List of works - Haiyan Jiang

Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress.

scientific article

CD8(+) T-cell responses to adeno-associated virus capsid in humans

scientific article published on 18 March 2007

Comparative study on the response of rat primary astrocytes and microglia to methylmercury toxicity

scientific article

Effects of transient immunosuppression on adenoassociated, virus-mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy

scientific article published on 25 July 2006

Enhanced efficacy of recombinant FVIII in noncovalent complex with PEGylated liposome in hemophilia A mice

scientific article published on 4 August 2009

Evidence of multiyear factor IX expression by AAV-mediated gene transfer to skeletal muscle in an individual with severe hemophilia B.

scientific article published on 5 July 2006

Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID mice

scientific article published on 25 October 2005

Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen.

scientific article published on 15 February 2011

Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver.

scientific article

Multiyear therapeutic benefit of AAV serotypes 2, 6, and 8 delivering factor VIII to hemophilia A mice and dogs

scientific article published on 7 March 2006

Peripheral transvenular delivery of adeno-associated viral vectors to skeletal muscle as a novel therapy for hemophilia B.

scientific article

Phenotypic correction of a mouse model of hemophilia A using AAV2 vectors encoding the heavy and light chains of FVIII.

scientific article published on 31 July 2003

Prolonged activity of a recombinant factor VIII-Fc fusion protein in hemophilia A mice and dogs

scientific article

Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment

scientific article

Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients.

scientific article published on 22 November 2011

Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients

scientific article

Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.

scientific article published on December 2010

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

scientific article (publication date: March 2006)

Sustained phenotypic correction of canine hemophilia A using an adeno-associated viral vector

scientific article published on 8 May 2003

The enhancing effects of the light chain on heavy chain secretion in split delivery of factor VIII gene

scientific article

The methylmercury-L-cysteine conjugate is a substrate for the L-type large neutral amino acid transporter

scientific article published on 13 September 2008

γ-Glutamylcysteine ameliorates oxidative injury in neurons and astrocytes in vitro and increases brain glutathione in vivo.

scientific article

List of works by Haiyan Jiang

Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress.

CD8(+) T-cell responses to adeno-associated virus capsid in humans

Comparative study on the response of rat primary astrocytes and microglia to methylmercury toxicity

Effects of transient immunosuppression on adenoassociated, virus-mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy

Enhanced efficacy of recombinant FVIII in noncovalent complex with PEGylated liposome in hemophilia A mice

Evidence of multiyear factor IX expression by AAV-mediated gene transfer to skeletal muscle in an individual with severe hemophilia B.

Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID mice

Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen.

Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver.

Multiyear therapeutic benefit of AAV serotypes 2, 6, and 8 delivering factor VIII to hemophilia A mice and dogs

Peripheral transvenular delivery of adeno-associated viral vectors to skeletal muscle as a novel therapy for hemophilia B.

Phenotypic correction of a mouse model of hemophilia A using AAV2 vectors encoding the heavy and light chains of FVIII.

Prolonged activity of a recombinant factor VIII-Fc fusion protein in hemophilia A mice and dogs

Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment

Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients.

Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients

Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Sustained phenotypic correction of canine hemophilia A using an adeno-associated viral vector

The enhancing effects of the light chain on heavy chain secretion in split delivery of factor VIII gene

The methylmercury-L-cysteine conjugate is a substrate for the L-type large neutral amino acid transporter

γ-Glutamylcysteine ameliorates oxidative injury in neurons and astrocytes in vitro and increases brain glutathione in vivo.