as an Antioxidant Strategy

scientific article published on 11 May 2020

The E. coli CNF1 as a pioneering therapy for the central nervous system diseases

scientific article published on 07 January 2014

The Escherichia coli protein toxin cytotoxic necrotizing factor 1 induces epithelial mesenchymal transition

scientific article published on 15 November 2019

The Rac GTPase-activating bacterial protein toxin CNF1 induces analgesia up-regulating mu-opioid receptors.

scientific article

The Rho GTPase activating CNF1 improves associative working memory for object-in-place

scientific article published in April 2010

The Rho-activating CNF1 toxin from pathogenic E. coli: a risk factor for human cancer development?

scientific article published on 12 March 2008

The bacterial protein CNF1 as a new strategy against Plasmodium falciparum cytoadherence

scientific article published on 07 March 2019

The bacterial protein toxin, cytotoxic necrotizing factor 1 (CNF1) provides long-term survival in a murine glioma model

scientific article

The bacterial toxin CNF1 as a tool to induce retinal degeneration reminiscent of retinitis pigmentosa

scientific article published on 24 October 2016

The cytotoxic necrotizing factor (CNF) of Escherichia coli

scientific article published in January 1986

The cytotoxic necrotizing factor 1 from E. coli: a janus toxin playing with cancer regulators.

scientific article published on 14 August 2013

The effect of oxygen on the growth and cell morphology of Helicobacter pylori

scientific article published on 01 November 1998

Toxin-induced activation of Rho GTP-binding protein increases Bcl-2 expression and influences mitochondrial homeostasis

scientific article published on July 1998

Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine

scientific article

Toxins from anaerobic bacteria: specificity and molecular mechanisms of action.

scientific article

Zonula occludens toxin modulates tight junctions through protein kinase C-dependent actin reorganization, in vitro ⬇️

scientific article published on August 1, 1995

p120 Catenin is required for growth factor-dependent cell motility and scattering in epithelial cells

scientific article published on 6 February 2003

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