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List of works by Rachael A. Pearson

ATP released via gap junction hemichannels from the pigment epithelium regulates neural retinal progenitor proliferation

scientific article published in June 2005

Absence of chx10 causes neural progenitors to persist in the adult retina

scientific journal article

Adult ciliary epithelial cells, previously identified as retinal stem cells with potential for retinal repair, fail to differentiate into new rod photoreceptors.

scientific article published in June 2010

Advances in repairing the degenerate retina by rod photoreceptor transplantation

scientific article published on 08 January 2014

Assessment of AAV Vector Tropisms for Mouse and Human Pluripotent Stem Cell-Derived RPE and Photoreceptor Cells

scientific article

Ca(2+) signalling and gap junction coupling within and between pigment epithelium and neural retina in the developing chick

scientific article

Cell transplantation strategies for retinal repair.

scientific article published on January 2009

Cellular strategies for retinal repair by photoreceptor replacement.

scientific article published on 07 February 2015

Comparative analysis of progenitor cells isolated from the iris, pars plana, and ciliary body of the adult porcine eye.

scientific article published on 28 June 2007

Comparative analysis of the retinal potential of embryonic stem cells and amniotic fluid-derived stem cells

scientific article published on 6 December 2010

Conditional Dicer1 depletion using Chrnb4-Cre leads to cone cell death and impaired photopic vision

scientific article published on 19 February 2019

Cone and rod photoreceptor transplantation in models of the childhood retinopathy Leber congenital amaurosis using flow-sorted Crx-positive donor cells.

scientific article

Differentiation and Transplantation of Embryonic Stem Cell-Derived Cone Photoreceptors into a Mouse Model of End-Stage Retinal Degeneration

scientific article published on 25 May 2017

Dominant cone-rod dystrophy: a mouse model generated by gene targeting of the GCAP1/Guca1a gene

scientific article

Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors.

scientific article

EIAV vector-mediated delivery of endostatin or angiostatin inhibits angiogenesis and vascular hyperpermeability in experimental CNV.

scientific article published on 13 June 2006

Effective transplantation of photoreceptor precursor cells selected via cell surface antigen expression.

scientific article published in September 2011

Gap junctions modulate interkinetic nuclear movement in retinal progenitor cells.

scientific article

Gliosis Can Impede Integration Following Photoreceptor Transplantation into the Diseased Retina.

scientific article published on January 2016

Harnessing the Potential of Human Pluripotent Stem Cells and Gene Editing for the Treatment of Retinal Degeneration

scientific article

Isolation and characterisation of neural progenitor cells from the adult Chx10(orJ/orJ) central neural retina.

scientific article published on 10 April 2008

Isolation and culture of adult ciliary epithelial cells, previously identified as retinal stem cells, and retinal progenitor cells

scientific article published in December 2011

Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy

scientific article

Long-term preservation of cones and improvement in visual function following gene therapy in a mouse model of leber congenital amaurosis caused by guanylate cyclase-1 deficiency.

scientific article

Long-term survival of photoreceptors transplanted into the adult murine neural retina requires immune modulation.

scientific article published on November 2010

Migration, integration and maturation of photoreceptor precursors following transplantation in the mouse retina

scientific article published on 18 February 2014

Müller Glia Reactivity and Development of Gliosis in Response to Pathological Conditions

scientific article published on 01 January 2018

Müller glia activation in response to inherited retinal degeneration is highly varied and disease-specific

scientific article (publication date: 2015)

Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina.

scientific article published on 21 July 2013

Photoreceptor replacement therapy: challenges presented by the diseased recipient retinal environment.

scientific article

Pluripotent stem cells and their utility in treating photoreceptor degenerations

scientific article

Prevention of Photoreceptor Cell Loss in a Cln6 Mouse Model of Batten Disease Requires CLN6 Gene Transfer to Bipolar Cells

article

Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors

scientific article

Repair of the degenerate retina by photoreceptor transplantation.

scientific article published on 17 December 2012

Repeated nuclear translocations underlie photoreceptor positioning and lamination of the outer nuclear layer in the mammalian retina

scientific article published on 01 August 2021

Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration

scientific article published on 07 January 2017

Restoration of vision after transplantation of photoreceptors

scientific article published on May 2012

Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina.

scientific article

Tracking neuronal motility in live murine retinal explants

scientific article published on 09 December 2021

Transplantation of Photoreceptor Precursors Isolated via a Cell Surface Biomarker Panel From Embryonic Stem Cell-Derived Self-Forming Retina.

scientific article published on 27 May 2015

Transplanted Donor- or Stem Cell-Derived Cone Photoreceptors Can Both Integrate and Undergo Material Transfer in an Environment-Dependent Manner

scientific article published on 4 January 2018

Unlocking the Potential for Endogenous Repair to Restore Sight

scientific article published on 01 November 2018

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